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Table 2 Three point bending of the femur two-way analysis of variance

From: Genistein treatment improves fracture resistance in obese diabetic mice

 

Lean STD

Lean + GEN

Obese STD

Obese + GEN

Genotype effect (P)

Treatment effect (P)

Genotype * treatment interaction (P)

Midshaft A-P diameter (mm)

2.14 ± 0.05

2.19 ± 0.07

2.09 ± 0.02

2.15 ± 0.05

0.42

0.32

0.86

Ultimate force (N)

13.1 ± 1.47

16.5 ± 1.27

7.4 ± 1.34

12.2 ± 1.61

0.02

0.01

0.63

Deformation to failure (mm)

0.36 ± 0.02

0.52 ± 0.05

0.32 ± 0.02

0.46 ± 0.10

1.00

0.01

0.50

Time to failure (s)

3.00 ± 0.55

3.60 ± 0.24

2.60 ± 0.24

3.40 ± 0.68

0.53

0.16

0.83

Fracture location (% femur length)

48.3 ± 12.6

49.9 ± 9.4

38.4 ± 8.57

45.3 ± 10.0

0.49

0.69

0.80

  1. Data displayed as mean ± SE
  2. STD fed standard chow; GEN fed 600 genistein/kg