Skip to main content

Table 3 Comparison of proportions of lymphocyte subpopulations in CMV-seropositive HC and HT

From: Lower CD28+ T cell proportions were associated with CMV-seropositivity in patients with Hashimoto’s thyroiditis

Lymphocyte subpopulation

Healthy controls (HC)

Hashimoto’s thyroiditis (HT)

 

CMV negative (n = 33)

CMV positive (n = 21)

CMV negative (n = 12)

CMV positive (n = 5)

CD28- (% of CD4+)

1.0 ± 0.8 (0.8; 0.1-3.0)

1.9 ± 1.6 (1.9; 0.2-8.4)##

1.0 ± 0.7 (0.9; 0.3-2.7)

1.4 ± 1.4 (1.4; 0.1-2.6)

CD28- (% of CD8+)

9.0 ± 9.4 (5.3; 0.5-32.2)

7.8 ± 14.1 (2.2; 0.2-61.7)

14.5 ± 6.1 (13.3; 4.8-26.4)***

32.6 ± 17.7 (31.4; 12.3-52.3)** #

CD45RO + (% of CD4+)

32.5 ± 12.1 (31.5; 4.7-59.4)

30.7 ± 16.9 (38.4; 1.4-41.9)

44.2 ± 14.1 (43.6; 23.2-74.7)***

50.9 ± 9.2 (47.5; 43.4-66.0)**

CD45RO + (% of CD8+)

18.7 ± 10.4 (15.7; 0.5-48.3)

14.3 ± 8.6 (15.7; 0.07-21.6)

28.5 ± 15.3 (25.6; 11.9-57.8)***

30.5 ± 6.6 (27.7; 24.8-40.1)*

CD45RA + CD62L + (% of CD4+)

61.8 ± 17.6 (65.8; 9.9-88.2)

62.3 ± 12.6 (62.4; 27.5-80.8)

54.8 ± 20.2 (53.3; 10.6-85.3)

53.6 ± 15.5 (60.9; 27.3-66.0)

CD45RA + CD62L + (% of CD8+)

64.2 ± 15.0 (68.5; 16.7-83.6)

61.9 ± 15.5 (61.8; 32.2-93.3)

55.1 ± 14.69 (60.1; 26.5-72.5)

43.9 ± 13.9 (39.2; 31.4-61.8)

CD25 + CD62L + (% of CD4+)

22.4 ± 11.8 (20.5; 4.5-75.5)

23.7 ± 14.5 (19.7; 10.8-78.1)

25.8 ± 7.5 (24.3; 14.2-39.4)

18.4 ± 2.8 (19.4; 14.7-21.1) #

  1. Values are given in mean ± standard deviation (median; range). Numbers (n) of investigated samples from HC and HT are given in brackets. For technical reasons, lymphocyte populations were not investigated in all HC and HT.
  2. Difference between HT and HC in the CMV-positive or CMV-negative groups: *** p < 0.01, ** p < 0.02, * p < 0.05.
  3. Difference between CMV-positive and CMV-negative individuals in the HC or HT groups: ## p < 0.02, # p < 0.05.
Back to article page

BMC Endocrine Disorders

ISSN: 1472-6823

Contact us