Skip to main content



Page 3 of 15

  1. Content type: Research article

    Soluble receptor for advanced glycation end-products (sRAGE) and advanced glycation end-products (AGE) have been associated with risks of cardiovascular disease. Because sRAGE is regarded as a scavenger to AGE...

    Authors: Kuang-Hsing Chiang, Jaw-Wen Chen, Shao-Sung Huang, Hsin-Bang Leu, Shing-Jong Lin and Po-Hsun Huang

    Citation: BMC Endocrine Disorders 2018 18:84

    Published on:

  2. Content type: Case report

    Mucopolysaccharidosis type I (MPS I) results in significant disease burden and early treatment is important for optimal outcomes. Recognition of short stature and growth failure as symptoms of MPS I among pedi...

    Authors: Ana Maria Martins, Kristin Lindstrom, Sandra Obikawa Kyosen, Maria Veronica Munoz-Rojas, Nathan Thibault and Lynda E. Polgreen

    Citation: BMC Endocrine Disorders 2018 18:83

    Published on:

  3. Content type: Case report

    Gitelman syndrome (GS) is an inherited autosomal recessive renal tubular disorder characterized by low levels of potassium and magnesium in the blood, decreased excretion of calcium in the urine, and elevated ...

    Authors: Haiyang Zhou, Xinhuan Liang, Yingfen Qing, Bihui Meng, Jia Zhou, Song Huang, Shurong Lu, Zhenxing Huang, Haiyan Yang, Yan Ma and Zuojie Luo

    Citation: BMC Endocrine Disorders 2018 18:82

    Published on:

  4. Content type: Research article

    Proinsulin connecting peptide (C-Peptide) is a marker of the beta-cell function and has been considered a marker of insulin resistance whose evidence suggests were associated with cardiovascular mortality. Our...

    Authors: Romildo Luiz Monteiro Andrade, Denise P. Gigante, Isabel Oliveira de Oliveira and Bernardo Lessa Horta

    Citation: BMC Endocrine Disorders 2018 18:80

    Published on:

  5. Content type: Research article

    Poor understanding of diabetes management targets is associated with worse disease outcomes. Patients may use different information than providers to assess their diabetes control. In this study, we identify t...

    Authors: Anjali Gopalan, Katherine Kellom, Kevin McDonough and Marilyn M. Schapira

    Citation: BMC Endocrine Disorders 2018 18:79

    Published on:

  6. Content type: Case report

    Congenital lipoid adrenal hyperplasia (CLAH) is an extremely rare and the most severe form of congenital adrenal hyperplasia. Typical features include disorder of sex development, early-onset adrenal crisis an...

    Authors: Xiu Zhao, Zhe Su, Xia Liu, Jianming Song, Yungen Gan, Pengqiang Wen, Shoulin Li, Li Wang and Lili Pan

    Citation: BMC Endocrine Disorders 2018 18:78

    Published on:

  7. Content type: Research article

    Type 2 diabetes mellitus has become one of the most important public health concerns worldwide. Due to its high prevalence and morbidity, there is an avid necessity to find new therapies that slow the progress...

    Authors: Miguel Ángel Gómez-Sámano, Jorge Enrique Baquerizo-Burgos, Melissa Fabiola Coronel Coronel, Buileng Daniela Wong-Campoverde, Fernando Villanueva-Martinez, Diego Molina-Botello, Jose Alonso Avila-Rojo, Lucía Palacios-Báez, Daniel Cuevas-Ramos, Francisco Javier Gomez-Perez, Alejandro Zentella-Dehesa, Álvaro Aguayo-González and Alfonso Gulias-Herrero

    Citation: BMC Endocrine Disorders 2018 18:77

    Published on:

  8. Content type: Research article

    Hashimoto’s thyroiditis is a complex autoimmune thyroid disease, the onset of which is associated with environmental exposures and specific susceptibility genes. Its incidence in females is higher than its inc...

    Authors: Licheng Gong, Beihong Liu, Jing Wang, Hong Pan, Anhui Qi, Siyang Zhang, Jinyi Wu, Ping Yang and Binbin Wang

    Citation: BMC Endocrine Disorders 2018 18:76

    Published on:

  9. Content type: Research article

    Improved glycemic control is the desired outcome after the discharge of patients with diabetes. We aimed to determine the efficacy of a basal-bolus insulin protocol in hospitalized patients with diabetes treat...

    Authors: Elena Chertok Shacham, Hila Kfir, Naama Schwartz and Avraham Ishay

    Citation: BMC Endocrine Disorders 2018 18:75

    Published on:

  10. Content type: Study protocol

    Health care providers aim to stimulate self-management in type 2 diabetes (T2DM) patients. However, they have a limited number of patient contacts to do this. With the growing number of T2DM patients, innovati...

    Authors: Anne Meike Boels, Guy Rutten, Nicolaas Zuithoff, Ardine de Wit and Rimke Vos

    Citation: BMC Endocrine Disorders 2018 18:74

    Published on:

  11. Content type: Study protocol

    Little evidence exists on the impact of diabetes risk scores, e.g. on physicians and patient’s behavior, perceived risk of persons, shared-decision making and particularly on patient’s health. The aim of this ...

    Authors: Esther Jacobs, Miguel Tamayo, Joachim Rosenbauer, Matthias B. Schulze, Oliver Kuss and Wolfgang Rathmann

    Citation: BMC Endocrine Disorders 2018 18:72

    Published on:

  12. Content type: Research article

    When children with type 1 diabetes approach adolescence, they are encouraged to become more involved in diabetes self-management. This study explored the challenges pre-adolescent children encounter when self-...

    Authors: David Rankin, Jeni Harden, Katharine Barnard, Louise Bath, Kathryn Noyes, John Stephen and Julia Lawton

    Citation: BMC Endocrine Disorders 2018 18:71

    Published on:

  13. Content type: Research article

    Vitamin D has been known since the twentieth Century for its benefits in bone health. Recent observational studies have demonstrated its benefits in infectious diseases such as tuberculosis and non-communicabl...

    Authors: Elizabeth Kagotho, Geoffrey Omuse, Nancy Okinda and Peter Ojwang

    Citation: BMC Endocrine Disorders 2018 18:70

    Published on:

  14. Content type: Research article

    This study aimed to examine the switch from glargine+once daily insulin aspart (1 + 1 regimen) to glargine+insulin aspart 30 before breakfast combined with exercise and in patients with type 2 diabetes mellitu...

    Authors: Jing Li, Liming Wang, Fen Chen, Dongxia Xia and Lingling Miao

    Citation: BMC Endocrine Disorders 2018 18:69

    Published on:

  15. Content type: Case report

    Congenital adrenal hyperplasia (CAH) resulting from steroid 11β-hydroxylase deficiency (11β-OHD) is caused by mutations in the CYP11B1 gene. It is the second major form of CAH associated with hypertension and hyp...

    Authors: Xianxian Yuan, Lin Lu, Shi Chen, Jun Jiang, Xiangqing Wang, Zhihui Liu, Huijuan Zhu, Hui Pan and Zhaolin Lu

    Citation: BMC Endocrine Disorders 2018 18:68

    Published on:

  16. Content type: Study protocol

    Subclinical hypothyroidism is common in older people and its contribution to health and disease needs to be elucidated further. Observational and clinical trial data on the clinical effects of subclinical hypo...

    Authors: R. S. Du Puy, I. Postmus, D. J. Stott, M. R. Blum, R. K. E. Poortvliet, W. P. J. Den Elzen, R. P. Peeters, B. C. van Munster, B. H. R. Wolffenbuttel, R. G. J. Westendorp, P. M. Kearney, I. Ford, S. Kean, C. M. Messow, T. Watt, J. W. Jukema…

    Citation: BMC Endocrine Disorders 2018 18:67

    Published on:

  17. Content type: Research article

    Insulin and insulin-like growth factor (IGF)-1 coupled with growth hormone helps control timing of sexual maturation. Mutations and variants in multiple genes are associated with development or reduced risk of...

    Authors: Hua-Pin Chang, Shun-Fa Yang, Shu-Li Wang and Pen-Hua Su

    Citation: BMC Endocrine Disorders 2018 18:66

    Published on:

  18. Content type: Research article

    Metabolic syndrome (MetS) includes obesity, diabetes, dyslipidemia and hypertension. Its incidence is rapidly increasing worldwide, particularly in postmenopausal women. Estrogens regulate glucose homeostasis ...

    Authors: Lingxia Zhao, Xuemei Fan, Lin Zuo, Qiang Guo, Xiaole Su, Guangxia Xi, Ziyan Zhang, Jianlin Zhang and Guoping Zheng

    Citation: BMC Endocrine Disorders 2018 18:65

    Published on:

  19. Content type: Research article

    To investigate the effect of a mildly elevated thyroid-stimulating hormone (TSH) concentration between 2.5 and 4.0 mIU/L during the first trimester on pregnancy outcomes in thyroid peroxydase antibody (TPOAb)-...

    Authors: Ping Li, Shuo Lin, Ling Li, Jinhui Cui, Shuisheng Zhou and Jianhui Fan

    Citation: BMC Endocrine Disorders 2018 18:64

    Published on:

  20. Content type: Study protocol

    Type 2 diabetes is a serious clinical problem in both India and the UK. Adoption of a healthy lifestyle through dietary and physical activity modification can help prevent type 2 diabetes. However, implementin...

    Authors: Hazel Thomson, Nick Oliver, Ian F. Godsland, Ara Darzi, Weerachai Srivanichakorn, Azeem Majeed, Desmond G. Johnston, Arun Nanditha, Chamukuttan Snehalatha, Arun Raghavan, Priscilla Susairaj, Mary Simon, Krishnamoorthy Satheesh, Ambady Ramachandran, Stephen Sharp, Kate Westgate…

    Citation: BMC Endocrine Disorders 2018 18:63

    Published on:

  21. Content type: Research article

    The aim of this study was to assess inadequate glycaemic control and its associated factors among people with type 2 diabetes in Saudi Arabia.

    Authors: Mohammed J. Alramadan, Dianna J. Magliano, Turky H. Almigbal, Mohammed Ali Batais, Afsana Afroz, Hesham J. Alramadhan, Waad Faozi Mahfoud, Adel Mehmas Alragas and Baki Billah

    Citation: BMC Endocrine Disorders 2018 18:62

    Published on:

  22. Content type: Research article

    The aim of the present study is to evaluate the association between BMD and type 2 DM status in middle-aged and elderly men. To investigate a possible correlation, the present study used the BMD dataset of the...

    Authors: Miso Jang, Hyunkyung Kim, Shorry Lea, Sohee Oh, Jong Seung Kim and Bumjo Oh

    Citation: BMC Endocrine Disorders 2018 18:61

    Published on:

  23. Content type: Research article

    Intestinal bacteria influence bone remodeling in rodents, and antibiotic manipulation of the rodent gut microbiota increases bone formation and prevents ovariectomy-induced bone loss. In theory, these effects ...

    Authors: Kristian H. Mikkelsen, Tina Vilsbøll, Jens J. Holst, Bolette Hartmann, Filip K. Knop and Morten Frost

    Citation: BMC Endocrine Disorders 2018 18:60

    Published on:

  24. Content type: Research article

    Galactomannan(s) are plant-derived fiber shown to reduce post-prandial blood glucose by delaying intestinal absorption of carbohydrates and slowing down gastric emptying. We examined glucose-lowering effects o...

    Authors: Andrea O. Y. Luk, Benny C. Y. Zee, Marc Chong, Risa Ozaki, Carl W. Rausch, Michael H. M. Chan, Ronald C. W. Ma, Alice P. S. Kong, Francis C. C. Chow and Juliana C. N. Chan

    Citation: BMC Endocrine Disorders 2018 18:59

    Published on:

  25. Content type: Research article

    Type 1 diabetes mellitus (T1DM) is one of the most common chronic diseases in children. Studies on costs related to T1DM are scarce and focused primarily on the costs directly related to diabetes. We aimed to ...

    Authors: E. A. J. M. Spaans, P. R. van Dijk, K. H. Groenier, P. L. P. Brand, N. Kleefstra and H. J. G. Bilo

    Citation: BMC Endocrine Disorders 2018 18:57

    Published on:

  26. Content type: Research article

    The shapes of the plasma glucose concentration curve during the oral glucose tolerance test are related to different metabolic risk profiles and future risk of type 2 DM. We sought to further analyze the relat...

    Authors: Leonardo de Andrade Mesquita, Luciana Pavan Antoniolli, Giordano Fabricio Cittolin-Santos and Fernando Gerchman

    Citation: BMC Endocrine Disorders 2018 18:56

    Published on:

  27. Content type: Research article

    Here we study the effect of type 2 diabetes (T2DM) on bone cell precursors, turnover and cytokines involved in the control of bone cell formation and activity.

    Authors: Francesca Sassi, Ilaria Buondonno, Chiara Luppi, Elena Spertino, Emanuela Stratta, Marco Di Stefano, Marco Ravazzoli, Gianluca Isaia, Marina Trento, Pietro Passera, Massimo Porta, Giovanni Carlo Isaia and Patrizia D’Amelio

    Citation: BMC Endocrine Disorders 2018 18:55

    Published on:

  28. Content type: Research article

    To compare the accuracy of different obesity indexes, including waist circumference (WC), weight-to-height ratio (WHtR), body mass index (BMI), and lipid accumulation product (LAP), in predicting metabolic syn...

    Authors: Leilei Liu, Yu Liu, Xizhuo Sun, Zhaoxia Yin, Honghui Li, Kunpeng Deng, Xu Chen, Cheng Cheng, Xinping Luo, Ming Zhang, Linlin Li, Lu Zhang, Bingyuan Wang, Yongcheng Ren, Yang Zhao, Dechen Liu…

    Citation: BMC Endocrine Disorders 2018 18:54

    Published on:

  29. Content type: Research article

    Diabetic foot ulceration is a serious limb-threatening complication of diabetes. It is the common cause of hospital admissions and amputations.

    Authors: Bilal Bin Younis, Adeela Shahid, Rozina Arshad, Saima Khurshid, Muhammad Ahmad and Haroon Yousaf

    Citation: BMC Endocrine Disorders 2018 18:53

    Published on:

  30. Content type: Research article

    Type 2 Diabetes Mellitus is a serious metabolic disease that is often associated with vascular complications. There are 1.9 million people living with Diabetes in Ethiopia; diabetes mellitus is found to be the...

    Authors: Haileab Fekadu Wolde, Asrat Atsedeweyen, Addisu Jember, Tadesse Awoke, Malede Mequanent, Adino Tesfahun Tsegaye and Shitaye Alemu

    Citation: BMC Endocrine Disorders 2018 18:52

    Published on:

  31. Content type: Research article

    The Ki-67 index in gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) may change throughout the disease course. However, the definitive effect of Ki-67 variability on GEP-NENs remains unknown. The aims...

    Authors: Huiying Shi, Qin Zhang, Chaoqun Han, Ding Zhen and Rong Lin

    Citation: BMC Endocrine Disorders 2018 18:51

    Published on:

  32. Content type: Research article

    Diabetes in the United States has reached epidemic proportions and the people of Appalachia have been disproportionately affected by this disease. Strategies that complement standard diabetes care are critical...

    Authors: Elizabeth A. Beverly, Jane Hamel-Lambert, Laura L. Jensen, Sue Meeks and Anne Rubin

    Citation: BMC Endocrine Disorders 2018 18:50

    Published on:

  33. Content type: Research article

    Glycaemic control is one of the most effective strategies for the treatment of diabetes-related erectile dysfunction (DMED). Compared to conventional anti-diabetic drugs and insulin, islet transplantation is m...

    Authors: Zhigang Wu, Hongwei Wang, Fubiao Ni, Xuan Jiang, Ziqiang Xu, Chengyang Liu, Yong Cai, Hongxing Fu, Jiao Luo, Wenwei Chen, Bicheng Chen and Zhixian Yu

    Citation: BMC Endocrine Disorders 2018 18:49

    Published on:

  34. Content type: Research article

    Vitamin D deficiency is a common health problem. Vitamin D supplements are used to improve vitamin D status; however, there are contradictory data related to what doses to give and how often they should be giv...

    Authors: Mahmut Apaydin, Asli Gencay Can, Muhammed Kizilgul, Selvihan Beysel, Seyfullah Kan, Mustafa Caliskan, Taner Demirci, Ozgur Ozcelik, Mustafa Ozbek and Erman Cakal

    Citation: BMC Endocrine Disorders 2018 18:48

    Published on:

  35. Content type: Research article

    Optimal glycaemia, reflected by glycated haemoglobin (HbA1c) levels, is key in reducing type 2 diabetes (T2D) complications. However, most people with T2D have suboptimal recall and understanding of HbA1c. Con...

    Authors: Mei Lyn Tan, Jo-Anne Manski-Nankervis, Sharmala Thuraisingam, Alicia Jenkins, David O’Neal and John Furler

    Citation: BMC Endocrine Disorders 2018 18:47

    Published on:

  36. Content type: Case report

    Papillary thyroid carcinoma with pleomorphic tumor giant cells (PTC-PC) is characterized by the occurrence of bizarre, pleomorphic cells within a small area of a conventional PTC. The histologic distinction be...

    Authors: Johan O. Paulsson, Jan Zedenius and C. Christofer Juhlin

    Citation: BMC Endocrine Disorders 2018 18:46

    Published on:

  37. Content type: Research article

    Incidence of dementia is growing rapidly and affects many people worldwide. Type 2 diabetes mellitus (DM) might link cognitive decline and dementia, but the reasons for this association remain unclear. Our stu...

    Authors: Chun-Lin Liu, Ming-Yen Lin, Shang-Jyh Hwang, Ching-Kuan Liu, Huei-Lan Lee and Ming-Tsang Wu

    Citation: BMC Endocrine Disorders 2018 18:45

    Published on:

  38. Content type: Research article

    Vitamin D deficiency is pandemic while resources available to measure 25-hydroxyvitamin D (25OHD) are limited. The present study aimed to verify whether sun exposure measured by a structured questionnaire coul...

    Authors: Fernanda Barros Bittar, Charlles H. M. Castro and Vera Lúcia Szejnfeld

    Citation: BMC Endocrine Disorders 2018 18:44

    Published on:

  39. Content type: Research article

    Diabetic foot is one of the most significant and devastating complication of diabetes. The objective of this study was to assess the prevalence of diabetic foot syndrome (DFS) and the associated risk factors a...

    Authors: S. P. Vibha, Muralidhar M. Kulkarni, A. B. Kirthinath Ballala, Asha Kamath and G. Arun Maiya

    Citation: BMC Endocrine Disorders 2018 18:43

    Published on:

  40. Content type: Research article

    The benefit results of postoperative tight glycemic control (TGC) were controversial and there was a lack of well-powered studies that support current guideline recommendations.

    Authors: Yuan-yuan Wang, Shuang-fei Hu, Hui-min Ying, Long Chen, Hui-li Li, Fang Tian and Zhen-feng Zhou

    Citation: BMC Endocrine Disorders 2018 18:42

    Published on:

  41. Content type: Case report

    Pheochromocytoma, especially for noncatecholamine-secreting pheochromocytoma, is an extremely rare cause of ectopic corticotrophin-releasing hormone (CRH) syndrome.

    Authors: Bao-Ping Wang, Lei-Lei Yang, Hao Wang, Qing He, Zhong-Shu Ma, Yi Lin, Chang-Xin Jiang, Hao-Ran Sun and Ming Liu

    Citation: BMC Endocrine Disorders 2018 18:41

    Published on:

  42. Content type: Research article

    Obesity and diabetes mellitus, or diabetes, are independently associated with post-ischemic stroke outcomes (e.g., functional disability and all-cause mortality). Although obesity and diabetes are also associated...

    Authors: Colleen Bauza, Sharon D. Yeatts, Keith Borg, Gayenell Magwood, Renee’ H. Martin, Anbesaw Selassie and Marvella E. Ford

    Citation: BMC Endocrine Disorders 2018 18:40

    Published on:

  43. Content type: Research article

    The prevalence of childhood obesity and obesity-related metabolic disorder such as dyslipidemia has sharply increased in the past few decades. Chronic low-grade inflammation is associated with the development ...

    Authors: Yuesheng Liu, Dong Xu, Chunyan Yin, Sisi Wang, Min Wang and Yanfeng Xiao

    Citation: BMC Endocrine Disorders 2018 18:39

    Published on:

  44. Content type: Research article

    Testosterone signals through the androgen receptor (AR) and AR knockout mice develop obesity, suggesting a functional association between AR and leptin signaling. Furthermore, physiological blood concentration...

    Authors: Koichi Yabiku, Keiko Nakamoto and Akihiro Tokushige

    Citation: BMC Endocrine Disorders 2018 18:38

    Published on:

  45. Content type: Research article

    Nivolumab, an anti-programmed cell death-1 monoclonal antibody, has improved the survival of patients with malignant melanoma. Despite its efficacy, nivolumab inconsistently induces thyroid dysfunction as an i...

    Authors: Seiichi Yano, Kenji Ashida, Hiromi Nagata, Kenji Ohe, Naoko Wada, Yukina Takeichi, Yuki Hanada, Yuta Ibayashi, Lixiang Wang, Shohei Sakamoto, Ryuichi Sakamoto, Hiroshi Uchi, Motoaki Shiratsuchi, Masutaka Furue, Masatoshi Nomura and Yoshihiro Ogawa

    Citation: BMC Endocrine Disorders 2018 18:36

    Published on:

  46. Content type: Research article

    Hypoglycaemia is a feared experience for people with diabetes. We aimed to study the prevalence and causes of hypoglycaemia among Sri Lankans with diabetes.

    Authors: H. A. Dissanayake, G. S. P. Keerthisena, K. K. K. Gamage, J. H. Liyanage, I. R. H. S. Ihalagama, W. M. U. A. Wijetunga, T. A. D. Tillekaratne, G. W. Katulanda and P. Katulanda

    Citation: BMC Endocrine Disorders 2018 18:35

    Published on: