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  1. Most studies on cortisol have focused on smaller, selected samples. We therefore aimed to sex-specifically study the diurnal cortisol pattern and explore its association with abdominal obesity in a large unsel...

    Authors: Charlotte A Larsson, Bo Gullberg, Lennart Råstam and Ulf Lindblad

    Citation: BMC Endocrine Disorders 2009 9:16

    Content type: Research article

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  2. While there are compelling observational data confirming that individuals who exercise are healthier, the efficacy of aerobic exercise interventions to reduce metabolic risk and improve insulin sensitivity in ...

    Authors: Francis M Finucane, Jessica Horton, Lisa R Purslow, David B Savage, Soren Brage, Hervé Besson, Kenneth Horton, Ema De Lucia Rolfe, Alison Sleigh, Stephen J Sharp, Helen J Martin, Avan Aihie Sayer, Cyrus Cooper, Ulf Ekelund, Simon J Griffin and Nicholas J Wareham

    Citation: BMC Endocrine Disorders 2009 9:15

    Content type: Study protocol

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  3. The rising prevalence of type 2 diabetes underlines the importance of secondary strategies for the prevention of target organ damage. While access to diabetes education centers and diabetes intensification man...

    Authors: Sheldon W Tobe, Joan Wentworth, Laurie Ironstand, Susan Hartman, Jackie Hoppe, Judi Whiting, Janice Kennedy, Colin McAllister, Alex Kiss, Nancy Perkins, Lloyd Vincent, George Pylypchuk and Richard Z Lewanczuk

    Citation: BMC Endocrine Disorders 2009 9:13

    Content type: Study protocol

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  4. A lot of studies have showed an excess maternal transmission of type 2 diabetes (T2D). The aim, therefore, of the present study was to estimate the prevalence of familial history of T2D in Greek patients, and ...

    Authors: Athanasia Papazafiropoulou, Alexios Sotiropoulos, Eystathios Skliros, Marina Kardara, Anthi Kokolaki, Ourania Apostolou and Stavros Pappas

    Citation: BMC Endocrine Disorders 2009 9:12

    Content type: Research article

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  5. Primary aldosteronism (PA) affects approximately 5 to 10% of all patients with arterial hypertension and is associated with an excess rate of cardiovascular complications that can be significantly reduced by a...

    Authors: Stefan Pilz, Andreas Tomaschitz, Vinzenz Stepan, Barbara Obermayer-Pietsch, Astrid Fahrleitner-Pammer, Natascha Schweighofer, Horst R Portugaller, Harald Sourij, Harald Dobnig, Andreas Meinitzer and Thomas R Pieber

    Citation: BMC Endocrine Disorders 2009 9:11

    Content type: Study protocol

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  6. All the peroxisome proliferator activated receptors (PPARs) are found to be expressed in bone cells. The PPARγ agonist rosiglitazone has been shown to decrease bone mass in mice and thiazolidinediones (TZDs) h...

    Authors: Unni Syversen, Astrid K Stunes, Björn I Gustafsson, Karl J Obrant, Lars Nordsletten, Rolf Berge, Liv Thommesen and Janne E Reseland

    Citation: BMC Endocrine Disorders 2009 9:10

    Content type: Research article

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  7. Hyperglycaemic emergencies are common acute complications of diabetes mellitus (DM) but unfortunately, there is a dearth of published data on this entity from Nigeria. This study attempts to describe the clini...

    Authors: Anthonia O Ogbera, Jacob Awobusuyi, Chioma Unachukwu and Olufemi Fasanmade

    Citation: BMC Endocrine Disorders 2009 9:9

    Content type: Research article

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  8. Rosiglitazone not only improves insulin-sensitivity, but also exerts anti-inflammatory effects. We have now examined in type 2 diabetic patients if these effects are reflected by changes in mRNA expression in ...

    Authors: Marjolijn CE Bragt, Jogchum Plat, Marco Mensink, Patrick Schrauwen and Ronald P Mensink

    Citation: BMC Endocrine Disorders 2009 9:8

    Content type: Research article

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  9. β-cells are extremely rich in zinc and zinc homeostasis is regulated by zinc transporter proteins. β-cells are sensitive to cytokines, interleukin-1β (IL-1β) has been associated with β-cell dysfunction and -de...

    Authors: Lærke Egefjord, Jens Ledet Jensen, Claus Heiner Bang-Berthelsen, Andreas Brønden Petersen, Kamille Smidt, Ole Schmitz, Allan Ertman Karlsen, Flemming Pociot, Fabrice Chimienti, Jørgen Rungby and Nils E Magnusson

    Citation: BMC Endocrine Disorders 2009 9:7

    Content type: Research article

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  10. The management of diabetes self-care is largely the responsibility of the patient. With more emphasis on the prevention of complications, adherence to diabetes self-care regimens can be difficult. Diabetes sel...

    Authors: Margaret M Collins, Colin P Bradley, Tony O'Sullivan and Ivan J Perry

    Citation: BMC Endocrine Disorders 2009 9:6

    Content type: Research article

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  11. The objective was to examine how the indigenous naming, indigenous self-diagnosis and management of diabetes evolved with awareness in order to develop a socially oriented theoretical model for its care.

    Authors: Paschal K Awah, Nigel C Unwin and Peter R Phillimore

    Citation: BMC Endocrine Disorders 2009 9:5

    Content type: Research article

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  12. Vitamin D deficiency is associated with heightened risk of cardiovascular disease. Potential mechanisms include involvement of vitamin D in regulation of renin-angiotensin system and manufacture and secretion ...

    Authors: Hussein F Saadi, M Gary Nicholls, Christopher M Frampton, Sheela Benedict and Javed Yasin

    Citation: BMC Endocrine Disorders 2009 9:4

    Content type: Research article

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  13. Traditional high volume aerobic exercise training reduces cardiovascular and metabolic disease risk but involves a substantial time commitment. Extremely low volume high-intensity interval training (HIT) has r...

    Authors: John A Babraj, Niels BJ Vollaard, Cameron Keast, Fergus M Guppy, Greg Cottrell and James A Timmons

    Citation: BMC Endocrine Disorders 2009 9:3

    Content type: Research article

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  14. Diabetes has become the single most common cause for end-stage renal disease in the United States. It has been established that mitochondrial damage occurs during diabetes; however, little is known about what ...

    Authors: Shankar Munusamy, Hamida Saba, Tanecia Mitchell, Judit K Megyesi, Robert W Brock and Lee Ann MacMillan-Crow

    Citation: BMC Endocrine Disorders 2009 9:2

    Content type: Research article

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  15. Visceral obesity is positively related to insulin resistance. The nature of the relationship between waist circumference and insulin resistance has not been known in Japanese populations. This study examined t...

    Authors: Shinji Tabata, Shinichiro Yoshimitsu, Tadamichi Hamachi, Hiroshi Abe, Keizo Ohnaka and Suminori Kono

    Citation: BMC Endocrine Disorders 2009 9:1

    Content type: Research article

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  16. Diabetes mellitus is becoming increasingly common in sub-Saharan Africa. Autonomic dysfunction contributes to morbidity and mortality in diabetic patients. Data on autonomic dysfunction in the African populati...

    Authors: Malvin Torsvik, Amanda Häggblom, Geir Egil Eide, Erich Schmutzhard, Kaare Vetvik and Andrea Sylvia Winkler

    Citation: BMC Endocrine Disorders 2008 8:19

    Content type: Research article

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  17. Risk factors underlying the development and progression of some of the less well-recognised complications of type 2 diabetes, including cognitive impairment and non-alcoholic fatty liver disease, are poorly un...

    Authors: Jackie F Price, Rebecca M Reynolds, Rory J Mitchell, Rachel M Williamson, F Gerald R Fowkes, Ian J Deary, Amanda J Lee, Brian M Frier, Peter C Hayes and Mark WJ Strachan

    Citation: BMC Endocrine Disorders 2008 8:18

    Content type: Study protocol

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  18. Angiotensin converting enzyme inhibitors (ACE inhibitors) reduce peripheral vascular resistance via blockage of angiotensin converting enzyme (ACE). ACE inhibitors are commonly used to treat congestive heart f...

    Authors: Maria E Ramos-Nino, Charles D MacLean and Benjamin Littenberg

    Citation: BMC Endocrine Disorders 2008 8:17

    Content type: Research article

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  19. Various structural and functional factors of foot function have been associated with high local plantar pressures. The therapist focuses on these features which are thought to be responsible for plantar ulcera...

    Authors: Nick A Guldemond, Pieter Leffers, Geert HIM Walenkamp, Nicolaas C Schaper, Antal P Sanders, Fred HM Nieman and Lodewijk W van Rhijn

    Citation: BMC Endocrine Disorders 2008 8:16

    Content type: Research article

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  20. Age- and sex-specific reference intervals are an important prerequisite for interpreting thyroid hormone measurements in children. However, only few studies have reported age- and sex-specific pediatric refere...

    Authors: Klaus Kapelari, Christine Kirchlechner, Wolfgang Högler, Katharina Schweitzer, Irene Virgolini and Roy Moncayo

    Citation: BMC Endocrine Disorders 2008 8:15

    Content type: Research article

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  21. Sitagliptin, a highly selective dipeptidyl peptidase-4 inhibitor, is the first in a new class of oral antihyperglycemic agents (AHAs) for the treatment of patients with type 2 diabetes. Type 2 diabetes is a li...

    Authors: Debora Williams-Herman, Elizabeth Round, Arlene S Swern, Bret Musser, Michael J Davies, Peter P Stein, Keith D Kaufman and John M Amatruda

    Citation: BMC Endocrine Disorders 2008 8:14

    Content type: Research article

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  22. Non-thyroidal illness syndrome (NTIS) is a characteristic functional constellation of thyrotropic feedback control that frequently occurs in critically ill patients. Although this condition is associated with ...

    Authors: Johannes W Dietrich, Axel Stachon, Biljana Antic, Harald H Klein and Steffen Hering

    Citation: BMC Endocrine Disorders 2008 8:13

    Content type: Study protocol

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  23. Telomeres are DNA repeat sequences necessary for DNA replication which shorten at cell division at a rate directly related to levels of oxidative stress. Critical telomere shortening predisposes to cell senesc...

    Authors: Deepak Kejariwal, Karolina M Stepien, Tracy Smith, Hugh Kennedy, David A Hughes and Mike J Sampson

    Citation: BMC Endocrine Disorders 2008 8:12

    Content type: Research article

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  24. Ninety percent of cases of diabetes are of the slowly evolving non-insulin-dependent type, or Type 2 diabetes. Lack of exercise is regarded as one of the main causes of this disorder. In this study we analyzed...

    Authors: Clécia Soares de Alencar Mota, Carla Ribeiro, Gustavo Gomes de Araújo, Michel Barbosa de Araújo, Fúlvia de Barros Manchado-Gobatto, Fabrício Azevedo Voltarelli, Camila Aparecida Machado de Oliveira, Eliete Luciano and Maria Alice Rostom de Mello

    Citation: BMC Endocrine Disorders 2008 8:11

    Content type: Research article

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  25. The role of estrogens in male physiology has become evident. However, clinically useful normative data for estradiol secretion in boys has not previously been established due to the insensitivity of current me...

    Authors: Carina Ankarberg-Lindgren and Ensio Norjavaara

    Citation: BMC Endocrine Disorders 2008 8:10

    Content type: Research article

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  26. To estimate the proportion of diabetic patients (DPts) with peripheral vascular disease treated at a primary health care site after an endocrinologist-based intervention, who meet ATP III and Steno targets of ...

    Authors: Alejandra Duran, Isabelle Runkle, Pilar Matía, Maria P de Miguel, Sofia Garrido, Emilio Cervera, Maria D Fernandez, Pilar Torres, Tomas Lillo, Patricia Martin, Lucio Cabrerizo, Nuria Garcia de la Torre, Jose R Calle, Jose Ibarra, Aniceto L Charro and Alfonso L Calle-Pascual

    Citation: BMC Endocrine Disorders 2008 8:9

    Content type: Research article

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  27. Latent autoimmune diabetes in adults [LADA] is a type 1 diabetes that is slowly developing. This means many people are treated as having type 2 diabetes at diagnosis as they are adults who are not immediately ...

    Authors: Sinead Brophy, Helen Davies, Stephen Bain, Jeffrey W Stephens, Wei-yee Cheung, Kez Richards, Kathie Wareham, Charles Beaverstock, Janet Lloyd, Don Page, Meurig Williams, Ian Russell and Rhys Williams

    Citation: BMC Endocrine Disorders 2008 8:8

    Content type: Study protocol

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  28. In Andalusia there were no studies including a representative sample of children and adolescent population assessing growth and weight increase. Our objectives were to develop reference standards for weight, h...

    Authors: Juan Pedro López-Siguero, Juan Manuel Fernández García, Juan de Dios Luna Castillo, Jose Antonio Moreno Molina, Carlos Ruiz Cosano and Antonio Jurado Ortiz

    Citation: BMC Endocrine Disorders 2008 8(Suppl 1):S1

    Content type: Research

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    This article is part of a Supplement: Volume 8 Supplement 1

  29. The number of people with cardiovascular disease (CVD) and diabetes mellitus type 2 (T2DM) is growing rapidly. To a large extend, this increase is due to lifestyle-dependent risk factors, such as overweight, r...

    Authors: Jeroen Lakerveld, Sandra DM Bot, Marijke J Chinapaw, Maurits W van Tulder, Patricia van Oppen, Jacqueline M Dekker and Giel Nijpels

    Citation: BMC Endocrine Disorders 2008 8:6

    Content type: Study protocol

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  30. Accurate identification of hypoglycemia cases by International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) codes will help to describe epidemiology, monitor trends, and propose in...

    Authors: Adit A Ginde, Phillip G Blanc, Rebecca M Lieberman and Carlos A Camargo Jr

    Citation: BMC Endocrine Disorders 2008 8:4

    Content type: Research article

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  31. Insulin resistance and diabetes are associated with increased oxidative stress and impairment of cellular defence systems. Our purpose was to investigate the interaction between glucose metabolism, antioxidati...

    Authors: Mika Venojärvi, Sirkka Aunola, Raivo Puhke, Jukka Marniemi, Helena Hämäläinen, Jukka-Pekka Halonen, Jaana Lindström, Merja Rastas, Kirsti Hällsten, Pirjo Nuutila, Osmo Hänninen and Mustafa Atalay

    Citation: BMC Endocrine Disorders 2008 8:3

    Content type: Research article

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  32. Thyroid physiology is closely related to oxidative changes. The aim of this controlled study was to evaluate the levels of nutritional anti-oxidants such as vitamin C, zinc (Zn) and selenium (Se), and to inves...

    Authors: Roy Moncayo, Alexander Kroiss, Manfred Oberwinkler, Fatih Karakolcu, Matthias Starzinger, Klaus Kapelari, Heribert Talasz and Helga Moncayo

    Citation: BMC Endocrine Disorders 2008 8:2

    Content type: Research article

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  33. Because of the possible role of cytokines including interleukins (IL) in systemic non-thyroidal illnesses' (NTI) pathogenesis and consequently the frequently associated alterations in thyroid hormone (TH) conc...

    Authors: Hamdy A Abo-Zenah, Sabry A Shoeb, Alaa A Sabry and Hesham A Ismail

    Citation: BMC Endocrine Disorders 2008 8:1

    Content type: Research article

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  34. Studies have shown that metabolic syndrome and its consequent biochemical derangements in the various phases of diabetes may contribute to carcinogenesis. A part of this carcinogenic effect could be attributed...

    Authors: K Harish, M Dharmalingam and M Himanshu

    Citation: BMC Endocrine Disorders 2007 7:10

    Content type: Study protocol

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  35. Persons of Pakistani origin living in Oslo have a much higher prevalence of vitamin D deficiency and secondary hyperparathyroidism but similar bone mineral density compared with ethnic Norwegians. Our objectiv...

    Authors: Kristin Holvik, Haakon E Meyer, Anne Johanne Søgaard, Egil Haug and Jan A Falch

    Citation: BMC Endocrine Disorders 2007 7:9

    Content type: Research article

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  36. Altered levels of erythrocyte Na+K+-ATPase, atherogenic and anti-atherogenic lipid metabolites have been implicated in diabetic complications but their pattern of interactions remains poorly understood.

    Authors: Bamidele A Iwalokun and Senapon O Iwalokun

    Citation: BMC Endocrine Disorders 2007 7:7

    Content type: Research article

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  37. Self management is the cornerstone of effective preventive care in diabetes. Educational interventions that provide self-management skills for people with diabetes have been shown to reduce blood glucose conce...

    Authors: Jyothis T George, Abel Peña Valdovinos, Jonathan C Thow, Ian Russell, Paul Dromgoole, Sarah Lomax, David J Torgerson and Tony Wells

    Citation: BMC Endocrine Disorders 2007 7:6

    Content type: Study protocol

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  38. Basal TSH levels reflect the metabolic status of thyroid function, however the definition and interpretation of the basal levels of TSH is a matter of controversial debate. The aim of this study was to evaluat...

    Authors: Helga Moncayo, Otto Dapunt and Roy Moncayo

    Citation: BMC Endocrine Disorders 2007 7:5

    Content type: Research article

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  39. Annual surveillance (with thyroid function testing) is widely recommended for the long-term follow-up of treated hypothyroid patients. It is based largely on consensus opinion and there is limited evidence to ...

    Authors: Ananth K Viswanath, Alison Avenell, Sam Philip, Shamsunder H Acharya, Graeme MacLennan, Katherine Dalziel, Olivia Pereira, Shirley A Copland, John S Bevan and Prakash Abraham

    Citation: BMC Endocrine Disorders 2007 7:4

    Content type: Research article

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  40. Cycloset™ is a quick-release formulation of bromocriptine mesylate, a dopamine agonist, which in animal models of insulin resistance and type 2 diabetes acts centrally to reduce resistance to insulin- mediated...

    Authors: Richard E Scranton, J Michael Gaziano, Dean Rutty, Michael Ezrokhi and Anthony Cincotta

    Citation: BMC Endocrine Disorders 2007 7:3

    Content type: Study protocol

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  41. Clinical determination of mid-parental height is an important part of the assessment of a child's growth, however our clinical impression has been that parents cannot be relied upon to accurately report their ...

    Authors: Ieva Braziuniene, Thomas A Wilson and Andrew H Lane

    Citation: BMC Endocrine Disorders 2007 7:2

    Content type: Research article

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  42. Variants of uncoupling protein genes UCP1 and UCP2 have been associated with a range of traits. We wished to evaluate contributions of known UCP1 and UCP2 variants to metabolic traits in the Insulin Resistance an...

    Authors: Michèle M Sale, Fang-Chi Hsu, Nicholette D Palmer, Candace J Gordon, Keith L Keene, Hermina M Borgerink, Arun J Sharma, Richard N Bergman, Kent D Taylor, Mohammed F Saad and Jill M Norris

    Citation: BMC Endocrine Disorders 2007 7:1

    Content type: Research article

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  43. Secondary involvement of the thyroid gland is rare. Often the origin of the tumor is difficult to identify from the material obtained by fine-needle aspiration cytology. Renal cell carcinoma of the clear-cell ...

    Authors: Maria João M Bugalho, Evelina Mendonça, Patrícia Costa, Jorge Rosa Santos, Eduardo Silva, Ana Luísa Catarino and Luís G Sobrinho

    Citation: BMC Endocrine Disorders 2006 6:6

    Content type: Case report

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  44. Recombinant human growth hormone (r-hGH) is used to treat: growth hormone deficiency in children and adults; children born small for gestational age; Turner's syndrome; and chronic renal failure. r-hGH is admi...

    Authors: Hervé Dumas, Paris Panayiotopoulos, Dorothy Parker and Vincent Pongpairochana

    Citation: BMC Endocrine Disorders 2006 6:5

    Content type: Research article

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  45. The major cause of primary hypothyroidism is autoimmune mediated with progressive and permanent destruction of the thyroid gland resulting in life-long replacement therapy. Treatable and reversible hypothyroid...

    Authors: Huy A Tran

    Citation: BMC Endocrine Disorders 2006 6:3

    Content type: Case report

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