Sonographic feature | Category of FNA | |||
---|---|---|---|---|
UC OR (95% Cl) p | FL OR (95% Cl) p | |||
univariate analysis | multivariate analysis | univariate analysis | multivariate analysis | |
1 – hypoechogenicity | 6.5 (3.2–13.1) <0.0001 | 4.4 (2.1–9.3) <0.0001 | 3.1 (0.7–13.5) 0.720 | 1.0 (0.4–2.8) 0.948 |
2 - solid echostructure | 11.1 (4.3–28.7) <0.0001 | 10.1 (3.6–28.3) <0.0001 | 1.2 (0.5–3.2) 0.140 | 3.9 (0.8–18.4) 0.082 |
3 (1 & 2) - hypoechogenicity of solid nodule* | 8.7 (4.6–16.3) <0.0001 | 7.0 (3.6–13.5) <0.0001 | 1.5 (0.6–3.6) 0.400 | 1.5 (0.6–3.9) 0.363 |
4 - taller-than-wide shape | 2.9 (1.5–5.4) 0.001 | 2.3 (1.1–4.9) 0.022 | 2.2 (0.8–6.3) 0.149 | 2.0 (0.6–6.0) 0.404 |
5 - pathological vascularization | 3.1 (1.4–6.7) 0.005 | 3.4 (1.3–8.4) 0.009 | 1.4 (0.5–3.6) 0.536 | 1.5 (0.5–4.6) 0.382 |
6 - suspicious margins | 2.7 (1.4–5.0) 0.002 | 1.2 (0.4–2.4) 0.663 | 0.7 (0.1–5.4) 0.722 | 0.3 (0.1–2.4) 0.263 |
7 – calcifications (micro and macro)** | 2.4 (1.3–4.6) 0.006 | 1.7 (0.8–3.5) 0.160 | 4.4 (1.7–11.3) 0.002 | 4.8 (1.8–12.9) 0.002 |
7a-microcalcifications | 7.0 (2.1–23.1) 0.001 | 5.0 (1.2–20.7) 0.024 | 2.0 (0.4–9.7) 0.369 | 3.2 (0.6–17.4) 0.167 |
7b – isolated macrocalcifications | 1.4 (0.6–2.9) 0.425 | 1.1 (0.5–2.6) 0.855 | 5.1 (1.8–14.6) 0.002 | 7.4 (2.3–23.7) 0.001 |