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Diabetes and Metabolism

Section edited by Abd Tahrani

This section concerns all aspects of diabetes and metabolic syndrome including but not limited to: prevention, diagnosis and management, as well as related molecular genetics, and pathophysiology.

Page 1 of 6

  1. Subclinical diabetic cardiomyopathy (DCM) occurs frequently in asymptomatic subjects with Type 2 diabetes mellitus (T2DM). The direct association between the immune system and DCM with effective biomarkers has...

    Authors: Xiaoli Huang, Zihan Qin, Min Xu, Feifei Zhang, Xiaohong Jiang, Fei Hua and Lichan Tao

    Citation: BMC Endocrine Disorders 2020 20:99

    Content type: Research article

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  2. With the obesity epidemic reaching crisis levels, there has been attention around those who may be resilient to the effects of obesity, termed metabolically healthy obesity (MHO), who initially present without...

    Authors: A. Vusirikala, T. Thomas, N. Bhala, A. A. Tahrani, G. N. Thomas and K. Nirantharakumar

    Citation: BMC Endocrine Disorders 2020 20:96

    Content type: Research article

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  3. A family history of diabetes and family members’ experiences with diabetes may influence individuals’ beliefs and expectations about their own diabetes. No qualitative studies have explored the relationship be...

    Authors: Amy T. Cunningham, Alexzandra T. Gentsch, Amanda M. B. Doty, Geoffrey Mills, Marianna LaNoue, Brendan G. Carr, Judd E. Hollander and Kristin L. Rising

    Citation: BMC Endocrine Disorders 2020 20:95

    Content type: Research article

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  4. Caloric restriction is an effective way to treat Type 2 diabetes (T2D). However, chronic and severe restriction of food intake is difficult to sustain and is known to promote slower metabolism. Intermittent an...

    Authors: Elske L. van den Burg, Marjolein P. Schoonakker, Petra G. van Peet, M. Elske. van den Akker-van Marle, Ko Willems van Dijk, Valter D. Longo, Hildo J. Lamb, Mattijs E. Numans and Hanno Pijl

    Citation: BMC Endocrine Disorders 2020 20:94

    Content type: Study protocol

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  5. The uptake of continuous subcutaneous insulin infusion (CSII) therapy in those with type 1 diabetes varies internationally and is mainly determined by the national healthcare reimbursement systems. The aim of ...

    Authors: Katarzyna Anna Gajewska, Kathleen Bennett, Regien Biesma and Seamus Sreenan

    Citation: BMC Endocrine Disorders 2020 20:92

    Content type: Research article

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  6. After years of decline, the rate of amputations was reported to increase by 50% in the U.S. population between 2009 and 2015. Few studies have examined the most recent trends in hospitalized diabetic foot ulce...

    Authors: Yotsapon Thewjitcharoen, Jeeraphan Sripatpong, Sirinate Krittiyawong, Sriurai Porramatikul, Taweesak Srikummoon, Somkiet Mahaudomporn, Siriwan Butadej, Soontaree Nakasatien and Thep Himathongkam

    Citation: BMC Endocrine Disorders 2020 20:89

    Content type: Research article

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  7. This study aimed to measure the effect of diabetes education using the novel method of “diabetes conversation map (DCM)” as compared to routine counselling (RC) on diabetes management self-efficacy (DMSE) amon...

    Authors: Rubina Qasim, Sarfaraz Masih, Mohammad Tahir Yousafzai, Hakim shah, Abdul Manan, Yousaf Shah, Muhammad Yaqoob, Abida Razzaq, Ajmal Khan and Atiya Rahman Khan Rohilla

    Citation: BMC Endocrine Disorders 2020 20:88

    Content type: Research article

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  8. A well-known metabolic side effect from treatment with glucocorticoids is glucocorticoid-induced diabetes mellitus (GIDM). Guidelines on the management of GIDM in hospitalized patients (in the non-critical car...

    Authors: Carina Kirstine Klarskov, Helga Holm Schultz, Frederik Persson, Tomas Møller Christensen, Thomas Peter Almdal, Ole Snorgaard, Katrine Bagge Hansen, Ulrik Pedersen-Bjergaard and Peter Lommer Kristensen

    Citation: BMC Endocrine Disorders 2020 20:86

    Content type: Study protocol

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  9. Worldwide, the prevalence of insulin resistance ranges from 15.5 to 46.5%, among adults. Lebanon reported one of the highest rates reaching 44.6%. The literature suggests an association between dairy product c...

    Authors: Myriam Fahed, Maya G. Abou Jaoudeh, Samar Merhi, Jocelyne Matar Bou Mosleh, Rachelle Ghadieh, Sibelle Al Hayek and Jessy E. El Hayek Fares

    Citation: BMC Endocrine Disorders 2020 20:85

    Content type: Research article

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  10. Obesity and diabetes are related conditions, the prevalence of which has increased globally in recent years. These conditions have been linked to hypertension and vitamin D deficiency though the nature of the ...

    Authors: Ibrahim Al-Sumaih, Brian Johnston, Michael Donnelly and Ciaran O’Neill

    Citation: BMC Endocrine Disorders 2020 20:81

    Content type: Research article

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  11. Nonalcoholic fatty liver disease (NAFLD) is a multisystem disease that affects the liver and a variety of extra-hepatic organ systems. This study aimed to investigate the relationship between hepatic steatosis...

    Authors: Lijun Hu, Xiaoliang Shao, Chun Qiu, Xiaonan Shao, Xiaosong Wang, Rong Niu and Yuetao Wang

    Citation: BMC Endocrine Disorders 2020 20:75

    Content type: Research article

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  12. We quantified, among diabetic adults, the frequency, costs, and factors associated with visits to the emergency department (EDs) and subsequent hospitalizations for acute hypoglycaemic and hyperglycaemic events.

    Authors: Anita Andreano, Marco Bosio and Antonio Giampiero Russo

    Citation: BMC Endocrine Disorders 2020 20:72

    Content type: Research article

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  13. P-selectin, encoded by SELP, has been implicated as an important molecule in the development of arterial stiffness, consequently leading to vascular complications in T2DM. SELP polymorphisms and increased levels ...

    Authors: Raminderjit Kaur, Jatinder Singh, Rohit Kapoor and Manpreet Kaur

    Citation: BMC Endocrine Disorders 2020 20:70

    Content type: Research article

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  14. Insulin resistance (IR) is a common characteristic of women with polycystic ovary syndrome (PCOS). It has been reported that circulating Fetuin-A levels were associated with IR and type 2 diabetes mellitus (T2...

    Authors: Sha Liu, Wenjing Hu, Yirui He, Ling Li, Hua Liu, Lin Gao, Gangyi Yang and Xin Liao

    Citation: BMC Endocrine Disorders 2020 20:67

    Content type: Research article

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  15. The aim of this study was to estimate the levels of circulating carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) in subjects with gestational diabetes mellitus (GDM) and investigate the rela...

    Authors: Yiming Wu, Zhen Yang, Lingfei Zhu, Qing Su and Li Qin

    Citation: BMC Endocrine Disorders 2020 20:66

    Content type: Research article

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  16. Vitamin D measurement is a composite of vitamin D2 (25(OH)D2) and D3 (25(OH)D3) levels, and its deficiency is associated with the development of type 2 diabetes (T2DM) and diabetic complications; vitamin D defici...

    Authors: Lina H. M. Ahmed, Alexandra E. Butler, Soha R. Dargham, Aishah Latif, Amal Robay, Omar M. Chidiac, Amin Jayyousi, Jassim Al Suwaidi, Ronald G. Crystal, Stephen L. Atkin and Charbel Abi Khalil

    Citation: BMC Endocrine Disorders 2020 20:65

    Content type: Research article

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  17. Glucocorticoid (GC)-induced hyperglycemia is characterized by elevated postprandial blood glucose, which commonly requires multiple insulin injections. We investigated whether a long-acting glucagon-like pepti...

    Authors: Hiroyuki Uchinuma, Masashi Ichijo, Noriyuki Harima and Kyoichiro Tsuchiya

    Citation: BMC Endocrine Disorders 2020 20:58

    Content type: Research article

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  18. The relationship between betatrophin/ANGPTL8 and obesity has been investigated using body mass index (BMI); however, since BMI reflects overall adiposity rather than body fat distribution, it remains unclear w...

    Authors: Jing Zheng, Juan Liu, Beverly S. Hong, Weijian Ke, Minmin Huang and Yanbing Li

    Citation: BMC Endocrine Disorders 2020 20:51

    Content type: Research article

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  19. Diabetes mellitus (DM) is a global health care problem that can impose a substantial economic burden. Diabetic peripheral neuropathy (DPN) is a common microvascular complication of DM that increases the potent...

    Authors: Wondimeneh Shibabaw Shiferaw, Tadesse Yirga Akalu, Yeshamble Work and Yared Asmare Aynalem

    Citation: BMC Endocrine Disorders 2020 20:49

    Content type: Research article

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  20. Diabetic foot ulcers (DFUs) are common problems in diabetes. One of the most important factors affecting the quality of diabetes care is knowledge and practice. The current study aimed at determining the knowl...

    Authors: Aydin Pourkazemi, Atefeh Ghanbari, Monireh Khojamli, Heydarali Balo, Hossein Hemmati, Zakiyeh Jafaryparvar and Behrang Motamed

    Citation: BMC Endocrine Disorders 2020 20:40

    Content type: Research article

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  21. Various guidelines recommend that all adults diagnosed with type 1 diabetes (T1D) should be offered an evidence based, structured education programme (SEP) to optimize self-management care. China has a 13,000 ...

    Authors: Yuting Xie, Fang Liu, Fansu Huang, Chunna Lan, Jia Guo, Jing He, Lezhi Li, Xia Li and Zhiguang Zhou

    Citation: BMC Endocrine Disorders 2020 20:37

    Content type: Research article

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  22. There is evidence of statin benefit among patients with diabetes regardless of cholesterol levels or prior cardiovascular disease history. Despite the evidence, there is under-prescription of statins in clinic...

    Authors: Julius Chacha Mwita, Brian Godman and Tonya M. Esterhuizen

    Citation: BMC Endocrine Disorders 2020 20:36

    Content type: Research article

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  23. Hypoglycemia in type 2 diabetes mellitus (T2DM) is still unsolved issue. The aim of this study was to investigate hypoglycemia in T2DM in participants treated with oral antihyperglycemic agents using different...

    Authors: Maja Baretić and Valeria Bralić Lang

    Citation: BMC Endocrine Disorders 2020 20:35

    Content type: Research article

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  24. In contrast to insulin-dependent type 1 diabetes mellitus (T1DM), the indication for Simultaneous pancreas-kidney transplantation (SPK) in patients with type 2 diabetes mellitus (T2DM) is still ambiguous and w...

    Authors: Hans-Michael Hau, Nora Jahn, Maximilian Brunotte, Andri Arnosson Lederer, Elisabeth Sucher, Franz Maximilian Rasche, Daniel Seehofer and Robert Sucher

    Citation: BMC Endocrine Disorders 2020 20:30

    Content type: Research article

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  25. The number of patients with obesity continues to increase in our society. At the same time, digitalization defines our everyday life. Therefore, the question arises whether to use digital media for effective t...

    Authors: Alexandra Ziegeldorf, Petra Wagner and Hagen Wulff

    Citation: BMC Endocrine Disorders 2020 20:28

    Content type: Research article

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  26. There is still a lack of knowledge on long-term effects of surgical and non-surgical weight-lowering treatments. BASUN is a prospective study with 10 years of follow-up that will observe the effects and conseq...

    Authors: Gudrún Höskuldsdóttir, Karin Mossberg, Ville Wallenius, Angelos Al Nimer, Wiveka Björkvall, Sören Lundberg, Carl-Johan Behre, Malin Werling, Björn Eliasson and Lars Fändriks

    Citation: BMC Endocrine Disorders 2020 20:23

    Content type: Research article

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  27. Currently, bariatric surgery is the most effective treatment for severe obesity and its metabolic complications; however, 15–35% of the patients that undergo bariatric surgery do not reach their goal for weigh...

    Authors: Diego Cadena-Obando, Claudia Ramírez-Rentería, Aldo Ferreira-Hermosillo, Alejandra Albarrán-Sanchez, Ernesto Sosa-Eroza, Mario Molina-Ayala and Etual Espinosa-Cárdenas

    Citation: BMC Endocrine Disorders 2020 20:20

    Content type: Research article

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  28. Strict glycaemic control early in the treatment process has been shown to reduce the occurrence of micro- and macro- vascular complications of diabetes in the long-term. Thus, treatment guidelines advise early...

    Authors: Kyriakos Souliotis, Anastasios Koutsovasilis, Georgia Vatheia, Christina Golna, Sofia Nikolaidi, Erifili Hatziagelaki, Kalliopi Kotsa, Theocharis Koufakis, Andreas Melidonis, Athanasia Papazafiropoulou, Nikolaos Tentolouris, Evangelia Siami and Alexios Sotiropoulos

    Citation: BMC Endocrine Disorders 2020 20:16

    Content type: Research article

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  29. Self- management is vital to the control of diabetes. This study aims to assess the diabetes self-care behaviours of patients attending two tertiary hospitals in Gauteng, South Africa. The study also seeks to ...

    Authors: Chipo Mutyambizi, Milena Pavlova, Charles Hongoro and Wim Groot

    Citation: BMC Endocrine Disorders 2020 20:15

    Content type: Research article

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  30. The risk of colon or breast cancer in metabolically healthy obese (MHO) were lower than that in metabolically abnormal obese (MAO). We hypothesized that the risk of incident gastric cancer in MHO is lower than...

    Authors: Yoshitaka Hashimoto, Masahide Hamaguchi, Akihiro Obora, Takao Kojima and Michiaki Fukui

    Citation: BMC Endocrine Disorders 2020 20:11

    Content type: Research article

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  31. Medically-tailored meal programs that provide home-delivered medically-appropriate food are an emerging intervention when type 2 diabetes co-occurs with food insecurity (limited or uncertain access to nutritio...

    Authors: Seth A. Berkowitz, Naysha N. Shahid, Jean Terranova, Barbara Steiner, Melanie P. Ruazol, Roshni Singh, Linda M. Delahanty and Deborah J. Wexler

    Citation: BMC Endocrine Disorders 2020 20:10

    Content type: Research article

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  32. Although there are numerous studies on the global prevalence of cardiometabolic risk factors (CMRFs) in military personnel, the pooled prevalence of CMRFs in this population remains unclear. We aimed to system...

    Authors: Fereshteh Baygi, Kimmo Herttua, Olaf Chresten Jensen, Shirin Djalalinia, Armita Mahdavi Ghorabi, Hamid Asayesh and Mostafa Qorbani

    Citation: BMC Endocrine Disorders 2020 20:8

    Content type: Research article

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  33. In the United States (U.S.), the prevalence of both diagnosed and undiagnosed type 2 diabetes (T2D) is nearly twice as high among Mexican-origin Hispanic/Latino adults compared to non-Hispanic Whites. Rates of...

    Authors: Jessikah Morales, Namino Glantz, Arianna Larez, Wendy Bevier, Mary Conneely, Ludi Fan, Beverly Reed, Carlos Alatorre, Rosirene Paczkowski, Tamim Ahmed, Andrew Mackenzie, Ian Duncan and David Kerr

    Citation: BMC Endocrine Disorders 2020 20:4

    Content type: Study protocol

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  34. Polycystic ovary syndrome (PCOS) is the most common endocrinopathy in women of reproductive age, characterized by hyperandrogenism, oligomenorrhea, polycystic ovary morphology, and insulin resistance. Vitamin ...

    Authors: Do Kyeong Song, Hyejin Lee, Young Sun Hong and Yeon-Ah Sung

    Citation: BMC Endocrine Disorders 2019 19:145

    Content type: Research article

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  35. The use of immune checkpoint inhibitor (ICI) therapy is becoming a standard of care for several cancers. Monoclonal antibodies targeting cytotoxic T-lymphocyte antigen-4 (CTLA-4) and programmed cell death prot...

    Authors: Marco Zezza, Christophe Kosinski, Carine Mekoguem, Laura Marino, Haithem Chtioui, Nelly Pitteloud and Faiza Lamine

    Citation: BMC Endocrine Disorders 2019 19:144

    Content type: Case report

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  36. Diabetes mellitus causes multiple medical, psychological and sexual problems in both men and women. Sexual dysfunction is one of those problems that lead to a strong social and psychological problem which adve...

    Authors: Adane Asefa, Tadesse Nigussie, Andualem Henok and Yitagesu Mamo

    Citation: BMC Endocrine Disorders 2019 19:141

    Content type: Research article

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  37. Diabetes self-management education can be helpful for patients with type 2 diabetes in managing their condition. We aimed to study the effects of the group-based PRoactive Interdisciplinary Self-MAnagement (PR...

    Authors: Esther du Pon, Nanne Kleefstra, Frits Cleveringa, Ad van Dooren, Eibert R. Heerdink and Sandra van Dulmen

    Citation: BMC Endocrine Disorders 2019 19:139

    Content type: Research article

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  38. To evaluate the impact of treatment with recombinant human growth hormone (rhGH; Omnitrope®) on the risk of diabetes mellitus in adults with growth hormone deficiency (GHD), using data from the ongoing PATRO A...

    Authors: Paolo Beck-Peccoz, Charlotte Höybye, Robert D. Murray, Suat Simsek, Markus Zabransky, Hichem Zouater and Günter Stalla

    Citation: BMC Endocrine Disorders 2019 19:138

    Content type: Research article

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  39. Abdominal obesity and presence of the metabolic syndrome (MetS) significantly increase the risk of developing diseases such as Type 2 diabetes mellitus (T2DM) with escalating emergence of MetS and T2DM constit...

    Authors: Doris Pierce, Lea Merone, Chris Lewis, Tony Rahman, John Croese, Alex Loukas, Malcolm McDonald, Paul Giacomin and Robyn McDermott

    Citation: BMC Endocrine Disorders 2019 19:136

    Content type: Study protocol

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  40. The burden of non-communicable diseases is growing rapidly in low- and middle-income countries. Research suggests that health interventions that aim to improve patient self-management and empower patients to c...

    Authors: Nina Abrahams, Lucy Gilson, Naomi S. Levitt and Joel A. Dave

    Citation: BMC Endocrine Disorders 2019 19:133

    Content type: Research article

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  41. This analysis evaluates the cost-effectiveness of insulin degludec (degludec) versus biosimilar insulin glargine U100 (glargine U100) in patients with type 1 (T1DM) and type 2 diabetes mellitus (T2DM) in Bulga...

    Authors: Monika Russel-Szymczyk, Vasil Valov, Alexandra Savova and Manoela Manova

    Citation: BMC Endocrine Disorders 2019 19:132

    Content type: Research article

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  42. Finding the relationship between the major dietary patterns and cardiometabolic phenotypes could be used for planning prevention programs based on the cultural and dietary habits to prevent transient from a me...

    Authors: Leila Nikniaz, Mahdieh Abbasalizad Farhangi, Jafar Sadegh Tabrizi and Zeinab Nikniaz

    Citation: BMC Endocrine Disorders 2019 19:131

    Content type: Research article

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  43. We measured the concentrations of the adipocytokines vaspin and visfatin in obese Chinese children. Furthermore, we studied the correlation of these adipocytokines with early-onset metabolic and vascular seque...

    Authors: Chunyan Yin, Wei Hu, Ming Wang and Yanfeng Xiao

    Citation: BMC Endocrine Disorders 2019 19:127

    Content type: Research article

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  44. Compositional abnormalities in lipoproteins and cardiovascular risk factors play an important role in the progression of diabetic peripheral neuropathy (DPN). This systematic review aimed to estimate the predi...

    Authors: Syed Shah Zaman Haider Naqvi, Saber Imani, Hossein Hosseinifard, Qing-Lian Wen, M. Naveed Shahzad, Iqra Ijaz, Youcai Deng, Man Guo and Yong Xu

    Citation: BMC Endocrine Disorders 2019 19:125

    Content type: Research article

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  45. Diabetic ketoacidosis (DKA) is an acute, major, life-threatening complication of diabetes that requires immediate treatment. Allergic reaction to insulin is rare, especially when using recombinant human insuli...

    Authors: Anh Dat Nguyen, Chinh Quoc Luong, Hieu Chi Chu, Van Khoa Dieu Nguyen, Chi Van Nguyen, Tuan Anh Nguyen, Quan Huu Nguyen, Ton Duy Mai, Dinh Van Nguyen, Bay Quang Nguyen, Thong Huu Tran, Phuong Viet Dao, Dat Tuan Nguyen, Nguyet Nhu Nguyen and Son Ngoc Do

    Citation: BMC Endocrine Disorders 2019 19:121

    Content type: Case report

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  46. Agenesis of the dorsal pancreas (ADP) is clinically rare, and it is usually accompanied by abdominal pain. Various disorders of glucose metabolism associating with ADP have been reported, but there are only tw...

    Authors: Tian Yang, Xudan Yang, Luping Wang and Jun Mo

    Citation: BMC Endocrine Disorders 2019 19:120

    Content type: Case report

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  47. The shape of the glucose response curve during an oral glucose tolerance test (OGTT) can predict β-cell function and insulin resistance. However, there have been few studies conducted on Chinese people. Thus, ...

    Authors: Xinqi Cheng, Na Yang, Yuxiu Li, Qi Sun, Ling Qiu, Lingling Xu, Fan Ping, Wei Li and Huabing Zhang

    Citation: BMC Endocrine Disorders 2019 19:119

    Content type: Research article

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  48. Diabetes is 7th largest cause of death worldwide, and prevalence is increasing rapidly in low-and middle-income countries. There is an urgent need to develop and test interventions to prevent and control diabe...

    Authors: Joanna Morrison, Kohenour Akter, Hannah Maria Jennings, Tasmin Nahar, Abdul Kuddus, Sanjit Kumer Shaha, Naveed Ahmed, Carina King, Hassan Haghparast-Bidgoli, Anthony Costello, A. K. Azad Khan, Kishwar Azad and Edward Fottrell

    Citation: BMC Endocrine Disorders 2019 19:118

    Content type: Research article

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