Table 2 Demographic and clinical characteristics of participants by TyG index
Tertile 1 (n = 96) | Tertile 2 (n = 96) | Tertile 3 (n = 96) | P | |
|---|---|---|---|---|
Gender (male) | 44(45.8) | 49(51.0) | 55(57.3) | 0.655 |
Age (years) | 56.32 ± 12.75 | 58.08 ± 11.33 | 56.97 ± 13.63 | 0.832 |
Smoke [n (%)] | 9 (9.4%) | 14 (14.6%) | 25 (26%)*# | < 0.001 |
Disease duration (years) | 5.09 ± 5.99 | 5.88 ± 4.71 | 8.80 ± 5.75*# | 0.012 |
BMI (kg/m2) | 22.5 ± 3.7 | 22.9 ± 3.8 | 22.8 ± 3.6 | 0.612 |
Hypertension [n (%)] | 16 (16.7%) | 18 (18.8%) | 21 (21.9%) | 0.512 |
SBP (mmHg) | 133.7 ± 16.2 | 135.2 ± 16.9 | 138.1 ± 17.3 | 0.063 |
DBP (mmHg) | 68.9 ± 10.5 | 69.4 ± 11.2 | 69.7 ± 12.1 | 0.071 |
ALT (U/L) | 19.04 ± 8.45 | 23.26 ± 16.94* | 37.05 ± 25.40*# | < 0.001 |
AST (U/L) | 19.85 ± 6.41 | 22.62 ± 10.87* | 35.91 ± 23.21*# | < 0.001 |
Scr (mmol/L) | 63.43 ± 18.86 | 74.17 ± 21.54* | 95.18 ± 36.40*# | < 0.001 |
TC (mmol/L) | 4.17 ± 0.86 | 4.78 ± 1.19 | 5.07 ± 1.28*# | 0.003 |
TG (mmol/L) | 1.12 ± 0.39 | 2.03 ± 0.86* | 3.60 ± 1.53*# | < 0.001 |
HDL-C (mmol/L) | 1.12 ± 0.39 | 1.06 ± 0.19 | 0.99 ± 0.16*# | 0.009 |
LDL-C (mmol/L) | 2.65 ± 0.88 | 2.99 ± 0.89 | 3.33 ± 1.02*# | 0.017 |
UA | 331.59 ± 90.47 | 343.68 ± 110.23 | 366.86 ± 132.87 | 0.394 |
FBG (mmol/L) | 8.09 ± 3.28 | 10.77 ± 4.04* | 14.59 ± 4.52*# | < 0.001 |
HbA1c | 8.31 ± 2.15 | 8.97 ± 1.96 | 10.50 ± 2.38*# | < 0.001 |
Fasting C-peptide | 1.27 ± 1.02 | 1.32 ± 1.16 | 1.32 ± 1.35 | 0.982 |
UACR (mg/g) | 6.58 ± 3.59 | 76.75 ± 11.77* | 174.22 ± 35.37*# | < 0.001 |
TyG index | 7.92 ± 0.35 | 8.78 ± 0.21 | 9.69 ± 0.46*# | < 0.001 |
eGFR | 77.9 ± 15.3 | 68.4 ± 17.2* | 53.7 ± 16.7*# | < 0.001 |