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Table 2 The descriptive indexes and background information homogeneity of the patients suffering from neuropathic pain in pre-intervention and post-intervention stages (two, four, and eight weeks after the initiation of the intervention)

From: Effectiveness of oral clonidine and gabapentin on peripheral neuropathy in diabetic patients in southwestern Iran: a randomized clinical trial

Assessment stages

Variable

Group

Response

Clonidine + Gabapentin

Gabapentin

Homogeneity

Fre

Per

Fre

Per

Statistic

P-value

pre-intervention

Symptoms of diabetic neuropathy in the form of pain

Yes

14

93.3

14

93.3

0

1*

No

1

6.7

1

6.7

Symptoms of diabetic neuropathy in the form of tingling

Yes

15

100

15

100

N/A

N/A

No

N/A

N/A

N/A

N/A

Comorbidity to heart, kidney and mental diseases

Yes

N/A

N/A

N/A

N/A

N/A

N/A

No

15

100

15

100

Medications used to treat diabetes

Ins

5

33.3

6

40

2.61

0.281**

Med

7

46.7

3

20

1via2

3

20

6

40

Medications used to treat the neuropathic complication of diabetes

No

15

100

15

100

N/A

N/A

Gabapentin

N/A

N/A

N/A

N/A

Blood pressure history

Yes

7

46.7

7

46.7

0

1*

No

8

53.3

8

53.3

Complaints about the quality of sexual activity

Yes

13

86.7

7

46.7

6.39

0.035**

No

1

6.7

7

46.7

No spouse

1

6.7

1

6.7

Diapason

1024

N/A

N/A

2

13.3

2.14

0.483*

512

15

100

13

86.7

Two weeks after the start of the intervention

Symptoms of diabetic neuropathy in the form of pain

Yes

3

20

14

93.3

21.85

< 0.001**

No

N/A

N/A

1

6.7

Improved

12

80

N/A

N/A

Symptoms of diabetic neuropathy in the form of tingling

Yes

3

20

15

100

20

< 0.001*

Improved

12

80

N/A

N/A

Complaints about the quality of sexual activity

Yes

5

33.3

7

46.7

13.53

0.002**

No

1

6.7

7

46.7

Improved

8

53.3

 N/A

N/A

No spouse

1

6.7

1

6.7

Four weeks after the start of the intervention

Symptoms of diabetic neuropathy in the form of pain

Yes

N/A

N/A

8

53.3

13.29

< 0.001**

No

N/A

N/A

1

6.7

Improved

15

100

6

40

Symptoms of diabetic neuropathy in the form of tingling

Yes

N/A

N/A

8

53.3

18.48

< 0.001**

No

9

60

N/A

N/A

Improved

6

40

7

46.7

Complaints about the quality of sexual activity

Yes

1

6.7

2

13.3

7.86

0.018**

No

1

6.7

7

46.7

Improved

12

80

5

33.3

No spouse

1

6.7

1

6.7

Eight weeks after the start of the intervention

Symptoms of diabetic neuropathy in the form of pain

Yes

N/A

N/A

7

46.7

9.46

0.006**

No

2

13.3

1

6.7

Improved

13

86.7

7

46.7

Symptoms of diabetic neuropathy in the form of tingling

Yes

N/A

N/A

8

53.3

21.74

< 0.001**

No

11

73.3

 N/A

N/A

Improved

4

26.7

7

46.7

Complaints about the quality of sexual activity

Yes

N/A

N/A

3

20

11.97

0.003**

No

1

6.7

7

46.7

Improved

13

86.7

4

26.7

No spouse

1

6.7

1

6.7

  1. NOTE: Fre = Frequency; Per = Percentage; * Chi-squared test; ** Fisher’s exact test