Skip to main content

Table 2 Measurements and profiles of GHD group pre and post GHRT. Values are displayed as median and (interquartile range)

From: The modulation of platelet function by growth hormone in growth hormone deficient Hypopituitary patients

Measurement

Baseline(n = 13)

Post GHRT(n = 13)

P value

WC(cm)

112(96.5-114.5)

107(98-115.5)

0.26

Systolic BP(mmHg)

115(111.5–127)

121(115.5–134)

0.17

Diastolic BP(mmHg)

80(74-81.5)

79(75-83.5)

0.76

IGF-1(ng/ml)

127.8(101.9-132.25)

181.9(158.1-219.1)

< 0.001***

GH(ng/ml)

0.19(0.07–0.41)

0.29(0.16–0.54)

0.98

TSH(mIU/ml)

1.18(0.81–1.61)

1.16(0.12–1.9)

0.47

T4(pmol/l)

9.3(8.15–12.35)

9(8.15–11.65)

0.32

Haemaglobin(g/dL)

13.8(12.2-14.15)

13.5(12.5–14.7)

1.0

Platelet count(109 /L)

261(222–282)

234(219–272)

0.7

WCC(109 /L)

6.97(5.43–8.92)

6.64(5.29–7.94)

0.33

INR

1.0(0.96-1.0)

0.99(0.94-1.0)

0.38

Creatinine(umol/l)

75(62–83)

69(63-84.5)

0.44

Cholesterol(mmol/l)

5.39(4.48–6.76)

5.61(4.51–6.2)

0.43

LDL(mmol/l)

3.11(2.46–4.63)

2.89(2.61–3.96)

0.55

HDL(mmol/l)

1.35(0.98–1.72)

1.29(0.96–1.57)

0.76

Triglycerides(mmol/l)

1.38(1.13–1.58)

1.35(0.93–1.83)

0.27

Fasting BG(mmol/l)

4.8(4.5–5.25)

4.8(4.4–5.2)

0.71

Testosterone(nmol/l)

19.5(16.9–22.5)

16.1(12.6–21.7)

0.25

Oestrogen females (pg/ml)

95(82–391)

134(77.5-258.5)

0.42

HbA1C(DCCT)

5.4(5.4–5.6)

5.5(5.3–5.6)

0.83

Fasting Insulin(mIU/L)

5.6(2.9–9.55)

6.3(2.8–18.5)

0.04*

Albumin(g/L)

44(41.25–45.75)

42(40-45.5)

0.08

  1. Waist circumference (WC) Insulin-like growth factor I (IGF-1), growth hormone (GH), thyroid-stimulating hormone (TSH), Thyroxine (T4), white cell count, (WCC), international normalised ratio (INR), low-density lipoprotein (LDL), high-density lipoprotein (HDL), Glycated haemoglobin (HbA1C)
  2. Values are displayed as median (Interquartile range). The Wilcoxon matched-pairs signed-rank test was used to compare parameters measured pre and post treatment with GH in the GHD group. Values were considered statistically significant where p < 0.05*, < 0.01**, < 0.001***.