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Epidemiology of Endocrine Disorders

Section edited by Stavros Liatis

This section concerns all aspects of the epidemiology of endocrine disorders including but not limited to: cohort studies, genetic association studies, and prevalence studies.

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  1. Content type: Research article

    Random glucose is widely measured in epidemiological studies and in the clinical setting when standardized fasting protocols and oral glucose tolerance testing or HbA1c measuring are not feasible. The relationshi...

    Authors: Jens Baumert, Christin Heidemann, Rebecca Paprott, Yong Du and Christa Scheidt-Nave

    Citation: BMC Endocrine Disorders 2018 18:95

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  2. Content type: Research article

    Proinsulin connecting peptide (C-Peptide) is a marker of the beta-cell function and has been considered a marker of insulin resistance whose evidence suggests were associated with cardiovascular mortality. Our...

    Authors: Romildo Luiz Monteiro Andrade, Denise P. Gigante, Isabel Oliveira de Oliveira and Bernardo Lessa Horta

    Citation: BMC Endocrine Disorders 2018 18:80

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  3. Content type: Study protocol

    Subclinical hypothyroidism is common in older people and its contribution to health and disease needs to be elucidated further. Observational and clinical trial data on the clinical effects of subclinical hypo...

    Authors: R. S. Du Puy, I. Postmus, D. J. Stott, M. R. Blum, R. K. E. Poortvliet, W. P. J. Den Elzen, R. P. Peeters, B. C. van Munster, B. H. R. Wolffenbuttel, R. G. J. Westendorp, P. M. Kearney, I. Ford, S. Kean, C. M. Messow, T. Watt, J. W. Jukema…

    Citation: BMC Endocrine Disorders 2018 18:67

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  4. Content type: Research article

    Insulin and insulin-like growth factor (IGF)-1 coupled with growth hormone helps control timing of sexual maturation. Mutations and variants in multiple genes are associated with development or reduced risk of...

    Authors: Hua-Pin Chang, Shun-Fa Yang, Shu-Li Wang and Pen-Hua Su

    Citation: BMC Endocrine Disorders 2018 18:66

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  5. Content type: Research article

    To investigate the effect of a mildly elevated thyroid-stimulating hormone (TSH) concentration between 2.5 and 4.0 mIU/L during the first trimester on pregnancy outcomes in thyroid peroxydase antibody (TPOAb)-...

    Authors: Ping Li, Shuo Lin, Ling Li, Jinhui Cui, Shuisheng Zhou and Jianhui Fan

    Citation: BMC Endocrine Disorders 2018 18:64

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  6. Content type: Research article

    Vitamin D deficiency is pandemic while resources available to measure 25-hydroxyvitamin D (25OHD) are limited. The present study aimed to verify whether sun exposure measured by a structured questionnaire coul...

    Authors: Fernanda Barros Bittar, Charlles H. M. Castro and Vera Lúcia Szejnfeld

    Citation: BMC Endocrine Disorders 2018 18:44

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  7. Content type: Research article

    Diabetic foot is one of the most significant and devastating complication of diabetes. The objective of this study was to assess the prevalence of diabetic foot syndrome (DFS) and the associated risk factors a...

    Authors: S. P. Vibha, Muralidhar M. Kulkarni, A. B. Kirthinath Ballala, Asha Kamath and G. Arun Maiya

    Citation: BMC Endocrine Disorders 2018 18:43

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  8. Content type: Research article

    Obesity and diabetes mellitus, or diabetes, are independently associated with post-ischemic stroke outcomes (e.g., functional disability and all-cause mortality). Although obesity and diabetes are also associated...

    Authors: Colleen Bauza, Sharon D. Yeatts, Keith Borg, Gayenell Magwood, Renee’ H. Martin, Anbesaw Selassie and Marvella E. Ford

    Citation: BMC Endocrine Disorders 2018 18:40

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  9. Content type: Research article

    Screening for risk of type 2 diabetes mellitus (T2DM) is an important public health issue. Previous studies report that fasting plasma glucose (FPG) and triglyceride (TG)-related indices, such as lipid accumul...

    Authors: Joung-Won Lee, Nam-Kyoo Lim and Hyun-Young Park

    Citation: BMC Endocrine Disorders 2018 18:33

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  10. Content type: Research article

    Thyroid hormones are known to have direct and indirect effects on metabolism. Individuals with metabolic syndrome, a disease that is growing in incidence at a rapid rate, are at higher risk for cardiovascular ...

    Authors: Jieun Jang, Youngsook Kim, Jaeyong Shin, Sang Ah Lee, Young Choi and Eun-Cheol Park

    Citation: BMC Endocrine Disorders 2018 18:29

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  11. Content type: Research article

    Recent epidemiological studies have suggested inverse associations between vitamin D status and metabolic diseases including type 2 diabetes (T2DM). The aim of this study was to examine whether a higher serum ...

    Authors: Danting Li, Haoche Wei, Hongmei Xue, Jieyi Zhang, Mengxue Chen, Yunhui Gong and Guo Cheng

    Citation: BMC Endocrine Disorders 2018 18:25

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  12. Content type: Research article

    The aim of this study was to quantify the association of Val109Asp polymorphism of intelectin 1 (ITLN1) gene with the abdominal obesity (AO) in Kyrgyz population.

    Authors: Jainagul Isakova, Elnura Talaibekova, Denis Vinnikov, Nazira Aldasheva, Erkin Mirrakhimov and Almaz Aldashev

    Citation: BMC Endocrine Disorders 2018 18:15

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  13. Content type: Research article

    Many studies have reported associations between estrogen receptor (ER) gene polymorphisms and postmenopausal osteoporosis (PMOP) risk and bone mineral density (BMD), but the results are controversial. The aim ...

    Authors: Heping Zhu, Jiannong Jiang, Qiang Wang, Jun Zong, Liang Zhang, Tieliang Ma, Youjia Xu and Leiyan Zhang

    Citation: BMC Endocrine Disorders 2018 18:11

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  14. Content type: Research article

    Although current beta cell replacement therapy is effective in stabilizing glycemic control in highly selected patients with refractory type 1 diabetes, many hurdles are inherent to this and other donor-based ...

    Authors: Klemens Wallner, Rene G. Pedroza, Isaac Awotwe, James M. Piret, Peter A. Senior, A. M. James Shapiro and Christopher McCabe

    Citation: BMC Endocrine Disorders 2018 18:6

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  15. Content type: Research article

    The association between thyroid nodules and adiposity remains controversial. We performed a cross-sectional, community-based study to examine whether thyroid nodules are associated with overweight and obesity,...

    Authors: Bin Song, Zhihua Zuo, Juan Tan, Jianjin Guo, Weiping Teng, Yibing Lu and Chao Liu

    Citation: BMC Endocrine Disorders 2018 18:3

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  16. Content type: Research article

    We investigated how four aspects of socio-demography influence the effectiveness of an intervention with structured personal diabetes care on long-term outcomes.

    Authors: Andreas Heltberg, Volkert Siersma, John Sahl Andersen, Christina Ellervik, Henrik Brønnum-Hansen, Jakob Kragstrup and Niels de Fine Olivarius

    Citation: BMC Endocrine Disorders 2017 17:75

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  17. Content type: Research article

    The metabolic syndrome (MetS) is a combination of unfavourable health factors which includes abdominal obesity, dyslipidaemia, elevated blood pressure and impaired fasting glucose. Earlier studies have reporte...

    Authors: Bruce H. R. Wolffenbuttel, Hanneke J. C. M. Wouters, Sandra N. Slagter, Robert P. van Waateringe, Anneke C. Muller Kobold, Jana V. van Vliet-Ostaptchouk, Thera P. Links and Melanie M. van der Klauw

    Citation: BMC Endocrine Disorders 2017 17:65

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  18. Content type: Research article

    Adrenal crisis (AC) occurs in various clinical conditions but previous epidemiological studies in AC are limited to chronic adrenal insufficiency (AI) and sepsis. The aim of this study was to investigate chara...

    Authors: Masahiro Iwasaku, Maki Shinzawa, Shiro Tanaka, Kimihiko Kimachi and Koji Kawakami

    Citation: BMC Endocrine Disorders 2017 17:58

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  19. Content type: Research article

    The increasing prevalence of diabetes is leading to a rise of eye diseases, augmenting the risk of sight-threatening complications. The aim of this study was to evaluate prevalence, awareness and practices reg...

    Authors: Lazaros Konstantinidis, Tania Carron, Eva de Ancos, Léonie Chinet, Isabelle Hagon-Traub, Emilie Zuercher and Isabelle Peytremann-Bridevaux

    Citation: BMC Endocrine Disorders 2017 17:56

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  20. Content type: Research article

    Acromegaly is a rare, slowly progressive disorder resulting from excessive growth hormone (GH) production by a pituitary somatotroph tumor. The objective of this study was to examine acromegaly treatment outco...

    Authors: John D. Carmichael, Michael S. Broder, Dasha Cherepanov, Eunice Chang, Adam Mamelak, Qayyim Said, Maureen P. Neary and Vivien Bonert

    Citation: BMC Endocrine Disorders 2017 17:49

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  21. Content type: Research article

    Gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) are the most common type of neuroendocrine tumors, accounting for more than half of neuroendocrine neoplasms (NENs). We performed a retrospective stud...

    Authors: Meng Zhang, Ping Zhao, Xiaodan Shi, Ahong Zhao, Lianfeng Zhang and Lin Zhou

    Citation: BMC Endocrine Disorders 2017 17:39

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  22. Content type: Research article

    Used the EuroQoL-5 dimension (EQ-5D) to evaluate the health status of 5310 residents who live in East China, and compared the health-related quality of life (HRQoL) with 311 patients with type 2 diabetes as we...

    Authors: You Lu, Ningjian Wang, Yi Chen, Xiaomin Nie, Qin Li, Bing Han, Yingchao Chen, Fangzhen Xia, Zhen Cang, Meng Lu, Ying Meng and Yingli Lu

    Citation: BMC Endocrine Disorders 2017 17:38

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  23. Content type: Research article

    Persistent diabetes-related distress (DRD) is experienced by patients with Type 2 Diabetes Mellitus. Knowing factors associated with persistent DRD will aid clinicians in prioritising interventions efforts.

    Authors: Maudrene L. Tan, Chuen S. Tan, Konstadina Griva, Yung S. Lee, Jeannette Lee, E. S. Tai, Eric Y. Khoo and Hwee-Lin Wee

    Citation: BMC Endocrine Disorders 2017 17:36

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  24. Content type: Research article

    Patients with type 2 diabetes mellitus (T2DM) may develop color vision impairment. This study aimed to determine the prevalence and factors associated with impaired color vision in patients with T2DM but witho...

    Authors: N. C. Tan, W. F. Yip, S. Kallakuri, U. Sankari and Y. L. E. Koh

    Citation: BMC Endocrine Disorders 2017 17:29

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  25. Content type: Research article

    The epidemic rise of diabetes carries major negative public health and economic consequences particularly for low and middle-income countries. The highest predicted percentage growth in diabetes is in the sub-...

    Authors: Andrew Bastawrous, Wanjiku Mathenge, Kevin Wing, Madeleine Bastawrous, Hillary Rono, Helen A. Weiss, David Macleod, Allen Foster, Tunde Peto, Peter Blows, Matthew Burton and Hannah Kuper

    Citation: BMC Endocrine Disorders 2017 17:19

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  26. Content type: Research article

    Associations between lung function and non-alcoholic fatty liver disease (NAFLD) have been reported. However, evidence from large-scale populations about the relationship is scarce. The objective of the study ...

    Authors: Li Qin, Weiwei Zhang, Zhen Yang, Yixin Niu, Xiaoyong Li, Shuai Lu, Yin Xing, Ning Lin, Hongmei Zhang, Guang Ning, Jiangao Fan and Qing Su

    Citation: BMC Endocrine Disorders 2017 17:18

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  27. Content type: Research article

    The prevalence of erectile dysfunction among diabetic men varies between 35–90%. Although erectile dysfunction is widespread among men with diabetes, the condition often remains undiagnosed and demands appropr...

    Authors: Awole Seid, Hadgu Gerensea, Shambel Tarko, Yosef Zenebe and Rahel Mezemir

    Citation: BMC Endocrine Disorders 2017 17:16

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  28. Content type: Research article

    The study aim was to estimate the proportion of acromegaly patients with various comorbidities and to determine if biochemical control was associated with reduced proportion of cardiovascular risk factors.

    Authors: John D. Carmichael, Michael S. Broder, Dasha Cherepanov, Eunice Chang, Adam Mamelak, Qayyim Said, Maureen P. Neary and Vivien Bonert

    Citation: BMC Endocrine Disorders 2017 17:15

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  29. Content type: Research article

    Sleep disorders are common and associated with multiple metabolic and psychological derangements. Obstructive sleep apnoea (OSA) is among the most common sleep disorders and an inter-relationship between OSA, ...

    Authors: Sairabanu Mohammed Rashid Sokwalla, Mark David Joshi, Erastus Olonde Amayo, Kirtida Acharya, Jared Ongechi Mecha and Kenneth Kipyegon Mutai

    Citation: BMC Endocrine Disorders 2017 17:7

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  30. Content type: Study protocol

    Subclinical hypothyroidism (SCH) is a common condition in elderly people, defined as elevated serum thyroid-stimulating hormone (TSH) with normal circulating free thyroxine (fT4). Evidence is lacking about the...

    Authors: David J. Stott, Jacobijn Gussekloo, Patricia M. Kearney, Nicolas Rodondi, Rudi G. J. Westendorp, Simon Mooijaart, Sharon Kean, Terence J. Quinn, Naveed Sattar, Kirsty Hendry, Robert Du Puy, Wendy P. J. Den Elzen, Rosalinde K. E. Poortvliet, Jan W. A. Smit, J. Wouter Jukema, Olaf M. Dekkers…

    Citation: BMC Endocrine Disorders 2017 17:6

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  31. Content type: Research article

    Factual data exploring the relationship between obesity and diabetes mellitus prevalence from rural areas of sub-Saharan Africa remain scattered and are unreliable. To address this scarceness, this work report...

    Authors: Philippe Bianga Katchunga, Justin Cikomola, Christian Tshongo, Arsene Baleke, David Kaishusha, Patrick Mirindi, Théodore Tamburhe, Yves Kluyskens, Antoine Sadiki, Socrate Bwanamudogo, Zacharie Kashongwe and Marc Twagirumukiza

    Citation: BMC Endocrine Disorders 2016 16:60

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  32. Content type: Research article

    Diabetes and hypertension increase arterial stiffness and cardiovascular events in all societies studied so far; sub-Saharan African studies are sparse. We investigated factors affecting arterial function in G...

    Authors: Kwame Yeboah, Daniel A. Antwi, Ben Gyan, Virginia Govoni, Charlotte E. Mills, J. Kennedy Cruickshank and Albert G. B. Amoah

    Citation: BMC Endocrine Disorders 2016 16:53

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  33. Content type: Research article

    Twins may be at increased risk of dysglycaemic disorders due to adverse fetal conditions. Data from Africa regarding this association is limited. We studied impaired glucose tolerance (IGT) and other types of ...

    Authors: Ditte Egegaard Hennild, Morten Bjerregaard-Andersen, Luis Carlos Joaquím, Kaare Christensen, Morten Sodemann, Henning Beck-Nielsen and Dorte Møller Jensen

    Citation: BMC Endocrine Disorders 2016 16:46

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  34. Content type: Research article

    There is a scarcity of epidemiological researches examining the relationship between blood pressure (BP) and glucose level among older adults. The objective of the current study was to investigate the associat...

    Authors: Qun Yan, Dongmei Sun, Xu Li, Guoliang Chen, Qinghu Zheng, Lun Li, Chenhong Gu and Bo Feng

    Citation: BMC Endocrine Disorders 2016 16:40

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  35. Content type: Research article

    The provision of health education involving self-care and good adherence to medications has been acknowledged to be a cost effective strategy for improving quality of life of diabetes patients. We assessed lev...

    Authors: Tefera Kassahun, Hailay Gesesew, Lillian Mwanri and Tesfahun Eshetie

    Citation: BMC Endocrine Disorders 2016 16:28

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  36. Content type: Research article

    Associations between metabolic syndrome (MetS) and osteoporotic fracture have been reported. However, the epidemiological studies are not conclusive. The objective of the study was to determine whether metabol...

    Authors: Li Qin, Zhen Yang, Weiwei Zhang, Hongxia Gu, Xiaoyong Li, Lingfei Zhu, Shuai Lu, Yin Xing, Hongmei Zhang, Yixin Niu, Guang Ning and Qing Su

    Citation: BMC Endocrine Disorders 2016 16:27

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  37. Content type: Research article

    Prevalence of diabetes and cardiovascular (CVD) disease amongst UK South Asians is higher than in the general population. Non-adherence to medicines may lead to poor clinical outcomes for South Asian patients ...

    Authors: Kanta Kumar, Sheila Greenfield, Karim Raza, Paramjit Gill and Rebecca Stack

    Citation: BMC Endocrine Disorders 2016 16:24

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  38. Content type: Research article

    Islet cell transplantation is a method to stabilize type 1 diabetes patients with hypoglycemia unawareness and unstable blood glucose levels by reducing insulin dependency and protecting against severe hypogly...

    Authors: Klemens Wallner, A. M. James Shapiro, Peter A. Senior and Christopher McCabe

    Citation: BMC Endocrine Disorders 2016 16:17

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  39. Content type: Research article

    The relationship between alterations in thyroid function and cognitive deficits has been investigated in several previous studies. Hypo-or hyperthyroidism and, to a lesser extent, subclinical thyroid dysfuncti...

    Authors: Yao Hu, Zhi-cheng Wang, Qi-hao Guo, Wei Cheng and Yan-wen Chen

    Citation: BMC Endocrine Disorders 2016 16:11

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  40. Content type: Research article

    Experiments in mice initially suggested a role for the protein angiopoietin-like 8 (ANGPTL8) in glucose homeostasis. However, subsequent experiments in model systems have challenged this proposed role. We soug...

    Authors: Katharine R. Clapham, Audrey Y. Chu, Jennifer Wessel, Pradeep Natarajan, Jason Flannick, Manuel A. Rivas, Samantha Sartori, Roxana Mehran, Usman Baber, Valentin Fuster, Robert A. Scott, Daniel J. Rader, Michael Boehnke, Mark I. McCarthy, David M. Altshuler, Sekar Kathiresan…

    Citation: BMC Endocrine Disorders 2016 16:7

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  41. Content type: Research article

    Primary hyperparathyroidism (PHPT) and metabolic syndrome (MS) have been independently related to cardiovascular morbidities, however this association is still controversial. Mexican population has a high prev...

    Authors: Victoria Mendoza-Zubieta, Gloria A Gonzalez-Villaseñor, Guadalupe Vargas-Ortega, Baldomero Gonzalez, Claudia Ramirez-Renteria, Moises Mercado, Mario A Molina-Ayala and Aldo Ferreira-Hermosillo

    Citation: BMC Endocrine Disorders 2015 15:16

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  42. Content type: Study protocol

    Children whose mothers had low thyroid hormone levels during pregnancy have been reported to have decreased cognitive function. The reported research is part of the follow-on study of the Controlled Antenatal ...

    Authors: Charlotte Hales, Sue Channon, Peter N Taylor, Mohd S Draman, Ilaria Muller, John Lazarus, Ruth Paradice, Aled Rees, Dionne Shillabeer, John W Gregory, Colin M Dayan and Marian Ludgate

    Citation: BMC Endocrine Disorders 2014 14:95

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  43. Content type: Research article

    Diabetic peripheral neuropathy (PN) and peripheral vasculopathy (PV) are major causes of foot ulcers in patients with diabetes. The early detection of PN/PV with appropriate health counseling is the best strat...

    Authors: Chia-Mou Lee, Chang-Cheng Chang, Mei-Yu Pan, Chyong-Fang Chang and Mei-Yen Chen

    Citation: BMC Endocrine Disorders 2014 14:89

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  44. Content type: Research article

    Unspecific symptoms often proceed a serious chronic disease condition long before the onset of the disease. The role of an unspecific premonitory symptom (UPMS) pattern as premonitory signs of subsequent type ...

    Authors: Jens Baumert, Christa Meisinger, Karoline Lukaschek, Rebecca Thwing Emeny, Ina-Maria Rückert, Johannes Kruse and Karl-Heinz Ladwig

    Citation: BMC Endocrine Disorders 2014 14:87

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  45. Content type: Research article

    Polycystic Ovary Syndrome (PCOS) is an endocrine-metabolic disorder that affects approximately 6-10% of women of child-bearing age. Although preliminary studies suggest that certain pollutants may act as endoc...

    Authors: Sara J Vagi, Eduardo Azziz-Baumgartner, Andreas Sjödin, Antonia M Calafat, Daniel Dumesic, Leonardo Gonzalez, Kayoko Kato, Manori J Silva, Xiaoyun Ye and Ricardo Azziz

    Citation: BMC Endocrine Disorders 2014 14:86

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  46. Content type: Research article

    The aim of this study was to empirically validate a conceptual framework and elucidate the pathways linking social determinants of health to outcomes in individuals with type 2 diabetes.

    Authors: Rebekah J Walker, Mulugeta Gebregziabher, Bonnie Martin-Harris and Leonard E Egede

    Citation: BMC Endocrine Disorders 2014 14:82

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  47. Content type: Case report

    Familial Hyperparathyroidism (HPT) and Familial benign Hypocalciuric Hypercalcemia (FHH) are the most common causes of hereditary hypercalcemia. FHH has been demonstrated to be caused by inactivating mutations...

    Authors: Eugenio Mastromatteo, Olga Lamacchia, Michela Rosaria Campo, Antonella Conserva, Filomena Baorda, Luigia Cinque, Vito Guarnieri, Alfredo Scillitani and Mauro Cignarelli

    Citation: BMC Endocrine Disorders 2014 14:81

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