Fig. 4

circ_072697 regulated AGE-treated HaCaT cell proliferation and migration by directly targeting miR-3150a-3p. A: The relative expression level of miR-3150a-3p in cells transfected with inh-NC or miR-3150a-3p inhibitor. B: CCK-8 assay showed the OD value of cells transfected with si-NC + inh-NC, si-circ_072697#1 + inh-NC, si-NC + miR-3150a-3p inh, or si-circ_072697#1 + miR-3150a-3p inh in 24 h, 48 and 72 h. C: Transwell assay showed the cell migration ability. D: Determination of cellular migration number in different groups. * p < 0.05, ** p < 0.01, *** p < 0.001