Table 1 UKPDS and framingham risk equations

UKPDS Incident Stevens et al. [3]

$1-exp\left\{-q\left(1-d^t\right)/1-d\right\}\text{,}$ where d = 1.078 and log _e q = −4.4918+ 0.0573× (age-55)−0.6444× female-0.9416× Afro-Caribbean + 0.3001× smoking + 0.1681× (HbA1c-6.72) +0.0843× (SPB-135.7)/10 + 1.3468× {log _e (TC ^a /HDL)-1.59}.

UKPDS Duration

$1-exp\left\{-q{d}^T\left(1-d^t\right)/1-d\right\}\text{,}$ where T = diabetes duration in years, and d and q were defined as above.

Framingham-Initial

Table 6 in Wilson et al. [4]

Male

$1-S_0{\left(t\right)}^{exp\left(m\right)}\text{,}$ where m = 0.0483×Age-0.6595× (TC ^a < 160 mg/dL) + 0.1769×(TC 200-239 mg/dL) + 0.5054×(TC 240-279 mg/dL) + 0.6571×(TC> = 280 mg/dL) + 0.4974×(HDL < 35 mg/dL) + 0.2431× (HDL 35-44 mg/dL)-0.0511× (HDL 50-59 mg/dL)-0.4866× (HDL > =60 mg/dL)-0.0023×(BP Optimal) + 0.2832× (BP High-normal) + 0.5217×(BP Stage-I-hypertension) + 0.6186×(BP Stage-II-IV-hypertension) + 0.4284×Diabetes + 0.5234× (Smoker)-3.0975

S ₀ (1) ^b =0.9946, S ₀ (2) = 0.9850, S ₀ (3) = 0.9770, S ₀ (4) = 0.9622, S ₀ (5) = 0.95592.

Female

$1-S_0{\left(t\right)}^{exp\left(m\right)}\text{,}$ where m = 0.3377×Age-0.0027×age ² -0.2614×(TC ^a < 160 mg/dL) + 0.2077×(TC 200-239 mg/dL)+0.2439×(TC 240-279 mg/dL) + 0.5351×(TC > =280 mg/dL)+0.8431×(HDL < 35 mg/dL) + 0.3780×(HDL 35-44 mg/dL)+0.1979×(HDL 45-49 mg/dL)-0.4295×(HDL > =60 mg/dL)−0.5336×(BP Optimal)-0.0677×(BP High-normal)+0.2629×(BP Stage-I-hypertension) + 0.4657×(BPStage-II-IV-hypertension) + 0.5963×Diabetes + 0.2925×(Smoker)-9.9255

S ₀ (1) ^b =0.9984, S ₀ (2) = 0.9933, S ₀ (3) = 0.9909, S ₀ (4) = 0.9858, S ₀ (5) = 0.98297.

Framingham-Secondary

Male

$1-exp\left(-exp\left\{\left[{log}_e\left(t\right)-m\right]/0.9994\right\}\right)\text{,}$ where m = 4.995–0.0145×age–0.6738× log _e (TC ^a /HDL)-0.3042×Diabetes.

D’Agostino et al. [27]

Female

$1-exp\left(-exp\left\{\left[{log}_e\left(t\right)-m\right]/1.0313\right\}\right)\text{,}$ where m = 13.537-0.0225×age−0.834×log _e (TC ^a /HDL)-1.3713×ln(SBP)-0.7829×Diabetes-0.3669×smoker.