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Figure 3 | BMC Endocrine Disorders

Figure 3

From: Ectopic insulin secreting neuroendocrine tumor of kidney with recurrent hypoglycemia: a diagnostic dilemma

Figure 3

Histopathology. Gross photomicrograph showing a yellow colored well circumscribed tumour in the upper pole of the kidney (3a). Photomicrographs showing diffuse and trabecular arrangement of tumour cells (3b, 3c & 3d) with marked desmoplastic reaction at places (3e). (3b, 3c & 3d: H&E × 400 each, 3e: H&E × 200). Tumour cells are immunoreactive to chromogranin, synaptophysin and insulin (3f, 3g, 3h × 400 each). MIB 1 LI is 2% (d3i × 200). Electron micrographs showing numerous membrane bound electron dense neurosecretory granules, mitochondria and prominent rough endoplasmic reticulum (3j × 2550; 3k × 9000 original magnification).

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