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Table 1 IRAS Family Study participant characteristics

From: The uncoupling protein 1 gene, UCP1, is expressed in mammalian islet cells and associated with acute insulin response to glucose in African American families from the IRAS Family Study

 

African American

Hispanic

 

Los Angeles

San Luis Valley

San Antonio

Families (n)

18

12

33

Family members per family (n)

4–51

4–39

6–30

Participantsa (n)

287

318

493

Female gender, %

56.5

52.2

60.0

Diabetes, %

11.6

12.8

17.7

Age, mean ± SD

43.8 ± 14.8

40.3 ± 14.0

43.6 ± 14.8

AIRg μU/mL ± SD

878.4 ± 768.2

808.1 ± 631.5

726.2 ± 620.1

SI, MINMOD, ± SD

1.75 ± 1.22

2.41 ± 2.00

1.95 ± 1.85

BMI, kg/m2 ± SD

28.8 ± 6.5

27.5 ± 5.6

30.1 ± 6.3

Waist, cm ± SD

89.3 ± 14.1

87.3 ± 13.2

92.9 ± 14.7

WHR, ratio ± SD

0.82 ± 0.08

0.85 ± 0.09

0.85 ± 0.08

HDL, mg/dL ± SD

48.3 ± 13.2

43.7 ± 12.4

42.4 ± 12.9

  1. aIncludes only individuals from the IRAS Family Study cohort with at least one UCP1 or UCP2 SNP genotype. Individuals in these families with type 2 diabetes have been excluded from AIRg and SI calculations. AIRg: Acute insulin response to glucose; SI: insulin sensitivity index; WHR: waist-to-hip ratio.
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BMC Endocrine Disorders

ISSN: 1472-6823

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