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  1. Weight loss therapy is becoming more and more important, and two classes of molecules, namely amylin receptor and GLP-1 receptor agonists, have shown promise in this regard. Interestingly, these molecules have...

    Authors: Anna Thorsø Larsen, Sofie Gydesen, Nina Sonne, Morten Asser Karsdal and Kim Henriksen
    Citation: BMC Endocrine Disorders 2021 21:10
  2. Neuroendocrine tumor (NET) with adrenocorticotropic hormone (ACTH) secretion are very rare. To our knowledge, no follow-up study is published for ACTH-secreting NET, regardless of the primary site, to show sec...

    Authors: Fatemeh Rahmani, Maryam Tohidi, Maryam Dehghani, Behrooz Broumand and Farzad Hadaegh
    Citation: BMC Endocrine Disorders 2021 21:9
  3. Studies analyzing the association between parity and normal-weight metabolic syndrome (MetS) in postmenopausal women of normal weight remain limited, this study aimed to explore the association between parity ...

    Authors: Mengte Shi, Xinhe Zhou, Chao Zheng and Youjin Pan
    Citation: BMC Endocrine Disorders 2021 21:8
  4. Red cell distribution width (RDW) is a predicter of infections, cancer and diabetes. However, the relationship between RDW and β-cell function and insulin resistance remains unclear in patients with type 2 dia...

    Authors: Deyuan Zhang, Siqi Zhang, Lifang Wang, Tianrong Pan and Xing Zhong
    Citation: BMC Endocrine Disorders 2021 21:7
  5. Multiple pathological manifestations are rarely present in patients with primary hyperparathyroidism (PHPT). Here we described a case of a young woman who presented with multiple skeletal destructions and rece...

    Authors: Shuai Lu, Maoqi Gong, Yejun Zha, Aimin Cui, Wei Tian and Xieyuan Jiang
    Citation: BMC Endocrine Disorders 2021 21:5
  6. Noonan syndrome is an inherited disease involving multiple systems. More than 15 related genes have been discovered, among which LZTR1 was discovered recently. However, the pathogenesis and inheritance pattern of...

    Authors: Xiu Zhao, Zhuoguang Li, Li Wang, Zhangzhang Lan, Feifei Lin, Wenyong Zhang and Zhe Su
    Citation: BMC Endocrine Disorders 2021 21:2
  7. Serum uric acid (SUA) is associated with the development of diabetic kidney disease (DKD). Thyroid hormones can regulate metabolism and insulin resistance. The relationship between SUA and thyroid function in ...

    Authors: Xiaomeng Feng, Jing Huang, Yan Peng and Yuan Xu
    Citation: BMC Endocrine Disorders 2021 21:1
  8. Thyroid associated orbitopathy (TAO) is the most common extrathyroidal complication of Graves’ disease. The disease course ranges from mild, where symptomatic therapy is sufficient, to severe, where high dose ...

    Authors: Janos K. Aranyosi, Tamas Deli, Annamaria Erdei, Geza Toth, Attila Jakab, Mariann Fodor, Endre V. Nagy and Bernadett Ujhelyi
    Citation: BMC Endocrine Disorders 2020 20:183
  9. Diabetic ketoacidosis (DKA) and hyperosmolar hyperglycemic state (HHS) are the two most common hyperglycemic emergencies (HEs) associated with diabetes mellitus. Individuals with HEs can present with combined ...

    Authors: Xiao-yan Wu, Dun-min She, Fang Wang, Gang Guo, Ran Li, Ping Fang, Ling Li, Yun Zhou, Ke-qin Zhang and Ying Xue
    Citation: BMC Endocrine Disorders 2020 20:182
  10. To evaluate the association between diet and disease, the consideration of a whole diet has appeared to be more effective than the examination of single-nutrient intake. This study aimed to examine the relatio...

    Authors: Sahar Golpour-Hamedani, Nahid Rafie, Makan Pourmasoumi, Parvane Saneei and Sayyed Morteza Safavi
    Citation: BMC Endocrine Disorders 2020 20:181
  11. Existing prevention and treatment strategies target the classic types of diabetes yet this approach might not always be appropriate in some settings where atypical phenotypes exist. This study aims to assess t...

    Authors: Charlotte M. Bavuma, Sanctus Musafiri, Pierre-Claver Rutayisire, Loise M. Ng’ang’a, Ruth McQuillan and Sarah H. Wild
    Citation: BMC Endocrine Disorders 2020 20:180
  12. Lipid accumulation product (LAP) is a new index based on a combination of waist circumference (WC) and serum triglycerides (TG) reflecting lipid accumulation. In this cross-sectional study, we aimed to explore...

    Authors: Lianqin Dong, Mingzhu Lin, Wengui Wang, Danyan Ma, Yun Chen, Weijuan Su, Zheng Chen, Shunhua Wang, Xuejun Li, Zhibin Li and Changqin Liu
    Citation: BMC Endocrine Disorders 2020 20:179
  13. Circulating angiopoietin-like 2 (ANGPTL2) protein levels are known to be significantly increased in numerous chronic inflammatory diseases and are associated with the diagnosis and/or prognosis of cardiovascular ...

    Authors: Yan Wang, Zhaohui Zheng, Yuxian Yang, Jianan Lang, Ning Zhang, Longyan Yang and Dong Zhao
    Citation: BMC Endocrine Disorders 2020 20:178
  14. Plasma aldosterone-to-renin ratio (ARR) is popularly used for screening primary aldosteronism (PA). Some medications, including diuretics, are known to have an effect on ARR and cause false-negative and false-...

    Authors: Toshitaka Sawamura, Shigehiro Karashima, Satoshi Nagase, Hidetaka Nambo, Eiko Shimizu, Takuya Higashitani, Daisuke Aono, Azusa Ohbatake, Mitsuhiro Kometani, Masashi Demura, Kenji Furukawa, Yoshiyu Takeda and Takashi Yoneda
    Citation: BMC Endocrine Disorders 2020 20:177
  15. Thyroid associated orbitopathy (TAO) is defined as an immune mediated inflammatory process affecting the extraocular muscles, connective and adipose tissue of uncertain etiopathogenesis. TAO are classically de...

    Authors: Radwan El Othman, Christelle Ephrem, Elsie Touma, Souheil Hallit and Rola El Othman
    Citation: BMC Endocrine Disorders 2020 20:176
  16. Approximately 60% of adrenocortical carcinomas (ACC) are functional, and Cushing’s syndrome is the most frequent diagnosis that has been revealed to have a particularly poor prognosis. Since 30% of ACC present...

    Authors: Sawako Suzuki, Tomoki Minamidate, Akina Shiga, Yutarou Ruike, Kazuki Ishiwata, Kumiko Naito, Akiko Ishida, Hanna Deguchi, Masanori Fujimoto, Hisashi Koide, Ichiro Tatsuno, Jun-ichiro Ikeda, Yuto Yamazaki, Hironobu Sasano and Koutaro Yokote
    Citation: BMC Endocrine Disorders 2020 20:173
  17. Microalbuminuria is a prognostic marker of diabetes kidney disease. It is generally diagnosed as the ratio of urinary albumin to creatinine (UACR) of 30-300 mg/g. Hashimoto’s thyroiditis is a common disease in...

    Authors: Wei Zhu, Xuejie Dong, Qingrong Pan, Yanjin Hu and Guang Wang
    Citation: BMC Endocrine Disorders 2020 20:172
  18. Individuals with normal weight obesity (NWO) are predisposed to having cardiometabolic disorders. This study aims to investigate the circulating levels of vaspin, leptin and their association with glycemic and...

    Authors: Ehsaneh Taheri, Saeed Hosseini, Mostafa Qorbani and Parvin Mirmiran
    Citation: BMC Endocrine Disorders 2020 20:171
  19. Recent study showed that individuals with type 2 diabetes have a high risk of developing colorectal cancer (CRC), in which Receptor for Advanced Glycation End Products (RAGE) plays a pivotal role. We conducted...

    Authors: Xiaohai Zhou, Ning Lin, Mingjie Zhang, Xiaoling Wang, Ye An, Qing Su, Peng Du, Bo Li and Hanbei Chen
    Citation: BMC Endocrine Disorders 2020 20:170
  20. Metabolic syndrome (MetS) is a major public health concern due to its high prevalence and association with heart disease and diabetes. Artificial neural networks (ANN) are emerging as a reliable means of model...

    Authors: Meysam Eyvazlou, Mahdi Hosseinpouri, Hamidreza Mokarami, Vahid Gharibi, Mehdi Jahangiri, Rosanna Cousins, Hossein-Ali Nikbakht and Abdullah Barkhordari
    Citation: BMC Endocrine Disorders 2020 20:169
  21. While obesity and overweight status are firmly established risk factors for Type 2 diabetes mellitus (T2DM), a substantial proportion of diabetic individuals, especially in Africa and Asia, are often underweig...

    Authors: Anuradha Rajamanickam, Saravanan Munisankar, Chandra Kumar Dolla, Kannan Thiruvengadam and Subash Babu
    Citation: BMC Endocrine Disorders 2020 20:168
  22. Despite the current debate about the effects of high intensity interval training (HIIT), HIIT elicits big morpho-physiological benefit on Metabolic Syndrome (MetS) treatment. However, no review or meta-analysi...

    Authors: I. Serrablo-Torrejon, A. Lopez-Valenciano, M. Ayuso, E. Horton, X. Mayo, G. Medina-Gomez, G. Liguori and A. Jimenez
    Citation: BMC Endocrine Disorders 2020 20:167
  23. Prader-Willi syndrome (PWS) is a multisymptomatic, rare, genetic, neurodevelopmental disorder in adults mainly characterized by hyperphagia, cognitive dysfunction, behavioral problems and risk of morbid obesit...

    Authors: Hasanain Hamid Shukur, Yolanda B. de Rijke, Elisabeth F. C. van Rossum, Laith Hussain-Alkhateeb and Charlotte Höybye
    Citation: BMC Endocrine Disorders 2020 20:166
  24. Congenital adrenal hyperplasia (CAH) is an autosomal recessive group of diseases. 21-Hydroxylase deficiency (21OHD) accounts for between 95 and 99% of all CAH cases.

    Authors: Tania Mayvel Espinosa Reyes, Teresa Collazo Mesa, Paulina Arasely Lantigua Cruz, Adriana Agramonte Machado, Emma Domínguez Alonso and Henrik Falhammar
    Citation: BMC Endocrine Disorders 2020 20:165
  25. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Elske L. van den Burg, Marjolein P. Schoonakker, Petra G. van Peet, M. Elske. van den Akker-van Marle, Ko Willems van Dijk, Valter D. Longo, Hildo J. Lamb, Mattijs E. Numans and Hanno Pijl
    Citation: BMC Endocrine Disorders 2020 20:164

    The original article was published in BMC Endocrine Disorders 2020 20:94

  26. Primary nasopharyngeal lymphoma (NPL) is a very rare tumor of Waldeyer ring (WR) lymphoid tissue. It is challenging to differentiate lymphoma infiltration of pituitary from a pituitary adenoma, meningioma infi...

    Authors: Maryam Zahedi, Reyhane Hizomi Arani, Maryam Tohidi, Shirin Haghighi, Masoud Mehrpour and Farzad Hadaegh
    Citation: BMC Endocrine Disorders 2020 20:163
  27. Vitamin D deficiency is diagnosed by total serum 25-hydroxyvitamin D (25(OH)D) concentration and is associated with poor health and increased mortality; however, some populations have low 25(OH) D concentratio...

    Authors: Lina H. M. Ahmed, Alexandra E. Butler, Soha R. Dargham, Aishah Latif, Omar M. Chidiac, Stephen L. Atkin and Charbel Abi Khalil
    Citation: BMC Endocrine Disorders 2020 20:161
  28. Dietary fatty acids are important dietary determinants of metabolic disorders in human. However, it is important to develop an index that considers not only the amount of dietary fatty acids but also the struc...

    Authors: Nika Soltani, Mahdieh Abbasalizad Farhangi, Leila Nikniaz and Mahsa Mahmoudinezhad
    Citation: BMC Endocrine Disorders 2020 20:159
  29. A growing body of evidence supports neutrophils as having an active role in the development of diabetic kidney disease (DKD). However, the clinical relevance of neutrophils and DKD in autoimmune diabetes remai...

    Authors: Yao Yu, Qiuqiu Lin, Dewei Ye, Yanfei Wang, Binbin He, Yanhua Li, Gan Huang, Zhiguang Zhou and Yang Xiao
    Citation: BMC Endocrine Disorders 2020 20:158
  30. Follow-up care provided via telemedicine (TM) is intended to be a more integrated care pathway to manage diabetes-related foot ulcers (DFU) than traditionally-delivered healthcare. However, knowledge of the ef...

    Authors: Marjolein M. Iversen, Jannicke Igland, Hilde Smith-Strøm, Truls Østbye, Grethe S. Tell, Svein Skeie, John G. Cooper, Mark Peyrot and Marit Graue
    Citation: BMC Endocrine Disorders 2020 20:157
  31. Previous studies have suggested that patients with diabetes mellitus (DM) have higher prevalence of atherosclerotic cardiovascular disease (ASCVD), and plasma levels of free fatty acids (FFAs) are a useful mar...

    Authors: Ming-Hua Zhang, Ye-Xuan Cao, Li-Guo Wu, Na Guo, Bing-Jie Hou, Li-Jing Sun, Yuan-Lin Guo, Na-Qiong Wu, Qian Dong and Jian-Jun Li
    Citation: BMC Endocrine Disorders 2020 20:156
  32. Detailed description of hyperglycemia management in diabetic patients infected with SARS-CoV-2 remain limited, although patients with diabetes show higher complication and mortality rate than patients without ...

    Authors: François R. Jornayvaz, Benjamin Assouline, Jérôme Pugin and Karim Gariani
    Citation: BMC Endocrine Disorders 2020 20:155
  33. Glucocorticoid therapy is the most common cause of iatrogenic osteoporosis. Less is known regarding the effect of glucocorticoids when used as replacement therapy on bone remodelling in patients with adrenal i...

    Authors: Rosemary Dineen, Lucy-Ann Behan, Grainne Kelleher, Mark J. Hannon, Jennifer J. Brady, Bairbre Rogers, Brian G. Keevil, William Tormey, Diarmuid Smith, Christopher J. Thompson, Malachi J. McKenna, Wiebke Arlt, Paul M. Stewart, Amar Agha and Mark Sherlock
    Citation: BMC Endocrine Disorders 2020 20:154
  34. The objectives of this study were to estimate the prevalence of microalbuminuria and examine the association of microalbuminuria with metabolic syndrome (MetS) and its component in a Bangladeshi adult cohort.

    Authors: Muntakim Mahmud Saadi, Manindra Nath Roy, Rubena Haque, Farida Akhter Tania, Shakil Mahmood and Nurshad Ali
    Citation: BMC Endocrine Disorders 2020 20:153
  35. Metabolic inflammation is an essential event in obesity-induced diabetes and insulin resistance. In obesity, an increasing number of macrophages recruited into visceral adipose tissues undergo significant M1-like...

    Authors: Chaolong Liu, Yanting Yuan, Ji Zhou, Ruixin Hu, Lixia Ji and Guohui Jiang
    Citation: BMC Endocrine Disorders 2020 20:152
  36. Low dose naltrexone (LDN) is reported to have beneficial effects in several autoimmune diseases. The purpose of this study was to examine whether starting LDN was followed by changes in the dispensing of thyro...

    Authors: Guttorm Raknes and Lars Småbrekke
    Citation: BMC Endocrine Disorders 2020 20:151
  37. Despite the evidence available on the adverse impact of gestational diabetes (GDM) and thyroid disorders on developing type 2 diabetes (T2DM), the concurrent influence of these disorders on the incidence of T2...

    Authors: Maryam Zahedi, Elham Kazemian, Fahimeh Ramezani-Tehrani, Maryam Tohidi, Fereidoun Azizi, Davood Khalili, Maryam Rahmati and Atieh Amouzegar
    Citation: BMC Endocrine Disorders 2020 20:150
  38. A high-molecular-weight form of insulin-like growth factor-2 (IGF-2), known as “big” IGF-2, is occasionally produced by various tumor types, leading to hypoglycemia. Although solitary fibrous tumor (SFT) is a ...

    Authors: Keizo Kaneko, Shojiro Sawada, Chihiro Satake, Keiichi Kondo, Tomohito Izumi, Mamiko Tanaka, Junta Imai, Tetsuya Yamada, Hiroki Katsushima, Fumiyoshi Fujishima and Hideki Katagiri
    Citation: BMC Endocrine Disorders 2020 20:148
  39. Worldwide, the epidemiological and demographic transitions have resulted in nutrition shift characterized by an increased consumption of high energy fast food products. In just over 3 decades, overweight and o...

    Authors: Pedro Pallangyo, Zabella S. Mkojera, Naairah R. Hemed, Happiness J. Swai, Nsajigwa Misidai, Lucy Mgopa, Smita Bhalia, Jalack Millinga, Theophil L. Mushi, Lucia Kabeya, Aisha Omar, Alice Kaijage, Rydiness Mulashani, Silvia Mosha, Faustina Mwapinga and Mohamed Janabi
    Citation: BMC Endocrine Disorders 2020 20:147
  40. The risk of surgical site infection has been reported to be higher in patients with poorly controlled diabetes. Since chronic hyperglycemia impairs neutrophil functions, preoperative glycemic control may resto...

    Authors: Daichi Fujimoto, Yuki Nomura, Moritoki Egi, Norihiko Obata and Satoshi Mizobuchi
    Citation: BMC Endocrine Disorders 2020 20:146
  41. This study tested the association between serum levels of microRNA-486, −146b and -15b and betatrophin in normal and obese children with/without type 2 diabetes mellitus (T2DM).

    Authors: Khalid M. Mohany, Osamah Al rugaie, Osama Al-wutayd, Abdullah Al-Nafeesah and Tahia H. Saleem
    Citation: BMC Endocrine Disorders 2020 20:145
  42. Congenital adrenal hyperplasia (CAH) with 17α-hydroxylase deficiency is a rare disease; patients often require lifetime cortisol treatment. In this case report, we presented a patient with CAH and 17α-hydroxyl...

    Authors: Chenyu Xiang, Minmin Han, Yi Zhang, Jianhong Yin, Li’e Pei, Jing Yang and Yunfeng Liu
    Citation: BMC Endocrine Disorders 2020 20:144
  43. Previous studies have shown inconsistent results about the usefulness of bilateral inferior petrosal sinus sampling (BIPSS) in differential diagnosis of adrenocorticotropic hormone (ACTH)-dependent Cushing syn...

    Authors: Hao Wang, Ying Ba, Qian Xing and Run-Ce Cai
    Citation: BMC Endocrine Disorders 2020 20:143
  44. Primary Empty Sella (PES) syndrome is an increasingly common disorder, mostly diagnosed as an incidental finding during brain imaging scans. We intended to review the clinical management and hormonal profile o...

    Authors: Aishah A. Ekhzaimy, Muhammad Mujammami, Shabana Tharkar, Manahel A. Alansary and Daad Al Otaibi
    Citation: BMC Endocrine Disorders 2020 20:142
  45. Studies have shown that the response of bone mineral density (BMD) to parathyroidectomy for symptomatic primary hyperparathyroidism (PHPT) is heterogeneous and difficult to predict. However, the independent fa...

    Authors: Shuai Lu, Maoqi Gong, Yejun Zha, Aimin Cui, Chen Chen, Weitong Sun, Kehan Hua, Wei Tian and Xieyuan Jiang
    Citation: BMC Endocrine Disorders 2020 20:141

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