Skip to main content

Table 5 Subgroup analysis to investigate the relationship between sample size, case and control BMI differences and TG, TC, HDL, LDL

From: Lipid profile in girls with precocious puberty: a systematic review and meta-analysis

Lipid parameters

Sample size

BMI difference

< 50

≥ 50

Yes

No

TG

    

No. of studies

6

8

9

5

I2

90%

60%

90%

19%

SMD(95%CI)

0.99(0.08, 1.91)

0.01(-0.17, 0.19)

0.56(0.07, 1.06)

0.10(-0.07, 0.26)

P

0.03

0.91

0.03

0.25

TC

    

No. of studies

6

6

8

4

I2

91%

2%

90%

9%

SMD(95%CI)

1.03 (0.08, 1.99)

0.04 (-0.07, 0.14)

0.58(0.05, 1.11)

0.10(-0.05, 0.25)

P

0.03

0.52

0.03

0.20

HDL

    

No. of studies

6

7

8

5

I2

69%

70%

82%

0%

SMD(95%CI)

-0.36(-0.84, 0.12)

0.11 (-0.14, 0.36)

-0.23(-0.69, 0.24)

0.04(-0.10, 0.17)

P

0.14

0.38

0.34

0.60

LDL

    

No. of studies

6

7

8

5

I2

92%

85%

93%

65%

SMD(95%CI)

1.16(0.08, 2.23)

0.05(-0.29, 0.40)

0.80(0.00, 1.61)

0.12(-0.15, 0.40)

P

0.03

0.77

0.05

0.38

  1. TG-triglyceride; TC-Total cholesterol; HDL-high density lipoprotein; LDL-low density lipoprotein; SMD-standard mean difference