Figure 1From: Identification of a novel pax8 gene sequence variant in four members of the same family: from congenital hypothyroidism with thyroid hypoplasia to mild subclinical hypothyroidism Pedigree of the family discussed. The arrow indicates the proband. The R133W carriers are evidenced in grey. The subjects II-2, II-5, II-6, III-4, and III-5 were subject to DNA analysis and they did not carry the R133W variant.Back to article page