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Diabetes and Metabolism

Section edited by Abd Tahrani

This section concerns all aspects of diabetes and metabolic syndrome including but not limited to: prevention, diagnosis and management, as well as related molecular genetics, and pathophysiology.

Page 1 of 4

  1. Content type: Research article

    Type 1 diabetes mellitus (T1DM) is one of the most common chronic diseases in children. Studies on costs related to T1DM are scarce and focused primarily on the costs directly related to diabetes. We aimed to ...

    Authors: E. A. J. M. Spaans, P. R. van Dijk, K. H. Groenier, P. L. P. Brand, N. Kleefstra and H. J. G. Bilo

    Citation: BMC Endocrine Disorders 2018 18:57

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  2. Content type: Research article

    The shapes of the plasma glucose concentration curve during the oral glucose tolerance test are related to different metabolic risk profiles and future risk of type 2 DM. We sought to further analyze the relat...

    Authors: Leonardo de Andrade Mesquita, Luciana Pavan Antoniolli, Giordano Fabricio Cittolin-Santos and Fernando Gerchman

    Citation: BMC Endocrine Disorders 2018 18:56

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  3. Content type: Research article

    Diabetic foot ulceration is a serious limb-threatening complication of diabetes. It is the common cause of hospital admissions and amputations.

    Authors: Bilal Bin Younis, Adeela Shahid, Rozina Arshad, Saima Khurshid, Muhammad Ahmad and Haroon Yousaf

    Citation: BMC Endocrine Disorders 2018 18:53

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  4. Content type: Research article

    To compare the accuracy of different obesity indexes, including waist circumference (WC), weight-to-height ratio (WHtR), body mass index (BMI), and lipid accumulation product (LAP), in predicting metabolic syn...

    Authors: Leilei Liu, Yu Liu, Xizhuo Sun, Zhaoxia Yin, Honghui Li, Kunpeng Deng, Xu Chen, Cheng Cheng, Xinping Luo, Ming Zhang, Linlin Li, Lu Zhang, Bingyuan Wang, Yongcheng Ren, Yang Zhao, Dechen Liu…

    Citation: BMC Endocrine Disorders 2018 18:54

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  5. Content type: Research article

    Type 2 Diabetes Mellitus is a serious metabolic disease that is often associated with vascular complications. There are 1.9 million people living with Diabetes in Ethiopia; diabetes mellitus is found to be the...

    Authors: Haileab Fekadu Wolde, Asrat Atsedeweyen, Addisu Jember, Tadesse Awoke, Malede Mequanent, Adino Tesfahun Tsegaye and Shitaye Alemu

    Citation: BMC Endocrine Disorders 2018 18:52

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  6. Content type: Research article

    Glycaemic control is one of the most effective strategies for the treatment of diabetes-related erectile dysfunction (DMED). Compared to conventional anti-diabetic drugs and insulin, islet transplantation is m...

    Authors: Zhigang Wu, Hongwei Wang, Fubiao Ni, Xuan Jiang, Ziqiang Xu, Chengyang Liu, Yong Cai, Hongxing Fu, Jiao Luo, Wenwei Chen, Bicheng Chen and Zhixian Yu

    Citation: BMC Endocrine Disorders 2018 18:49

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  7. Content type: Research article

    Diabetes in the United States has reached epidemic proportions and the people of Appalachia have been disproportionately affected by this disease. Strategies that complement standard diabetes care are critical...

    Authors: Elizabeth A. Beverly, Jane Hamel-Lambert, Laura L. Jensen, Sue Meeks and Anne Rubin

    Citation: BMC Endocrine Disorders 2018 18:50

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  8. Content type: Research article

    Optimal glycaemia, reflected by glycated haemoglobin (HbA1c) levels, is key in reducing type 2 diabetes (T2D) complications. However, most people with T2D have suboptimal recall and understanding of HbA1c. Con...

    Authors: Mei Lyn Tan, Jo-Anne Manski-Nankervis, Sharmala Thuraisingam, Alicia Jenkins, David O’Neal and John Furler

    Citation: BMC Endocrine Disorders 2018 18:47

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  9. Content type: Research article

    The benefit results of postoperative tight glycemic control (TGC) were controversial and there was a lack of well-powered studies that support current guideline recommendations.

    Authors: Yuan-yuan Wang, Shuang-fei Hu, Hui-min Ying, Long Chen, Hui-li Li, Fang Tian and Zhen-feng Zhou

    Citation: BMC Endocrine Disorders 2018 18:42

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  10. Content type: Research article

    The prevalence of childhood obesity and obesity-related metabolic disorder such as dyslipidemia has sharply increased in the past few decades. Chronic low-grade inflammation is associated with the development ...

    Authors: Yuesheng Liu, Dong Xu, Chunyan Yin, Sisi Wang, Min Wang and Yanfeng Xiao

    Citation: BMC Endocrine Disorders 2018 18:39

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  11. Content type: Research article

    Hypoglycaemia is a feared experience for people with diabetes. We aimed to study the prevalence and causes of hypoglycaemia among Sri Lankans with diabetes.

    Authors: H. A. Dissanayake, G. S. P. Keerthisena, K. K. K. Gamage, J. H. Liyanage, I. R. H. S. Ihalagama, W. M. U. A. Wijetunga, T. A. D. Tillekaratne, G. W. Katulanda and P. Katulanda

    Citation: BMC Endocrine Disorders 2018 18:35

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  12. Content type: Research article

    Diabetes mellitus is one of the most prevalent diseases worldwide. Diabetes is a chronic disease associated with micro- and macro-vascular complications and deterioration in general health status. Therefore, t...

    Authors: Masoud Behzadifar, Rahim Sohrabi, Roghayeh Mohammadibakhsh, Morteza Salemi, Sharare Taheri Moghadam, Masood Taheri Mirghaedm, Meysam Behzadifar, Hamid Reza Baradaran and Nicola Luigi Bragazzi

    Citation: BMC Endocrine Disorders 2018 18:34

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  13. Content type: Research article

    There is evidence that disparities exist in diabetes prevalence, access to diabetes care, diabetes-related complications, and the quality of diabetes care. A wide range of interventions has been implemented an...

    Authors: Natalie Terens, Simona Vecchi, Anna Maria Bargagli, Nera Agabiti, Zuzana Mitrova, Laura Amato and Marina Davoli

    Citation: BMC Endocrine Disorders 2018 18:31

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  14. Content type: Research article

    Diabetes mellitus is usually preceded by a pre-diabetic stage before the clinical presentation of the disease, the influence of which on persons’ quality of life is not adequately elucidated. The purpose of th...

    Authors: Konstantinos Makrilakis, Stavros Liatis, Afroditi Tsiakou, Chryssoula Stathi, Eleftheria Papachristoforou, Despoina Perrea, Nicholas Katsilambros, Nikolaos Kontodimopoulos and Dimitrios Niakas

    Citation: BMC Endocrine Disorders 2018 18:32

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  15. Content type: Case report

    The diagnosis of atypical non-autoimmune forms of diabetes mellitus, such as maturity onset diabetes of the young (MODY) presents several challenges, in view of the extensive clinical and genetic heterogeneity...

    Authors: Nikolai Paul Pace, Johann Craus, Alex Felice and Josanne Vassallo

    Citation: BMC Endocrine Disorders 2018 18:28

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  16. Content type: Research article

    Retinol binding protein 4 (RBP4), a protein secreted by adipocytes and bound in plasma to transthyretin (TTR), has been associated with obesity, the early phase of insulin resistance, metabolic syndrome, and t...

    Authors: Karunee Kwanbunjan, Pornpimol Panprathip, Chanchira Phosat, Noppanath Chumpathat, Naruemon Wechjakwen, Somchai Puduang, Ratchada Auyyuenyong, Ina Henkel and Florian J. Schweigert

    Citation: BMC Endocrine Disorders 2018 18:26

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  17. Content type: Case report

    Here, we report a case of central pontine demyelinization in a type-2 diabetes patient with hyperglycemia after a binge-eating attack in the absence of a relevant hyponatremia.

    Authors: Rainer U. Pliquett, Arno Noll, Richard Ibe, Alexandra Katz, Charlotte Ackmann, Alexandra Schreiber and Matthias Girndt

    Citation: BMC Endocrine Disorders 2018 18:18

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  18. Content type: Research article

    The evaluation of metabolic syndrome in a society predisposed to the diabetes mellitus epidemic opens a new avenue to understanding this rapidly growing global metabolic problem. Although Saudi Arabia reports ...

    Authors: Khalid Al-Rubeaan, Nahla Bawazeer, Yousuf Al Farsi, Amira M. Youssef, Abdulrahman A. Al-Yahya, Hamid AlQumaidi, Basim M. Al-Malki, Khalid A. Naji, Khalid Al-Shehri and Fahd I. Al Rumaih

    Citation: BMC Endocrine Disorders 2018 18:16

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  19. Content type: Research article

    Impaired insulin activity in women with polycystic ovary syndrome might differ from that seen in type 2 diabetes mellitus without polycystic ovary syndrome. This study was designed to compare the effects of tr...

    Authors: Tao Tao, Peihong Wu, Yuying Wang and Wei Liu

    Citation: BMC Endocrine Disorders 2018 18:14

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  20. Content type: Research article

    Continuous glucose monitoring (CGM) enables users to view real-time interstitial glucose readings and provides information on the direction and rate of change of blood glucose levels. Users can also access his...

    Authors: J. Lawton, M. Blackburn, J. Allen, F. Campbell, D. Elleri, L. Leelarathna, D. Rankin, M. Tauschmann, H. Thabit and R. Hovorka

    Citation: BMC Endocrine Disorders 2018 18:12

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  21. Content type: Research article

    Limited real-world data are currently available on hypoglycemia in diabetes patients. The International Operations Hypoglycemia Assessment Tool (IO HAT) study was designed to estimate hypoglycemia in insulin-t...

    Authors: Rıfat Emral, Tamer Tetiker, Ibrahim Sahin, Ramazan Sari, Ahmet Kaya, İlhan Yetkin, Sefika Uslu Cil and Neslihan Başcıl Tütüncü

    Citation: BMC Endocrine Disorders 2018 18:9

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  22. Content type: Research article

    Increased knowledge concerning the differences in the illness perception and self-management among sexes is needed for planning proper support programs for patients with diabetes. The aim of this study was to ...

    Authors: Wimonrut Boonsatean, Anna Carlsson, Irena Dychawy Rosner and Margareta Östman

    Citation: BMC Endocrine Disorders 2018 18:5

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  23. Content type: Research article

    This retrospective study investigated the effect of adding metformin to pharmacologic insulin dosing in type 1 diabetics on insulin therapy 1 year after treatment compared with patients on insulin therapy alone.

    Authors: Selvihan Beysel, Ilknur Ozturk Unsal, Muhammed Kizilgul, Mustafa Caliskan, Bekir Ucan and Erman Cakal

    Citation: BMC Endocrine Disorders 2018 18:1

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  24. Content type: Research article

    Diabetes is one of the most common metabolic disorders, with a high prevalence of patients with poor metabolic control. Worldwide, evidence highlights the importance of developing and implementing educational ...

    Authors: Maria do Rosário Pinto, Pedro Miguel Dinis Santos Parreira, Marta Lima Basto and Lisete dos Santos Mendes Mónico

    Citation: BMC Endocrine Disorders 2017 17:77

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  25. Content type: Research article

    Metabolic syndrome is a cluster of the most dangerous heart attack risk factors such as diabetes and prediabetes, abdominal obesity, high cholesterol and high blood pressure. Hyperuricemia is a condition in wh...

    Authors: Shiferaw Bekele Woyesa, Agete Tadewose Hirigo and Temesgen Bizuayehu Wube

    Citation: BMC Endocrine Disorders 2017 17:76

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  26. Content type: Research article

    Type 2 diabetes is associated with substantial cardiovascular morbidity and mortality arising from the high prevalence of cardiovascular risk factors such as hypertension, dyslipidaemia, obesity, poor glycaemi...

    Authors: Mercy W. Kimando, Frederick C. F. Otieno, Elijah N. Ogola and Kenn Mutai

    Citation: BMC Endocrine Disorders 2017 17:73

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  27. Content type: Research article

    Individuals with Diabetes Mellitus (DM) are at increased risk for fracture due to the decrease in bone strength and quality. Serum procollagen type I intact N-terminal (P1NP) and serum C-terminal cross-linking...

    Authors: Dyah Purnamasari, Melisa D. Puspitasari, Bambang Setiyohadi, Pringgodigdo Nugroho and Harry Isbagio

    Citation: BMC Endocrine Disorders 2017 17:72

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  28. Content type: Research article

    Type 2 diabetes (T2D) is a progressive disease that often requires a patient to use multiple antihyperglycemic agents to achieve glycemic control with disease progression. Omarigliptin is a once-weekly dipepti...

    Authors: Seung-Hwan Lee, Ira Gantz, Elizabeth Round, Melanie Latham, Edward A. O’Neill, Paulette Ceesay, Shailaja Suryawanshi, Keith D. Kaufman, Samuel S. Engel and Eseng Lai

    Citation: BMC Endocrine Disorders 2017 17:70

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  29. Content type: Research article

    Randomized clinical trials have shown the efficacy and safety of short-acting exenatide in patients with type 2 diabetes mellitus (T2DM). The aim of this observational study was to investigate the effectivenes...

    Authors: You-Cheol Hwang, Ari Kim, Euna Jo, Yeoree Yang, Jae-Hyoung Cho and Byung-Wan Lee

    Citation: BMC Endocrine Disorders 2017 17:68

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  30. Content type: Research article

    Adipose tissue, an endocrine organ of the body, is involved in some obesity-related disease states such as insulin resistance, diabetes mellitus, and atherosclerosis. Vaspin is a novel adipocyte with insulin s...

    Authors: Wei Yang, Yun Li, Tian Tian, Li Wang, Pearl Lee and Qi Hua

    Citation: BMC Endocrine Disorders 2017 17:67

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  31. Content type: Research article

    Self-care is essential for patients with diabetes mellitus. Both clinicians and researchers must be able to assess the quality of that self-care. Available tools have various limitations and none are theoretic...

    Authors: Davide Ausili, Claudio Barbaranelli, Emanuela Rossi, Paola Rebora, Diletta Fabrizi, Chiara Coghi, Michela Luciani, Ercole Vellone, Stefania Di Mauro and Barbara Riegel

    Citation: BMC Endocrine Disorders 2017 17:66

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  32. Content type: Research article

    It is well known that dyslipidemia and chronic hyperglycemia increase the onset of diabetes and diabetic complication. The aim of this study is to see the association of trace metals elements and lipid profile...

    Authors: Amare Desalegn Wolide, Belay Zawdie, Tilahun Alemayehu and Samuel Tadesse

    Citation: BMC Endocrine Disorders 2017 17:64

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  33. Content type: Debate

    Insulin treatment has been associated with a paradoxical worsening of diabetes retinopathy since many years in European cohorts. Recently, this issue has been stressed by some studies conducted in other parts ...

    Authors: Ahmadou M. Jingi, Aurel T. Tankeu, Narcisse Assene Ateba and Jean Jacques Noubiap

    Citation: BMC Endocrine Disorders 2017 17:63

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  34. Content type: Research article

    Recent studies have demonstrated that immune factors might have a role in the pathophysiology of insulin resistance and type 2 diabetes mellitus (T2DM). Inappropriate glycemic control in patients with T2DM is ...

    Authors: Muhammed Kizilgul, Ozgur Ozcelik, Selvihan Beysel, Hakan Akinci, Seyfullah Kan, Bekir Ucan, Mahmut Apaydin and Erman Cakal

    Citation: BMC Endocrine Disorders 2017 17:62

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  35. Content type: Research article

    Recent studies show that bile acids are involved in glucose and energy homeostasis through activation of G protein coupled membrane receptor (TGR5) and farnesoid X receptor (FXR). A few researches have explore...

    Authors: Xinfeng Yan, Peicheng Li, Zhaosheng Tang and Bo Feng

    Citation: BMC Endocrine Disorders 2017 17:60

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  36. Content type: Research article

    It has been shown that hepcidin and YKL-40 levels change in persons with insulin resistance in different circumstances. However, variations of the levels of these parameters through the stages of prediabetes a...

    Authors: Driton Vela, Jovica Leshoski, Zana Vela, Muharrem Jakupaj, Mitko Mladenov and Ramadan B. Sopi

    Citation: BMC Endocrine Disorders 2017 17:53

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  37. Content type: Research article

    There are multiple criteria to define remission of type 2 diabetes (DM2) after bariatric surgery but there is not a specific one widely accepted. Our objectives were to compare diagnostic criteria for DM2 remi...

    Authors: María R. Alhambra-Expósito, María J. Molina-Puerta, María I. Prior-Sánchez, Gregorio Manzano-García, Alfonso Calañas-Continente and María A. Gálvez-Moreno

    Citation: BMC Endocrine Disorders 2017 17:51

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  38. Content type: Research article

    Hypoxia inducible factor 1 (HIF-1) activates protective pathways to counteract hypoxia and prevent tissue damage in conjunction with renal injury. The aim of this study was to evaluate a role of HIF-1 in diabe...

    Authors: Romana Bohuslavova, Radka Cerychova, Katerina Nepomucka and Gabriela Pavlinkova

    Citation: BMC Endocrine Disorders 2017 17:48

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  39. Content type: Study protocol

    Diabetes risk is extremely high for Latinos from low-income households. Health guidelines recommend that individuals learn strategies to self-manage their diabetes, but getting people to adopt required lifesty...

    Authors: Janet Page-Reeves, Lidia Regino, Cristina Murray-Krezan, Molly Bleecker, Erik Erhardt, Mark Burge, Elaine Bearer and Shiraz Mishra

    Citation: BMC Endocrine Disorders 2017 17:46

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  40. Content type: Research article

    Type 2 diabetes (T2D) is associated with substantial morbidity and mortality. Individuals with a family history of T2D are at an increased risk of developing the disease. The aim of this study was to assess me...

    Authors: Josefin Henninger, Araz Rawshani, Ann Hammarstedt and Björn Eliasson

    Citation: BMC Endocrine Disorders 2017 17:40

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  41. Content type: Research article

    The metabolic syndrome (MetS) is a clustering of interrelated risk factors which doubles the risk of cardio-vascular disease (CVD) in 5–10 years and increases the risk of type 2 diabetes 5 fold. The identifica...

    Authors: Geoffrey Omuse, Daniel Maina, Mariza Hoffman, Jane Mwangi, Caroline Wambua, Elizabeth Kagotho, Angela Amayo, Peter Ojwang, Zulfiqarali Premji, Kiyoshi Ichihara and Rajiv Erasmus

    Citation: BMC Endocrine Disorders 2017 17:37

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    The Erratum to this article has been published in BMC Endocrine Disorders 2017 17:43

  42. Content type: Research article

    Achieving control of glycated hemoglobin (HbA1c), blood pressure (BP), and body weight (BW) remains a challenge for most patients with type 2 diabetes mellitus (T2DM). In clinical trials, canagliflozin (CANA),...

    Authors: Carol H. Wysham, Patrick Lefebvre, Dominic Pilon, Mike Ingham, Marie-Hélène Lafeuille, Bruno Emond, Rhiannon Kamstra, Wing Chow, Michael Pfeifer and Mei Sheng Duh

    Citation: BMC Endocrine Disorders 2017 17:32

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  43. Content type: Research article

    Evidence suggests disparities in quality of care (QoC) indicators based on sex exist in adults diagnosed with diabetes; however, this research is limited. Therefore, the objective of this research study was to...

    Authors: Joni S. Williams, Kinfe G. Bishu, Alessandra St. Germain and Leonard E. Egede

    Citation: BMC Endocrine Disorders 2017 17:31

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  44. Content type: Research article

    Diabetes registry enables practitioners to measure the characteristics and patterns of diabetes across their patient population. They also provide insight into practice patterns which can be very effective in ...

    Authors: Jaweed Akhter, Asma Ahmed, Minaz Mawani, Laila Lakhani, Ayaz Kalsekar, Shehla Tabassum and Najmul Islam

    Citation: BMC Endocrine Disorders 2017 17:30

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  45. Content type: Research article

    Increased carotid-femoral pulse wave velocity (PWV) has been associated with incident cardiovascular disease, independently of traditional risk factors. Cardiac autonomic dysfunction is a common complication o...

    Authors: Stamatina Chorepsima, Ioanna Eleftheriadou, Anastasios Tentolouris, Ioannis Moyssakis, Athanasios Protogerou, Alexandros Kokkinos, Petros P. Sfikakis and Nikolaos Tentolouris

    Citation: BMC Endocrine Disorders 2017 17:27

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  46. Content type: Study protocol

    Cognitive impairment is common in type 2 diabetes mellitus, and there is a strong association between type 2 diabetes and Alzheimer’s disease. However, we do not know which type 2 diabetes patients will dement...

    Authors: Sheila K. Patel, Carolina Restrepo, Emilio Werden, Leonid Churilov, Elif I. Ekinci, Piyush M. Srivastava, Jay Ramchand, Bryan Wai, Brian Chambers, Christopher J. O’Callaghan, David Darby, Vladimir Hachinski, Toby Cumming, Geoff Donnan, Louise M. Burrell and Amy Brodtmann

    Citation: BMC Endocrine Disorders 2017 17:24

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  47. Content type: Study protocol

    Type 2 diabetes mellitus (T2DM) patients experience many psychosocial problems related to their diabetes. These often lead to emotional disorders such as distress, stress, anxiety and depression, resulting in ...

    Authors: Boon-How Chew, Rimke C. Vos, Sazlina Shariff Ghazali, Nurainul Hana Shamsuddin, Aaron Fernandez, Firdaus Mukhtar, Mastura Ismail, Azainorsuzila Mohd Ahad, Narayanan N. Sundram, Siti Zubaidah Mohd Ali and Guy E. H. M. Rutten

    Citation: BMC Endocrine Disorders 2017 17:22

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  48. Content type: Research article

    Many studies indicated that mean platelet volume (MPV) and platelet distribution width (PDW) may be valuable in the diagnosis and management of clinical disorders; also, serum butyrylcholinesterase activity (B...

    Authors: Suzan Omar Mousa, Samira Zein Sayed, Mahmoud Mohammed Moussa and Ahmed Hamdy Hassan

    Citation: BMC Endocrine Disorders 2017 17:23

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