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Diabetes and Metabolism

Section edited by Abd Tahrani

This section concerns all aspects of diabetes and metabolic syndrome including but not limited to: prevention, diagnosis and management, as well as related molecular genetics, and pathophysiology.

Page 4 of 6

  1. Acarbose slows down the intestinal absorption of carbohydrates, but its effects on the secretion of incretins are still poorly known. This study aimed to examine the effects of single-dose acarbose on the secr...

    Authors: Zhong Chen, Xiaoying Fu, Jian Kuang, Ju Chen, Hongmei Chen, Jianhao Pei and Huazhang Yang

    Citation: BMC Endocrine Disorders 2016 16:55

    Content type: Research article

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  2. To evaluate the neonatal and obstetric outcomes of pregnancies complicated by gestational diabetes mellitus (GDM). Screening and treatment – diet-only versus additional insulin therapy – were based on the 2010...

    Authors: Sarah H. Koning, Klaas Hoogenberg, Kirsten A. Scheuneman, Mick G. Baas, Fleurisca J. Korteweg, Krystyna M. Sollie, Bertine J. Schering, Aren J. van Loon, Bruce H.R. Wolffenbuttel, Paul P. van den Berg and Helen L. Lutgers

    Citation: BMC Endocrine Disorders 2016 16:52

    Content type: Research article

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  3. Current international guidelines advocate achieving at least a 30 % reduction in maximum plantar pressure to reduce the risk of foot ulcers in people with diabetes. However, whether plantar pressures differ in...

    Authors: Malindu E. Fernando, Robert G. Crowther, Peter A. Lazzarini, Kunwarjit S. Sangla, Scott Wearing, Petra Buttner and Jonathan Golledge

    Citation: BMC Endocrine Disorders 2016 16:51

    Content type: Research article

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  4. Early identification of children and adolescents with type 1 diabetes at high risk for development of complications is important, as early intervention may prevent further deterioration. Here we investigate th...

    Authors: Josine C. van der Heyden, Erwin Birnie, Dick Mul, Sarah Bovenberg, Henk J. Veeze and Henk-Jan Aanstoot

    Citation: BMC Endocrine Disorders 2016 16:49

    Content type: Research article

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  5. Evidence on the role of irisin in insulin resistance is limited and controversial, and pathways between them remain unknown. We aimed to examine the independent effects of circulating irisin and different adip...

    Authors: Xiulin Shi, Mingzhu Lin, Changqin Liu, Fangsen Xiao, Yongwen Liu, Peiying Huang, Xin Zeng, Bing Yan, Suhuan Liu, Xiaoying Li, Shuyu Yang, Xuejun Li and Zhibin Li

    Citation: BMC Endocrine Disorders 2016 16:44

    Content type: Research article

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  6. Screening for undiagnosed diabetes is not widely undertaken due to the high costs and invasiveness of blood sampling. Simple non-invasive tools to identify high risk individuals can facilitate screening. The m...

    Authors: P. Katulanda, N. R. Hill, I. Stratton, R. Sheriff, S. D. N. De Silva and D. R. Matthews

    Citation: BMC Endocrine Disorders 2016 16:42

    Content type: Research article

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  7. Patients with type 2 diabetes mellitus (T2DM) who participate in diabetes management programs have been shown to have better glycemic control and slower disease progression, although program participation rema...

    Authors: Janice M. S. Lopez, Bozena J. Katic, Marcy Fitz-Randolph, Richard A. Jackson, Wing Chow and C. Daniel Mullins

    Citation: BMC Endocrine Disorders 2016 16:41

    Content type: Research article

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  8. It is essential to anticipate and limit the social, economic and sanitary cost of type 2 diabetes (T2D), which is in constant progression worldwide.

    Authors: Sylvie Erpeldinger, Michaela B. Rehman, Christophe Berkhout, Christophe Pigache, Yves Zerbib, Francis Regnault, Emilie Guérin, Irène Supper, Catherine Cornu, Behrouz Kassaï, François Gueyffier and Rémy Boussageon

    Citation: BMC Endocrine Disorders 2016 16:39

    Content type: Research article

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  9. Diabetic foot ulceration is receiving more attention because of its high amputation and mortality rate. It is essential to establish the frequency of amputations in people with diabetes after any change to the...

    Authors: Chuan Wang, Lifang Mai, Chuan Yang, Dan Liu, Kan Sun, Weidong Song, Baoming Luo, Yan Li, Mingtong Xu, Shaoling Zhang, Fangping Li, Meng Ren and Li Yan

    Citation: BMC Endocrine Disorders 2016 16:38

    Content type: Research article

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  10. The aim of this study was to compare the efficacy, safety, costs, and cost-effectiveness of biphasic insulin aspart 30 (BIAsp 30) with NPH plus regular human insulin (NPH/Reg) in patients with type 2 diabetes ...

    Authors: Amir Farshchi, Rokhsareh Aghili, Maryam Oskuee, Marjan Rashed, Sina Noshad, Abbas Kebriaeezadeh, Maryam Kia and Alireza Esteghamati

    Citation: BMC Endocrine Disorders 2016 16:35

    Content type: Research article

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  11. Oxytocin (OT) emerges as a drug for the treatment of diabetes and obesity. The entire OT system is synthesized in the rat and human heart. The direct myocardial infusion with OT into an ischemic or failing hea...

    Authors: Marek Jankowski, Tom L. Broderick and Jolanta Gutkowska

    Citation: BMC Endocrine Disorders 2016 16:34

    Content type: Review

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  12. Pancreatic β-cell dysfunction resulting from inflammation has been recognized to contribute to type 2 diabetes mellitus (T2DM). Netrin-1 is a new indicator of subclinical inflammation and it has a role in β-ce...

    Authors: Chenxiao Liu, Xianjin Ke, Ying Wang, Xiu Feng, Qi Li, Ying Zhang, Jian Zhu and Qian Li

    Citation: BMC Endocrine Disorders 2016 16:33

    Content type: Research article

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  13. To describe common type 2 diabetes treatment intensification regimens, patients’ characteristics and changes in glycated hemoglobin (HbA1c) and body mass index (BMI).

    Authors: Christianne L. Roumie, Robert A. Greevy, Carlos G. Grijalva, Adriana M. Hung, Xulei Liu and Marie R. Griffin

    Citation: BMC Endocrine Disorders 2016 16:32

    Content type: Research article

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  14. Patients with myocardial infarction (MI) have a high mortality. Therefore, new risk markers and predictors of an adverse outcome for MI are required. The role of hyperglycemia in the development of cardiovascu...

    Authors: Victoria Karetnikova, Olga Gruzdeva, Evgenya Uchasova, Anastasia Osokina and Olga Barbarash

    Citation: BMC Endocrine Disorders 2016 16:31

    Content type: Research article

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  15. Advance in medicine has led to an increase in life expectancy of elderly diabetic patients especially on the growing population called the “oldest old”, those in their mid-80s upwards. The aim of this study is...

    Authors: Thewjitcharoen Yotsapon, Krittiyawong Sirinate, Wanothayaroj Ekgaluck, Vongterapak Somboon, Anuntakulnatee Tawee, Kittipoom Worawit, Nakasatien Soontaree and Himathongkam Thep

    Citation: BMC Endocrine Disorders 2016 16:30

    Content type: Research article

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  16. Type 1 Diabetes Mellitus is a rapidly growing problem in Tanzania. Children and adolescents with type 1 diabetes have previously been found to have poor glycaemic control and high prevalence of complications. ...

    Authors: Mariam Noorani, Kaushik Ramaiya and Karim Manji

    Citation: BMC Endocrine Disorders 2016 16:29

    Content type: Research article

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  17. Effective prevention of type 2 diabetes (T2D) requires early identification of high-risk individuals who might benefit from intervention. We sought to determine whether low serum testosterone, a novel risk fac...

    Authors: Evan Atlantis, Paul Fahey, Sean Martin, Peter O’Loughlin, Anne W. Taylor, Robert J. Adams, Zumin Shi and Gary Wittert

    Citation: BMC Endocrine Disorders 2016 16:26

    Content type: Research article

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  18. Diabetic retinopathy (DRP) is a common microvascular complication seen in patients with type 1 diabetes mellitus (T1DM). The effects of T1DM and concomitant (proliferative) DRP on retinal blood flow are curren...

    Authors: Hoang-Ton Nguyen, Eelco van Duinkerken, Frank D. Verbraak, Bettine C. P. Polak, Peter J. Ringens, Michaela Diamant and Annette C. Moll

    Citation: BMC Endocrine Disorders 2016 16:25

    Content type: Research article

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  19. Safe and effective insulin therapy for diabetes mellitus requires initial dose titration and regular adjustments based on blood glucose (BG) monitoring. Our objective was to explore the use of BG measurement i...

    Authors: Kaisa Miikkulainen, Antonio Caruso, Oliver Mast, Rongrong Zhang and Oleg Borisenko

    Citation: BMC Endocrine Disorders 2016 16:21

    Content type: Research article

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  20. Type B insulin resistance is a rare autoimmune disease characterized by the presence of autoantibodies against the insulin receptor. Helicobacter pylori (H pylori) infection may play a causative role in the au...

    Authors: Guo-Qing Yang, Yi-Jun Li, Jing-Tao Dou, Bao-An Wang, Ju-Ming Lu and Yi-Ming Mu

    Citation: BMC Endocrine Disorders 2016 16:20

    Content type: Case report

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  21. The number and activity of circulating endothelial progenitor cells (EPCs) in prehypertension is preserved in premenopausal women. However, whether this favorable effect still exists in prehypertensive premeno...

    Authors: Haitao Zeng, Yanping Jiang, Hailin Tang, Zi Ren, Gaofeng Zeng and Zhen Yang

    Citation: BMC Endocrine Disorders 2016 16:13

    Content type: Research article

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  22. Information about the achievement of glycemic targets in patients with type 2 diabetes according to different individualization strategies is scarce. Our aim was to analyze the allocation of type 2 diabetic pa...

    Authors: I. Miñambres, J. J. Mediavilla, J. Sarroca and A. Pérez

    Citation: BMC Endocrine Disorders 2016 16:10

    Content type: Research article

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  23. The metabolic impact of participating in a diabetes camp is little known among children and adolescents living with type 1 diabetes in sub-Saharan Africa. We aimed to assess the changes in glycemic control and...

    Authors: Mesmin Y. Dehayem, Rémy Takogue, Siméon-Pierre Choukem, Olivier T. S. Donfack, Jean-Claude Katte, Suzanne Sap, Eugène Sobngwi and Jean-Claude Mbanya

    Citation: BMC Endocrine Disorders 2016 16:5

    Content type: Research article

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  24. Hospital inpatient care for patients with diabetes was estimated to cost $76 billion in 2012. Substantial expense resulted from those patients having multiple hospitalizations. The objective was to compare the...

    Authors: Pamela C. Heaton, Vibha C. A. Desai, Christina M. L. Kelton and Swapnil N. Rajpathak

    Citation: BMC Endocrine Disorders 2016 16:4

    Content type: Research article

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  25. Type 2 diabetic patients display significantly higher incidence of cardiovascular (CV) events including stroke compared to non-diabetics. Morning blood pressure surge (MBPS) and blunted systolic night-day (SND...

    Authors: Johanne M. Lyhne, Esben Laugesen, Pernille Høyem, Simon Cichosz, Jens S. Christiansen, Søren T. Knudsen, Klavs W. Hansen, Troels K. Hansen and Per L. Poulsen

    Citation: BMC Endocrine Disorders 2015 15:77

    Content type: Research article

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  26. High osteoprotegerin (OPG) has been reported in association with insulin resistance and type 2 diabetes. We aimed to evaluate the association of serum OPG with impaired glucose regulation (IGR) and microalbumi...

    Authors: Yixin Niu, Zhen Yang, Xiaoyong Li, Weiwei Zhang, Shuai Lu, Hongmei Zhang, Xueru Chen, Lingfei Zhu, Yin Xing, Guang Ning, Li Qin and Qing Su

    Citation: BMC Endocrine Disorders 2015 15:75

    Content type: Research article

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  27. Alterations in intestinal microbiota correlate with risk of development of obesity and type 2 diabetes. Probiotics have been suggested to play an important role in the management of dysglycemia, although the e...

    Authors: Qun Yan, Xu Li and Bo Feng

    Citation: BMC Endocrine Disorders 2015 15:74

    Content type: Study protocol

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  28. Canagliflozin, an oral agent that inhibits sodium glucose co-transporter 2, improves glycemic control, body weight, and blood pressure and is generally well tolerated in patients with type 2 diabetes mellitus ...

    Authors: Erin K. Buysman, Wing Chow, Henry J. Henk and Marcia F. T. Rupnow

    Citation: BMC Endocrine Disorders 2015 15:67

    Content type: Research article

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  29. Foot ulceration is the main precursor to lower limb amputation in patients with type 2 diabetes worldwide. Biomechanical factors have been implicated in the development of foot ulceration; however the associat...

    Authors: Malindu Eranga Fernando, Robert George Crowther, Margaret Cunningham, Peter Anthony Lazzarini, Kunwarjit Singh Sangla and Jonathan Golledge

    Citation: BMC Endocrine Disorders 2015 15:59

    Content type: Study protocol

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  30. Diabetes mellitus (DM) leads to multiple complications, including severe hypoglycaemia events (SHEs). SHEs can impact a patient’s quality of life and compliance and may directly result in additional costs to t...

    Authors: Marcin Czech, Elżbieta Rdzanek, Justyna Pawęska, Olga Adamowicz-Sidor, Maciej Niewada and Michał Jakubczyk

    Citation: BMC Endocrine Disorders 2015 15:57

    Content type: Research article

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  31. Patients with type-2 diabetes mellitus (T2DM) and hypertension have increased risk of cardiovascular disease (CVD). We studied individualized treatment targets and their achievement in clinical practice.

    Authors: Roland E Schmieder, Anselm K Gitt, Cornelia Koch, Peter Bramlage, Taoufik Ouarrak and Diethelm Tschöpe

    Citation: BMC Endocrine Disorders 2015 15:23

    Content type: Research article

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  32. Continuous glucose monitoring (CGM) has revolutionised diabetes management. CGM enables complete visualisation of the glucose profile, and the uncovering of metabolic ‘weak points’. A standardised procedure to...

    Authors: Petra Augstein, Peter Heinke, Lutz Vogt, Roberto Vogt, Christine Rackow, Klaus-Dieter Kohnert and Eckhard Salzsieder

    Citation: BMC Endocrine Disorders 2015 15:22

    Content type: Research article

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  33. To explore clinical characteristics and beta cell function in Chinese patients with newly diagnosed drug naive type 2 diabetes mellitus (T2DM) with different levels of serum triglyceride (TG).

    Authors: Shuang Zheng, Huan Zhou, Tingting Han, Yangxue Li, Yao Zhang, Wei Liu and Yaomin Hu

    Citation: BMC Endocrine Disorders 2015 15:21

    Content type: Research article

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  34. Psychosocial problems are common in patients with diabetes. However, data on psychosocial issues affecting patients with diabetes in Zambia are scarce. The present study explored sources of stress, stress copi...

    Authors: Given Hapunda, Amina Abubakar, Fons van de Vijver and Frans Pouwer

    Citation: BMC Endocrine Disorders 2015 15:20

    Content type: Research article

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  35. The hormone somatostatin inhibits growth hormone release from the pituitary gland and is theoretically linked to diabetes and diabetes related complications. This study aimed to investigate the relationship be...

    Authors: Peter R van Dijk, Gijs WD Landman, Larissa van Essen, Joachim Struck, Klaas H Groenier, Henk JG Bilo, Stephan JL Bakker and Nanne Kleefstra

    Citation: BMC Endocrine Disorders 2015 15:19

    Content type: Research article

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  36. Primary care physicians (PCPs) are the main providers of diabetes care especially in resource-limited countries which experience extreme shortage of specialists. The present study aimed to evaluate PCPs’ appro...

    Authors: Ahmadou M Jingi, Jobert Richie N Nansseu and Jean Jacques N Noubiap

    Citation: BMC Endocrine Disorders 2015 15:18

    Content type: Research article

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  37. Platelet hyperreactivity is a factor which contributes towards increased risk of cardiovascular events in adults with type 2 diabetes (T2DM). However, little is known about platelets’ disturbances among childr...

    Authors: Beata Malachowska, Bartlomiej Tomasik, Agnieszka Szadkowska, Anna Baranowska-Jazwiecka, Olga Wegner, Wojciech Mlynarski and Wojciech Fendler

    Citation: BMC Endocrine Disorders 2015 15:17

    Content type: Research article

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  38. The concept is now emerging that higher thyroid-stimulating hormone (TSH) and lower thyroid hormone levels within the euthyroid range may adversely affect atherosclerosis. The aim of this study was to investig...

    Authors: Yun Zhang, Ping Lu, Ling Zhang and Xinhua Xiao

    Citation: BMC Endocrine Disorders 2015 15:12

    Content type: Research article

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  39. Insulin resistance triggered by excess fat is a key pathogenic factor that promotes type 2 diabetes. Understanding molecular mechanisms of insulin resistance may lead to the identification of a novel therapeut...

    Authors: Andreas AK Tandelilin, Tetsuaki Hirase, Athanasius W Hudoyo, Jidong Cheng, Keiko Toyama, Hiroko Morisaki and Takayuki Morisaki

    Citation: BMC Endocrine Disorders 2015 15:11

    Content type: Research article

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    The Erratum to this article has been published in BMC Endocrine Disorders 2015 15:80

  40. Insulin resistance (IR) plays a vital role in the pathogenesis of Type 2 Diabetes Mellitus (T2DM). The mechanism of IR may be associated with inflammation, whereas the neutrophil-lymphocyte ratio (NLR) is a ne...

    Authors: Meiqin Lou, Peng Luo, Ru Tang, Yixian Peng, Siyuan Yu, Wanjing Huang and Lei He

    Citation: BMC Endocrine Disorders 2015 15:9

    Content type: Research article

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  41. Diabetic retinopathy (DR) is an important microvascular complication of diabetes with a high concordance rate in patients with diabetes. Inflammation is supposed to participate in the development of DR. This s...

    Authors: Danfeng Peng, Jie Wang, Rong Zhang, Shanshan Tang, Feng Jiang, Miao Chen, Jing Yan, Xue Sun, Tao Wang, Shiyun Wang, Yuqian Bao, Cheng Hu and Weiping Jia

    Citation: BMC Endocrine Disorders 2015 15:8

    Content type: Research article

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  42. Evidence suggests that activation of κ-opioid receptor (KOR) by U50,488H exhibits potential cardiovascular protective properties. However, the effects of U50,488H on vascular dysfunction in diabetes mellitus (...

    Authors: Xuan Zhou, Dongjuan Wang, Yuyang Zhang, Jinxia Zhang, Dingcheng Xiang and Haichang Wang

    Citation: BMC Endocrine Disorders 2015 15:7

    Content type: Research article

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  43. Vitamin D deficiency reportedly is associated with type 2 diabetes (T2DM). We aim to examine whether 25-hydroxyvitamin D (25OHD) has clinically significant influence on hemoglobin glycation (HbA1c) and insulin...

    Authors: Jayesh J Sheth, Ankna Shah, Frenny J Sheth, Sunil Trivedi, Mamta Lele, Navneet Shah, Premal Thakor and Rama Vaidya

    Citation: BMC Endocrine Disorders 2015 15:5

    Content type: Research article

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  44. In the treatment of childhood type 1 diabetes, being aware of the parents’ fear of hypoglycemia is important, since the parents’ fear may influence the management of treatment and the children’s blood glucose ...

    Authors: Anne Haugstvedt, Tore Wentzel-Larsen, Morten Aarflot, Berit Rokne and Marit Graue

    Citation: BMC Endocrine Disorders 2015 15:2

    Content type: Research article

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  45. The study of endogenous insulin secretion may provide relevant insight into the comparison of the natural history of adult onset latent autoimmune diabetes (LADA) with types 1 and 2 diabetes mellitus. The aim ...

    Authors: Marta Hernandez, Angels Mollo, Josep Ramon Marsal, Aureli Esquerda, Ismael Capel, Manel Puig-Domingo, Paolo Pozzilli, Alberto de Leiva and Didac Mauricio

    Citation: BMC Endocrine Disorders 2015 15:1

    Content type: Research article

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  46. Insulin resistance is one of the hallmark manifestations of obesity and Type II diabetes and reversal of this pathogenic abnormality is an attractive target for new therapies for Type II diabetes. A recent rep...

    Authors: Jidong Cheng, Hiroko Morisaki, Keiko Toyama, Naomi Sugimoto, Takuya Shintani, Andreas Tandelilin, Tetsuaki Hirase, Edward W Holmes and Takayuki Morisaki

    Citation: BMC Endocrine Disorders 2014 14:96

    Content type: Research article

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  47. The combined effect of the metabolic syndrome (MS) risk factors on bone health has led to controversial results and it is still not clear whether this effect is protective or detrimental. The study aimed to ex...

    Authors: Abdellah El Maghraoui, Asmaa Rezqi, Salwa El Mrahi, Siham Sadni, Imad Ghozlani and Aziza Mounach

    Citation: BMC Endocrine Disorders 2014 14:93

    Content type: Research article

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  48. In primary health care systems where member’s turnover is relatively low, the question, whether investment in quality of care improvement can make a business case, or is cost effective, has not been fully answ...

    Authors: Rachel Wilf-Miron, Arkadi Bolotin, Nesia Gordon, Avi Porath and Ronit Peled

    Citation: BMC Endocrine Disorders 2014 14:92

    Content type: Research article

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