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Table 2 Clinical types of Kaposi sarcoma (KS)

From: Suspected metastatic adrenocortical carcinoma revealing as pulmonary Kaposi sarcoma in adrenal Cushing’s syndrome

Type of KS

Cutaneous manifestation

Visceral manifestation

Clinical course

Classic (sporadic or Mediterranean)

Yes (often limited to lower extremity)

No (uncommon)

Low malignant potential

Endemic (African)

Yes

Yes

Indolent, occasionally aggressive progression

Epidemic AIDS-associated

Yes

Yes

Indolent, occasionally aggressive progression. May regress with HIV treatment

Latrogenic (immunosuppression-related)

Yes

Yes

May heal spontaneously with reduction or discontinuation of immunosuppression. May be aggressive.

Endogenic (endogenous corticosteroid-excess-related)

Yes (in the literature)

Yes (in our case)

May regress after treatment of hypercortisolism

  1. Endogenic (endogenous corticosteroid-excess-associated) KS represents a potential new form of Kaposi sarcoma.
  2. In bold is underlined the new type of Kaposi sarcoma.