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Table 2 Specific Gene Ontology groups which were examined in more detail to which genes with changed expression in diaphragm and sternohyoid of diabetic animals were assigned

From: Gene expression of sternohyoid and diaphragm muscles in type 2 diabetic rats

GO group category & specific GO term

Diaphragm # genes

P value

Sternohyoid # genes

P value

Metbolism - Lipid

    

Lipid metabolic process

9

0.019

10

0.012

Long-chain fatty acid transport

2

0.048

3

0.0012

Cellular lipid metabolic process

  

9

0.010

Fatty acid metabolic process

  

6

0.0030

Lipid transport

  

4

0.0077

Fatty acid transport

  

3

0.0021

Metabolism - Carbohydrate

    

Carbohydrate metabolic process

7

0.040

  

Monosaccharide metabolic process

6

0.0037

  

Hexose metabolic process

6

0.0036

  

Cellular carbohydrate metabolic process

6

0.034

  

Carbohydrate biosynthetic process

4

0.016

  

Glycerol-3-phosphate dehydrogenase complex

  

2

0.018

Glycerol-3-phosphate dehydrogenase activity

  

2

0.012

Muscle contraction

    

Sarcomere

4

0.0066

  

Myofibril

4

0.010

  

Contractile fiber part

4

0.010

  

Contractile fiber

4

0.014

  

Striated muscle contraction

3

0.014

  

Muscle system process

  

6

0.0017

Muscle contraction

  

6

0.0015

Regulation of muscle contraction

  

4

0.0022

Ion transport

    

Ion transport

12

0.0015

11

0.0089

Calcium ion binding

9

0.024

12

0.0033

Inorganic anion transport

5

0.0072

5

0.010

Anion transport

5

0.015

6

0.0037

Regulation of ion transport

3

0.014

  

Channel activity

6

0.031

  

Magnesium ion binding

  

5

0.037

Collagen

    

Fibrillar collagen

3

0.0015

3

0.0016

Collagen

3

0.018

4

0.0012

Collagen type I

2

0.013

2

0.012

Blood circulation

    

Blood circulation

5

0.016

  

Circulatory system process

5

0.017

  

Oxidoreductase activity

Oxidoreductase activity

10

0.035

  

Immune & inflammatory

Immune system process

  

10

0.013

Immune response

  

9

0.0033

Defense response

  

8

0.0067

Immune effector process

  

6

0.000076

Acute inflammatory response

  

6

0.000027

Regulation of immune system process

  

6

0.000036

Inflammatory response

  

6

0.0082

Humoral immune response

  

6

7.5E-06

Regulation of immune response

  

6

0.000027

Activation of immune response

  

5

0.000070

Positive regulation of immune system process

  

5

0.00016

Complement activation

  

5

0.000014

Positive regulation of immune response

  

5

0.00013

Innate immune response

  

5

0.00025

Adaptive immune response

  

4

0.0062

Leukocyte mediated immunity

  

4

0.0071

Lymphocyte mediated immunity

  

4

0.0048

Adaptive immune response

  

4

0.0057

B cell mediated immunity

  

4

0.0032

Humoral immune response immunoglobulin

  

3

0.0064

Complement activation-classical pathway

  

3

0.0064

Complement component C1 complex

  

2

0.012

Response to stress & wounding

Response to stress

  

17

0.000096

Response to wounding

  

7

0.023