From: Prevalence and determinants of diabetes mellitus among Iranian patients with chronic liver disease
Patients with cirrhosis | Patients with chronic hepatitis | |||||
---|---|---|---|---|---|---|
Diabetic | Non-diabetic | P-value | Diabetic | Non-diabetic | P-value | |
Number | 22 | 19 | 14 | 88 | ||
Sex | NS | NS | ||||
Female | 4 (18.2%) | 3 (15.8%) | 2 (14.3%) | 12 (13.6%) | ||
Male | 18 (81.8%) | 16 (84.2%) | 12 (85.7%) | 76 (86.4%) | ||
Age | 56.9 ± 10.6 | 46.6 ± 10.0 | 0.003 | 49.7 ± 7.8 | 39.9 ± 10.7 | 0.001 |
CLD etiology | NS | NS | ||||
HBV | 11 (50.0%) | 13 (68.4%) | 10 (71.4%) | 37 (42.0%) | ||
HCV | 8 (36.4%) | 4 (21.1%) | 4 (28.6%) | 51 (58.0%) | ||
Criptogenic | 3 (13.6%) | 2 (10.5%) | - | - | ||
Family history of DM | NS | 0.01 | ||||
Yes | 9 (40.9%) | 3 (15.8%) | 8 (57.1%) | 21 (23.9%) | ||
No | 13 (59.1%) | 16 (84.2%) | 6 (42.9%) | 67 (76.1%) | ||
History of hypertension | NS | NS | ||||
Yes | 6 (27.3%) | 1 (5.3%) | 3 (21.4%) | 8 (9.1%) | ||
No | 16 (72.7%) | 18 (94.7%) | 11 (78.6%) | 80 (90.9%) | ||
BMI | 26.4 ± 3.4 | 26.4 ± 4.0 | NS | 27.7 ± 4.8 | 24.5 ± 3.1 | 0.02 |
Interferon therapy | NS | NS | ||||
Yes | 2 (9.1%) | 3 (15.8%) | 4 (28.6%) | 46 (52.3%) | ||
No | 20 (90.9%) | 16 (84.2%) | 10 (71.4%) | 42 (47.7%) | ||
Smoking | NS | NS | ||||
Yes | 5 (22.7%) | 5 (26.3%) | 7 (50.0%) | 25 (28.4%) | ||
No | 17 (77.3%) | 14 (73.7%) | 7 (50.0%) | 63 (71.6%) | ||
TG | 145.5 ± 58.6 | 109.3 ± 75.2 | NS | 174.9 ± 82.5 | 140.6 ± 53.8 | NS |
Chol | 141.6 ± 50.5 | 151.8± 32.5 | NS | 199.8 ± 42.8 | 163.9 ± 36.1 | NS |
Child-Pugh's score | 0.04 | |||||
Score A | 13 (65.0%) | 18 (94.7%) | - | - | - | |
Score B | 7 (35.0%) | 1 (5.3%) | ||||
Histological staging* | 0.003 | |||||
0–1 | - | - | - | 1 (8.3%) | 33 (41.8%) | |
2–3 | 3 (25.0%) | 30 (38.0%) | ||||
4–6 | 8 (66.7%) | 16 (20.3%) | ||||
Histological grading* | NS | |||||
0–4 | - | - | - | 2 (16.7%) | 36 (45.6%) | |
5–8 | 8 (66.7%) | 34 (43.0%) | ||||
≥ 9 | 2 (16.7%) | 9 (11.4%) |