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Diabetes and Metabolism

This section concerns all aspects of diabetes and metabolic syndrome including but not limited to: prevention, diagnosis and management, as well as related molecular genetics, and pathophysiology.

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  1. This systematic review aimed to investigate whether diabetes mellitus is a risk factor for low bone density, as this might be important and necessary for doctors specialized in treating patients with low bone ...

    Authors: Jingying Qiu, Chengjiang Li, Zhichun Dong and Jing Wang

    Citation: BMC Endocrine Disorders 2021 21:65

    Content type: Research article

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  2. Diabetes is associated with poor coronavirus disease 2019 (COVID-19) outcomes. However, little is known on the impact of undiagnosed diabetes in the COVID-19 population. We investigated whether diabetes, parti...

    Authors: Ye Liu, Ran Lu, Junhong Wang, Qin Cheng, Ruitao Zhang, Shuisheng Zhang, Yunyi Le, Haining Wang, Wenhua Xiao, Hongwei Gao, Lin Zeng and Tianpei Hong

    Citation: BMC Endocrine Disorders 2021 21:56

    Content type: Research article

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  3. Type 2 diabetes is more frequent in Latin American people than in non-Hispanic whites due to a combination of genetic and lifestyle risk factors. Brazil and Mexico are the most populous countries in Latin Amer...

    Authors: Renata Breda Martins, Sandra Azucena Ordaz-Briseño, Sarahí Flores-Hernández, Ângelo José Gonçalves Bós, Raúl C. Baptista-Rosas and Arieh Roldán Mercado-Sesma

    Citation: BMC Endocrine Disorders 2021 21:48

    Content type: Research article

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  4. NKX6.1 is a transcription factor for insulin, as well as a marker for β cell maturity. Abnormal NKX6.1 expression in β cells, such as translocation from the nucleus to cytoplasm or lost expression, has been sh...

    Authors: Tengli Liu, Peng Sun, Jiaqi Zou, Le Wang, Guanqiao Wang, Na Liu, Yaojuan Liu, Xuejie Ding, Boya Zhang, Rui Liang, Shusen Wang and Zhongyang Shen

    Citation: BMC Endocrine Disorders 2021 21:47

    Content type: Research article

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  5. Home care services plays an important role in diabetes management, and to enable older adults remain home-dwellers. Adequate follow-up and systematic nursing documentation are necessary elements in high qualit...

    Authors: Lovise S. Heimro, Monica Hermann, Therese Thuen Davies, Anne Haugstvedt, Johannes Haltbakk and Marit Graue

    Citation: BMC Endocrine Disorders 2021 21:46

    Content type: Research article

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  6. Type 2 diabetes in the Gulf Cooperation Council countries, including Oman, is currently the fastest growing health crisis and is a significant cause of premature mortality and disability. There is currently in...

    Authors: Adhra Al-Mawali, Ayaman Al-Harrasi, Sathish Kumar Jayapal, Magdi Morsi, Avinash Daniel Pinto, Waleed Al-Shekaili, Hilal Al-Kharusi, Zainab Al-Balushi and John Idikula

    Citation: BMC Endocrine Disorders 2021 21:42

    Content type: Research article

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  7. Gestational diabetes mellitus (GDM) causes many problems for mother and her neonate. A healthy diet plays an important role in preventing GDM. This study aimed to investigate the relationship between major die...

    Authors: Abazar Roustazadeh, Hamed Mir, Sima Jafarirad, Farideh Mogharab, Seyed Ahmad Hosseini, Amir Abdoli and Saiedeh Erfanian

    Citation: BMC Endocrine Disorders 2021 21:41

    Content type: Research article

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  8. Metabolic syndrome (Mets) is prevalent in the general population and has been reported to be an independent risk factor for cognitive impairment. This study aimed to investigate the association of Mets with th...

    Authors: Xiaohui Wang, Long Ji, Zhaoyang Tang, Guoyong Ding, Xueyu Chen, Jian Lv, Yanru Chen and Dong Li

    Citation: BMC Endocrine Disorders 2021 21:40

    Content type: Research article

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  9. This study aimed to develop and validate a nomogram for predicting acute kidney injury (AKI) during the Intensive Care Unit (ICU) stay of patients with diabetic ketoacidosis (DKA).

    Authors: Tingting Fan, Haosheng Wang, Jiaxin Wang, Wenrui Wang, Haifei Guan and Chuan Zhang

    Citation: BMC Endocrine Disorders 2021 21:37

    Content type: Research article

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  10. Insulin resistance (IR) in skeletal muscle is a key feature of the pre-diabetic state, hypertension, dyslipidemia, cardiovascular diseases and also predicts type 2 diabetes. However, the underlying molecular m...

    Authors: Hemang M. Parikh, Targ Elgzyri, Amra Alibegovic, Natalie Hiscock, Ola Ekström, Karl-Fredrik Eriksson, Allan Vaag, Leif C. Groop, Kristoffer Ström and Ola Hansson

    Citation: BMC Endocrine Disorders 2021 21:32

    Content type: Research article

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  11. Studies of drug utilization in patients with diabetes, a chronic disease that can be treated with a wide range of available medicines, have attracted substantial social and clinical interest.

    Authors: Artur Mendes Moura, Sofia Oliveira Martins and João Filipe Raposo

    Citation: BMC Endocrine Disorders 2021 21:30

    Content type: Research article

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  12. Advanced glycation end-products (AGEs) are heterogeneous molecules produced by the non-enzymatic glycation of proteins, lipids, or nucleic acids during hyperglycaemia. Accumulation of AGEs in the peripheral ne...

    Authors: Stella Papachristou, Kalliopi Pafili and Nikolaos Papanas

    Citation: BMC Endocrine Disorders 2021 21:28

    Content type: Review

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  13. Hyperuricemia is associated with insulin resistance, pancreatic β-cell dysfunction and consequently with development of type 2 diabetes. Although a direct relationship between high levels of uric acid (UA) and...

    Authors: Asghar Ghasemi

    Citation: BMC Endocrine Disorders 2021 21:24

    Content type: Review

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  14. Previous studies have indicated inconsistent relationships of diabetes with thyroid cancer risk, yet little is known in China. In this study, we aimed to investigate the associations between diabetes, diabetes...

    Authors: Meng Wang, Wei-Wei Gong, Feng Lu, Ru-Ying Hu, Qing-Fang He and Min Yu

    Citation: BMC Endocrine Disorders 2021 21:21

    Content type: Research article

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  15. The present study aimed to evaluate the effect of artesunate (ART) on the reduction of cardiovascular complications in a type 1 diabetes model and to investigate the associated mechanism based on the receptor ...

    Authors: Yi Chen, Wei Li, Xiaolin Nong, Chen Liang, Jiaquan Li, Wei Lu, Bingge Wang, Zhong Yuan and Shiying Yang

    Citation: BMC Endocrine Disorders 2021 21:19

    Content type: Research article

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  16. Currently, there is a lack of data relating to glycemic parameters and their relationship with C-peptide (CP) and proinsulin (PI) during the partial remission period (PRP) in type 1 diabetes mellitus (T1D). Th...

    Authors: Gül Yeşiltepe-Mutlu, Merve Çapacı, Ecem Can, Tuğba Gökçe, Gizem Bayrakçı, Serra Muradoğlu, Said İncir, Esra Papatya Çakır and Şükrü Hatun

    Citation: BMC Endocrine Disorders 2021 21:18

    Content type: Research article

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  17. Diabetic retinopathy is the most common microvascular complication of diabetes and it is a leading cause of visual impairment and blindness among patients with diabetes. This study aimed to investigate the eff...

    Authors: Seyed Shahriar Hosseini, Mohsen Shamsi, Mahboobeh Khorsandi and Rahmatollah Moradzadeh

    Citation: BMC Endocrine Disorders 2021 21:17

    Content type: Research article

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  18. Skin autofluorescence (SAF) is a non-invasive marker of tissue accumulation of advanced glycation endproducts (AGE). Recently, we demonstrated in the general population that elevated SAF levels predict the dev...

    Authors: Henderikus E. Boersma, Robert P. van Waateringe, Melanie M. van der Klauw, Reindert Graaff, Andrew D. Paterson, Andries J. Smit and Bruce H. R. Wolffenbuttel

    Citation: BMC Endocrine Disorders 2021 21:14

    Content type: Research article

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  19. Weight loss therapy is becoming more and more important, and two classes of molecules, namely amylin receptor and GLP-1 receptor agonists, have shown promise in this regard. Interestingly, these molecules have...

    Authors: Anna Thorsø Larsen, Sofie Gydesen, Nina Sonne, Morten Asser Karsdal and Kim Henriksen

    Citation: BMC Endocrine Disorders 2021 21:10

    Content type: Research article

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  20. Studies analyzing the association between parity and normal-weight metabolic syndrome (MetS) in postmenopausal women of normal weight remain limited, this study aimed to explore the association between parity ...

    Authors: Mengte Shi, Xinhe Zhou, Chao Zheng and Youjin Pan

    Citation: BMC Endocrine Disorders 2021 21:8

    Content type: Research article

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  21. Red cell distribution width (RDW) is a predicter of infections, cancer and diabetes. However, the relationship between RDW and β-cell function and insulin resistance remains unclear in patients with type 2 dia...

    Authors: Deyuan Zhang, Siqi Zhang, Lifang Wang, Tianrong Pan and Xing Zhong

    Citation: BMC Endocrine Disorders 2021 21:7

    Content type: Research article

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  22. Serum uric acid (SUA) is associated with the development of diabetic kidney disease (DKD). Thyroid hormones can regulate metabolism and insulin resistance. The relationship between SUA and thyroid function in ...

    Authors: Xiaomeng Feng, Jing Huang, Yan Peng and Yuan Xu

    Citation: BMC Endocrine Disorders 2021 21:1

    Content type: Research article

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  23. Diabetic ketoacidosis (DKA) and hyperosmolar hyperglycemic state (HHS) are the two most common hyperglycemic emergencies (HEs) associated with diabetes mellitus. Individuals with HEs can present with combined ...

    Authors: Xiao-yan Wu, Dun-min She, Fang Wang, Gang Guo, Ran Li, Ping Fang, Ling Li, Yun Zhou, Ke-qin Zhang and Ying Xue

    Citation: BMC Endocrine Disorders 2020 20:182

    Content type: Research article

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  24. To evaluate the association between diet and disease, the consideration of a whole diet has appeared to be more effective than the examination of single-nutrient intake. This study aimed to examine the relatio...

    Authors: Sahar Golpour-Hamedani, Nahid Rafie, Makan Pourmasoumi, Parvane Saneei and Sayyed Morteza Safavi

    Citation: BMC Endocrine Disorders 2020 20:181

    Content type: Research article

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  25. Existing prevention and treatment strategies target the classic types of diabetes yet this approach might not always be appropriate in some settings where atypical phenotypes exist. This study aims to assess t...

    Authors: Charlotte M. Bavuma, Sanctus Musafiri, Pierre-Claver Rutayisire, Loise M. Ng’ang’a, Ruth McQuillan and Sarah H. Wild

    Citation: BMC Endocrine Disorders 2020 20:180

    Content type: Research article

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  26. Lipid accumulation product (LAP) is a new index based on a combination of waist circumference (WC) and serum triglycerides (TG) reflecting lipid accumulation. In this cross-sectional study, we aimed to explore...

    Authors: Lianqin Dong, Mingzhu Lin, Wengui Wang, Danyan Ma, Yun Chen, Weijuan Su, Zheng Chen, Shunhua Wang, Xuejun Li, Zhibin Li and Changqin Liu

    Citation: BMC Endocrine Disorders 2020 20:179

    Content type: Research article

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  27. Circulating angiopoietin-like 2 (ANGPTL2) protein levels are known to be significantly increased in numerous chronic inflammatory diseases and are associated with the diagnosis and/or prognosis of cardiovascular ...

    Authors: Yan Wang, Zhaohui Zheng, Yuxian Yang, Jianan Lang, Ning Zhang, Longyan Yang and Dong Zhao

    Citation: BMC Endocrine Disorders 2020 20:178

    Content type: Research article

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  28. Individuals with normal weight obesity (NWO) are predisposed to having cardiometabolic disorders. This study aims to investigate the circulating levels of vaspin, leptin and their association with glycemic and...

    Authors: Ehsaneh Taheri, Saeed Hosseini, Mostafa Qorbani and Parvin Mirmiran

    Citation: BMC Endocrine Disorders 2020 20:171

    Content type: Research article

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  29. Metabolic syndrome (MetS) is a major public health concern due to its high prevalence and association with heart disease and diabetes. Artificial neural networks (ANN) are emerging as a reliable means of model...

    Authors: Meysam Eyvazlou, Mahdi Hosseinpouri, Hamidreza Mokarami, Vahid Gharibi, Mehdi Jahangiri, Rosanna Cousins, Hossein-Ali Nikbakht and Abdullah Barkhordari

    Citation: BMC Endocrine Disorders 2020 20:169

    Content type: Research article

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  30. While obesity and overweight status are firmly established risk factors for Type 2 diabetes mellitus (T2DM), a substantial proportion of diabetic individuals, especially in Africa and Asia, are often underweig...

    Authors: Anuradha Rajamanickam, Saravanan Munisankar, Chandra Kumar Dolla, Kannan Thiruvengadam and Subash Babu

    Citation: BMC Endocrine Disorders 2020 20:168

    Content type: Research article

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  31. Despite the current debate about the effects of high intensity interval training (HIIT), HIIT elicits big morpho-physiological benefit on Metabolic Syndrome (MetS) treatment. However, no review or meta-analysi...

    Authors: I. Serrablo-Torrejon, A. Lopez-Valenciano, M. Ayuso, E. Horton, X. Mayo, G. Medina-Gomez, G. Liguori and A. Jimenez

    Citation: BMC Endocrine Disorders 2020 20:167

    Content type: Research article

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  32. Vitamin D deficiency is diagnosed by total serum 25-hydroxyvitamin D (25(OH)D) concentration and is associated with poor health and increased mortality; however, some populations have low 25(OH) D concentratio...

    Authors: Lina H. M. Ahmed, Alexandra E. Butler, Soha R. Dargham, Aishah Latif, Omar M. Chidiac, Stephen L. Atkin and Charbel Abi Khalil

    Citation: BMC Endocrine Disorders 2020 20:161

    Content type: Research article

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  33. Dietary fatty acids are important dietary determinants of metabolic disorders in human. However, it is important to develop an index that considers not only the amount of dietary fatty acids but also the struc...

    Authors: Nika Soltani, Mahdieh Abbasalizad Farhangi, Leila Nikniaz and Mahsa Mahmoudinezhad

    Citation: BMC Endocrine Disorders 2020 20:159

    Content type: Research article

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  34. A growing body of evidence supports neutrophils as having an active role in the development of diabetic kidney disease (DKD). However, the clinical relevance of neutrophils and DKD in autoimmune diabetes remai...

    Authors: Yao Yu, Qiuqiu Lin, Dewei Ye, Yanfei Wang, Binbin He, Yanhua Li, Gan Huang, Zhiguang Zhou and Yang Xiao

    Citation: BMC Endocrine Disorders 2020 20:158

    Content type: Research article

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  35. Follow-up care provided via telemedicine (TM) is intended to be a more integrated care pathway to manage diabetes-related foot ulcers (DFU) than traditionally-delivered healthcare. However, knowledge of the ef...

    Authors: Marjolein M. Iversen, Jannicke Igland, Hilde Smith-Strøm, Truls Østbye, Grethe S. Tell, Svein Skeie, John G. Cooper, Mark Peyrot and Marit Graue

    Citation: BMC Endocrine Disorders 2020 20:157

    Content type: Research article

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  36. Previous studies have suggested that patients with diabetes mellitus (DM) have higher prevalence of atherosclerotic cardiovascular disease (ASCVD), and plasma levels of free fatty acids (FFAs) are a useful mar...

    Authors: Ming-Hua Zhang, Ye-Xuan Cao, Li-Guo Wu, Na Guo, Bing-Jie Hou, Li-Jing Sun, Yuan-Lin Guo, Na-Qiong Wu, Qian Dong and Jian-Jun Li

    Citation: BMC Endocrine Disorders 2020 20:156

    Content type: Research article

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  37. Detailed description of hyperglycemia management in diabetic patients infected with SARS-CoV-2 remain limited, although patients with diabetes show higher complication and mortality rate than patients without ...

    Authors: François R. Jornayvaz, Benjamin Assouline, Jérôme Pugin and Karim Gariani

    Citation: BMC Endocrine Disorders 2020 20:155

    Content type: Case report

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  38. The objectives of this study were to estimate the prevalence of microalbuminuria and examine the association of microalbuminuria with metabolic syndrome (MetS) and its component in a Bangladeshi adult cohort.

    Authors: Muntakim Mahmud Saadi, Manindra Nath Roy, Rubena Haque, Farida Akhter Tania, Shakil Mahmood and Nurshad Ali

    Citation: BMC Endocrine Disorders 2020 20:153

    Content type: Research article

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  39. Metabolic inflammation is an essential event in obesity-induced diabetes and insulin resistance. In obesity, an increasing number of macrophages recruited into visceral adipose tissues undergo significant M1-like...

    Authors: Chaolong Liu, Yanting Yuan, Ji Zhou, Ruixin Hu, Lixia Ji and Guohui Jiang

    Citation: BMC Endocrine Disorders 2020 20:152

    Content type: Research article

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  40. Despite the evidence available on the adverse impact of gestational diabetes (GDM) and thyroid disorders on developing type 2 diabetes (T2DM), the concurrent influence of these disorders on the incidence of T2...

    Authors: Maryam Zahedi, Elham Kazemian, Fahimeh Ramezani-Tehrani, Maryam Tohidi, Fereidoun Azizi, Davood Khalili, Maryam Rahmati and Atieh Amouzegar

    Citation: BMC Endocrine Disorders 2020 20:150

    Content type: Research article

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  41. Worldwide, the epidemiological and demographic transitions have resulted in nutrition shift characterized by an increased consumption of high energy fast food products. In just over 3 decades, overweight and o...

    Authors: Pedro Pallangyo, Zabella S. Mkojera, Naairah R. Hemed, Happiness J. Swai, Nsajigwa Misidai, Lucy Mgopa, Smita Bhalia, Jalack Millinga, Theophil L. Mushi, Lucia Kabeya, Aisha Omar, Alice Kaijage, Rydiness Mulashani, Silvia Mosha, Faustina Mwapinga and Mohamed Janabi

    Citation: BMC Endocrine Disorders 2020 20:147

    Content type: Research article

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  42. The risk of surgical site infection has been reported to be higher in patients with poorly controlled diabetes. Since chronic hyperglycemia impairs neutrophil functions, preoperative glycemic control may resto...

    Authors: Daichi Fujimoto, Yuki Nomura, Moritoki Egi, Norihiko Obata and Satoshi Mizobuchi

    Citation: BMC Endocrine Disorders 2020 20:146

    Content type: Research article

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  43. This study tested the association between serum levels of microRNA-486, −146b and -15b and betatrophin in normal and obese children with/without type 2 diabetes mellitus (T2DM).

    Authors: Khalid M. Mohany, Osamah Al rugaie, Osama Al-wutayd, Abdullah Al-Nafeesah and Tahia H. Saleem

    Citation: BMC Endocrine Disorders 2020 20:145

    Content type: Research article

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  44. The infants born to women who are overweight or obese in pregnancy are at an increased risk of being born macrosomic or large for gestational age. Antenatal dietary and lifestyle interventions have been shown ...

    Authors: Amanda J. Poprzeczny, Jennie Louise, Andrea R. Deussen and Jodie M. Dodd

    Citation: BMC Endocrine Disorders 2020 20:139

    Content type: Research article

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