Adverse Event | Incidence Rate per 100 Patient-years†| ||
---|---|---|---|
 | Sitagliptin 100 mg | Non-exposed | Difference between Sitagliptin and Non-exposed (95% CI)* |
Sitagliptin > Non-exposed | Â | Â | Â |
Atrial fibrillation‡ | 0.4 | 0.2 | 0.3 (0.0, 0.6) |
Constipation | 2.6 | 1.9 | 0.8 (0.1, 1.4) |
Protein urine present^ | 0.5 | 0.2 | 0.3 (0.0, 0.5) |
Pain in extremity | 2.8 | 2.1 | 0.7 (0.1, 1.4) |
Dermatitis Contact | 0.7 | 0.3 | 0.5 (0.1, 0.8) |
Non-exposed > Sitagliptin | Â | Â | Â |
Diarrhea# | 6.9 | 9.6 | -2.3 (-3.6, -1.0) |
Fatigue | 1.8 | 2.5 | -0.6 (-1.3, -0.0) |
Blood glucose decreased | 0.5 | 1.0 | -0.5 (-0.9, -0.1) |
Blood glucose increased | 2.3 | 3.6 | -1.3 (-2.1, -0.6) |
Blood triglycerides increased | 0.5 | 0.8 | -0.4 (-0.7, -0.0) |
Hypoglycemia# | 5.2 | 12.1 | -6.8 (-8.3, -5.5) |
Sinus headache | 0.1 | 0.3 | -0.3 (-0.5, -0.1) |