Fig. 1

Imaging features of the patient's adrenal lesions and cryptococcal meningitis and immunohistochemistry of adrenal lesions. A: Adrenal CT showed multiple nodules and masses in the bilateral adrenal glands (white arrow). The largest tumor was on the left side, approximately 4.3 × 4.4 cm, with noticeable enhancement. B: Histology and immunohistochemistry (IHC) of adrenal tissues. Hematoxylin and eosin (HE) staining(B1) showed multiple nodular hyperplasia with adenomatoid nodules, immunohistochemistry of CYP11B1 was positive (B2) and CYP11B2 was negative (B3). Scale bar = 2000 μm. C: Head MRI showed bilateral lateral ventricles, the third and fourth ventricles were enlarged, and the meninges were thickened. D: Chest CT show Bilateral scattered inflammation in the lungs and no signs indicated Cryptococcal pneumonia