Table 1 Mean values ± SD of bone architecture parameters in the femoral head, determined by means of μCT scanning analyses in rats after 4 months of treatment

CORTICAL VOLUME

(Ct.V) (μm³)

31.98 ± 2.449

28.26 ± 1.491^aa

28.59 ± 1.825 ^aa

27.71 ± 2.443 ^aaa

23.36 ± 1.578 ^{aaa, bbb, ccc, ddd}

CORTICAL THICKNESS

(Ct.Th) (μm)

449.4 ± 18.80

422.3 ± 21.21^a

419.5 ± 19.64 ^aa

426.5 ± 18.48 ^a

372.7 ± 15.69 ^{aaa, bbb, ccc, ddd}

TRABECULAR BONE

VOLUME (BV) (μm³)

10.94 ± 1.365

10.69 ± 1.291

11.03 ± 1.176

10.25 ± 1.284

10.17 ± 1.468

TOTAL

VOLUME (TV) (μm³)

20.12 ± 2.062

23.70 ± 2.926 ^a

23.70 ± 2.926 ^aa

21.62 ± 1.737

26.52 ± 1.924 ^{aaa, b, ccc, d}

TRABECULAR

THICKNESS (Tb.Th) (μm)

155.2 ± 6.893

147.2 ± 3.445 ^a

146.2 ± 4.298 ^aa

150.6 ± 4.886

138.9 ± 6.828 ^{aaa, b, ccc, d}

CONNECTIVITY

DENSITY (CD) (1/mm³)

44.42 ± 9.160

46.34 ± 7.634

60.49 ± 20.60

47.26 ± 5.699

46.09 ± 5.317

STRUCTURE MODEL

INDEX (SMI) (0.0-3.0)

0.6509 ± 0.2211

0.9811 ± 0.1391 ^a

0.8556 ± 0.1588

0.9610 ± 0.1824 ^aa

1.179 ± 0.4074 ^aaa,d

TRABECULAR BONE

VOLUME FRACTION (BV/TV)

0.5436 ± 0.04273

0.4511 ± 0.02421 ^aaa

0.4700 ± 0.07018

0.4720 ± 0.03425 ^aa

0.3833 ± 0.05050 ^{aaa, b, cc, d}