Skip to main content
Fig. 2 | BMC Endocrine Disorders

Fig. 2

From: Aldosterone-producing adrenocortical carcinoma with prominent hepatic metastasis diagnosed by liver biopsy: a case report

Fig. 2

Histopathological diagnosis by examination of liver biopsy specimen. a Tumor cells show large conspicuous nuclei, nuclear atypicality, and acidophilic cytoplasm. Cells had a cord-like architectural pattern and alveolar structure (HE staining, original magnification × 400); b Normal hepatocytes (HE, ×400); c These tumor cells are undyed; d Normal hepatocytes became stained (C, D: Hepatocyte paraffin 1 staining, ×400); e-i Immunohistochemical stainings showed positive reactivity (E: Ad4BP/SF1, ×40; F: Ad4BP/SF1, ×400; G: 3β-HSD, ×40; H: P450c21, ×40; I: Inhibinα, ×40). Black arrow: Ad4BP/SF1 was stained in a nucleus. White arrow: steroidogenic enzymes was stained in cytoplasm

Back to article page

BMC Endocrine Disorders

ISSN: 1472-6823

Contact us