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  1. Vitamin D deficiency is associated with heightened risk of cardiovascular disease. Potential mechanisms include involvement of vitamin D in regulation of renin-angiotensin system and manufacture and secretion ...

    Authors: Hussein F Saadi, M Gary Nicholls, Christopher M Frampton, Sheela Benedict and Javed Yasin
    Citation: BMC Endocrine Disorders 2009 9:4
  2. Traditional high volume aerobic exercise training reduces cardiovascular and metabolic disease risk but involves a substantial time commitment. Extremely low volume high-intensity interval training (HIT) has r...

    Authors: John A Babraj, Niels BJ Vollaard, Cameron Keast, Fergus M Guppy, Greg Cottrell and James A Timmons
    Citation: BMC Endocrine Disorders 2009 9:3
  3. Diabetes has become the single most common cause for end-stage renal disease in the United States. It has been established that mitochondrial damage occurs during diabetes; however, little is known about what ...

    Authors: Shankar Munusamy, Hamida Saba, Tanecia Mitchell, Judit K Megyesi, Robert W Brock and Lee Ann MacMillan-Crow
    Citation: BMC Endocrine Disorders 2009 9:2
  4. Visceral obesity is positively related to insulin resistance. The nature of the relationship between waist circumference and insulin resistance has not been known in Japanese populations. This study examined t...

    Authors: Shinji Tabata, Shinichiro Yoshimitsu, Tadamichi Hamachi, Hiroshi Abe, Keizo Ohnaka and Suminori Kono
    Citation: BMC Endocrine Disorders 2009 9:1
  5. Diabetes mellitus is becoming increasingly common in sub-Saharan Africa. Autonomic dysfunction contributes to morbidity and mortality in diabetic patients. Data on autonomic dysfunction in the African populati...

    Authors: Malvin Torsvik, Amanda Häggblom, Geir Egil Eide, Erich Schmutzhard, Kaare Vetvik and Andrea Sylvia Winkler
    Citation: BMC Endocrine Disorders 2008 8:19
  6. Risk factors underlying the development and progression of some of the less well-recognised complications of type 2 diabetes, including cognitive impairment and non-alcoholic fatty liver disease, are poorly un...

    Authors: Jackie F Price, Rebecca M Reynolds, Rory J Mitchell, Rachel M Williamson, F Gerald R Fowkes, Ian J Deary, Amanda J Lee, Brian M Frier, Peter C Hayes and Mark WJ Strachan
    Citation: BMC Endocrine Disorders 2008 8:18
  7. Angiotensin converting enzyme inhibitors (ACE inhibitors) reduce peripheral vascular resistance via blockage of angiotensin converting enzyme (ACE). ACE inhibitors are commonly used to treat congestive heart f...

    Authors: Maria E Ramos-Nino, Charles D MacLean and Benjamin Littenberg
    Citation: BMC Endocrine Disorders 2008 8:17
  8. Various structural and functional factors of foot function have been associated with high local plantar pressures. The therapist focuses on these features which are thought to be responsible for plantar ulcera...

    Authors: Nick A Guldemond, Pieter Leffers, Geert HIM Walenkamp, Nicolaas C Schaper, Antal P Sanders, Fred HM Nieman and Lodewijk W van Rhijn
    Citation: BMC Endocrine Disorders 2008 8:16
  9. Age- and sex-specific reference intervals are an important prerequisite for interpreting thyroid hormone measurements in children. However, only few studies have reported age- and sex-specific pediatric refere...

    Authors: Klaus Kapelari, Christine Kirchlechner, Wolfgang Högler, Katharina Schweitzer, Irene Virgolini and Roy Moncayo
    Citation: BMC Endocrine Disorders 2008 8:15
  10. Sitagliptin, a highly selective dipeptidyl peptidase-4 inhibitor, is the first in a new class of oral antihyperglycemic agents (AHAs) for the treatment of patients with type 2 diabetes. Type 2 diabetes is a li...

    Authors: Debora Williams-Herman, Elizabeth Round, Arlene S Swern, Bret Musser, Michael J Davies, Peter P Stein, Keith D Kaufman and John M Amatruda
    Citation: BMC Endocrine Disorders 2008 8:14
  11. Non-thyroidal illness syndrome (NTIS) is a characteristic functional constellation of thyrotropic feedback control that frequently occurs in critically ill patients. Although this condition is associated with ...

    Authors: Johannes W Dietrich, Axel Stachon, Biljana Antic, Harald H Klein and Steffen Hering
    Citation: BMC Endocrine Disorders 2008 8:13
  12. Telomeres are DNA repeat sequences necessary for DNA replication which shorten at cell division at a rate directly related to levels of oxidative stress. Critical telomere shortening predisposes to cell senesc...

    Authors: Deepak Kejariwal, Karolina M Stepien, Tracy Smith, Hugh Kennedy, David A Hughes and Mike J Sampson
    Citation: BMC Endocrine Disorders 2008 8:12
  13. Ninety percent of cases of diabetes are of the slowly evolving non-insulin-dependent type, or Type 2 diabetes. Lack of exercise is regarded as one of the main causes of this disorder. In this study we analyzed...

    Authors: Clécia Soares de Alencar Mota, Carla Ribeiro, Gustavo Gomes de Araújo, Michel Barbosa de Araújo, Fúlvia de Barros Manchado-Gobatto, Fabrício Azevedo Voltarelli, Camila Aparecida Machado de Oliveira, Eliete Luciano and Maria Alice Rostom de Mello
    Citation: BMC Endocrine Disorders 2008 8:11
  14. The role of estrogens in male physiology has become evident. However, clinically useful normative data for estradiol secretion in boys has not previously been established due to the insensitivity of current me...

    Authors: Carina Ankarberg-Lindgren and Ensio Norjavaara
    Citation: BMC Endocrine Disorders 2008 8:10
  15. To estimate the proportion of diabetic patients (DPts) with peripheral vascular disease treated at a primary health care site after an endocrinologist-based intervention, who meet ATP III and Steno targets of ...

    Authors: Alejandra Duran, Isabelle Runkle, Pilar Matía, Maria P de Miguel, Sofia Garrido, Emilio Cervera, Maria D Fernandez, Pilar Torres, Tomas Lillo, Patricia Martin, Lucio Cabrerizo, Nuria Garcia de la Torre, Jose R Calle, Jose Ibarra, Aniceto L Charro and Alfonso L Calle-Pascual
    Citation: BMC Endocrine Disorders 2008 8:9
  16. Latent autoimmune diabetes in adults [LADA] is a type 1 diabetes that is slowly developing. This means many people are treated as having type 2 diabetes at diagnosis as they are adults who are not immediately ...

    Authors: Sinead Brophy, Helen Davies, Stephen Bain, Jeffrey W Stephens, Wei-yee Cheung, Kez Richards, Kathie Wareham, Charles Beaverstock, Janet Lloyd, Don Page, Meurig Williams, Ian Russell and Rhys Williams
    Citation: BMC Endocrine Disorders 2008 8:8
  17. In Andalusia there were no studies including a representative sample of children and adolescent population assessing growth and weight increase. Our objectives were to develop reference standards for weight, h...

    Authors: Juan Pedro López-Siguero, Juan Manuel Fernández García, Juan de Dios Luna Castillo, Jose Antonio Moreno Molina, Carlos Ruiz Cosano and Antonio Jurado Ortiz
    Citation: BMC Endocrine Disorders 2008 8(Suppl 1):S1

    This article is part of a Supplement: Volume 8 Supplement 1

  18. The number of people with cardiovascular disease (CVD) and diabetes mellitus type 2 (T2DM) is growing rapidly. To a large extend, this increase is due to lifestyle-dependent risk factors, such as overweight, r...

    Authors: Jeroen Lakerveld, Sandra DM Bot, Marijke J Chinapaw, Maurits W van Tulder, Patricia van Oppen, Jacqueline M Dekker and Giel Nijpels
    Citation: BMC Endocrine Disorders 2008 8:6
  19. Accurate identification of hypoglycemia cases by International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) codes will help to describe epidemiology, monitor trends, and propose in...

    Authors: Adit A Ginde, Phillip G Blanc, Rebecca M Lieberman and Carlos A Camargo Jr
    Citation: BMC Endocrine Disorders 2008 8:4
  20. Insulin resistance and diabetes are associated with increased oxidative stress and impairment of cellular defence systems. Our purpose was to investigate the interaction between glucose metabolism, antioxidati...

    Authors: Mika Venojärvi, Sirkka Aunola, Raivo Puhke, Jukka Marniemi, Helena Hämäläinen, Jukka-Pekka Halonen, Jaana Lindström, Merja Rastas, Kirsti Hällsten, Pirjo Nuutila, Osmo Hänninen and Mustafa Atalay
    Citation: BMC Endocrine Disorders 2008 8:3
  21. Thyroid physiology is closely related to oxidative changes. The aim of this controlled study was to evaluate the levels of nutritional anti-oxidants such as vitamin C, zinc (Zn) and selenium (Se), and to inves...

    Authors: Roy Moncayo, Alexander Kroiss, Manfred Oberwinkler, Fatih Karakolcu, Matthias Starzinger, Klaus Kapelari, Heribert Talasz and Helga Moncayo
    Citation: BMC Endocrine Disorders 2008 8:2
  22. Because of the possible role of cytokines including interleukins (IL) in systemic non-thyroidal illnesses' (NTI) pathogenesis and consequently the frequently associated alterations in thyroid hormone (TH) conc...

    Authors: Hamdy A Abo-Zenah, Sabry A Shoeb, Alaa A Sabry and Hesham A Ismail
    Citation: BMC Endocrine Disorders 2008 8:1
  23. Studies have shown that metabolic syndrome and its consequent biochemical derangements in the various phases of diabetes may contribute to carcinogenesis. A part of this carcinogenic effect could be attributed...

    Authors: K Harish, M Dharmalingam and M Himanshu
    Citation: BMC Endocrine Disorders 2007 7:10
  24. Persons of Pakistani origin living in Oslo have a much higher prevalence of vitamin D deficiency and secondary hyperparathyroidism but similar bone mineral density compared with ethnic Norwegians. Our objectiv...

    Authors: Kristin Holvik, Haakon E Meyer, Anne Johanne Søgaard, Egil Haug and Jan A Falch
    Citation: BMC Endocrine Disorders 2007 7:9
  25. Altered levels of erythrocyte Na+K+-ATPase, atherogenic and anti-atherogenic lipid metabolites have been implicated in diabetic complications but their pattern of interactions remains poorly understood.

    Authors: Bamidele A Iwalokun and Senapon O Iwalokun
    Citation: BMC Endocrine Disorders 2007 7:7
  26. Self management is the cornerstone of effective preventive care in diabetes. Educational interventions that provide self-management skills for people with diabetes have been shown to reduce blood glucose conce...

    Authors: Jyothis T George, Abel Peña Valdovinos, Jonathan C Thow, Ian Russell, Paul Dromgoole, Sarah Lomax, David J Torgerson and Tony Wells
    Citation: BMC Endocrine Disorders 2007 7:6
  27. Basal TSH levels reflect the metabolic status of thyroid function, however the definition and interpretation of the basal levels of TSH is a matter of controversial debate. The aim of this study was to evaluat...

    Authors: Helga Moncayo, Otto Dapunt and Roy Moncayo
    Citation: BMC Endocrine Disorders 2007 7:5
  28. Annual surveillance (with thyroid function testing) is widely recommended for the long-term follow-up of treated hypothyroid patients. It is based largely on consensus opinion and there is limited evidence to ...

    Authors: Ananth K Viswanath, Alison Avenell, Sam Philip, Shamsunder H Acharya, Graeme MacLennan, Katherine Dalziel, Olivia Pereira, Shirley A Copland, John S Bevan and Prakash Abraham
    Citation: BMC Endocrine Disorders 2007 7:4
  29. Cycloset™ is a quick-release formulation of bromocriptine mesylate, a dopamine agonist, which in animal models of insulin resistance and type 2 diabetes acts centrally to reduce resistance to insulin- mediated...

    Authors: Richard E Scranton, J Michael Gaziano, Dean Rutty, Michael Ezrokhi and Anthony Cincotta
    Citation: BMC Endocrine Disorders 2007 7:3
  30. Clinical determination of mid-parental height is an important part of the assessment of a child's growth, however our clinical impression has been that parents cannot be relied upon to accurately report their ...

    Authors: Ieva Braziuniene, Thomas A Wilson and Andrew H Lane
    Citation: BMC Endocrine Disorders 2007 7:2
  31. Variants of uncoupling protein genes UCP1 and UCP2 have been associated with a range of traits. We wished to evaluate contributions of known UCP1 and UCP2 variants to metabolic traits in the Insulin Resistance an...

    Authors: Michèle M Sale, Fang-Chi Hsu, Nicholette D Palmer, Candace J Gordon, Keith L Keene, Hermina M Borgerink, Arun J Sharma, Richard N Bergman, Kent D Taylor, Mohammed F Saad and Jill M Norris
    Citation: BMC Endocrine Disorders 2007 7:1
  32. Secondary involvement of the thyroid gland is rare. Often the origin of the tumor is difficult to identify from the material obtained by fine-needle aspiration cytology. Renal cell carcinoma of the clear-cell ...

    Authors: Maria João M Bugalho, Evelina Mendonça, Patrícia Costa, Jorge Rosa Santos, Eduardo Silva, Ana Luísa Catarino and Luís G Sobrinho
    Citation: BMC Endocrine Disorders 2006 6:6
  33. Recombinant human growth hormone (r-hGH) is used to treat: growth hormone deficiency in children and adults; children born small for gestational age; Turner's syndrome; and chronic renal failure. r-hGH is admi...

    Authors: Hervé Dumas, Paris Panayiotopoulos, Dorothy Parker and Vincent Pongpairochana
    Citation: BMC Endocrine Disorders 2006 6:5
  34. The major cause of primary hypothyroidism is autoimmune mediated with progressive and permanent destruction of the thyroid gland resulting in life-long replacement therapy. Treatable and reversible hypothyroid...

    Authors: Huy A Tran
    Citation: BMC Endocrine Disorders 2006 6:3
  35. Although thyroxin therapy clearly is beneficial to children with frank hypothyroidism there is little data on the effects of thyroxin in children with compensated or subclinical hypothyroidism. The objective o...

    Authors: Naghma J Aijaz, Evelyn M Flaherty, Thomas Preston, Stacey Storch Bracken, Andrew H Lane and Thomas A Wilson
    Citation: BMC Endocrine Disorders 2006 6:2
  36. Most patients with growth hormone deficiency (GHD) show high body mass index. Overweight subjects, but GHD patients, were demonstrated to have high left ventricular mass index (LVMi) and abnormal LV geometric ...

    Authors: Cesare de Gregorio, Lorenzo Curtò, Antonino Recupero, Patrizia Grimaldi, Barbara Almoto, Marilena Venturino, Domenico Cento, Maria Carola Narbone, Francesco Trimarchi, Sebastiano Coglitore and Salvatore Cannavò
    Citation: BMC Endocrine Disorders 2006 6:1
  37. The global pattern of varying prevalence of diseases of affluence, such as obesity, cardiovascular disease and diabetes, suggests that some environmental factor specific to agrarian societies could initiate th...

    Authors: Tommy Jönsson, Stefan Olsson, Bo Ahrén, Thorkild C Bøg-Hansen, Anita Dole and Staffan Lindeberg
    Citation: BMC Endocrine Disorders 2005 5:10
  38. The study aims to assess the pattern of thyroid response to combination Interferon-α2β (IFN-α) and Ribavirin (RBV) anti-viral therapy in an Australian hepatitis C cohort. These include the prevalence of thyroi...

    Authors: Huy A Tran, Tracey L Jones and Robert G Batey
    Citation: BMC Endocrine Disorders 2005 5:8
  39. Genetic variants of proteins involved in lipid metabolism may play an important role in determining the susceptibility for complications associated with type II diabetes mellitus (T2DM). Goal of the present st...

    Authors: Manjusha Dixit, Sandeep Bhattacharya and Balraj Mittal
    Citation: BMC Endocrine Disorders 2005 5:7
  40. The prevalence of diabetes mellitus is higher in individuals with Down syndrome (DS) than in the general population; it may be due to the high prevalence of obesity presented by many of them. The aim of this s...

    Authors: Cristina T Fonseca, Daniela M Amaral, Márcia G Ribeiro, Izabel CR Beserra and Marília M Guimarães
    Citation: BMC Endocrine Disorders 2005 5:6
  41. To investigate whether IGF-I promoter polymorphism was associated with birth weight and risk factors for cardiovascular disease (CVD) and type 2 diabetes (T2DM), and whether the birth weight – risk factor relatio...

    Authors: Saskia J te Velde, Elisabeth FC van Rossum, Paul G Voorhoeve, Jos WR Twisk, Henriette A Delemarre van de Waal, Coen DA Stehouwer, Willem van Mechelen, Steven WJ Lamberts and Han CG Kemper
    Citation: BMC Endocrine Disorders 2005 5:5
  42. Both Diabetes and ageing are associated with reduced vascular endothelial function. The exact relationship between the 2 and any improvements from the insulin sensitizer rosiglitazone have not been explored.

    Authors: Jerrold Petrofsky, Scott Lee and Maria Cuneo
    Citation: BMC Endocrine Disorders 2005 5:4
  43. Diagnostic discordance for osteoporosis is the observation that the T-score of an individual patient varies from one key measurement site to another, falling into two different diagnostic categories identified...

    Authors: Alireza Moayyeri, Akbar Soltani, Nasibeh Khaleghnejad Tabari, Mohsen Sadatsafavi, Arash Hossein-neghad and Bagher Larijani
    Citation: BMC Endocrine Disorders 2005 5:3
  44. Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycaemia. Increased oxidative stress and decreased antioxidant levels are the leading cause of diabetes and diabetic complications. So i...

    Authors: Satyanarayana Sreemantula, Eswar K Kilari, Vishnu A Vardhan and Rajasekhar Jaladi
    Citation: BMC Endocrine Disorders 2005 5:2
  45. Biochemical testing for pheochromocytoma by measurement of fractionated plasma metanephrines is limited by false positive rates of up to 18% in people without known genetic predisposition to the disease. The p...

    Authors: Anna M Sawka, Lehana Thabane, Amiram Gafni, Mitchell Levine and William F Young Jr
    Citation: BMC Endocrine Disorders 2005 5:1

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