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Table 2 Baseline clinical characteristics of patients stratified by the optimal cutoff point of AIP

From: The relation between atherogenic index of plasma and cardiovascular outcomes in prediabetic individuals with unstable angina pectoris

 

Total population (n = 1096)

Lower AIP (< 0.134; n = 703)

Higher AIP (≥ 0.134; n = 393)

P value

Age, years

59.47 ± 9.86

60.75 ± 9.48

57.17 ± 10.12

< 0.001

Sex, male, n (%)

766 (69.9)

469 (66.7)

297 (75.6)

0.003

BMI, kg/m2

25.90 ± 3.44

25.33 ± 3.44

26.93 ± 3.20

< 0.001

SBP, mmHg

130.17 ± 17.17

130.58 ± 17.45

129.43 ± 16.67

0.287

DBP, mmHg

77.43 ± 10.84

77.27 ± 11.05

77.72 ± 10.47

0.511

Smoking, n (%)

528 (48.2)

309 (44.0)

219 (55.7)

< 0.001

Medical history, n (%)

    

Hypertension

664 (60.6)

419 (59.6)

245 (62.3)

0.409

Dyslipidemia

784 (71.5)

500 (71.1)

284 (72.3)

0.740

Prior PCI

295 (26.9)

187 (26.6)

108 (27.5)

0.807

Laboratory results

    

TG, mmol/L

1.53 ± 1.12

1.04 ± 0.33

2.42 ± 1.45

< 0.001

TC, mmol/L

4.11 ± 1.04

4.00 ± 1.04

4.30 ± 1.02

< 0.001

LDL-C, mmol/L

2.41 ± 0.89

2.34 ± 0.90

2.54 ± 0.86

< 0.001

HDL-C, mmol/L

1.17 ± 0.27

1.26 ± 0.27

1.00 ± 0.18

< 0.001

AIP

0.06 ± 0.28

-0.10 ± 0.17

0.35 ± 0.18

< 0.001

CRP, mg/L

2.41 ± 4.33

2.26 ± 4.46

2.69 ± 4.07

0.111

Cr, mg/dL

71.25 ± 14.98

69.58 ± 13.73

74.24 ± 16.59

< 0.001

eGFR, mL/(min * 1.73 m2

95.43 ± 12.79

95.55 ± 11.65

95.21 ± 14.63

0.672

SUA, µmol/L

350.84 ± 86.07

335.02 ± 80.60

379.12 ± 88.36

< 0.001

FBG, mmol/L

5.93 ± 1.37

5.81 ± 1.27

6.13 ± 1.52

< 0.001

HbA1c, %

5.99 ± 0.22

5.99 ± 0.22

5.99 ± 0.21

0.981

Pre-admission medication, n (%)

    

Antiplatelet therapy

1094 (99.8)

702 (99.9)

392 (99.7)

1

Statins

1091 (99.5)

699 (99.4)

392 (99.7)

0.784

ACEI

148 (13.5)

89 (12.7)

59 (15.0)

0.317

ARB

802 (73.2)

517 (73.5)

285 (72.5)

0.768

nitrate medication

1011 (92.2)

645 (91.7)

366 (93.1)

0.483

β-blocker

878 (80.1)

539 (76.7)

339 (86.3)

< 0.001

Angiographic data

Total population (n = 427)

Lower AIP (< 0.134; n = 271)

Higher AIP (≥ 0.134; n = 156)

 

Target vessel territory, n (%)

    

LM

33 (7.7)

23 (8.5)

10 (6.4)

0.558

LAD

338 (79.2)

223 (82.3)

115 (73.7)

0.048

LCX

230 (53.9)

145 (53.5)

85 (54.5)

0.924

RCA

254 (59.5)

147 (54.2)

107 (68.6)

0.005

SYNTAX score

12.74 ± 7.55

13.04 ± 7.70

12.23 ± 7.28

0.289

  1. BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; PCI: percutaneous coronary intervention; TG: triglyceride; TC: total cholesterol; LDL-C: low density lipoprotein cholesterol; HDL-C: high density lipoprotein cholesterol; AIP: atherogenic index of plasma; CRP: C-reactive protein; Cr: creatinine; eGFR: estimated glomerular filtration rate; SUA: serum uric acid; FBG: fasting blood-glucose; HbA1c: glycosylated hemoglobin A1c; ACEI: angiotensin converting enzyme inhibitor; ARB: angiotensin receptor blocker; LM: left main artery; LAD: left anterior descending artery; LCX: left circumflex artery; RCA: right coronary artery; SYNTAX: synergy between PCI with taxus and cardiac surgery