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Diabetes and Metabolism

Section edited by Abd Tahrani

This section concerns all aspects of diabetes and metabolic syndrome including but not limited to: prevention, diagnosis and management, as well as related molecular genetics, and pathophysiology.

Page 5 of 6

  1. The concept is now emerging that higher thyroid-stimulating hormone (TSH) and lower thyroid hormone levels within the euthyroid range may adversely affect atherosclerosis. The aim of this study was to investig...

    Authors: Yun Zhang, Ping Lu, Ling Zhang and Xinhua Xiao

    Citation: BMC Endocrine Disorders 2015 15:12

    Content type: Research article

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  2. Insulin resistance triggered by excess fat is a key pathogenic factor that promotes type 2 diabetes. Understanding molecular mechanisms of insulin resistance may lead to the identification of a novel therapeut...

    Authors: Andreas AK Tandelilin, Tetsuaki Hirase, Athanasius W Hudoyo, Jidong Cheng, Keiko Toyama, Hiroko Morisaki and Takayuki Morisaki

    Citation: BMC Endocrine Disorders 2015 15:11

    Content type: Research article

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    The Erratum to this article has been published in BMC Endocrine Disorders 2015 15:80

  3. Insulin resistance (IR) plays a vital role in the pathogenesis of Type 2 Diabetes Mellitus (T2DM). The mechanism of IR may be associated with inflammation, whereas the neutrophil-lymphocyte ratio (NLR) is a ne...

    Authors: Meiqin Lou, Peng Luo, Ru Tang, Yixian Peng, Siyuan Yu, Wanjing Huang and Lei He

    Citation: BMC Endocrine Disorders 2015 15:9

    Content type: Research article

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  4. Diabetic retinopathy (DR) is an important microvascular complication of diabetes with a high concordance rate in patients with diabetes. Inflammation is supposed to participate in the development of DR. This s...

    Authors: Danfeng Peng, Jie Wang, Rong Zhang, Shanshan Tang, Feng Jiang, Miao Chen, Jing Yan, Xue Sun, Tao Wang, Shiyun Wang, Yuqian Bao, Cheng Hu and Weiping Jia

    Citation: BMC Endocrine Disorders 2015 15:8

    Content type: Research article

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  5. Evidence suggests that activation of κ-opioid receptor (KOR) by U50,488H exhibits potential cardiovascular protective properties. However, the effects of U50,488H on vascular dysfunction in diabetes mellitus (...

    Authors: Xuan Zhou, Dongjuan Wang, Yuyang Zhang, Jinxia Zhang, Dingcheng Xiang and Haichang Wang

    Citation: BMC Endocrine Disorders 2015 15:7

    Content type: Research article

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  6. Vitamin D deficiency reportedly is associated with type 2 diabetes (T2DM). We aim to examine whether 25-hydroxyvitamin D (25OHD) has clinically significant influence on hemoglobin glycation (HbA1c) and insulin...

    Authors: Jayesh J Sheth, Ankna Shah, Frenny J Sheth, Sunil Trivedi, Mamta Lele, Navneet Shah, Premal Thakor and Rama Vaidya

    Citation: BMC Endocrine Disorders 2015 15:5

    Content type: Research article

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  7. In the treatment of childhood type 1 diabetes, being aware of the parents’ fear of hypoglycemia is important, since the parents’ fear may influence the management of treatment and the children’s blood glucose ...

    Authors: Anne Haugstvedt, Tore Wentzel-Larsen, Morten Aarflot, Berit Rokne and Marit Graue

    Citation: BMC Endocrine Disorders 2015 15:2

    Content type: Research article

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  8. The study of endogenous insulin secretion may provide relevant insight into the comparison of the natural history of adult onset latent autoimmune diabetes (LADA) with types 1 and 2 diabetes mellitus. The aim ...

    Authors: Marta Hernandez, Angels Mollo, Josep Ramon Marsal, Aureli Esquerda, Ismael Capel, Manel Puig-Domingo, Paolo Pozzilli, Alberto de Leiva and Didac Mauricio

    Citation: BMC Endocrine Disorders 2015 15:1

    Content type: Research article

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  9. Insulin resistance is one of the hallmark manifestations of obesity and Type II diabetes and reversal of this pathogenic abnormality is an attractive target for new therapies for Type II diabetes. A recent rep...

    Authors: Jidong Cheng, Hiroko Morisaki, Keiko Toyama, Naomi Sugimoto, Takuya Shintani, Andreas Tandelilin, Tetsuaki Hirase, Edward W Holmes and Takayuki Morisaki

    Citation: BMC Endocrine Disorders 2014 14:96

    Content type: Research article

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  10. The combined effect of the metabolic syndrome (MS) risk factors on bone health has led to controversial results and it is still not clear whether this effect is protective or detrimental. The study aimed to ex...

    Authors: Abdellah El Maghraoui, Asmaa Rezqi, Salwa El Mrahi, Siham Sadni, Imad Ghozlani and Aziza Mounach

    Citation: BMC Endocrine Disorders 2014 14:93

    Content type: Research article

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  11. In primary health care systems where member’s turnover is relatively low, the question, whether investment in quality of care improvement can make a business case, or is cost effective, has not been fully answ...

    Authors: Rachel Wilf-Miron, Arkadi Bolotin, Nesia Gordon, Avi Porath and Ronit Peled

    Citation: BMC Endocrine Disorders 2014 14:92

    Content type: Research article

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  12. Alterations in postprandial metabolism have been described in familial combined hyperlipidemia (FCH); however, their underlying mechanisms are not well characterized. We aimed to identify factors related to th...

    Authors: Paloma Almeda-Valdes, Daniel Cuevas-Ramos, Roopa Mehta, Liliana Muñoz-Hernandez, Ivette Cruz-Bautista, Oscar Perez-Mendez, Maria Teresa Tusie-Luna, Francisco J Gomez-Perez, Päivi Pajukanta, Niina Matikainen, Marja-Riitta Taskinen and Carlos A Aguilar-Salinas

    Citation: BMC Endocrine Disorders 2014 14:90

    Content type: Research article

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  13. Carpal tunnel syndrome (CTS) is the most common entrapment neuropathy encountered in diabetes. The short-term improvement after carpal tunnel release has previously been demonstrated not to differ between pati...

    Authors: Niels OB Thomsen, Jonas Björk and Ragnhild I Cederlund

    Citation: BMC Endocrine Disorders 2014 14:85

    Content type: Research article

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  14. Diabetes has previously been linked to mental health problems in adolescents, but more recent studies have yielded mixed findings. The aim of the current study was to compare symptoms of mental health problems...

    Authors: Børge Sivertsen, Keith J Petrie, Ane Wilhelmsen-Langeland and Mari Hysing

    Citation: BMC Endocrine Disorders 2014 14:83

    Content type: Research article

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  15. Metabolic syndrome (MetS) is a clustering of metabolic risk factors for cardiovascular diseases and type 2 diabetes. The study aimed to estimate the prevalence of MetS, its components, and their associations a...

    Authors: Tran Quang Binh, Pham Tran Phuong, Bui Thi Nhung and Do Dinh Tung

    Citation: BMC Endocrine Disorders 2014 14:77

    Content type: Research article

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  16. Disturbances of the circadian rhythm of cortisol secretion are associated with depression, coronary calcification, and higher all-cause and cardiovascular mortality.

    Authors: Eva O Melin, Maria Thunander, Mona Landin-Olsson, Magnus Hillman and Hans O Thulesius

    Citation: BMC Endocrine Disorders 2014 14:75

    Content type: Research article

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  17. Although multivitamin products are widely used as dietary supplements to maintain health or as special medical food in certain diseases, the effects of these products were not investigated in diabetes mellitus...

    Authors: Márta Sárközy, Veronika Fekete, Gergő Szűcs, Szilvia Török, Csilla Szűcs, Judit Bárkányi, Zoltán V Varga, Imre Földesi, Csaba Csonka, Csaba Kónya, Tamás Csont and Péter Ferdinandy

    Citation: BMC Endocrine Disorders 2014 14:72

    Content type: Research article

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  18. Multi-morbidity, or the presence of multiple chronic diseases, is a major problem in clinical care and is associated with worse outcomes. Additionally, the presence of mental health conditions, such as depress...

    Authors: Cheryl P Lynch, Mulugeta Gebregziabher, Yumin Zhao, Kelly J Hunt and Leonard E Egede

    Citation: BMC Endocrine Disorders 2014 14:68

    Content type: Research article

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  19. Increasing prevalence of pre-diabetes is an emerging public health problem. Decrease in sweet taste sensitivity which can lead to an increase in sugar intake might be a factor driving them to overt diabetes. T...

    Authors: Sudharshani Wasalathanthri, Priyadarshika Hettiarachchi and Shamini Prathapan

    Citation: BMC Endocrine Disorders 2014 14:67

    Content type: Research article

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  20. Suboptimal vitamin D status is highly prevalent in Northern communities, particularly in those patients with chronic diseases such as diabetes and chronic renal disease. Emerging literature suggests that adher...

    Authors: Diana R Mager, Stephanie T Jackson, Michelle R Hoffmann, Kailash Jindal and Peter A Senior

    Citation: BMC Endocrine Disorders 2014 14:66

    Content type: Study protocol

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  21. We aimed to evaluate the predictive utility of common fasting insulin sensitivity indices, and non-laboratory surrogates [BMI, waist circumference (WC) and waist-to-height ratio (WHtR)] in sub-Saharan Africans...

    Authors: Eugene Sobngwi, Andre-Pascal Kengne, Justin B Echouffo-Tcheugui, Simeon Choukem, Joelle Sobngwi-Tambekou, Eric V Balti, Mark S Pearce, Valentin Siaha, Aissa S Mamdjokam, Valery Effoe, Eric Lontchi-Yimagou, Oliver T Donfack, Barbara Atogho-Tiedeu, Philippe Boudou, Jean-Francois Gautier and Jean-Claude Mbanya

    Citation: BMC Endocrine Disorders 2014 14:65

    Content type: Research article

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  22. The Space GlucoseControl system (SGC) is a nurse-driven, computer-assisted device for glycemic control combining infusion pumps with the enhanced Model Predictive Control algorithm (B. Braun, Melsungen, German...

    Authors: Karin Amrein, Norman Kachel, Heike Fries, Roman Hovorka, Thomas R Pieber, Johannes Plank, Urs Wenger, Barbara Lienhardt and Marco Maggiorini

    Citation: BMC Endocrine Disorders 2014 14:62

    Content type: Research article

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  23. The purpose of this analysis is to evaluate the safety and effectiveness of insulin initiation with once-daily insulin detemir (IDet) or insulin glargine (IGlar) in real-life clinical practice in Turkish patie...

    Authors: Taner Damci, Rifat Emral, Anne Louise Svendsen, Tanzer Balkir and Jiten Vora

    Citation: BMC Endocrine Disorders 2014 14:61

    Content type: Research article

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  24. Besides the classical role of vitamin D on calcium and bone homeostasis, vitamin D deficiency has recently been identified as a contributing factor in the onset of insulin resistance in type 2 diabetes mellitu...

    Authors: Yvonne HM Krul-Poel, Hans van Wijland, Frank Stam, Edwin ten Boekel, Paul Lips and Suat Simsek

    Citation: BMC Endocrine Disorders 2014 14:59

    Content type: Study protocol

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  25. Despite the consistent relationship between serum γ-glutamyltransferase (GGT) and type 2 diabetes (T2D), one unsolved issue is the role of serum GGT in the well-known association between obesity and T2D. This ...

    Authors: Nam Soo Hong, Jeong-Gook Kim, Yu-Mi Lee, Hyun-Woo Kim, Sin Kam, Keon-Yeop Kim, Ki-Su Kim and Duk-Hee Lee

    Citation: BMC Endocrine Disorders 2014 14:57

    Content type: Research article

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  26. Advanced glycation endproducts (AGEs) contribute to the development of vascular complications of diabetes and have been recently implicated in the pathogenesis of diabetes. Since AGEs are generated within food...

    Authors: Nicole J Kellow, Melinda T Coughlan, Gayle S Savige and Christopher M Reid

    Citation: BMC Endocrine Disorders 2014 14:55

    Content type: Study protocol

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  27. Oral medication for patients with type 2 diabetes mellitus plays an important role in diabetes care and is associated with a high level self-care behavior and self-management. However, poor adherence to diabet...

    Authors: Sunya-Lee Antoine, Dawid Pieper, Tim Mathes and Michaela Eikermann

    Citation: BMC Endocrine Disorders 2014 14:53

    Content type: Research article

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  28. Obesity and gestational diabetes (GDM) in pregnancy are recognized risk factors for adverse outcomes, including cesarean section (CS), macrosomia and preeclampsia. The aim of this study was to investigate the ...

    Authors: Hayfaa A Wahabi, Amel A Fayed, Rasmieh A Alzeidan and Ahmed A Mandil

    Citation: BMC Endocrine Disorders 2014 14:47

    Content type: Research article

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  29. 11 patients were referred to our Molecular Genetics Department at the Royal Devon and Exeter Hospital between 2000-2012 with a physician’s diagnosis of remitting diabetes. Our aim was to identify patients with...

    Authors: Tarig Babiker, Ali J Chakera, Maggie Shepherd and Andrew T Hattersley

    Citation: BMC Endocrine Disorders 2014 14:45

    Content type: Research article

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  30. Previously considered as a disease of the affluent, west or urban people and not of public health importance, diabetes mellitus is increasingly becoming a significant cause of morbidity and mortality in sub-Sahar...

    Authors: Kelias Phiri Msyamboza, Chimwemwe J Mvula and Damson Kathyola

    Citation: BMC Endocrine Disorders 2014 14:41

    Content type: Research article

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  31. Few studies have examined young adults with type 1 diabetes use of health services and the development of vascular complications. As part of the Youth Outreach for Diabetes (YOuR-Diabetes) project, this study ...

    Authors: Steven James, Lin Perry, Robyn Gallagher, Julia Lowe, Janet Dunbabin, Patrick McElduff, Shamasunder Acharya and Katharine Steinbeck

    Citation: BMC Endocrine Disorders 2014 14:39

    Content type: Research article

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  32. Canagliflozin is a sodium glucose co-transporter 2 inhibitor developed for the treatment of patients with type 2 diabetes mellitus (T2DM). The efficacy and safety of canagliflozin were evaluated in patients wi...

    Authors: Alan Sinclair, Bruce Bode, Stewart Harris, Ujjwala Vijapurkar, Cristiana Mayer, Albert Fung, Wayne Shaw, Keith Usiskin, Mehul Desai and Gary Meininger

    Citation: BMC Endocrine Disorders 2014 14:37

    Content type: Research article

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  33. Insulin aspart (IAsp) and its biphasic preparations BIAsp50 and BIAsp70 (containing 50% and 70% IAsp, respectively) have distinct glucose-lowering properties as compared to human insulin (HI). We investigated ...

    Authors: Zhulin Ma, Jens Sandahl Christiansen, Torben Laursen, Chunsen Wu, Torsten Lauritzen, Tina Parkner and Jan Frystyk

    Citation: BMC Endocrine Disorders 2014 14:35

    Content type: Research article

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  34. Diabetes education and self-care remains the cornerstone of diabetes management. There are many structured diabetes modules available in the United Kingdom, Europe and United States of America. Contrastingly, ...

    Authors: Badariah Ahmad, Amutha Ramadas, Quek Kia Fatt and Anuar Zaini Md Zain

    Citation: BMC Endocrine Disorders 2014 14:31

    Content type: Research article

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  35. Continuous intraperitoneal insulin infusion (CIPII) with an implantable pump is a treatment option for patients with type 1 diabetes mellitus (T1DM). Aim of the present study was to describe the long-term cour...

    Authors: Peter R van Dijk, Susan JJ Logtenberg, Klaas H Groenier, Rijk OB Gans, Nanne Kleefstra and Henk JG Bilo

    Citation: BMC Endocrine Disorders 2014 14:30

    Content type: Research article

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  36. The effects of brain natriuretic peptide (BNP) on the risk of cardiovascular disease and atherosclerosis have been studied. However, little information is available regarding peripheral arterial disease (PAD),...

    Authors: Qi-hui Jin, Wan-lan Ye, Huai-hong Chen, Xiao-jun He, Tian-lang Li, Qiang Liu, Liang Zhong, Lei Xu and Chun-mao Han

    Citation: BMC Endocrine Disorders 2014 14:27

    Content type: Research article

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  37. To study hormonal changes associated with severe hyperglycemia in critically ill children and the relationship with prognosis and length of stay in intensive care.

    Authors: Yolanda Ballestero, Jesús López-Herce, Rafael González, Maria José Solana, Jimena del Castillo, Javier Urbano, Marta Botran, Ana García, Nieves López and Jose María Bellón

    Citation: BMC Endocrine Disorders 2014 14:25

    Content type: Research article

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  38. The aim of the present study is to examine the clinical indices related to cardiovascular risk management of Greek patients with type 2 diabetes, before and after the major economic crisis that emerged in the ...

    Authors: Stavros Liatis, Stavroula Papaoikonomou, Asimina Ganotopoulou, Athanasia Papazafiropoulou, Constantinos Dinos, Marios Michail, Apostolos Xilomenos, Andreas Melidonis and Stavros Pappas

    Citation: BMC Endocrine Disorders 2014 14:23

    Content type: Research article

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  39. Due to ongoing rise in need for care for people with chronic diseases and lagging increase in number of care providers, alternative forms of care provision and self-management support are needed. Empowering pa...

    Authors: Yvonne Roelofsen, Steven H Hendriks, Floor Sieverink, Michael van Vugt, Kornelis JJ van Hateren, Frank J Snoek, Maartje de Wit, Rijk OB Gans, Klaas H Groenier, Julia EWC van Gemert-Pijnen, Nanne Kleefstra and Henk JG Bilo

    Citation: BMC Endocrine Disorders 2014 14:22

    Content type: Study protocol

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  40. Many type 2 diabetes mellitus patients face difficulties self-managing their illness, which can lead to high levels of diabetes-related distress. Diabetes distress may be decreased by peer support, as peers un...

    Authors: Lianne de Vries, Amber AWA van der Heijden, Esther van 't Riet, Caroline A Baan, Piet J Kostense, Mieke Rijken, Guy EHM Rutten and Giel Nijpels

    Citation: BMC Endocrine Disorders 2014 14:21

    Content type: Study protocol

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  41. Hyperglycemia induces chromatin remodeling with consequences on differential gene expression in mouse hepatocytes, similar to what occurs during aging. The liver is the central organ for the regulation of gluc...

    Authors: Flávia G Ghiraldini, André B Silveira, Dirk A Kleinjan, Nick Gilbert and Maria Luiza S Mello

    Citation: BMC Endocrine Disorders 2014 14:19

    Content type: Research article

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  42. To compare the safety and efficacy of saxagliptin 2.5 mg twice daily (BID) versus placebo add-on therapy to metformin immediate release (IR) in patients with type 2 diabetes and inadequate glycemic control wit...

    Authors: Judith L White, Patricia Buchanan, Jia Li and Robert Frederich

    Citation: BMC Endocrine Disorders 2014 14:17

    Content type: Research article

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  43. The possible association between metabolic syndrome (MS) and bone mineral density (BMD) has been highlighted recently. However, the exact effects of MS on calcaneal quantitative ultrasound (QUS) parameters rem...

    Authors: Min Sun, Mengdie Cao, Qi Fu, Zhenxin Zhu, Chuchen Meng, Jia Mao, Yun Shi, Yu Duan, Wei Tang, Xiaoping Huang, Wei He and Tao Yang

    Citation: BMC Endocrine Disorders 2014 14:14

    Content type: Research article

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  44. Diabetic cardiomyopathy is associated with a number of functional and structural pathological changes such as left ventricular dysfunction, cardiac remodeling, and apoptosis. The primary cause of diabetic card...

    Authors: Romana Bohuslavova, Frantisek Kolar, David Sedmera, Lada Skvorova, Frantisek Papousek, Jan Neckar and Gabriela Pavlinkova

    Citation: BMC Endocrine Disorders 2014 14:11

    Content type: Research article

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  45. Adipose tissue (AT) contributes to metabolic dysfunction through imbalanced production of adipokines, including cytokines. Visceral AT in particular is associated with metabolic disorders, indicating a specifi...

    Authors: Henrik Svensson, Birgitta Odén, Staffan Edén and Malin Lönn

    Citation: BMC Endocrine Disorders 2014 14:7

    Content type: Research article

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  46. Several studies have shown the association of solute carrier family 30 (zinc transporter) member 8 (SLC30A8) rs13266634 with type 2 diabetes (T2D). However, the association of alternative variants and haplotyp...

    Authors: Sameer D Salem, Riyadh Saif-Ali, Ikram S Ismail, Zaid Al-Hamodi and Sekaran Muniandy

    Citation: BMC Endocrine Disorders 2014 14:2

    Content type: Research article

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  47. One possible barrier to effective diabetes self-management is hypoglycaemia associated with diabetes medication. The current study was conducted to characterize hypoglycaemic events among UK patients with type...

    Authors: Beth D Mitchell, Jeffrey Vietri, Anthony Zagar, Bradley Curtis and Matthew Reaney

    Citation: BMC Endocrine Disorders 2013 13:59

    Content type: Research article

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