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Diabetes and Metabolism

Section edited by Abd Tahrani

This section concerns all aspects of diabetes and metabolic syndrome including but not limited to: prevention, diagnosis and management, as well as related molecular genetics, and pathophysiology.

Page 4 of 5

  1. Content type: Research article

    The metabolic impact of participating in a diabetes camp is little known among children and adolescents living with type 1 diabetes in sub-Saharan Africa. We aimed to assess the changes in glycemic control and...

    Authors: Mesmin Y. Dehayem, Rémy Takogue, Siméon-Pierre Choukem, Olivier T. S. Donfack, Jean-Claude Katte, Suzanne Sap, Eugène Sobngwi and Jean-Claude Mbanya

    Citation: BMC Endocrine Disorders 2016 16:5

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  2. Content type: Research article

    Hospital inpatient care for patients with diabetes was estimated to cost $76 billion in 2012. Substantial expense resulted from those patients having multiple hospitalizations. The objective was to compare the...

    Authors: Pamela C. Heaton, Vibha C. A. Desai, Christina M. L. Kelton and Swapnil N. Rajpathak

    Citation: BMC Endocrine Disorders 2016 16:4

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  3. Content type: Research article

    Type 2 diabetic patients display significantly higher incidence of cardiovascular (CV) events including stroke compared to non-diabetics. Morning blood pressure surge (MBPS) and blunted systolic night-day (SND...

    Authors: Johanne M. Lyhne, Esben Laugesen, Pernille Høyem, Simon Cichosz, Jens S. Christiansen, Søren T. Knudsen, Klavs W. Hansen, Troels K. Hansen and Per L. Poulsen

    Citation: BMC Endocrine Disorders 2015 15:77

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  4. Content type: Research article

    High osteoprotegerin (OPG) has been reported in association with insulin resistance and type 2 diabetes. We aimed to evaluate the association of serum OPG with impaired glucose regulation (IGR) and microalbumi...

    Authors: Yixin Niu, Zhen Yang, Xiaoyong Li, Weiwei Zhang, Shuai Lu, Hongmei Zhang, Xueru Chen, Lingfei Zhu, Yin Xing, Guang Ning, Li Qin and Qing Su

    Citation: BMC Endocrine Disorders 2015 15:75

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  5. Content type: Study protocol

    Alterations in intestinal microbiota correlate with risk of development of obesity and type 2 diabetes. Probiotics have been suggested to play an important role in the management of dysglycemia, although the e...

    Authors: Qun Yan, Xu Li and Bo Feng

    Citation: BMC Endocrine Disorders 2015 15:74

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  6. Content type: Research article

    Canagliflozin, an oral agent that inhibits sodium glucose co-transporter 2, improves glycemic control, body weight, and blood pressure and is generally well tolerated in patients with type 2 diabetes mellitus ...

    Authors: Erin K. Buysman, Wing Chow, Henry J. Henk and Marcia F. T. Rupnow

    Citation: BMC Endocrine Disorders 2015 15:67

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  7. Content type: Study protocol

    Foot ulceration is the main precursor to lower limb amputation in patients with type 2 diabetes worldwide. Biomechanical factors have been implicated in the development of foot ulceration; however the associat...

    Authors: Malindu Eranga Fernando, Robert George Crowther, Margaret Cunningham, Peter Anthony Lazzarini, Kunwarjit Singh Sangla and Jonathan Golledge

    Citation: BMC Endocrine Disorders 2015 15:59

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  8. Content type: Research article

    Diabetes mellitus (DM) leads to multiple complications, including severe hypoglycaemia events (SHEs). SHEs can impact a patient’s quality of life and compliance and may directly result in additional costs to t...

    Authors: Marcin Czech, Elżbieta Rdzanek, Justyna Pawęska, Olga Adamowicz-Sidor, Maciej Niewada and Michał Jakubczyk

    Citation: BMC Endocrine Disorders 2015 15:57

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  9. Content type: Research article

    Patients with type-2 diabetes mellitus (T2DM) and hypertension have increased risk of cardiovascular disease (CVD). We studied individualized treatment targets and their achievement in clinical practice.

    Authors: Roland E Schmieder, Anselm K Gitt, Cornelia Koch, Peter Bramlage, Taoufik Ouarrak and Diethelm Tschöpe

    Citation: BMC Endocrine Disorders 2015 15:23

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  10. Content type: Research article

    Continuous glucose monitoring (CGM) has revolutionised diabetes management. CGM enables complete visualisation of the glucose profile, and the uncovering of metabolic ‘weak points’. A standardised procedure to...

    Authors: Petra Augstein, Peter Heinke, Lutz Vogt, Roberto Vogt, Christine Rackow, Klaus-Dieter Kohnert and Eckhard Salzsieder

    Citation: BMC Endocrine Disorders 2015 15:22

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  11. Content type: Research article

    To explore clinical characteristics and beta cell function in Chinese patients with newly diagnosed drug naive type 2 diabetes mellitus (T2DM) with different levels of serum triglyceride (TG).

    Authors: Shuang Zheng, Huan Zhou, Tingting Han, Yangxue Li, Yao Zhang, Wei Liu and Yaomin Hu

    Citation: BMC Endocrine Disorders 2015 15:21

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  12. Content type: Research article

    Psychosocial problems are common in patients with diabetes. However, data on psychosocial issues affecting patients with diabetes in Zambia are scarce. The present study explored sources of stress, stress copi...

    Authors: Given Hapunda, Amina Abubakar, Fons van de Vijver and Frans Pouwer

    Citation: BMC Endocrine Disorders 2015 15:20

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  13. Content type: Research article

    The hormone somatostatin inhibits growth hormone release from the pituitary gland and is theoretically linked to diabetes and diabetes related complications. This study aimed to investigate the relationship be...

    Authors: Peter R van Dijk, Gijs WD Landman, Larissa van Essen, Joachim Struck, Klaas H Groenier, Henk JG Bilo, Stephan JL Bakker and Nanne Kleefstra

    Citation: BMC Endocrine Disorders 2015 15:19

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  14. Content type: Research article

    Primary care physicians (PCPs) are the main providers of diabetes care especially in resource-limited countries which experience extreme shortage of specialists. The present study aimed to evaluate PCPs’ appro...

    Authors: Ahmadou M Jingi, Jobert Richie N Nansseu and Jean Jacques N Noubiap

    Citation: BMC Endocrine Disorders 2015 15:18

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  15. Content type: Research article

    Platelet hyperreactivity is a factor which contributes towards increased risk of cardiovascular events in adults with type 2 diabetes (T2DM). However, little is known about platelets’ disturbances among childr...

    Authors: Beata Malachowska, Bartlomiej Tomasik, Agnieszka Szadkowska, Anna Baranowska-Jazwiecka, Olga Wegner, Wojciech Mlynarski and Wojciech Fendler

    Citation: BMC Endocrine Disorders 2015 15:17

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  16. Content type: Research article

    The concept is now emerging that higher thyroid-stimulating hormone (TSH) and lower thyroid hormone levels within the euthyroid range may adversely affect atherosclerosis. The aim of this study was to investig...

    Authors: Yun Zhang, Ping Lu, Ling Zhang and Xinhua Xiao

    Citation: BMC Endocrine Disorders 2015 15:12

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  17. Content type: Research article

    Insulin resistance triggered by excess fat is a key pathogenic factor that promotes type 2 diabetes. Understanding molecular mechanisms of insulin resistance may lead to the identification of a novel therapeut...

    Authors: Andreas AK Tandelilin, Tetsuaki Hirase, Athanasius W Hudoyo, Jidong Cheng, Keiko Toyama, Hiroko Morisaki and Takayuki Morisaki

    Citation: BMC Endocrine Disorders 2015 15:11

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    The Erratum to this article has been published in BMC Endocrine Disorders 2015 15:80

  18. Content type: Research article

    Insulin resistance (IR) plays a vital role in the pathogenesis of Type 2 Diabetes Mellitus (T2DM). The mechanism of IR may be associated with inflammation, whereas the neutrophil-lymphocyte ratio (NLR) is a ne...

    Authors: Meiqin Lou, Peng Luo, Ru Tang, Yixian Peng, Siyuan Yu, Wanjing Huang and Lei He

    Citation: BMC Endocrine Disorders 2015 15:9

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  19. Content type: Research article

    Diabetic retinopathy (DR) is an important microvascular complication of diabetes with a high concordance rate in patients with diabetes. Inflammation is supposed to participate in the development of DR. This s...

    Authors: Danfeng Peng, Jie Wang, Rong Zhang, Shanshan Tang, Feng Jiang, Miao Chen, Jing Yan, Xue Sun, Tao Wang, Shiyun Wang, Yuqian Bao, Cheng Hu and Weiping Jia

    Citation: BMC Endocrine Disorders 2015 15:8

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  20. Content type: Research article

    Evidence suggests that activation of κ-opioid receptor (KOR) by U50,488H exhibits potential cardiovascular protective properties. However, the effects of U50,488H on vascular dysfunction in diabetes mellitus (...

    Authors: Xuan Zhou, Dongjuan Wang, Yuyang Zhang, Jinxia Zhang, Dingcheng Xiang and Haichang Wang

    Citation: BMC Endocrine Disorders 2015 15:7

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  21. Content type: Research article

    Vitamin D deficiency reportedly is associated with type 2 diabetes (T2DM). We aim to examine whether 25-hydroxyvitamin D (25OHD) has clinically significant influence on hemoglobin glycation (HbA1c) and insulin...

    Authors: Jayesh J Sheth, Ankna Shah, Frenny J Sheth, Sunil Trivedi, Mamta Lele, Navneet Shah, Premal Thakor and Rama Vaidya

    Citation: BMC Endocrine Disorders 2015 15:5

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  22. Content type: Research article

    In the treatment of childhood type 1 diabetes, being aware of the parents’ fear of hypoglycemia is important, since the parents’ fear may influence the management of treatment and the children’s blood glucose ...

    Authors: Anne Haugstvedt, Tore Wentzel-Larsen, Morten Aarflot, Berit Rokne and Marit Graue

    Citation: BMC Endocrine Disorders 2015 15:2

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  23. Content type: Research article

    The study of endogenous insulin secretion may provide relevant insight into the comparison of the natural history of adult onset latent autoimmune diabetes (LADA) with types 1 and 2 diabetes mellitus. The aim ...

    Authors: Marta Hernandez, Angels Mollo, Josep Ramon Marsal, Aureli Esquerda, Ismael Capel, Manel Puig-Domingo, Paolo Pozzilli, Alberto de Leiva and Didac Mauricio

    Citation: BMC Endocrine Disorders 2015 15:1

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  24. Content type: Research article

    Insulin resistance is one of the hallmark manifestations of obesity and Type II diabetes and reversal of this pathogenic abnormality is an attractive target for new therapies for Type II diabetes. A recent rep...

    Authors: Jidong Cheng, Hiroko Morisaki, Keiko Toyama, Naomi Sugimoto, Takuya Shintani, Andreas Tandelilin, Tetsuaki Hirase, Edward W Holmes and Takayuki Morisaki

    Citation: BMC Endocrine Disorders 2014 14:96

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  25. Content type: Research article

    The combined effect of the metabolic syndrome (MS) risk factors on bone health has led to controversial results and it is still not clear whether this effect is protective or detrimental. The study aimed to ex...

    Authors: Abdellah El Maghraoui, Asmaa Rezqi, Salwa El Mrahi, Siham Sadni, Imad Ghozlani and Aziza Mounach

    Citation: BMC Endocrine Disorders 2014 14:93

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  26. Content type: Research article

    In primary health care systems where member’s turnover is relatively low, the question, whether investment in quality of care improvement can make a business case, or is cost effective, has not been fully answ...

    Authors: Rachel Wilf-Miron, Arkadi Bolotin, Nesia Gordon, Avi Porath and Ronit Peled

    Citation: BMC Endocrine Disorders 2014 14:92

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  27. Content type: Research article

    Alterations in postprandial metabolism have been described in familial combined hyperlipidemia (FCH); however, their underlying mechanisms are not well characterized. We aimed to identify factors related to th...

    Authors: Paloma Almeda-Valdes, Daniel Cuevas-Ramos, Roopa Mehta, Liliana Muñoz-Hernandez, Ivette Cruz-Bautista, Oscar Perez-Mendez, Maria Teresa Tusie-Luna, Francisco J Gomez-Perez, Päivi Pajukanta, Niina Matikainen, Marja-Riitta Taskinen and Carlos A Aguilar-Salinas

    Citation: BMC Endocrine Disorders 2014 14:90

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  28. Content type: Research article

    Carpal tunnel syndrome (CTS) is the most common entrapment neuropathy encountered in diabetes. The short-term improvement after carpal tunnel release has previously been demonstrated not to differ between pati...

    Authors: Niels OB Thomsen, Jonas Björk and Ragnhild I Cederlund

    Citation: BMC Endocrine Disorders 2014 14:85

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  29. Content type: Research article

    Diabetes has previously been linked to mental health problems in adolescents, but more recent studies have yielded mixed findings. The aim of the current study was to compare symptoms of mental health problems...

    Authors: Børge Sivertsen, Keith J Petrie, Ane Wilhelmsen-Langeland and Mari Hysing

    Citation: BMC Endocrine Disorders 2014 14:83

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  30. Content type: Research article

    Metabolic syndrome (MetS) is a clustering of metabolic risk factors for cardiovascular diseases and type 2 diabetes. The study aimed to estimate the prevalence of MetS, its components, and their associations a...

    Authors: Tran Quang Binh, Pham Tran Phuong, Bui Thi Nhung and Do Dinh Tung

    Citation: BMC Endocrine Disorders 2014 14:77

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  31. Content type: Research article

    Disturbances of the circadian rhythm of cortisol secretion are associated with depression, coronary calcification, and higher all-cause and cardiovascular mortality.

    Authors: Eva O Melin, Maria Thunander, Mona Landin-Olsson, Magnus Hillman and Hans O Thulesius

    Citation: BMC Endocrine Disorders 2014 14:75

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  32. Content type: Research article

    Although multivitamin products are widely used as dietary supplements to maintain health or as special medical food in certain diseases, the effects of these products were not investigated in diabetes mellitus...

    Authors: Márta Sárközy, Veronika Fekete, Gergő Szűcs, Szilvia Török, Csilla Szűcs, Judit Bárkányi, Zoltán V Varga, Imre Földesi, Csaba Csonka, Csaba Kónya, Tamás Csont and Péter Ferdinandy

    Citation: BMC Endocrine Disorders 2014 14:72

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  33. Content type: Research article

    Multi-morbidity, or the presence of multiple chronic diseases, is a major problem in clinical care and is associated with worse outcomes. Additionally, the presence of mental health conditions, such as depress...

    Authors: Cheryl P Lynch, Mulugeta Gebregziabher, Yumin Zhao, Kelly J Hunt and Leonard E Egede

    Citation: BMC Endocrine Disorders 2014 14:68

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  34. Content type: Research article

    Increasing prevalence of pre-diabetes is an emerging public health problem. Decrease in sweet taste sensitivity which can lead to an increase in sugar intake might be a factor driving them to overt diabetes. T...

    Authors: Sudharshani Wasalathanthri, Priyadarshika Hettiarachchi and Shamini Prathapan

    Citation: BMC Endocrine Disorders 2014 14:67

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  35. Content type: Study protocol

    Suboptimal vitamin D status is highly prevalent in Northern communities, particularly in those patients with chronic diseases such as diabetes and chronic renal disease. Emerging literature suggests that adher...

    Authors: Diana R Mager, Stephanie T Jackson, Michelle R Hoffmann, Kailash Jindal and Peter A Senior

    Citation: BMC Endocrine Disorders 2014 14:66

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  36. Content type: Research article

    We aimed to evaluate the predictive utility of common fasting insulin sensitivity indices, and non-laboratory surrogates [BMI, waist circumference (WC) and waist-to-height ratio (WHtR)] in sub-Saharan Africans...

    Authors: Eugene Sobngwi, Andre-Pascal Kengne, Justin B Echouffo-Tcheugui, Simeon Choukem, Joelle Sobngwi-Tambekou, Eric V Balti, Mark S Pearce, Valentin Siaha, Aissa S Mamdjokam, Valery Effoe, Eric Lontchi-Yimagou, Oliver T Donfack, Barbara Atogho-Tiedeu, Philippe Boudou, Jean-Francois Gautier and Jean-Claude Mbanya

    Citation: BMC Endocrine Disorders 2014 14:65

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  37. Content type: Research article

    The Space GlucoseControl system (SGC) is a nurse-driven, computer-assisted device for glycemic control combining infusion pumps with the enhanced Model Predictive Control algorithm (B. Braun, Melsungen, German...

    Authors: Karin Amrein, Norman Kachel, Heike Fries, Roman Hovorka, Thomas R Pieber, Johannes Plank, Urs Wenger, Barbara Lienhardt and Marco Maggiorini

    Citation: BMC Endocrine Disorders 2014 14:62

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  38. Content type: Research article

    The purpose of this analysis is to evaluate the safety and effectiveness of insulin initiation with once-daily insulin detemir (IDet) or insulin glargine (IGlar) in real-life clinical practice in Turkish patie...

    Authors: Taner Damci, Rifat Emral, Anne Louise Svendsen, Tanzer Balkir and Jiten Vora

    Citation: BMC Endocrine Disorders 2014 14:61

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  39. Content type: Study protocol

    Besides the classical role of vitamin D on calcium and bone homeostasis, vitamin D deficiency has recently been identified as a contributing factor in the onset of insulin resistance in type 2 diabetes mellitu...

    Authors: Yvonne HM Krul-Poel, Hans van Wijland, Frank Stam, Edwin ten Boekel, Paul Lips and Suat Simsek

    Citation: BMC Endocrine Disorders 2014 14:59

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  40. Content type: Research article

    Despite the consistent relationship between serum γ-glutamyltransferase (GGT) and type 2 diabetes (T2D), one unsolved issue is the role of serum GGT in the well-known association between obesity and T2D. This ...

    Authors: Nam Soo Hong, Jeong-Gook Kim, Yu-Mi Lee, Hyun-Woo Kim, Sin Kam, Keon-Yeop Kim, Ki-Su Kim and Duk-Hee Lee

    Citation: BMC Endocrine Disorders 2014 14:57

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  41. Content type: Study protocol

    Advanced glycation endproducts (AGEs) contribute to the development of vascular complications of diabetes and have been recently implicated in the pathogenesis of diabetes. Since AGEs are generated within food...

    Authors: Nicole J Kellow, Melinda T Coughlan, Gayle S Savige and Christopher M Reid

    Citation: BMC Endocrine Disorders 2014 14:55

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  42. Content type: Research article

    Oral medication for patients with type 2 diabetes mellitus plays an important role in diabetes care and is associated with a high level self-care behavior and self-management. However, poor adherence to diabet...

    Authors: Sunya-Lee Antoine, Dawid Pieper, Tim Mathes and Michaela Eikermann

    Citation: BMC Endocrine Disorders 2014 14:53

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  43. Content type: Research article

    Obesity and gestational diabetes (GDM) in pregnancy are recognized risk factors for adverse outcomes, including cesarean section (CS), macrosomia and preeclampsia. The aim of this study was to investigate the ...

    Authors: Hayfaa A Wahabi, Amel A Fayed, Rasmieh A Alzeidan and Ahmed A Mandil

    Citation: BMC Endocrine Disorders 2014 14:47

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  44. Content type: Research article

    11 patients were referred to our Molecular Genetics Department at the Royal Devon and Exeter Hospital between 2000-2012 with a physician’s diagnosis of remitting diabetes. Our aim was to identify patients with...

    Authors: Tarig Babiker, Ali J Chakera, Maggie Shepherd and Andrew T Hattersley

    Citation: BMC Endocrine Disorders 2014 14:45

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  45. Content type: Research article

    Previously considered as a disease of the affluent, west or urban people and not of public health importance, diabetes mellitus is increasingly becoming a significant cause of morbidity and mortality in sub-Sahar...

    Authors: Kelias Phiri Msyamboza, Chimwemwe J Mvula and Damson Kathyola

    Citation: BMC Endocrine Disorders 2014 14:41

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  46. Content type: Research article

    Few studies have examined young adults with type 1 diabetes use of health services and the development of vascular complications. As part of the Youth Outreach for Diabetes (YOuR-Diabetes) project, this study ...

    Authors: Steven James, Lin Perry, Robyn Gallagher, Julia Lowe, Janet Dunbabin, Patrick McElduff, Shamasunder Acharya and Katharine Steinbeck

    Citation: BMC Endocrine Disorders 2014 14:39

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  47. Content type: Research article

    Canagliflozin is a sodium glucose co-transporter 2 inhibitor developed for the treatment of patients with type 2 diabetes mellitus (T2DM). The efficacy and safety of canagliflozin were evaluated in patients wi...

    Authors: Alan Sinclair, Bruce Bode, Stewart Harris, Ujjwala Vijapurkar, Cristiana Mayer, Albert Fung, Wayne Shaw, Keith Usiskin, Mehul Desai and Gary Meininger

    Citation: BMC Endocrine Disorders 2014 14:37

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  48. Content type: Research article

    Insulin aspart (IAsp) and its biphasic preparations BIAsp50 and BIAsp70 (containing 50% and 70% IAsp, respectively) have distinct glucose-lowering properties as compared to human insulin (HI). We investigated ...

    Authors: Zhulin Ma, Jens Sandahl Christiansen, Torben Laursen, Chunsen Wu, Torsten Lauritzen, Tina Parkner and Jan Frystyk

    Citation: BMC Endocrine Disorders 2014 14:35

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