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Table 2 Comparison of the incidence of UMRFs and their sets in the nodules histopathologically benign and malignant in UC and FL groups

From: The predictive value of sonographic images of follicular lesions – a comparison with nodules unequivocal in FNA – single centre prospective study

Sonographic feature

Category of FNA

UC (300)

FL (322)

Histopathological results

Histopathological results

Benign (200)

No/%

Malignant (100)

No/%

p

Benign (296)

No/%

Malignant (26)

No/%

p

1 –hypoechogenicity

98/49.0

86/86.0

<0.0001

204/68.9

19/73.1

0.659

2 - solid echostructure

115/57.5

94/94.0

<0.0001

227/76.7

24/92.3

0.111

3 (1 & 2) - hypoechogenicity of solid nodule

63/31.5

80/80.0

<0.0001

161/54.4

17/65.4

0.279

4 - taller-than-wide shape

26/13.0

30/30.0

<0.0001

35/11.8

6/23.1

0.098

5 - pathological vascularization

14/7.0

19/19.0

<0.0001

63/21.3

7/26.9

0.504

6 - suspicious margins

29/14.5

31/31.0

<0.0001

19/6.4

1/3.8

0.922

7 – calcifications (micro or macro)

27/13.5

28/28.0

<0.0001

34/11.5

9/34.6

0.001

7a – microcalcifications

4/2.0

13/13.0

<0.0001

14/4.7

2/7.7

0.845

7b – isolated macrocalcifications

23/11.5

15/15.0

0.535

20/6.8

7/26.0

0.001

Sets of sonographic features

A1 - >2 UMRFs of: 1, 2, 4, 5, 6, 7a

30/15.0

55/55.0

<0.0001

71/24.0

8/30.8

0.441

A2 - >2 UMRFs of: 1, 2, 4, 5, 6, 7

40/20.0

63/63.0

<0.0001

79/26.7

12/46.2

0.035

B1 - >2 UMRFs of: 1, 2, 4, 6, 7a (TIRADS)

25/12.5

46/46.0

<0.0001

37/12.5

6/23.1

0.128

B2 - >2 UMRFs of: 1, 2, 4, 6, 7

33/16.5

53/53.0

<0.0001

46/15.5

10/38.5

0.003

C - 3 with 4 or 6 or 7a (ATA)

26/13.0

46/46.0

<0.0001

36/12.2

5/19.2

0.299

D - >2UMRFs of: 1, 2, 4, 7

20/10.0

43/43

<0.0001

37/12.5

10/38.5

0.001

  1. Statistical significance was marked with bold type
  2. FL follicular lesion, UC unequivocal cytology, UMRFs ultrasonographic malignancy risk features