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Table 3 Measurements of subclinical atherosclerosis using flow-mediated dilation of the brachial artery and the carotid intima media thickness in adolescents and young adults with congenital adrenal hyperplasia due to 21-hydroxylase deficiency and age-, sex-, body mass index- and Tanner staged matched controls

From: Cardiovascular risk in Cuban adolescents and young adults with congenital adrenal hyperplasia

 

Patients with CAH

n = 21

Matched controls

n = 22

p-value

CIMT (mm)

0.45 (0.4–0.6)

0.42 (0.2–0.5)

0.07

Increased (n)(> 90 p)

11 (52%)

6 (27%)

0.09

CIMT Right (mm)

0.5 (0.3–0.7)

0.4 (0.3–0.6)

0.10

CIMT Left (mm)

0.5 (0.3–0.6)

0.5 (0.3–0.6)

0.98

FMD, media ± SD

10.6 ± 5.7

10.3 ± 6.2

0.83

Endothelial dysfunction (n)

4 (19%)

2 (9%)

0. 41

Epicardial fat, median (range)

1 (5.8)

1 (2.1)

0.64

Increased (n) ≥ 5 mm

2 (9%)

0 (0%)

0.23

  1. CIMT Carotid intima media thickness, p percentile, FMD flow-mediated dilation