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Table 4 Adjusted odds ratios for newly diagnosed diabetes by quartiles of FGF-21 (Compared with pre-diabetes and normoglycemia population)

From: The association of FGF-21 with the risk of newly diagnosed type-2 diabetes mellitus: a cross-sectional study in Southern China

Models

Quartile 1

Quartile 2

Quartile 3

Quartile 4

P trend

Total population

Model 1

1.00

1.48(0.69–3.22)

2.93(1.45–6.16)

4.83(2.43–10.07)

< 0.001

Model 2

1.00

1.49(0.69–3.26)

3.00(1.48–6.33)

4.92(2.47–10.29)

< 0.001

Model 3

1.00

1.30(0.59–2.90)

2.60(1.25–5.59)

3.64(1.77–7.82)

< 0.001

Model 4

1.00

1.24(0.56–2.80)

2.47(1.18–5.33)

3.24(1.53–7.14)

< 0.001

Cluster 1 population

Model 1

1.00

2.35(0.83–7.22)

4.65(1.77–13.81)

2.67(0.86–8.73)

0.022

Model 2

1.00

2.33(0.83–7.17)

4.56(1.72–13.61)

2.63(0.84–8.64)

0.025

Model 3

1.00

2.46(0.86–7.67)

4.99(1.84–15.27)

2.78(0.88–9.27)

0.022

Model 4

1.00

2.36(0.82–7.40)

4.60(1.66–14.33)

2.56(0.79–8.69)

0.044

Cluster 2 population

Model 1

1.00

0.56(0.16–1.94)

1.03(0.32–3.37)

3.04(1.00-9.58)

0.005

Model 2

1.00

0.54(0.15–1.92)

1.05(0.32–3.48)

3.09(1.00-9.92)

0.005

Model 3

1.00

0.51(0.13–1.95)

1.22(0.36–4.19)

3.19(1.00-10.60)

0.004

Model 4

1.00

0.53(0.13–2.05)

1.26(0.37–4.35)

3.53(1.05–12.48)

0.004

  1. Model 1 is unadjusted;
  2. Model 2 is adjusted for sex and age;
  3. Model 3 is adjusted for sex, age, BMI, waistline, and SBP;
  4. Model 4 is adjusted for sex, age, BMI, waistline, SBP, and TG.