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  1. The accumulation of advanced glycation end products (AGEs) occurring in skin tissues can be measured as skin autofluorescence (SAF). Here, we assessed the correlation between SAF values and the complexity and ...

    Authors: Xian Wang, Xingwang Zhao, Tingting Lian, Juanjin Wei, Wanxu Yue, Senwei Zhang and Qiu Chen
    Citation: BMC Endocrine Disorders 2021 21:58
  2. Diabetes is associated with poor coronavirus disease 2019 (COVID-19) outcomes. However, little is known on the impact of undiagnosed diabetes in the COVID-19 population. We investigated whether diabetes, parti...

    Authors: Ye Liu, Ran Lu, Junhong Wang, Qin Cheng, Ruitao Zhang, Shuisheng Zhang, Yunyi Le, Haining Wang, Wenhua Xiao, Hongwei Gao, Lin Zeng and Tianpei Hong
    Citation: BMC Endocrine Disorders 2021 21:56
  3. Obesity is a major risk factor for the development of type 2 diabetes (T2DM) and its complications. Significant weight loss has been shown to improve glycaemia in people with T2DM and obesity. National and int...

    Authors: Arunav Thakur, Dharmesh Sharma, Bhavya Gupta, Nikitha Kramadhari, Rohit Rajagopal, David Simmons and Milan Kumar Piya
    Citation: BMC Endocrine Disorders 2021 21:55
  4. Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease worldwide. Adoption of sedentary life style and westernized diet are shown to be associated with development of NAFLD. Since p...

    Authors: Hadi Emamat, Hamid Ghalandari, Ali Saneei Totmaj, Hadith Tangestani and Azita Hekmatdoost
    Citation: BMC Endocrine Disorders 2021 21:51
  5. Pituitary adenomas are benign brain tumors that cause considerable morbidity and neurological symptoms. SOX9 as a regulatory transcriptional mediator affects normal and tumor cell growth with an undefined role...

    Authors: Farzad Izak Shirian, Mohammad Ghorbani, Mohammad E. Khamseh, Mehrnaz Imani, Mahshid Panahi, Alimohammad Alimohammadi, Mitra Nourbakhsh, Vahid Salimi and Masoumeh Tavakoli-Yaraki
    Citation: BMC Endocrine Disorders 2021 21:50
  6. As the incidence of secretory osteoporosis has increased, bone loss, osteoporosis and their relationships with thyroid-stimulating hormone (TSH) have received increased attention. In this study, the role of TS...

    Authors: Tuo Deng, Wenwen Zhang, Yanling Zhang, Mengqi Zhang, Zhikun Huan, Chunxiao Yu, Xiujuan Zhang, Yan Wang and Jin Xu
    Citation: BMC Endocrine Disorders 2021 21:49
  7. Type 2 diabetes is more frequent in Latin American people than in non-Hispanic whites due to a combination of genetic and lifestyle risk factors. Brazil and Mexico are the most populous countries in Latin Amer...

    Authors: Renata Breda Martins, Sandra Azucena Ordaz-Briseño, Sarahí Flores-Hernández, Ângelo José Gonçalves Bós, Raúl C. Baptista-Rosas and Arieh Roldán Mercado-Sesma
    Citation: BMC Endocrine Disorders 2021 21:48
  8. NKX6.1 is a transcription factor for insulin, as well as a marker for β cell maturity. Abnormal NKX6.1 expression in β cells, such as translocation from the nucleus to cytoplasm or lost expression, has been sh...

    Authors: Tengli Liu, Peng Sun, Jiaqi Zou, Le Wang, Guanqiao Wang, Na Liu, Yaojuan Liu, Xuejie Ding, Boya Zhang, Rui Liang, Shusen Wang and Zhongyang Shen
    Citation: BMC Endocrine Disorders 2021 21:47
  9. Home care services plays an important role in diabetes management, and to enable older adults remain home-dwellers. Adequate follow-up and systematic nursing documentation are necessary elements in high qualit...

    Authors: Lovise S. Heimro, Monica Hermann, Therese Thuen Davies, Anne Haugstvedt, Johannes Haltbakk and Marit Graue
    Citation: BMC Endocrine Disorders 2021 21:46
  10. Polycystic ovarian syndrome (PCOS) is the most common endocrinopathy among young women. Insulin resistance is a key feature in the pathogenesis of PCOS; also high molecular weight adiponectin is a marker of in...

    Authors: Farnaz Kamali Haghighi Shirazi, Zohre Khodamoradi and Marjan Jeddi
    Citation: BMC Endocrine Disorders 2021 21:45
  11. The human ovary is the target of autoimmune attack in cases of autoimmune disorders, which can cause ovarian dysfunction. Due to the higher prevalence of Hashimoto’s Thyroiditis (HT) in Polycystic Ovary Syndro...

    Authors: Aliye Nigar Serin, Özer Birge, Aysel Uysal, Süheyla Görar and Feyza Tekeli
    Citation: BMC Endocrine Disorders 2021 21:44
  12. Subclinical hypothyroidism (SCH) is reportedly associated with an increased risk of adverse events in patients undergoing percutaneous coronary intervention (PCI). The prognostic significance of SCH in the eld...

    Authors: Yong-Sheng Liu, Mei Wei, Le Wang, Gang Liu, Guo-Ping Ma, Katsushige Ono, Ze-Long Cao, Man Yang and Ming-Qi Zheng
    Citation: BMC Endocrine Disorders 2021 21:43
  13. Type 2 diabetes in the Gulf Cooperation Council countries, including Oman, is currently the fastest growing health crisis and is a significant cause of premature mortality and disability. There is currently in...

    Authors: Adhra Al-Mawali, Ayaman Al-Harrasi, Sathish Kumar Jayapal, Magdi Morsi, Avinash Daniel Pinto, Waleed Al-Shekaili, Hilal Al-Kharusi, Zainab Al-Balushi and John Idikula
    Citation: BMC Endocrine Disorders 2021 21:42
  14. Gestational diabetes mellitus (GDM) causes many problems for mother and her neonate. A healthy diet plays an important role in preventing GDM. This study aimed to investigate the relationship between major die...

    Authors: Abazar Roustazadeh, Hamed Mir, Sima Jafarirad, Farideh Mogharab, Seyed Ahmad Hosseini, Amir Abdoli and Saiedeh Erfanian
    Citation: BMC Endocrine Disorders 2021 21:41
  15. Metabolic syndrome (Mets) is prevalent in the general population and has been reported to be an independent risk factor for cognitive impairment. This study aimed to investigate the association of Mets with th...

    Authors: Xiaohui Wang, Long Ji, Zhaoyang Tang, Guoyong Ding, Xueyu Chen, Jian Lv, Yanru Chen and Dong Li
    Citation: BMC Endocrine Disorders 2021 21:40
  16. Recently, the relationship between thyroid hormones (THs) across the euthyroid ranges and metabolic syndrome (MetS) has been widely discussed. This study aimed to present specific cutoff values of THs to asses...

    Authors: Xi Ding, Chun-Ying Zhu, Rui Li, Li-Ping Wu, Yue Wang, Shi-Qian Hu, Yi-Ming Liu, Feng-Yi Zhao, Yang Zhao, Meng Zhang, Ming-Qian He, Zi-Yi Chen and Bing-Yin Shi
    Citation: BMC Endocrine Disorders 2021 21:39
  17. The incidence of thyroid nodules is increasing year by year around the world. However, ultrasound is not recommended as a screening test for the general population or patients with a normal thyroid on palpatio...

    Authors: Zhi Chen, Singla Sethiel Mosha, Tong Zhang, Ming Xu, Yanli Li, Zhuoqing Hu, Weiqiang Liang, Xiaoyi Deng, Tingting Ou, Ling Li and Wangen Li
    Citation: BMC Endocrine Disorders 2021 21:38
  18. This study aimed to develop and validate a nomogram for predicting acute kidney injury (AKI) during the Intensive Care Unit (ICU) stay of patients with diabetic ketoacidosis (DKA).

    Authors: Tingting Fan, Haosheng Wang, Jiaxin Wang, Wenrui Wang, Haifei Guan and Chuan Zhang
    Citation: BMC Endocrine Disorders 2021 21:37
  19. Transsphenoidal surgery (TSS) to resect an adrenocorticotropic hormone (ACTH)-secreting pituitary adenoma is the first-line treatment for Cushing’s disease (CD), with increasing usage of endoscopic transspheno...

    Authors: Zarina Brady, Aoife Garrahy, Claire Carthy, Michael W. O’Reilly, Christopher J. Thompson, Mark Sherlock, Amar Agha and Mohsen Javadpour
    Citation: BMC Endocrine Disorders 2021 21:36
  20. Levothyroxine replacement therapy may decrease the risk of adverse pregnancy outcomes among women with subclinical hypothyroidism (SCH). The aim of this study is to conduct a systematic review and meta-analysi...

    Authors: Magnus Bein, Oriana Hoi Yun Yu, Sonia Marzia Grandi, Francesca Y. E. Frati, Ihab Kandil and Kristian B. Filion
    Citation: BMC Endocrine Disorders 2021 21:34
  21. Immune checkpoint inhibitors (ICIs) are a novel class of oncological agents which are used to treat a number of malignancies. To date seven agents have been approved by the Food and Drug Administration (FDA) t...

    Authors: Christine Newman, Oratile Kgosidalwa, Osamah A. Hakami, Carmel Kennedy, Liam Grogan and Amar Agha
    Citation: BMC Endocrine Disorders 2021 21:33
  22. Insulin resistance (IR) in skeletal muscle is a key feature of the pre-diabetic state, hypertension, dyslipidemia, cardiovascular diseases and also predicts type 2 diabetes. However, the underlying molecular m...

    Authors: Hemang M. Parikh, Targ Elgzyri, Amra Alibegovic, Natalie Hiscock, Ola Ekström, Karl-Fredrik Eriksson, Allan Vaag, Leif C. Groop, Kristoffer Ström and Ola Hansson
    Citation: BMC Endocrine Disorders 2021 21:32
  23. Multiple endocrine neoplasia type 1 (MEN1) is a rare inherited syndrome that concurrently involves various endocrine glands. We report a rare case of MEN1 in a 43-year-old man whose first manifestation was an ...

    Authors: Ji Eun Jun, You-Cheol Hwang, Kyu Jeong Ahn, Ho Yeon Chung and In-Kyung Jeong
    Citation: BMC Endocrine Disorders 2021 21:31
  24. Studies of drug utilization in patients with diabetes, a chronic disease that can be treated with a wide range of available medicines, have attracted substantial social and clinical interest.

    Authors: Artur Mendes Moura, Sofia Oliveira Martins and João Filipe Raposo
    Citation: BMC Endocrine Disorders 2021 21:30
  25. Cushing’s syndrome occurs due to overproduction of cortisol from adrenal glands. Endogenous hypercortisolemia can occur secondary to adrenocorticotropic hormone (ACTH) dependent as well as independent causes. ...

    Authors: Piyumi Sachindra Alwis Wijewickrama, Vithiya Ratnasamy, Noel P. Somasundaram, Manilka Sumanatilleke and Sathyajith Buddhika Ambawatte
    Citation: BMC Endocrine Disorders 2021 21:29
  26. Advanced glycation end-products (AGEs) are heterogeneous molecules produced by the non-enzymatic glycation of proteins, lipids, or nucleic acids during hyperglycaemia. Accumulation of AGEs in the peripheral ne...

    Authors: Stella Papachristou, Kalliopi Pafili and Nikolaos Papanas
    Citation: BMC Endocrine Disorders 2021 21:28
  27. Although thyroid function has been demonstrated to be associated with non-alcoholic fatty liver disease (NAFLD) in different population, the prevalence and features of NAFLD in hyperthyroidism have not been re...

    Authors: Bairong Wang, Baomin Wang, Yumei Yang, Jing Xu, Mengyang Hong, Mingfeng Xia, Xiaomu Li and Xin Gao
    Citation: BMC Endocrine Disorders 2021 21:27
  28. Diabetes Mellitus (DM) is a metabolic disorder associated with acute and chronic complications. Diabetic ketoacidosis (DKA) is the most serious diabetic emergency in patients with type one and type two diabete...

    Authors: Addisu Getie, Adam Wondmieneh, Melaku Bimerew, Getnet Gedefaw and Asmamaw Demis
    Citation: BMC Endocrine Disorders 2021 21:26
  29. Hyperuricemia is associated with insulin resistance, pancreatic β-cell dysfunction and consequently with development of type 2 diabetes. Although a direct relationship between high levels of uric acid (UA) and...

    Authors: Asghar Ghasemi
    Citation: BMC Endocrine Disorders 2021 21:24
  30. Bullous pemphigoid is the most common bullous chronic autoimmune skin disease. Recent studies have suggested dipeptidyl-peptidase 4 inhibitors as possible predisposing agents of bullous pemphigoid. The objecti...

    Authors: Vaia Lambadiari, Aikaterini Kountouri, Foteini Kousathana, Emmanouil Korakas, Georgios Kokkalis, Sofia Theotokoglou, Lina Palaiodimou, Pelagia Katsimbri, Ignatios Ikonomidis, Konstantinos Theodoropoulos and Evangelia Papadavid
    Citation: BMC Endocrine Disorders 2021 21:23
  31. Adrenal vein sampling (AVS) is the preferred method for subtyping patients with primary aldosteronism, while the procedure is technically challenging. This study evaluated the feasibility and effectiveness of ...

    Authors: Jindong Wan, Fei Ran, Siwei Xia, Jixin Hou, Dan Wang, Sen Liu, Yi Yang, Peng Zhou and Peijian Wang
    Citation: BMC Endocrine Disorders 2021 21:22
  32. Previous studies have indicated inconsistent relationships of diabetes with thyroid cancer risk, yet little is known in China. In this study, we aimed to investigate the associations between diabetes, diabetes...

    Authors: Meng Wang, Wei-Wei Gong, Feng Lu, Ru-Ying Hu, Qing-Fang He and Min Yu
    Citation: BMC Endocrine Disorders 2021 21:21
  33. Familial hypocalciuric hypercalcemia (FHH) is a heterogeneous autosomal-dominant disorder of calcium hemostasis that may be difficult to distinguish clinically from mild primary hyperparathyroidism. Loss-of-fu...

    Authors: Noha N Mukhtar, Mohei El-Din M Abouzied, Mohammed H Alqahtani and Muhammad M Hammami
    Citation: BMC Endocrine Disorders 2021 21:20
  34. The present study aimed to evaluate the effect of artesunate (ART) on the reduction of cardiovascular complications in a type 1 diabetes model and to investigate the associated mechanism based on the receptor ...

    Authors: Yi Chen, Wei Li, Xiaolin Nong, Chen Liang, Jiaquan Li, Wei Lu, Bingge Wang, Zhong Yuan and Shiying Yang
    Citation: BMC Endocrine Disorders 2021 21:19
  35. Currently, there is a lack of data relating to glycemic parameters and their relationship with C-peptide (CP) and proinsulin (PI) during the partial remission period (PRP) in type 1 diabetes mellitus (T1D). Th...

    Authors: Gül Yeşiltepe-Mutlu, Merve Çapacı, Ecem Can, Tuğba Gökçe, Gizem Bayrakçı, Serra Muradoğlu, Said İncir, Esra Papatya Çakır and Şükrü Hatun
    Citation: BMC Endocrine Disorders 2021 21:18
  36. Diabetic retinopathy is the most common microvascular complication of diabetes and it is a leading cause of visual impairment and blindness among patients with diabetes. This study aimed to investigate the eff...

    Authors: Seyed Shahriar Hosseini, Mohsen Shamsi, Mahboobeh Khorsandi and Rahmatollah Moradzadeh
    Citation: BMC Endocrine Disorders 2021 21:17
  37. Long-term antithyroid drug therapy has become one of the options for treatment of Graves’ hyperthyroidism. The aim of this study was to compare thyroid status in those who discontinued methimazole (MMI) treatm...

    Authors: Fereidoun Azizi, Hengameh Abdi and Atieh Amouzegar
    Citation: BMC Endocrine Disorders 2021 21:16
  38. Functional gonadotroph adenomas (FGAs) are rare adenomas that most commonly secrete FSH. However, solitary LH-secreting pituitary adenomas are unusual.

    Authors: Yi Zhang, Cheng Chen, Min Lin, Kan Deng, Huijuan Zhu, Wenbin Ma, Hui Pan, Renzhi Wang and Yong Yao
    Citation: BMC Endocrine Disorders 2021 21:15
  39. Skin autofluorescence (SAF) is a non-invasive marker of tissue accumulation of advanced glycation endproducts (AGE). Recently, we demonstrated in the general population that elevated SAF levels predict the dev...

    Authors: Henderikus E. Boersma, Robert P. van Waateringe, Melanie M. van der Klauw, Reindert Graaff, Andrew D. Paterson, Andries J. Smit and Bruce H. R. Wolffenbuttel
    Citation: BMC Endocrine Disorders 2021 21:14
  40. Primary central nervous system lymphoma is a rare extra-nodal lymphoma of the central nervous system. Primary central nervous system lymphoma lesions usually appear in the vicinity of the ventricle, and there ...

    Authors: Ken Takao, Ayaka Tani, Tetsuya Suwa, Yayoi Kuwabara-Ohmura, Kenta Nonomura, Yanyan Liu, Takehiro Kato, Masami Mizuno, Takuo Hirota, Mayumi Enya, Katsumi Iizuka, Yukio Horikawa, Chiemi Saigo, Yusuke Kito, Tatsuhiko Miyazaki, Naoyuki Ohe…
    Citation: BMC Endocrine Disorders 2021 21:13
  41. Pseudohypoparathyroidism is a rare genetic disease characterized by hypocalcaemia and hyperphosphataemia due to the defect to the guanine nucleotide-binding protein alpha subunit (GNAS) gene. Patients with pse...

    Authors: Difei Lu, Aimei Dong, Junqing Zhang and Xiaohui Guo
    Citation: BMC Endocrine Disorders 2021 21:12
  42. Endogenous Cushing’s syndrome (CS) results in increased cardiovascular (CV) morbidity and mortality. So far, most studies focussed on distinct disease entities rather than the integrity of the CV system. We he...

    Authors: Kristina Ehrlich, Caroline Morbach, Theresa Reiter, Peter Ulrich Heuschmann, Anke Hannemann, Martin Fassnacht, Stefan Störk, Stefanie Hahner and Timo Deutschbein
    Citation: BMC Endocrine Disorders 2021 21:11
  43. Neuroendocrine tumors (NETs) are rare tumors harboring overexpression of somatostatin receptors (SSTRs) on their cell membrane. Because some organs, such as the spleen, adrenal glands and liver, physiologicall...

    Authors: Emre Gezer, Berrin Çetinarslan, Dilek Karakaya, Zeynep Cantürk, Alev Selek, Mehmet Sözen and Serkan İşgören
    Citation: BMC Endocrine Disorders 2021 21:6
  44. Hypercalcemia of malignancy is relatively common in several cancers. However, in colorectal cancer, paraneoplastic phenomena that cause hypercalcemia is uncommon. In the few cases that are reported, secretion ...

    Authors: Vegard Heimly Brun, Erik Knutsen, Helge Stenvold and Hanne Halvorsen
    Citation: BMC Endocrine Disorders 2021 21:4

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