Skip to main content

Table 1 Characteristics of LADA patients with and without CKD

From: Association between a high triglyceride–glucose index and chronic kidney disease in adult patients with latent autoimmune diabetes

 

LADA + non-CKD group (n = 158)

LADA + CKD group (n = 130)

P

Gender (male)

77 (48.7)

71 (54.6)

0.617

Age (years)

55.44 ± 11.55

59.18 ± 13.42

0.118

Smoke [n (%)]

16 (10.1%%)

32 (24.6%)

< 0.001

Disease duration (years)

5.34 ± 5.67

8.10 ± 5.41

0.011

BMI (kg/m2)

22.3 ± 3.6

23.1 ± 3.9

0.524

Hypertension [n (%)]

19 (12%)

36 (27.7%)

< 0.001

SBP (mmHg)

132.5 ± 16.3

135.9 ± 17.2

0.109

DBP (mmHg)

69.3 ± 10.2

69.4 ± 11.5

0.359

ALT (U/L)

20.15 ± 9.53

34.13 ± 25.50

< 0.001

AST (U/L)

20.57 ± 7.93

32.91 ± 21.49

< 0.001

Scr (mmol/L)

58.22 ± 11.78

101.22 ± 27.61

< 0.001

TC (mmol/L)

4.26 ± 1.09

5.18 ± 1.08

< 0.001

TG (mmol/L)

2.00 ± 1.36

2.55 ± 1.53

0.049

HDL-C (mmol/L)

1.10 ± 0.21

1.01 ± 0.15

0.010

LDL-C (mmol/L)

2.69 ± 0.91

3.37 ± 0.91

< 0.001

IL-10 (pg/mL)

1.32 ± 0.11

1.44 ± 0.20

0.057

TNF-α (pg/mL)

5.60 ± 0.78

5.44 ± 0.65

0.075

IL-6 (pg/mL)

1.61 ± 0.32

1.69 ± 0.41

0.064

IL-1β (pg/mL)

2.67 ± 0.44

2.47 ± 0.29

0.051

UA

317.20 ± 87.24

384.2 ± 128.68

0.002

FBG (mmol/L)

9.76 ± 4.58

12.84 ± 4.47

0.001

HbA1c

8.86 ± 2.45

9.75 ± 2.12

0.047

Fasting C-peptide

1.25 ± 1.11

1.37 ± 1.23

0.584

UACR (mg/g)

8.13 ± 1.46

132.56 ± 70.36

< 0.001

TyG index

8.54 ± 0.74

9.11 ± 0.78

< 0.001

eGFR

79.9 ± 13.1

48.9 ± 14.7

0.001

  1. Note: LADA, latent autoimmune diabetes in adults; CKD, chronic kidney disease; BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; ALT, alanine transaminase; AST, aspartate amino transferase; Scr, serum creatinine; TC, serum total cholesterol; TG, triglycerides; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; IL-10, interleukin-10; TNF-α: tumor necrosis factor-α; IL-6, interleukin-6; IL-1β, interleukin-1β; UA, serum uric acid; FBG, fasting blood glucose; HbA1c, glycosylated hemoglobin A1c; UACR, urinary albumin/creatinine ratio; eGFR, estimated glomerular filtration rate; TyG index, the triglyceride-glucose index
Back to article page

BMC Endocrine Disorders

ISSN: 1472-6823

Contact us