Table 3 Mean retinal vessel calibers (CRAE/CRVE) by TCF7L2 rs7903146 genotype, by race

		African American			Caucasian
Retinal Vessel Index	Geno-type	n	Multivariate Adjusted^a	P value^b	n	Multivariate Adjusted^a	P value^b
Mean retinal arteriolar diameter (95% CI), μm	CC	1090	161.61 (160.07, 163.15)	0.49	4096	163.25 (162.42, 164.08)	0.24
	CT	916	161.94 (160.40, 163.48)		3312	162.97 (162.16, 163.79)
	TT	177	162.27 (160.24, 164.29)		694	162.69 (161.65, 163.73)
Mean retinal venular diameter (95% CI), μm	CC	1090	200.36 (198.79, 201.94)	0.32	4096	197.52 (196.69, 198.35)	0.94
	CT	916	199.86 (198.28, 201.45)		3312	197.54 (196.72, 198.36)
	TT	177	199.36 (197.25, 201.47)		694	197.56 (196.51, 198.60)

Abbreviations: CI, confidence interval; CRAE, central retinal artery equivalent; CRVE, central retinal venular equivalent.
^aAdjusted for age, study center, gender, current smoking (yes/no), obesity, total serum cholesterol, total serum triglycerides, mean arterial blood pressure, hypertension, antihypertensive medication, and CRAE (when the outcome is CRVE)/CRVE (when the outcome is CRAE); ^b P value for 1 degree freedom test of association between vessel calibers and rs7903146 under the log additive genetic model.

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