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Table 6 Comparison of the incidence of UMRFs and their sets in malignant neoplasms and benign nodules in relation to the FNA result – UC vs. FL

From: The predictive value of sonographic images of follicular lesions – a comparison with nodules unequivocal in FNA – single centre prospective study

Sonographic feature

Results of histopathological examinations

Benign

Malignant

Category of FNA

Category of FNA

UC (200)

No/%

FL (296)

No/%

p

UC (100)

No/%

FL (26)

No/%

p

1 –hypoechogenicity

98/49.0

204/68.9

<0.0001

86/86.0

19/73.1

0.115

2 - solid echostructure (<25% cystic)

115/57.5

227/76.7

<0.0001

94/94.0

24/92.3

0.892

3 (1 & 2) -hypoechogenicity of solid nodule

63/31.5

161/54.4

<0.0001

80/80.0

17/65.4

0.115

4 -taller-than-wide shape

26/13.0

35/11.8

0.696

30/30.0

6/23.1

0.486

5 -pathological vascularization

14/7.0

63/21.3

<0.0001

19/19.0

7/26.9

0.374

6 - suspicious margins

29/14.5

19/6.4

0.003

31/31.0

1/3.8

0.010

7 –calcifications (micro or macro)

27/13.5

34/11.5

0.503

28/28.0

9/34.6

0.509

7a –microcalcifications

4/2.0

14/4.7

0.177

13/13.0

2/7.7

0.686

7b – isolated macrocalcifications

23/11.5

20/6.8

0.065

15/15.0

7/26.0

0.154

Sets of sonographic features

A1 - >2 UMRFs of: 1, 2, 4, 5, 6, 7a

30/15.0

71/24.0

0.015

55/55.0

8/30.8

0.028

A2 - >2 UMRFs of: 1, 2, 4, 5, 6, 7

40/20.0

79/26.7

0.087

63/63.0

12/46.2

0.119

B1 - >2 UMRFs of: 1, 2, 4, 6, 7a (TIRADS)

25/12.5

37/12.5

1.0

46/46.0

6/23.1

0.034

B2 - >2 UMRFs of: 1, 2, 4, 6, 7

33/16.5

46/15.5

0.775

53/53.0

10/38.5

0.187

C - 3 with 4 or 6 or 7a (ATA)

26/13.0

36/12.2

0.782

46/46.0

5/19.2

0.013

D - >2 UMRFs of: 1, 2, 4, 7

20/10.0

37/12.5

0.392

43/43.0

10/38.5

0.676

  1. Statistical significance was marked with bold type
  2. FL follicular lesion, UC unequivocal cytology, UMRFs ultrasonographic malignancy risk features