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Table 4 Results of logistic regression analysis in UC and FL nodules for particular UMRFs

From: The predictive value of sonographic images of follicular lesions – a comparison with nodules unequivocal in FNA – single centre prospective study

Sonographic feature

Category of FNA

UC

OR (95% Cl)

p

FL

OR (95% Cl)

p

univariate analysis

multivariate analysis

univariate analysis

multivariate analysis

1 – hypoechogenicity

6.5 (3.2–13.1)

<0.0001

4.4 (2.1–9.3)

<0.0001

3.1 (0.7–13.5)

0.720

1.0 (0.4–2.8)

0.948

2 - solid echostructure

11.1 (4.3–28.7)

<0.0001

10.1 (3.6–28.3)

<0.0001

1.2 (0.5–3.2)

0.140

3.9 (0.8–18.4)

0.082

3 (1 & 2) - hypoechogenicity of solid nodule*

8.7 (4.6–16.3)

<0.0001

7.0 (3.6–13.5)

<0.0001

1.5 (0.6–3.6)

0.400

1.5 (0.6–3.9)

0.363

4 - taller-than-wide shape

2.9 (1.5–5.4)

0.001

2.3 (1.1–4.9)

0.022

2.2 (0.8–6.3)

0.149

2.0 (0.6–6.0)

0.404

5 - pathological vascularization

3.1 (1.4–6.7)

0.005

3.4 (1.3–8.4)

0.009

1.4 (0.5–3.6)

0.536

1.5 (0.5–4.6)

0.382

6 - suspicious margins

2.7 (1.4–5.0)

0.002

1.2 (0.4–2.4)

0.663

0.7 (0.1–5.4)

0.722

0.3 (0.1–2.4)

0.263

7 – calcifications (micro and macro)**

2.4 (1.3–4.6)

0.006

1.7 (0.8–3.5)

0.160

4.4 (1.7–11.3)

0.002

4.8 (1.8–12.9)

0.002

7a-microcalcifications

7.0 (2.1–23.1)

0.001

5.0 (1.2–20.7)

0.024

2.0 (0.4–9.7)

0.369

3.2 (0.6–17.4)

0.167

7b – isolated macrocalcifications

1.4 (0.6–2.9)

0.425

1.1 (0.5–2.6)

0.855

5.1 (1.8–14.6)

0.002

7.4 (2.3–23.7)

0.001

  1. Statistical significance was marked with bold type
  2. FL follicular lesion, UC unequivocal cytology
  3. *multivariate analysis did not consider features 1 and 2 separately
  4. **multivariate analysis did not consider features 7a and 7b separately