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  1. We aimed to investigate the clinical characteristics and islet β-cell function in patients with Klinefelter syndrome (KS) and hyperglycemia.

    Authors: Shixuan Liu, Tao Yuan, Shuoning Song, Shi Chen, Linjie Wang, Yong Fu, Yingyue Dong, Yan Tang and Weigang Zhao
    Citation: BMC Endocrine Disorders 2021 21:239
  2. Graves’ disease (GD) is one of the most common autoimmune thyroid diseases (AITDs) in humans, and thyrotropin receptor antibody (TRAb) is a characterized autoantibody in GD. The use of radioactive iodine thera...

    Authors: Ya Fang, Wen-Hua Du, Cao-Xu Zhang, Shuang-Xia Zhao, Huai-Dong Song, Guan-Qi Gao and Mei Dong
    Citation: BMC Endocrine Disorders 2021 21:238
  3. Our study aims to summarize the clinical characteristics of rare types of congenital adrenal hyperplasia (CAH) other than 21-hydroxylase deficiency (21-OHD), and to explore the clinical applications of genetic...

    Authors: Zhuoguang Li, Yan Liang, Caiqi Du, Xiao Yu, Ling Hou, Wei Wu, Yanqing Ying and Xiaoping Luo
    Citation: BMC Endocrine Disorders 2021 21:237
  4. Prolactinoma is a functional pituitary adenoma that secretes excessive prolactin. Dopamine agonists (DAs) such as bromocriptine (BRC) are the first-line treatment for prolactinomas, but the resistance rate is ...

    Authors: Shuman Wang, Aihua Wang, Yu Zhang, Kejing Zhu, Xiong Wang, Yonggang Chen and Jinhu Wu
    Citation: BMC Endocrine Disorders 2021 21:235
  5. Polycystic Ovary Syndrome (PCOS) is a common endocrine disorder affecting up to 13 % of women. Lifestyle interventions are first-line treatments, however attrition in women with PCOS is high. This review summa...

    Authors: Carolyn Ee, Stephanie Pirotta, Aya Mousa, Lisa Moran and Siew Lim
    Citation: BMC Endocrine Disorders 2021 21:234
  6. A number of studies have identified patient-, provider-, and community-level barriers to effective diabetes management among South Asian Americans, who have a high prevalence of type 2 diabetes. However, no mu...

    Authors: Sahnah Lim, Laura C. Wyatt, Shinu Mammen, Jennifer M. Zanowiak, Sadia Mohaimin, Andrea B. Troxel, Stacy Tessler Lindau, Heather T. Gold, Donna Shelley, Chau Trinh-Shevrin and Nadia S. Islam
    Citation: BMC Endocrine Disorders 2021 21:233
  7. The PARADIGHM registry of adult and pediatric patients with chronic hypoparathyroidism evaluates the long-term safety and effectiveness of treatment with recombinant human parathyroid hormone, rhPTH(1-84), and...

    Authors: Neil Gittoes, Lars Rejnmark, Steven W. Ing, Maria Luisa Brandi, Sigridur Björnsdottir, Stefanie Hahner, Lorenz C. Hofbauer, Pascal Houillier, Aliya A. Khan, Michael A. Levine, Michael Mannstadt, Dolores M. Shoback, Tamara J. Vokes, Pinggao Zhang, Claudio Marelli, John Germak…
    Citation: BMC Endocrine Disorders 2021 21:232
  8. Nonalcoholic fatty liver disease (NAFLD) and gallstone disease (GSD) often coexist in the general population owing to shared risk factors. This study explored the relationship between NAFLD and GSD in patients...

    Authors: Ye Lu, Lili Hu, Jing Song, Jing Wan, Haibing Chen and Jun Yin
    Citation: BMC Endocrine Disorders 2021 21:231
  9. Myxedema coma, which occurs due to hypothyroidism, is a rare and life-threatening condition. Some patients have hemodynamic dysfunction, which consequently leads to cardiac arrest. The rarity of this condition...

    Authors: Asami Yoshinaka, Masayuki Akatsuka, Shuji Yamamoto and Michiaki Yamakage
    Citation: BMC Endocrine Disorders 2021 21:229
  10. The outbreak of severe acute respiratory syndrome novel coronavirus 2 (SARS-CoV-2) has spread rapidly worldwide. SARS-CoV-2 has been found to cause multiple organ damage; however, little attention has been pai...

    Authors: Juan Zheng, Zhenhai Cui, Ningjie Shi, Shenghua Tian, Ting Chen, Xueyu Zhong, Kangli Qiu, Jiaoyue Zhang, Tianshu Zeng, Lulu Chen and Huiqing Li
    Citation: BMC Endocrine Disorders 2021 21:228
  11. Although there is a strong association between obesity and obstructive sleep apnoea (OSA), the effects of OSA and CPAP therapy on weight loss are less well known. The aim of this study in adults with class 3 o...

    Authors: Sophie Kobuch, Fiona Tsang, Ritesh Chimoriya, Daniel Gossayn, Sarah O’Brien, Javeria Jamal, Leon Laks, Abd Tahrani, Nic Kormas and Milan K Piya
    Citation: BMC Endocrine Disorders 2021 21:227
  12. Quantitatively staging TAO using MRI remains limited. Our study aims to identify the cut-off signal intensity value for staging TAO using STIR sequence scan.

    Authors: Qian Ge, Xiaohui Zhang, Lu Wang, Yao Fan, Qian Huang, Ning Yao, Jian Long and Chun Liu
    Citation: BMC Endocrine Disorders 2021 21:226
  13. Prolactinoma is the major cause of hyperprolactinemia, and dopamine agonists (DAs) are generally the first-line treatment for them. Several studies have reviewed the recurrent rate of hyperprolactinemia after ...

    Authors: Yunzhi Zou, Depei Li, Jiayu Gu, Siyu Chen, Xia Wen, Jiajun Dong and Xiaobing Jiang
    Citation: BMC Endocrine Disorders 2021 21:225
  14. Many smaller studies have previously shown a significant association between thyroid autoantibody induced hypothyroidism and lower serum vitamin D levels. However, these finding have not been confirmed by larg...

    Authors: Sandeep Appunni, Muni Rubens, Venkataraghavan Ramamoorthy, Anshul Saxena, Raees Tonse, Emir Veledar and Peter McGranaghan
    Citation: BMC Endocrine Disorders 2021 21:224
  15. Maturity Onset Diabetes of the Young (MODY) is an autosomal dominant type of diabetes. Pathogenic variants in fourteen genes are reported as causes of MODY. Its symptoms overlap with type 1 and type 2 diabetes...

    Authors: Ibrar Rafique, Asif Mir, Muhammad Arif Nadeem Saqib, Muhammad Naeem, Luc Marchand and Constantin Polychronakos
    Citation: BMC Endocrine Disorders 2021 21:223
  16. Self-monitoring of blood glucose (SMBG) has been shown to reduce hemoglobin A1C (HbA1C). Accordingly, guidelines recommend SMBG up to 4–10 times daily for adults with type 2 diabetes (T2DM) on insulin. For per...

    Authors: Alex R. Montero, David Toro-Tobon, Kelly Gann, Carine M. Nassar, Gretchen A. Youssef and Michelle F. Magee
    Citation: BMC Endocrine Disorders 2021 21:222
  17. The term non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) was recently proposed as a non-malignant thyroid lesion with indolent behavior that does not require post-operativ...

    Authors: Yasaman Fakhar, Alireza Khooei, Atena Aghaee, Hadis Mohammadzadeh Kosari, Leonard Wartofsky and Seyed Rasoul Zakavi
    Citation: BMC Endocrine Disorders 2021 21:221
  18. Primary hyperparathyroidism (PHPT) and familial hypocalciuric hypercalcemia (FHH) are the most important differential diagnosis of parathyroid hormone (PTH)-dependent hypercalcemia. The clinical features of FH...

    Authors: Maryam Zahedi, Reyhane Hizomi Arani, Maryam Rafati, Atieh Amouzegar and Farzad Hadaegh
    Citation: BMC Endocrine Disorders 2021 21:220
  19. Accumulating evidence indicates that vitamin D deficiency has been increased globally over the last two decades. However, the majority of these studies are concerned with cities and there is scant information ...

    Authors: Maryam Marzban, Mohammadreza Kalantarhormozi, Mehdi Mahmudpour, Afshin Ostovar, Saeed Keshmiri, Amir Hossein Darabi, Abdolmohammad Khajeian, Amirreza Bolkheir, Azam Amini and Iraj Nabipour
    Citation: BMC Endocrine Disorders 2021 21:219
  20. The study aimed to evaluate whether the presence of DKA at diabetes diagnosis was associated with poorer metabolic control during a 5-year follow-up.

    Authors: Kowalczyk Emilia, Stypułkowska Aneta, Majewska Barbara, Jarzębowska Małgorzata, Hoffmann Aleksandra, Buła Paulina and Szypowska Agnieszka
    Citation: BMC Endocrine Disorders 2021 21:218
  21. Pituitary carcinomas (PCs), defined as distant metastases of pituitary neoplasms, are very rare malignancies. Because the clinical presentation of PCs is variable, early diagnosis and management remain challen...

    Authors: Congxin Dai, Bowen Sun, Shusen Guan, Wei Wang, Honggang Liu, Yong Li, Jialiang Zhang and Jun Kang
    Citation: BMC Endocrine Disorders 2021 21:217
  22. Aging reduces the quality and strength of bones and muscles and increases body fat, which can lead to the simultaneous occurrence of sarcopenia, osteopenia, and adiposity, a condition referred to as OsteoSarco...

    Authors: Yu-Hsiang Su, Yu-Ming Chang, Chih-Ying Kung, Chiu-Kuei Sung, Wei-Shin Foo, Mei-Hua Wu and Shang-Jyh Chiou
    Citation: BMC Endocrine Disorders 2021 21:216
  23. This study aimed to investigate the differences in oxidative stress (OS) levels represented by 8-iso-prostaglandin F (8-iso-PGF) and analyze its correlation with the intra-abdominal fat (IAF) area and the gly...

    Authors: Ning Ma, Yujian Zhang, Binbin Liu, Xiaojiao Jia, Rui Wang and Qiang Lu
    Citation: BMC Endocrine Disorders 2021 21:215
  24. Contiguous gene deletion syndromes are rare genomic disorders caused by deletion of large segments of DNA resulting in co-occurrence of apparently unrelated multiple clinical phenotypes. We report a boy with c...

    Authors: Asanka Rathnasiri, Udara Senarathne, Visvalingam Arunath, Thabitha Hoole, Ishara Kumarasiri, Oshanie Muthukumarana, Eresha Jasinge and Sachith Mettananda
    Citation: BMC Endocrine Disorders 2021 21:214
  25. Thyroid crisis is a life-threatening condition in thyrotoxic patients. Although differentiated thyroid cancer is one of the causes of hyperthyroidism, reports on thyroid crisis caused by thyroid cancer are qui...

    Authors: Kai Takedani, Masakazu Notsu, Naoko Adachi, Sayuri Tanaka, Masahiro Yamamoto, Mika Yamauchi, Naotake Yamauchi, Riruke Maruyama and Keizo Kanasaki
    Citation: BMC Endocrine Disorders 2021 21:213
  26. Hypothyroidism is frequent and has various forms of muscle involvement. We report the diagnosis and treatment of a case of rhabdomyolysis, bilateral osteofascial compartment syndrome (OCS) of the lower extremi...

    Authors: Lijue Ren, Cuiying Wei, Feng Wei, Ruiting Ma, Yan Liu, Yonghong Zhang, Wei Wang, Jing Du, Lin Bai, Yexia Xue and Shaohua Cui
    Citation: BMC Endocrine Disorders 2021 21:212
  27. Impaired fasting glucose (IFG) is a prediabetic condition. Considering that the clinical symptoms of IFG are inconspicuous, these tend to be easily ignored by individuals, leading to conversion to diabetes mel...

    Authors: Yuqi Wang, Liangxu Wang, Yanli Su, Li Zhong and Bin Peng
    Citation: BMC Endocrine Disorders 2021 21:211
  28. Previous studies have shown that bipolar disorder is closely related to thyroid dysfunction. Psychiatric drugs have a large or small effect on thyroid function, and thyroid hormone levels can also affect the e...

    Authors: Shengnan Zhao, Xu Zhang, Yaling Zhou, Hao Xu, Yuwei Li, Yuexin Chen, Bo Zhang and Xueli Sun
    Citation: BMC Endocrine Disorders 2021 21:210
  29. There are many conflicting opinions regarding the association between anemia and diabetes mellitus (DM), and the mechanism by which DM influences anemia remains uncertain. Therefore, we aimed to investigate th...

    Authors: Mihye Kim, Sook-Hyun Lee, Kyoung Sun Park, Eun-Jung Kim, Sujung Yeo and In-Hyuk Ha
    Citation: BMC Endocrine Disorders 2021 21:209
  30. To assess the gaps between the initial management of patients with differentiated thyroid cancer (DTC) in real clinical practice and the recommendations of the 2012 Chinese DTC guidelines.

    Authors: Jie Ming, Jing-Qiang Zhu, Hao Zhang, Hui Sun, Jun Wang, Ruo-Chuan Cheng, Lei Xie, Xing-Rui Li, Wen Tian and Tao Huang
    Citation: BMC Endocrine Disorders 2021 21:208
  31. exposure to iodinated contrast media (ICM) can cause hyperthyroidism, due to disruption of thyroid hormone regulation. Although rare, it can have severe consequences and can lead to fatal complications. Curren...

    Authors: Sofie M. Diepenbroek, A. de Jonghe, C. van Rees and E. Seebus
    Citation: BMC Endocrine Disorders 2021 21:207
  32. Evidence of possible beneficial effects of dietary diabetes risk reduction score (DDRRS) on reducing the risk of various chronic diseases such as metabolic syndrome (MetS) are limited. This is a prospective, p...

    Authors: Parvin Mirmiran, Hossein Farhadnejad, Farshad Teymoori, Golaleh Asghari, Karim Parastouei and Fereidoun Azizi
    Citation: BMC Endocrine Disorders 2021 21:206
  33. Atrial natriuretic peptide (ANP) is a cardiovascular and metabolic hormone that has been identified recently as being associated with chronic kidney disease (CKD) without diabetes. Cytokines such as interleuki...

    Authors: Chenxiao Liu, Qi Li, Xiu Feng, Jian Zhu and Qian Li
    Citation: BMC Endocrine Disorders 2021 21:204
  34. Maturity Onset Diabetes of the Young (MODY) is a monogenic, autosomal, dominant disease that results in beta-cells dysfunction with consequent hyperglycaemia. It represents a rare form of diabetes (1–2% of all...

    Authors: Lucia Brodosi, Bianca Baracco, Vilma Mantovani and Loris Pironi
    Citation: BMC Endocrine Disorders 2021 21:202
  35. The relationship between dyslipidemia and obesity has been widely reported, but the global lipid profiles associated with the development of obesity still need to be clarified. An investigation into the associ...

    Authors: Ruili Yin, Xiaojing Wang, Kun Li, Ke Yu and Longyan Yang
    Citation: BMC Endocrine Disorders 2021 21:201
  36. We aimed to assess the comparative efficiency and safety of the use of glyburide, metformin, and insulin in gestational diabetes mellitus (GDM).

    Authors: Dan-Qing Yu, Guan-Xin Xu, Xin-Yuan Teng, Jing-Wei Xu, Liang-Fang Tang, Chun Feng, Jin-Peng Rao, Min Jin and Li-Quan Wang
    Citation: BMC Endocrine Disorders 2021 21:199
  37. The incidence rate of diabetes is increasing year by year, seriously threatening human health. As a predictor of glycemic control, glycated hemoglobin is reported to be related to various complications and pro...

    Authors: Rui Huang, Li Yan and Yuhua Lei
    Citation: BMC Endocrine Disorders 2021 21:198
  38. Macroprolactin is responsible for pseudohyperprolactinemia and is a common pitfall of the prolactin immunoassay. We aimed to determine the frequency of macroprolactinemia in Chinese hyperprolactinemic patients...

    Authors: Yao Hu, Jiajin Ni, Buyue Zhang, Wei Cheng, Huating Zhang, Hongying Ye, Lijin Ji, Bin Lu and Ming Guan
    Citation: BMC Endocrine Disorders 2021 21:197
  39. Previous studies have shown that the minor allele (C allele) for Cry 1 rs2287161, may be associated with increased risk of cardiovascular diseases (CVDs). Low resting metabolic rate (RMR) caused by the diet ha...

    Authors: Atieh Mirzababaei, Elnaz Daneshzad, Farideh Shiraseb, Sanaz Pourreza, Leila Setayesh, Cain C. T. Clark, Hadith Tangestani, Faezeh Abaj, Habib Yarizadeh and Khadijeh Mirzaei
    Citation: BMC Endocrine Disorders 2021 21:196
  40. The serine protease inhibitor-1 (SERPINE1) rs1799889 single nucleotide polymorphism (SNP) has been constantly associated with diabetes mellitus (DM) and its vascular complications. The aim of this meta-analysi...

    Authors: JingYi Chen, ChuanNan Zhai, ZhiQian Wang, Rui Li, WenJing Wu, Kai Hou, Mohammad Alzogool, Yan Wang and HongLiang Cong
    Citation: BMC Endocrine Disorders 2021 21:195
  41. Variants of chromodomain helicase DNA binding protein 7 (CHD7) gene are commonly associated with Kallmann syndrome (KS) and account for 5–6% of idiopathic hypogonadotropic hypogonadism (IHH) cases. Here we rep...

    Authors: Weiwei Xu, Weibin Zhou, Haiyang Lin, Dan Ye, Guoping Chen, Fengqin Dong and Jianguo Shen
    Citation: BMC Endocrine Disorders 2021 21:193
  42. The association between the Mediterranean diet (MED) or dietary approach to stop hypertension (DASH) and cardiovascular disease (CVD) risk factors is well-documented. Nevertheless, a consistent relationship wi...

    Authors: Monireh Panbehkar-Jouybari, Mehdi Mollahosseini, Amin Salehi-Abargouei, Hossein Fallahzadeh, Masoud Mirzaei and Mahdieh Hosseinzadeh
    Citation: BMC Endocrine Disorders 2021 21:192
  43. Nivolumab is an anti-programmed cell death protein 1 antibody, typically used as cancer immunotherapy agent. Despite multiple clinical benefits it might cause autoimmune-related side-effects, often involving t...

    Authors: Sofia Antoniou, Georgios Bazazo, Ludwig Röckl, Marios Papadakis and Christian Berg
    Citation: BMC Endocrine Disorders 2021 21:191
  44. The long-term association between physical activity and endothelial function has not previously been investigated in patients with type 2 diabetes. Therefore, we aimed to evaluate the relationship between phys...

    Authors: Jonathan Mathias Baier, Kristian Løkke Funck, Liv Vernstrøm, Esben Laugesen and Per Løgstrup Poulsen
    Citation: BMC Endocrine Disorders 2021 21:189

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