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Figure 3 | BMC Endocrine Disorders

Figure 3

From: Partial deficiency of HIF-1α stimulates pathological cardiac changes in streptozotocin-induced diabetic mice

Figure 3

Protein levels of HIF-1α in the LV of Wt and Hif1a+/- . (A) The HIF-1α protein in nuclear fractions from the isolated LVs of Wt and Hif1a+/- non-diabetic and diabetic hearts was detected by Western blot analysis. A representative immunoblot is shown. (B) Bar graph shows mean ± SEM (n = 4/group) from densitometric analysis. The values are shown as a ratio of HIF-1α/loading control, GAPDH. P values shown are for the interaction of genotype and condition (2-way ANOVA), Tukey’s post-test, *P < 0.05.

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