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Reproductive and Adrenal

This section concerns disorders pertaining to reproductive system and adrenal glands; Articles concerning prevention, diagnosis and management, as well as related molecular genetics, and physiology are considered within this section.

  1. Variants of chromodomain helicase DNA binding protein 7 (CHD7) gene are commonly associated with Kallmann syndrome (KS) and account for 5–6% of idiopathic hypogonadotropic hypogonadism (IHH) cases. Here we rep...

    Authors: Weiwei Xu, Weibin Zhou, Haiyang Lin, Dan Ye, Guoping Chen, Fengqin Dong and Jianguo Shen

    Citation: BMC Endocrine Disorders 2021 21:193

    Content type: Case report

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  2. Obesity is associated with the development of polycystic ovary syndrome (PCOS) and contributes substantially to metabolic abnormalities in women with PCOS. The study aimed to describe and compare the practices...

    Authors: Ruilin Ma, Ying Zou, Wei Wang, Qingmei Zheng, Ying Feng, Han Dong, Zhangyun Tan, Xiaoqin Zeng, Yinqing Zhao, Yan Deng, Yanfang Wang and Aijun Sun

    Citation: BMC Endocrine Disorders 2021 21:182

    Content type: Research article

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  3. Various adrenal disorders including primary aldosteronism and Cushing’s syndrome lead to the cause of hypertension. Although primary aldosteronism is sometimes complicated with preclinical Cushing’s syndrome, ...

    Authors: Yoshiro Fushimi, Fuminori Tatsumi, Junpei Sanada, Masashi Shimoda, Shinji Kamei, Shuhei Nakanishi, Kohei Kaku, Tomoatsu Mune and Hideaki Kaneto

    Citation: BMC Endocrine Disorders 2021 21:163

    Content type: Case report

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  4. Despite strong evidence demonstrating the role of estrogen as a protective factor for kidney function in women, limited data are available regarding the influence of endogenous estrogen exposure (EEE) on chron...

    Authors: Maryam Farahmand, Fahimeh Ramezani Tehrani, Davood Khalili, Leila Cheraghi and Fereidoun Azizi

    Citation: BMC Endocrine Disorders 2021 21:155

    Content type: Research article

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  5. Vaginal paraganglioma are rare, atypical, solitary tumors which originate from the female genital tract. Sacrococcygeal teratoma are also rare neoplasms which derive from one (or more) primordial germ cell lay...

    Authors: Zhan Wang, Hua Fan, Jinghua Fan, Samuel Seery, Wenda Wang and Yushi Zhang

    Citation: BMC Endocrine Disorders 2021 21:145

    Content type: Case report

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  6. Non-alcoholic fatty liver disease (NAFLD) is a common disorder that is known to be the leading cause of chronic liver disease worldwide. This study aims to systematically review and meta-analyze the associatio...

    Authors: Nader Salari, Niloufar Darvishi, Kamran Mansouri, Hooman Ghasemi, Melika Hosseinian-Far, Fateme Darvishi and Masoud Mohammadi

    Citation: BMC Endocrine Disorders 2021 21:125

    Content type: Research article

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  7. Previous studies have indicated that women with a history of menstrual disorders have an increased risk of metabolic and cardiovascular diseases. This has been attributed to the high proportion of polycystic o...

    Authors: Saisai Li, Linjuan Ma, Yang Song, Jiehong Zheng, Yuqun Cai, Hong Xu, Peiqiong Chen, Wenxian Xu, Yizhou Huang, Tongyun Qi, Chunming Li, Ketan Chu, Yibing Lan, Ling Xu and Jianhong Zhou

    Citation: BMC Endocrine Disorders 2021 21:121

    Content type: Research article

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  8. Most patients with congenital adrenal hypoplasia (AHC) develop symptoms during infantile and juvenile periods, with varying clinical manifestations. AHC is a disease that is easily misdiagnosed as Addison’s di...

    Authors: Hong Ouyang, Bo Chen, Na Wu, Ling Li, Runyu Du, Meichen Qian, Wenshu Yu, Yujing He and Xinyan Liu

    Citation: BMC Endocrine Disorders 2021 21:118

    Content type: Case report

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  9. The purpose of this study was to investigate the application value of serum 25(OH)D3, uric acid, triglyceride (TG), and homeostasis model assessment of insulin resistance (HOMA-IR) in male patients with hyperu...

    Authors: Qun Zhang, Wei Chen, Canqin Yun and Juan Wang

    Citation: BMC Endocrine Disorders 2021 21:102

    Content type: Research article

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  10. Polycystic ovarian syndrome (PCOS) is the most common endocrinopathy among young women. Insulin resistance is a key feature in the pathogenesis of PCOS; also high molecular weight adiponectin is a marker of in...

    Authors: Farnaz Kamali Haghighi Shirazi, Zohre Khodamoradi and Marjan Jeddi

    Citation: BMC Endocrine Disorders 2021 21:45

    Content type: Research article

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  11. Adrenal vein sampling (AVS) is the preferred method for subtyping patients with primary aldosteronism, while the procedure is technically challenging. This study evaluated the feasibility and effectiveness of ...

    Authors: Jindong Wan, Fei Ran, Siwei Xia, Jixin Hou, Dan Wang, Sen Liu, Yi Yang, Peng Zhou and Peijian Wang

    Citation: BMC Endocrine Disorders 2021 21:22

    Content type: Research article

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  12. Plasma aldosterone-to-renin ratio (ARR) is popularly used for screening primary aldosteronism (PA). Some medications, including diuretics, are known to have an effect on ARR and cause false-negative and false-...

    Authors: Toshitaka Sawamura, Shigehiro Karashima, Satoshi Nagase, Hidetaka Nambo, Eiko Shimizu, Takuya Higashitani, Daisuke Aono, Azusa Ohbatake, Mitsuhiro Kometani, Masashi Demura, Kenji Furukawa, Yoshiyu Takeda and Takashi Yoneda

    Citation: BMC Endocrine Disorders 2020 20:177

    Content type: Research article

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  13. Congenital adrenal hyperplasia (CAH) is an autosomal recessive group of diseases. 21-Hydroxylase deficiency (21OHD) accounts for between 95 and 99% of all CAH cases.

    Authors: Tania Mayvel Espinosa Reyes, Teresa Collazo Mesa, Paulina Arasely Lantigua Cruz, Adriana Agramonte Machado, Emma Domínguez Alonso and Henrik Falhammar

    Citation: BMC Endocrine Disorders 2020 20:165

    Content type: Research article

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  14. Congenital adrenal hyperplasia (CAH) with 17α-hydroxylase deficiency is a rare disease; patients often require lifetime cortisol treatment. In this case report, we presented a patient with CAH and 17α-hydroxyl...

    Authors: Chenyu Xiang, Minmin Han, Yi Zhang, Jianhong Yin, Li’e Pei, Jing Yang and Yunfeng Liu

    Citation: BMC Endocrine Disorders 2020 20:144

    Content type: Case report

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  15. Plasma renin activity (PRA) is generally increased in patients with pheochromocytoma (PCC) due to low circulating plasma volume and activation of β-1 adrenergic receptor signaling. However, there has been no s...

    Authors: Tomoko Yamada, Hidenori Fukuoka, Yusei Hosokawa, Yukiko Odake, Kenichi Yoshida, Ryusaku Matsumoto, Hironori Bando, Yuko Okada, Yushi Hirota, Genzo Iguchi, Wataru Ogawa and Yutaka Takahashi

    Citation: BMC Endocrine Disorders 2020 20:140

    Content type: Research article

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  16. Sympathetic activity and insulin resistance have recently been linked with chronic tendon and musculoskeletal pain. Polycystic ovarian syndrome is linked with insulin resistance and increased sympathetic drive...

    Authors: Jacob Jewson, Elisabeth Lambert, Carolina Sari, Eveline Jona, Soulmaz Shorakae, Gavin Lambert and Jamie Gaida

    Citation: BMC Endocrine Disorders 2020 20:131

    Content type: Research article

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  17. Primary aldosteronism (PA) increases the risk of cardiovascular morbidity, including stroke, coronary artery disease, atrial fibrillation, and heart failure. The relationship between primary aldosteronism and ...

    Authors: Ying Zhang, Fang Luo, Peng Fan, Xu Meng, Kunqi Yang and Xianliang Zhou

    Citation: BMC Endocrine Disorders 2020 20:115

    Content type: Case report

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  18. We investigated whether the contralateral suppression index in aldosterone-producing adrenal adenoma could be used as a diagnostic criterion when catheterization in either right or left adrenal vein fails or w...

    Authors: Jeongmin Lee, Borami Kang, Jeonghoon Ha, Min-Hee Kim, Byungil Choi, Tae-Ho Hong, Moo IL Kang and Dong-Jun Lim

    Citation: BMC Endocrine Disorders 2020 20:114

    Content type: Research article

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