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  1. The aim of the present study is to examine the clinical indices related to cardiovascular risk management of Greek patients with type 2 diabetes, before and after the major economic crisis that emerged in the ...

    Authors: Stavros Liatis, Stavroula Papaoikonomou, Asimina Ganotopoulou, Athanasia Papazafiropoulou, Constantinos Dinos, Marios Michail, Apostolos Xilomenos, Andreas Melidonis and Stavros Pappas

    Citation: BMC Endocrine Disorders 2014 14:23

    Content type: Research article

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  2. Due to ongoing rise in need for care for people with chronic diseases and lagging increase in number of care providers, alternative forms of care provision and self-management support are needed. Empowering pa...

    Authors: Yvonne Roelofsen, Steven H Hendriks, Floor Sieverink, Michael van Vugt, Kornelis JJ van Hateren, Frank J Snoek, Maartje de Wit, Rijk OB Gans, Klaas H Groenier, Julia EWC van Gemert-Pijnen, Nanne Kleefstra and Henk JG Bilo

    Citation: BMC Endocrine Disorders 2014 14:22

    Content type: Study protocol

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  3. Many type 2 diabetes mellitus patients face difficulties self-managing their illness, which can lead to high levels of diabetes-related distress. Diabetes distress may be decreased by peer support, as peers un...

    Authors: Lianne de Vries, Amber AWA van der Heijden, Esther van 't Riet, Caroline A Baan, Piet J Kostense, Mieke Rijken, Guy EHM Rutten and Giel Nijpels

    Citation: BMC Endocrine Disorders 2014 14:21

    Content type: Study protocol

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  4. Diabetic retinopathy (DR) is one of the leading causes for complete loss of vision among working-aged adults around the world. The present study aims to evaluate the rate of DR and its risk factors among the a...

    Authors: Prasad Katulanda, Yasindu C Waniganayake, Priyanga Ranasinghe, WM Udai Akalanka Wijetunga, Mahesh Jayaweera, Nishantha P Wijesinghe, Rezvi Sheriff and David R Matthews

    Citation: BMC Endocrine Disorders 2014 14:20

    Content type: Research article

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  5. Hyperglycemia induces chromatin remodeling with consequences on differential gene expression in mouse hepatocytes, similar to what occurs during aging. The liver is the central organ for the regulation of gluc...

    Authors: Flávia G Ghiraldini, André B Silveira, Dirk A Kleinjan, Nick Gilbert and Maria Luiza S Mello

    Citation: BMC Endocrine Disorders 2014 14:19

    Content type: Research article

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  6. Hyperhomocysteinemia is a well-known cardiovascular risk factor and its elevation is established in overt hypothyroidism. Since some authors suggest that chronic autoimmune thyroiditis per se may be considered...

    Authors: Maciej Owecki, Jolanta Dorszewska, Nadia Sawicka-Gutaj, Anna Oczkowska, Michał K Owecki, Michał Michalak, Jakub Fischbach, Wojciech Kozubski and Marek Ruchała

    Citation: BMC Endocrine Disorders 2014 14:18

    Content type: Research article

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  7. To compare the safety and efficacy of saxagliptin 2.5 mg twice daily (BID) versus placebo add-on therapy to metformin immediate release (IR) in patients with type 2 diabetes and inadequate glycemic control wit...

    Authors: Judith L White, Patricia Buchanan, Jia Li and Robert Frederich

    Citation: BMC Endocrine Disorders 2014 14:17

    Content type: Research article

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  8. Aromatase deficiency is a rare, autosomal recessive disorder of which there are approximately twenty four case reports. The aromatase enzyme is crucial in the biosynthesis of oestrogens from androgens. The phe...

    Authors: Lucia Gagliardi, Hamish S Scott, Jinghua Feng and David J Torpy

    Citation: BMC Endocrine Disorders 2014 14:16

    Content type: Case report

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  9. The possible association between metabolic syndrome (MS) and bone mineral density (BMD) has been highlighted recently. However, the exact effects of MS on calcaneal quantitative ultrasound (QUS) parameters rem...

    Authors: Min Sun, Mengdie Cao, Qi Fu, Zhenxin Zhu, Chuchen Meng, Jia Mao, Yun Shi, Yu Duan, Wei Tang, Xiaoping Huang, Wei He and Tao Yang

    Citation: BMC Endocrine Disorders 2014 14:14

    Content type: Research article

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  10. Emerging epidemiological evidence suggest an association between metabolic syndrome and fractures. However, whether metabolic syndrome is an independent risk or protective factor of fractures remains controver...

    Authors: Kan Sun, Jianmin Liu, Nan Lu, Hanxiao Sun and Guang Ning

    Citation: BMC Endocrine Disorders 2014 14:13

    Content type: Research article

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  11. Steroid cell tumors of ovary account for less than 0.1% of all ovarian tumors and these tumours may present at any age in association with interesting presentations related to hormonal activities. The subtype,...

    Authors: Menghua Yuan, Mingcai Qiu and Mei Zhu

    Citation: BMC Endocrine Disorders 2014 14:12

    Content type: Case report

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  12. Diabetic cardiomyopathy is associated with a number of functional and structural pathological changes such as left ventricular dysfunction, cardiac remodeling, and apoptosis. The primary cause of diabetic card...

    Authors: Romana Bohuslavova, Frantisek Kolar, David Sedmera, Lada Skvorova, Frantisek Papousek, Jan Neckar and Gabriela Pavlinkova

    Citation: BMC Endocrine Disorders 2014 14:11

    Content type: Research article

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  13. Thyroid dysfunction is a common complication of chronic hepatitis C (CHC) and its therapy. Takotsubo cardiomyopathy (TCM) is a multifactorial, stress related cardiomyopathy, rarely reported in association with th...

    Authors: Carmen Sorina Martin, Luminita Nicoleta Ionescu, Carmen Gabriela Barbu, Anca Elena Sirbu, Ioana Maria Lambrescu, Ioana Smarandita Lacau, Doina Ruxandra Dimulescu and Simona Vasilica Fica

    Citation: BMC Endocrine Disorders 2014 14:10

    Content type: Case report

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  14. Not all obese subjects have an adverse metabolic profile predisposing them to developing type 2 diabetes or cardiovascular disease. The BioSHaRE-EU Healthy Obese Project aims to gain insights into the conseque...

    Authors: Jana V van Vliet-Ostaptchouk, Marja-Liisa Nuotio, Sandra N Slagter, Dany Doiron, Krista Fischer, Luisa Foco, Amadou Gaye, Martin Gögele, Margit Heier, Tero Hiekkalinna, Anni Joensuu, Christopher Newby, Chao Pang, Eemil Partinen, Eva Reischl, Christine Schwienbacher…

    Citation: BMC Endocrine Disorders 2014 14:9

    Content type: Research article

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  15. The rate of bone turnover is closely related to osteoporosis risk. We investigated the correlation between bone turnover markers and BMD at various skeletal sites in healthy native Chinese women, and to study ...

    Authors: Xi-Yu Wu, Hong-Li Li, Hui Xie, Xiang-Hang Luo, Yi-Qun Peng, Ling-Qing Yuan, Zhi-Feng Sheng, Ru-Chun Dai, Xian-Ping Wu and Er-Yuan Liao

    Citation: BMC Endocrine Disorders 2014 14:8

    Content type: Research article

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  16. Adipose tissue (AT) contributes to metabolic dysfunction through imbalanced production of adipokines, including cytokines. Visceral AT in particular is associated with metabolic disorders, indicating a specifi...

    Authors: Henrik Svensson, Birgitta Odén, Staffan Edén and Malin Lönn

    Citation: BMC Endocrine Disorders 2014 14:7

    Content type: Research article

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  17. Thyroid metastases are clinically rare, and usually occur in patients with a history of prior malignancy and when there are metastases elsewhere. Metastases of pancreatic carcinoma to the thyroid are extremely...

    Authors: Alessandro P Delitala, Gianpaolo Vidili, Alessandra Manca, Upinder Dial, Giuseppe Delitala and Giuseppe Fanciulli

    Citation: BMC Endocrine Disorders 2014 14:6

    Content type: Case report

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  18. A diagnosis of subacute thyroiditis is readily considered when patients present with a particular set of typical clinical characteristics. Subacute thyroiditis sometimes presents as a solitary cold nodule; how...

    Authors: Lian-Xi Li, Xing Wu, Bing Hu, Hui-Zhen Zhang and Han-Kui Lu

    Citation: BMC Endocrine Disorders 2014 14:4

    Content type: Case report

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  19. Trisomy 9p is an uncommon anomaly characterised by mental retardation, head and facial abnormalities, congenital heart defects, kidney abnormalities, and skeletal malformations. Affected children may also show...

    Authors: Stefano Stagi, Elisabetta Lapi, Salvatore Seminara, Silvia Guarducci, Marilena Pantaleo, Sabrina Giglio, Francesco Chiarelli and Maurizio de Martino

    Citation: BMC Endocrine Disorders 2014 14:3

    Content type: Research article

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  20. Several studies have shown the association of solute carrier family 30 (zinc transporter) member 8 (SLC30A8) rs13266634 with type 2 diabetes (T2D). However, the association of alternative variants and haplotyp...

    Authors: Sameer D Salem, Riyadh Saif-Ali, Ikram S Ismail, Zaid Al-Hamodi and Sekaran Muniandy

    Citation: BMC Endocrine Disorders 2014 14:2

    Content type: Research article

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  21. Studies have shown that group Therapeutic Patient Education (TPE) may empower patients with type 2 diabetes to better manage their disease. The mechanism of these interventions is not fully understood. A reduc...

    Authors: Liora Valinsky, Moshe Mishali, Ronit Endevelt, Rachel Preiss, Keren Dopelt and Anthony D Heymann

    Citation: BMC Endocrine Disorders 2013 13:61

    Content type: Research article

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  22. Existing inconclusive data on the relationship between vitamin D status and human glucose homeostasis suggests that other factors, such as adiposity, might influence this relationship. The present study aimed ...

    Authors: Hataikarn Nimitphong, La-or Chailurkit, Suwannee Chanprasertyothin, Piyamitr Sritara and Boonsong Ongphiphadhanakul

    Citation: BMC Endocrine Disorders 2013 13:60

    Content type: Research article

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  23. One possible barrier to effective diabetes self-management is hypoglycaemia associated with diabetes medication. The current study was conducted to characterize hypoglycaemic events among UK patients with type...

    Authors: Beth D Mitchell, Jeffrey Vietri, Anthony Zagar, Bradley Curtis and Matthew Reaney

    Citation: BMC Endocrine Disorders 2013 13:59

    Content type: Research article

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  24. The discovery of sodium-glucose co-transporter 2 (SGLT2) inhibitors, with a novel mechanism independent of insulin secretion or sensitization, bring about a new therapeutic approach to the management of type 2...

    Authors: Asres Berhan and Alex Barker

    Citation: BMC Endocrine Disorders 2013 13:58

    Content type: Research article

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  25. Lifestyle intervention in type 2 diabetes mellitus (T2DM) is effective but needs a special local setting and is costly. Therefore, in a randomized-controlled trial we tested the hypothesis that the autonomous ...

    Authors: Kerstin Kempf and Stephan Martin

    Citation: BMC Endocrine Disorders 2013 13:57

    Content type: Research article

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  26. The complex process of development of the pituitary gland is regulated by a number of signalling molecules and transcription factors. Mutations in these factors have been identified in rare cases of congenital...

    Authors: Jana Breitfeld, Susanne Martens, Jürgen Klammt, Marina Schlicke, Roland Pfäffle, Kerstin Krause, Kerstin Weidle, Dorit Schleinitz, Michael Stumvoll, Dagmar Führer, Peter Kovacs and Anke Tönjes

    Citation: BMC Endocrine Disorders 2013 13:56

    Content type: Research article

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  27. Around 10 per cent of catecholamine-secreting tumours can be found outside the adrenal medulla (paraganglioma). We report a case of a functional sporadic paraganglioma that was localized lateral to the prostat...

    Authors: Jesper Kers, Zaheeb A Choudhry, Ton A Roeleveld and Alexander PJ Houdijk

    Citation: BMC Endocrine Disorders 2013 13:55

    Content type: Case report

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  28. Allograft inflammatory factor 1 (AIF-1) is a putative obesity gene. Our aim was to examine the expression of AIF-1 in human white adipose tissue (WAT) in relation to obesity and metabolic phenotypes in women.

    Authors: Silvia Lorente-Cebrián, Pauline Decaunes, Elisabeth Dungner, Anne Bouloumié, Peter Arner and Ingrid Dahlman

    Citation: BMC Endocrine Disorders 2013 13:54

    Content type: Research article

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  29. Self-management is recognized as the cornerstone of overall diabetes management. Web-based self-management programs have the potential of supporting type 2 diabetes patients with managing their diabetes and re...

    Authors: Michael van Vugt, Maartje de Wit, Steven H Hendriks, Yvonne Roelofsen, Henk JG Bilo and Frank J Snoek

    Citation: BMC Endocrine Disorders 2013 13:53

    Content type: Study protocol

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  30. Testing for 25-hydroxyvitamin D [25(OH)D] has increased dramatically in recent years. The present report compares overall utilization and results for 25(OH)D orders at two academic medical centers - one in New...

    Authors: Jonathan R Genzen, Jennifer T Gosselin, Thomas C Wilson, Emilian Racila and Matthew D Krasowski

    Citation: BMC Endocrine Disorders 2013 13:52

    Content type: Research article

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  31. Over the last few years, awareness and detection rates of hypopituitarism following traumatic brain injury (TBI) and subarachnoid hemorrhage (SAH) has steadily increased. Moreover, recent studies have found th...

    Authors: Steffen Kristian Fleck, Henri Wallaschofski, Christian Rosenstengel, Marc Matthes, Thomas Kohlmann, Matthias Nauck, Henry Werner Siegfried Schroeder and Christin Spielhagen

    Citation: BMC Endocrine Disorders 2013 13:51

    Content type: Research article

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  32. Iodine deficiency affects nearly 1.9 billion people worldwide, but it can be prevented by salt iodization. This cross-sectional survey assessed current iodine status, iodized salt coverage and risk factors for...

    Authors: Barbara Matthys, Mohbegim Davlatmamadova, Gulzira Karimova, Vreni Jean-Richard, Michael B Zimmermann and Kaspar Wyss

    Citation: BMC Endocrine Disorders 2013 13:50

    Content type: Research article

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  33. Immigrants from South Asia to Western countries have a high prevalence of type 2 diabetes mellitus (T2DM). We explored pathogenic factors that might contribute to the high risk of T2DM in Pakistani immigrants ...

    Authors: Cecilie Wium, Erlend T Aasheim, Thor Ueland, Annika E Michelsen, Per M Thorsby, Ingegerd F Larsen, Peter A Torjesen, Pål Aukrust and Kåre I Birkeland

    Citation: BMC Endocrine Disorders 2013 13:49

    Content type: Research article

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  34. Familial papillary thyroid cancer (fPTC) is recognized as a distinct entity only recently and no fPTC predisposing genes have been identified. Several potential regions and susceptibility loci for sporadic PTC...

    Authors: Shunyao Liao, Wenzhong Song, Yunqiang Liu, Shaoping Deng, Yaming Liang, Zhenlin Tang, Jiyuan Huang, Dandan Dong and Gang Xu

    Citation: BMC Endocrine Disorders 2013 13:48

    Content type: Research article

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  35. Insulin resistance has been associated with metabolic and hemodynamic alterations and higher cardio metabolic risk. There is great variability in the threshold homeostasis model assessment of insulin resistanc...

    Authors: Pilar Gayoso-Diz, Alfonso Otero-González, María Xosé Rodriguez-Alvarez, Francisco Gude, Fernando García, Angel De Francisco and Arturo González Quintela

    Citation: BMC Endocrine Disorders 2013 13:47

    Content type: Research article

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  36. To examine the views and current practice of SMBG among Black Caribbean and South Asian individuals with non-insulin treated Type 2 diabetes mellitus.

    Authors: Enza Gucciardi, Mariella Fortugno, Andrea Senchuk, Heather Beanlands, Elizabeth McCay and Elizabeth E Peel

    Citation: BMC Endocrine Disorders 2013 13:46

    Content type: Research article

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  37. Diffuse large B-cell lymphoma sometimes involves the endocrine organs, but involvement of both the pituitary and adrenal glands is extremely rare. Involvement of these structures can lead to hypopituitarism an...

    Authors: Yasuhiro Nakashima, Motoaki Shiratsuchi, Ichiro Abe, Yayoi Matsuda, Noriyuki Miyata, Hirofumi Ohno, Motohiko Ikeda, Takamitsu Matsushima, Masatoshi Nomura and Ryoichi Takayanagi

    Citation: BMC Endocrine Disorders 2013 13:45

    Content type: Case report

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  38. Glycosylated hemoglobin A1c (HbA1c) has been applied to identify type 2 diabetes (T2DM) in the U.S. and European countries. It has not been used in China mainly due to lack of a standardized approach to measure H...

    Authors: Miao Mo, Weijian Zhong, Genming Zhao, Ye Ruan, Hua Zhang, Liang Shi, Dajiang Lu, Qundi Yang, Yanyun Li, Qingwu Jiang, Rui Li and Wang-Hong Xu

    Citation: BMC Endocrine Disorders 2013 13:44

    Content type: Research article

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  39. Traditional lipid indices have been associated with type 2 diabetes, but it remains uncertain which lipid index is the best discriminator for diabetes. In this study, we aimed to assess lipoproteins, tradition...

    Authors: Zhi-Hong Jian, Chia-Chi Lung, Pei-Chieh Ko, Yi-Hua Sun, Jing-Yang Huang, Chien-Chang Ho, Chia-Yo Ho, Yi-Chen Chiang, Chien-Jen Chen and Yung-Po Liaw

    Citation: BMC Endocrine Disorders 2013 13:42

    Content type: Research article

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  40. The detection of microvascular damage in type 1 diabetes is difficult and traditional investigations do not detect changes until they are well established. The purpose of this study was to investigate the comb...

    Authors: Sarah P M Hosking, Rani Bhatia, Patricia A Crock, Ian Wright, Marline L Squance and Glenn Reeves

    Citation: BMC Endocrine Disorders 2013 13:41

    Content type: Research article

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  41. Animal studies have shown that zinc intake has protective effects against type 2 diabetes, but few studies have been conducted to examine this relationship in humans. The aim of this study is to investigate if...

    Authors: Khanrin Phungamla Vashum, Mark McEvoy, Zumin Shi, Abul Hasnat Milton, Md Rafiqul Islam, David Sibbritt, Amanda Patterson, Julie Byles, Deborah Loxton and John Attia

    Citation: BMC Endocrine Disorders 2013 13:40

    Content type: Research article

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  42. A considerable interest has been drawn to potential protective effects of bilirubin against oxidative stress-related diseases. Smoking is known to be associated with lower concentrations of serum bilirubin, bu...

    Authors: Maya Tanaka, Sanjeev Budhathoki, Akie Hirata, Makiko Morita, Suminori Kono, Masahiro Adachi, Hisaya Kawate, Keizo Ohnaka and Ryoichi Takayanagi

    Citation: BMC Endocrine Disorders 2013 13:39

    Content type: Research article

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  43. Obesity is associated with insulin resistance, development of diabetes, and coronary heart disease. There is limited information on the contribution of previous obesity on the risk of coronary heart disease. W...

    Authors: Ritsuko Yamamoto-Honda, Hideki Ehara, Hiroji Kitazato, Yoshihiko Takahashi, Shoji Kawazu, Yasuo Akanuma and Mitsuhiko Noda

    Citation: BMC Endocrine Disorders 2013 13:38

    Content type: Research article

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  44. To examine the effects of physical activity on the development and progression of microvascular complications in patients with type 1 diabetes.

    Authors: Caroline BT Makura, Krishnarajah Nirantharakumar, Alan J Girling, Ponnusamy Saravanan and Parth Narendran

    Citation: BMC Endocrine Disorders 2013 13:37

    Content type: Research article

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  45. Our aim was to assess the associations between vitamin D (vitD) status, metabolic profile and polymorphisms in genes involved in the transport (Group-Component: GC) and the hydroxylation (NAD synthetase 1: NADSYN...

    Authors: Lydia Foucan, Fritz-Line Vélayoudom-Céphise, Laurent Larifla, Christophe Armand, Jacqueline Deloumeaux, Cedric Fagour, Jean Plumasseau, Marie-Line Portlis, Longjian Liu, Fabrice Bonnet and Jacques Ducros

    Citation: BMC Endocrine Disorders 2013 13:36

    Content type: Research article

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  46. Ghrelin and peptide YY (PYY) are appetite regulating hormones secreted from the gastrointestinal tract (gut). Aside from their known effect on energy homeostasis, accumulating data indicates that these gut hor...

    Authors: Peyvand Amini, Farrell Cahill, Danny Wadden, Yunqi Ji, Pardis Pedram, Sangeetha Vidyasankar, Yanqing Yi, Wayne Gulliver, Gary Paterno, Hongwei Zhang, Alecia Rideout and Guang Sun

    Citation: BMC Endocrine Disorders 2013 13:35

    Content type: Research article

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  47. Alterations in the naive T cell subpopulations have been demonstrated in patients with T cell mediated autoimmune disorders, reminiscent of immunological changes found in the elderly during immunosenescence, i...

    Authors: Martina Prelog, Jörn Schönlaub, Reinhard Würzner, Christian Koppelstaetter, Giovanni Almanzar, Andrea Brunner, Martin Gasser, Rupert Prommegger, Gabriele Häusler, Klaus Kapelari and Wolfgang Högler

    Citation: BMC Endocrine Disorders 2013 13:34

    Content type: Research article

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