Table 4 Mean ITT changes in A1C (stratified analyses)
From: Real-world utilization patterns and outcomes of colesevelam hcl in the ge electronic medical record
Stratum | LOCF within day window | Target day | Actual day | N | A1C (%) | ||
|---|---|---|---|---|---|---|---|
Mean | Baseline mean | Post mean | Change mean (95% CI) | ||||
Week 16 | 42 – 140 | 112 | |||||
Monotherapy | 97.2 | 387 | 7.93 | 7.52 | −0.41 (−0.50, -0.32) | ||
Augment/Switch | 97.2 | 745 | 8.26 | 7.90 | −0.36 (−0.44, -0.28) | ||
New Combination | 96.1 | 253 | 8.57 | 7.69 | −0.88 (−1.07, -0.69) | ||
Week 26 | 42 – 210 | 182 | |||||
Monotherapy | 145.0 | 464 | 7.95 | 7.61 | −0.34 (−0.43, -0.25) | ||
Augment/Switch | 146.9 | 939 | 8.29 | 7.97 | −0.31 (−0.39, -0.23) | ||
New Combination | 146.0 | 344 | 8.55 | 7.65 | −0.90 (−1.08, -0.72) | ||
Week 52 | 42 – 395 | 365 | |||||
Monotherapy | 285.9 | 367 | 7.89 | 7.52 | −0.37 (−0.48, -0.26) | ||
Augment/Switch | 300.6 | 939 | 8.29 | 7.96 | −0.33 (−0.41, -0.25) | ||
New Combination | 300.9 | 441 | 8.47 | 7.65 | −0.82 (−0.97, -0.67) | ||