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Diabetes and Metabolism

Section edited by Abd Tahrani

This section concerns all aspects of diabetes and metabolic syndrome including but not limited to: prevention, diagnosis and management, as well as related molecular genetics, and pathophysiology.

Page 1 of 4

  1. Content type: Research article

    Soluble receptor for advanced glycation end-products (sRAGE) and advanced glycation end-products (AGE) have been associated with risks of cardiovascular disease. Because sRAGE is regarded as a scavenger to AGE...

    Authors: Kuang-Hsing Chiang, Jaw-Wen Chen, Shao-Sung Huang, Hsin-Bang Leu, Shing-Jong Lin and Po-Hsun Huang

    Citation: BMC Endocrine Disorders 2018 18:84

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  2. Content type: Research article

    Poor understanding of diabetes management targets is associated with worse disease outcomes. Patients may use different information than providers to assess their diabetes control. In this study, we identify t...

    Authors: Anjali Gopalan, Katherine Kellom, Kevin McDonough and Marilyn M. Schapira

    Citation: BMC Endocrine Disorders 2018 18:79

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  4. Content type: Research article

    Type 2 diabetes mellitus has become one of the most important public health concerns worldwide. Due to its high prevalence and morbidity, there is an avid necessity to find new therapies that slow the progress...

    Authors: Miguel Ángel Gómez-Sámano, Jorge Enrique Baquerizo-Burgos, Melissa Fabiola Coronel Coronel, Buileng Daniela Wong-Campoverde, Fernando Villanueva-Martinez, Diego Molina-Botello, Jose Alonso Avila-Rojo, Lucía Palacios-Báez, Daniel Cuevas-Ramos, Francisco Javier Gomez-Perez, Alejandro Zentella-Dehesa, Álvaro Aguayo-González and Alfonso Gulias-Herrero

    Citation: BMC Endocrine Disorders 2018 18:77

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  5. Content type: Research article

    Improved glycemic control is the desired outcome after the discharge of patients with diabetes. We aimed to determine the efficacy of a basal-bolus insulin protocol in hospitalized patients with diabetes treat...

    Authors: Elena Chertok Shacham, Hila Kfir, Naama Schwartz and Avraham Ishay

    Citation: BMC Endocrine Disorders 2018 18:75

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  6. Content type: Study protocol

    Health care providers aim to stimulate self-management in type 2 diabetes (T2DM) patients. However, they have a limited number of patient contacts to do this. With the growing number of T2DM patients, innovati...

    Authors: Anne Meike Boels, Guy Rutten, Nicolaas Zuithoff, Ardine de Wit and Rimke Vos

    Citation: BMC Endocrine Disorders 2018 18:74

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  7. Content type: Study protocol

    Little evidence exists on the impact of diabetes risk scores, e.g. on physicians and patient’s behavior, perceived risk of persons, shared-decision making and particularly on patient’s health. The aim of this ...

    Authors: Esther Jacobs, Miguel Tamayo, Joachim Rosenbauer, Matthias B. Schulze, Oliver Kuss and Wolfgang Rathmann

    Citation: BMC Endocrine Disorders 2018 18:72

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  8. Content type: Research article

    When children with type 1 diabetes approach adolescence, they are encouraged to become more involved in diabetes self-management. This study explored the challenges pre-adolescent children encounter when self-...

    Authors: David Rankin, Jeni Harden, Katharine Barnard, Louise Bath, Kathryn Noyes, John Stephen and Julia Lawton

    Citation: BMC Endocrine Disorders 2018 18:71

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  9. Content type: Research article

    This study aimed to examine the switch from glargine+once daily insulin aspart (1 + 1 regimen) to glargine+insulin aspart 30 before breakfast combined with exercise and in patients with type 2 diabetes mellitu...

    Authors: Jing Li, Liming Wang, Fen Chen, Dongxia Xia and Lingling Miao

    Citation: BMC Endocrine Disorders 2018 18:69

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  10. Content type: Research article

    Metabolic syndrome (MetS) includes obesity, diabetes, dyslipidemia and hypertension. Its incidence is rapidly increasing worldwide, particularly in postmenopausal women. Estrogens regulate glucose homeostasis ...

    Authors: Lingxia Zhao, Xuemei Fan, Lin Zuo, Qiang Guo, Xiaole Su, Guangxia Xi, Ziyan Zhang, Jianlin Zhang and Guoping Zheng

    Citation: BMC Endocrine Disorders 2018 18:65

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  11. Content type: Research article

    The aim of this study was to assess inadequate glycaemic control and its associated factors among people with type 2 diabetes in Saudi Arabia.

    Authors: Mohammed J. Alramadan, Dianna J. Magliano, Turky H. Almigbal, Mohammed Ali Batais, Afsana Afroz, Hesham J. Alramadhan, Waad Faozi Mahfoud, Adel Mehmas Alragas and Baki Billah

    Citation: BMC Endocrine Disorders 2018 18:62

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  12. Content type: Study protocol

    Type 2 diabetes is a serious clinical problem in both India and the UK. Adoption of a healthy lifestyle through dietary and physical activity modification can help prevent type 2 diabetes. However, implementin...

    Authors: Hazel Thomson, Nick Oliver, Ian F. Godsland, Ara Darzi, Weerachai Srivanichakorn, Azeem Majeed, Desmond G. Johnston, Arun Nanditha, Chamukuttan Snehalatha, Arun Raghavan, Priscilla Susairaj, Mary Simon, Krishnamoorthy Satheesh, Ambady Ramachandran, Stephen Sharp, Kate Westgate…

    Citation: BMC Endocrine Disorders 2018 18:63

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  13. Content type: Research article

    The aim of the present study is to evaluate the association between BMD and type 2 DM status in middle-aged and elderly men. To investigate a possible correlation, the present study used the BMD dataset of the...

    Authors: Miso Jang, Hyunkyung Kim, Shorry Lea, Sohee Oh, Jong Seung Kim and Bumjo Oh

    Citation: BMC Endocrine Disorders 2018 18:61

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  14. Content type: Research article

    Galactomannan(s) are plant-derived fiber shown to reduce post-prandial blood glucose by delaying intestinal absorption of carbohydrates and slowing down gastric emptying. We examined glucose-lowering effects o...

    Authors: Andrea O. Y. Luk, Benny C. Y. Zee, Marc Chong, Risa Ozaki, Carl W. Rausch, Michael H. M. Chan, Ronald C. W. Ma, Alice P. S. Kong, Francis C. C. Chow and Juliana C. N. Chan

    Citation: BMC Endocrine Disorders 2018 18:59

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  16. Content type: Research article

    Type 1 diabetes mellitus (T1DM) is one of the most common chronic diseases in children. Studies on costs related to T1DM are scarce and focused primarily on the costs directly related to diabetes. We aimed to ...

    Authors: E. A. J. M. Spaans, P. R. van Dijk, K. H. Groenier, P. L. P. Brand, N. Kleefstra and H. J. G. Bilo

    Citation: BMC Endocrine Disorders 2018 18:57

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  17. Content type: Research article

    The shapes of the plasma glucose concentration curve during the oral glucose tolerance test are related to different metabolic risk profiles and future risk of type 2 DM. We sought to further analyze the relat...

    Authors: Leonardo de Andrade Mesquita, Luciana Pavan Antoniolli, Giordano Fabricio Cittolin-Santos and Fernando Gerchman

    Citation: BMC Endocrine Disorders 2018 18:56

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  18. Content type: Research article

    Diabetic foot ulceration is a serious limb-threatening complication of diabetes. It is the common cause of hospital admissions and amputations.

    Authors: Bilal Bin Younis, Adeela Shahid, Rozina Arshad, Saima Khurshid, Muhammad Ahmad and Haroon Yousaf

    Citation: BMC Endocrine Disorders 2018 18:53

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  19. Content type: Research article

    To compare the accuracy of different obesity indexes, including waist circumference (WC), weight-to-height ratio (WHtR), body mass index (BMI), and lipid accumulation product (LAP), in predicting metabolic syn...

    Authors: Leilei Liu, Yu Liu, Xizhuo Sun, Zhaoxia Yin, Honghui Li, Kunpeng Deng, Xu Chen, Cheng Cheng, Xinping Luo, Ming Zhang, Linlin Li, Lu Zhang, Bingyuan Wang, Yongcheng Ren, Yang Zhao, Dechen Liu…

    Citation: BMC Endocrine Disorders 2018 18:54

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  20. Content type: Research article

    Type 2 Diabetes Mellitus is a serious metabolic disease that is often associated with vascular complications. There are 1.9 million people living with Diabetes in Ethiopia; diabetes mellitus is found to be the...

    Authors: Haileab Fekadu Wolde, Asrat Atsedeweyen, Addisu Jember, Tadesse Awoke, Malede Mequanent, Adino Tesfahun Tsegaye and Shitaye Alemu

    Citation: BMC Endocrine Disorders 2018 18:52

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  21. Content type: Research article

    Glycaemic control is one of the most effective strategies for the treatment of diabetes-related erectile dysfunction (DMED). Compared to conventional anti-diabetic drugs and insulin, islet transplantation is m...

    Authors: Zhigang Wu, Hongwei Wang, Fubiao Ni, Xuan Jiang, Ziqiang Xu, Chengyang Liu, Yong Cai, Hongxing Fu, Jiao Luo, Wenwei Chen, Bicheng Chen and Zhixian Yu

    Citation: BMC Endocrine Disorders 2018 18:49

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  22. Content type: Research article

    Diabetes in the United States has reached epidemic proportions and the people of Appalachia have been disproportionately affected by this disease. Strategies that complement standard diabetes care are critical...

    Authors: Elizabeth A. Beverly, Jane Hamel-Lambert, Laura L. Jensen, Sue Meeks and Anne Rubin

    Citation: BMC Endocrine Disorders 2018 18:50

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  23. Content type: Research article

    Optimal glycaemia, reflected by glycated haemoglobin (HbA1c) levels, is key in reducing type 2 diabetes (T2D) complications. However, most people with T2D have suboptimal recall and understanding of HbA1c. Con...

    Authors: Mei Lyn Tan, Jo-Anne Manski-Nankervis, Sharmala Thuraisingam, Alicia Jenkins, David O’Neal and John Furler

    Citation: BMC Endocrine Disorders 2018 18:47

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  24. Content type: Research article

    The benefit results of postoperative tight glycemic control (TGC) were controversial and there was a lack of well-powered studies that support current guideline recommendations.

    Authors: Yuan-yuan Wang, Shuang-fei Hu, Hui-min Ying, Long Chen, Hui-li Li, Fang Tian and Zhen-feng Zhou

    Citation: BMC Endocrine Disorders 2018 18:42

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  25. Content type: Research article

    The prevalence of childhood obesity and obesity-related metabolic disorder such as dyslipidemia has sharply increased in the past few decades. Chronic low-grade inflammation is associated with the development ...

    Authors: Yuesheng Liu, Dong Xu, Chunyan Yin, Sisi Wang, Min Wang and Yanfeng Xiao

    Citation: BMC Endocrine Disorders 2018 18:39

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  26. Content type: Research article

    Hypoglycaemia is a feared experience for people with diabetes. We aimed to study the prevalence and causes of hypoglycaemia among Sri Lankans with diabetes.

    Authors: H. A. Dissanayake, G. S. P. Keerthisena, K. K. K. Gamage, J. H. Liyanage, I. R. H. S. Ihalagama, W. M. U. A. Wijetunga, T. A. D. Tillekaratne, G. W. Katulanda and P. Katulanda

    Citation: BMC Endocrine Disorders 2018 18:35

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  27. Content type: Research article

    Diabetes mellitus is one of the most prevalent diseases worldwide. Diabetes is a chronic disease associated with micro- and macro-vascular complications and deterioration in general health status. Therefore, t...

    Authors: Masoud Behzadifar, Rahim Sohrabi, Roghayeh Mohammadibakhsh, Morteza Salemi, Sharare Taheri Moghadam, Masood Taheri Mirghaedm, Meysam Behzadifar, Hamid Reza Baradaran and Nicola Luigi Bragazzi

    Citation: BMC Endocrine Disorders 2018 18:34

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  28. Content type: Research article

    There is evidence that disparities exist in diabetes prevalence, access to diabetes care, diabetes-related complications, and the quality of diabetes care. A wide range of interventions has been implemented an...

    Authors: Natalie Terens, Simona Vecchi, Anna Maria Bargagli, Nera Agabiti, Zuzana Mitrova, Laura Amato and Marina Davoli

    Citation: BMC Endocrine Disorders 2018 18:31

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  29. Content type: Research article

    Diabetes mellitus is usually preceded by a pre-diabetic stage before the clinical presentation of the disease, the influence of which on persons’ quality of life is not adequately elucidated. The purpose of th...

    Authors: Konstantinos Makrilakis, Stavros Liatis, Afroditi Tsiakou, Chryssoula Stathi, Eleftheria Papachristoforou, Despoina Perrea, Nicholas Katsilambros, Nikolaos Kontodimopoulos and Dimitrios Niakas

    Citation: BMC Endocrine Disorders 2018 18:32

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  30. Content type: Case report

    The diagnosis of atypical non-autoimmune forms of diabetes mellitus, such as maturity onset diabetes of the young (MODY) presents several challenges, in view of the extensive clinical and genetic heterogeneity...

    Authors: Nikolai Paul Pace, Johann Craus, Alex Felice and Josanne Vassallo

    Citation: BMC Endocrine Disorders 2018 18:28

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  31. Content type: Research article

    Retinol binding protein 4 (RBP4), a protein secreted by adipocytes and bound in plasma to transthyretin (TTR), has been associated with obesity, the early phase of insulin resistance, metabolic syndrome, and t...

    Authors: Karunee Kwanbunjan, Pornpimol Panprathip, Chanchira Phosat, Noppanath Chumpathat, Naruemon Wechjakwen, Somchai Puduang, Ratchada Auyyuenyong, Ina Henkel and Florian J. Schweigert

    Citation: BMC Endocrine Disorders 2018 18:26

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  32. Content type: Case report

    Here, we report a case of central pontine demyelinization in a type-2 diabetes patient with hyperglycemia after a binge-eating attack in the absence of a relevant hyponatremia.

    Authors: Rainer U. Pliquett, Arno Noll, Richard Ibe, Alexandra Katz, Charlotte Ackmann, Alexandra Schreiber and Matthias Girndt

    Citation: BMC Endocrine Disorders 2018 18:18

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  33. Content type: Research article

    The evaluation of metabolic syndrome in a society predisposed to the diabetes mellitus epidemic opens a new avenue to understanding this rapidly growing global metabolic problem. Although Saudi Arabia reports ...

    Authors: Khalid Al-Rubeaan, Nahla Bawazeer, Yousuf Al Farsi, Amira M. Youssef, Abdulrahman A. Al-Yahya, Hamid AlQumaidi, Basim M. Al-Malki, Khalid A. Naji, Khalid Al-Shehri and Fahd I. Al Rumaih

    Citation: BMC Endocrine Disorders 2018 18:16

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  34. Content type: Research article

    Impaired insulin activity in women with polycystic ovary syndrome might differ from that seen in type 2 diabetes mellitus without polycystic ovary syndrome. This study was designed to compare the effects of tr...

    Authors: Tao Tao, Peihong Wu, Yuying Wang and Wei Liu

    Citation: BMC Endocrine Disorders 2018 18:14

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  35. Content type: Research article

    Continuous glucose monitoring (CGM) enables users to view real-time interstitial glucose readings and provides information on the direction and rate of change of blood glucose levels. Users can also access his...

    Authors: J. Lawton, M. Blackburn, J. Allen, F. Campbell, D. Elleri, L. Leelarathna, D. Rankin, M. Tauschmann, H. Thabit and R. Hovorka

    Citation: BMC Endocrine Disorders 2018 18:12

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  36. Content type: Research article

    Limited real-world data are currently available on hypoglycemia in diabetes patients. The International Operations Hypoglycemia Assessment Tool (IO HAT) study was designed to estimate hypoglycemia in insulin-t...

    Authors: Rıfat Emral, Tamer Tetiker, Ibrahim Sahin, Ramazan Sari, Ahmet Kaya, İlhan Yetkin, Sefika Uslu Cil and Neslihan Başcıl Tütüncü

    Citation: BMC Endocrine Disorders 2018 18:9

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  37. Content type: Research article

    Increased knowledge concerning the differences in the illness perception and self-management among sexes is needed for planning proper support programs for patients with diabetes. The aim of this study was to ...

    Authors: Wimonrut Boonsatean, Anna Carlsson, Irena Dychawy Rosner and Margareta Östman

    Citation: BMC Endocrine Disorders 2018 18:5

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  38. Content type: Research article

    This retrospective study investigated the effect of adding metformin to pharmacologic insulin dosing in type 1 diabetics on insulin therapy 1 year after treatment compared with patients on insulin therapy alone.

    Authors: Selvihan Beysel, Ilknur Ozturk Unsal, Muhammed Kizilgul, Mustafa Caliskan, Bekir Ucan and Erman Cakal

    Citation: BMC Endocrine Disorders 2018 18:1

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  39. Content type: Research article

    Diabetes is one of the most common metabolic disorders, with a high prevalence of patients with poor metabolic control. Worldwide, evidence highlights the importance of developing and implementing educational ...

    Authors: Maria do Rosário Pinto, Pedro Miguel Dinis Santos Parreira, Marta Lima Basto and Lisete dos Santos Mendes Mónico

    Citation: BMC Endocrine Disorders 2017 17:77

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  40. Content type: Research article

    Metabolic syndrome is a cluster of the most dangerous heart attack risk factors such as diabetes and prediabetes, abdominal obesity, high cholesterol and high blood pressure. Hyperuricemia is a condition in wh...

    Authors: Shiferaw Bekele Woyesa, Agete Tadewose Hirigo and Temesgen Bizuayehu Wube

    Citation: BMC Endocrine Disorders 2017 17:76

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  41. Content type: Research article

    Type 2 diabetes is associated with substantial cardiovascular morbidity and mortality arising from the high prevalence of cardiovascular risk factors such as hypertension, dyslipidaemia, obesity, poor glycaemi...

    Authors: Mercy W. Kimando, Frederick C. F. Otieno, Elijah N. Ogola and Kenn Mutai

    Citation: BMC Endocrine Disorders 2017 17:73

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  42. Content type: Research article

    Individuals with Diabetes Mellitus (DM) are at increased risk for fracture due to the decrease in bone strength and quality. Serum procollagen type I intact N-terminal (P1NP) and serum C-terminal cross-linking...

    Authors: Dyah Purnamasari, Melisa D. Puspitasari, Bambang Setiyohadi, Pringgodigdo Nugroho and Harry Isbagio

    Citation: BMC Endocrine Disorders 2017 17:72

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  43. Content type: Research article

    Type 2 diabetes (T2D) is a progressive disease that often requires a patient to use multiple antihyperglycemic agents to achieve glycemic control with disease progression. Omarigliptin is a once-weekly dipepti...

    Authors: Seung-Hwan Lee, Ira Gantz, Elizabeth Round, Melanie Latham, Edward A. O’Neill, Paulette Ceesay, Shailaja Suryawanshi, Keith D. Kaufman, Samuel S. Engel and Eseng Lai

    Citation: BMC Endocrine Disorders 2017 17:70

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  44. Content type: Research article

    Randomized clinical trials have shown the efficacy and safety of short-acting exenatide in patients with type 2 diabetes mellitus (T2DM). The aim of this observational study was to investigate the effectivenes...

    Authors: You-Cheol Hwang, Ari Kim, Euna Jo, Yeoree Yang, Jae-Hyoung Cho and Byung-Wan Lee

    Citation: BMC Endocrine Disorders 2017 17:68

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  45. Content type: Research article

    Adipose tissue, an endocrine organ of the body, is involved in some obesity-related disease states such as insulin resistance, diabetes mellitus, and atherosclerosis. Vaspin is a novel adipocyte with insulin s...

    Authors: Wei Yang, Yun Li, Tian Tian, Li Wang, Pearl Lee and Qi Hua

    Citation: BMC Endocrine Disorders 2017 17:67

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  46. Content type: Research article

    Self-care is essential for patients with diabetes mellitus. Both clinicians and researchers must be able to assess the quality of that self-care. Available tools have various limitations and none are theoretic...

    Authors: Davide Ausili, Claudio Barbaranelli, Emanuela Rossi, Paola Rebora, Diletta Fabrizi, Chiara Coghi, Michela Luciani, Ercole Vellone, Stefania Di Mauro and Barbara Riegel

    Citation: BMC Endocrine Disorders 2017 17:66

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  47. Content type: Research article

    It is well known that dyslipidemia and chronic hyperglycemia increase the onset of diabetes and diabetic complication. The aim of this study is to see the association of trace metals elements and lipid profile...

    Authors: Amare Desalegn Wolide, Belay Zawdie, Tilahun Alemayehu and Samuel Tadesse

    Citation: BMC Endocrine Disorders 2017 17:64

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  48. Content type: Debate

    Insulin treatment has been associated with a paradoxical worsening of diabetes retinopathy since many years in European cohorts. Recently, this issue has been stressed by some studies conducted in other parts ...

    Authors: Ahmadou M. Jingi, Aurel T. Tankeu, Narcisse Assene Ateba and Jean Jacques Noubiap

    Citation: BMC Endocrine Disorders 2017 17:63

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  49. Content type: Research article

    Recent studies have demonstrated that immune factors might have a role in the pathophysiology of insulin resistance and type 2 diabetes mellitus (T2DM). Inappropriate glycemic control in patients with T2DM is ...

    Authors: Muhammed Kizilgul, Ozgur Ozcelik, Selvihan Beysel, Hakan Akinci, Seyfullah Kan, Bekir Ucan, Mahmut Apaydin and Erman Cakal

    Citation: BMC Endocrine Disorders 2017 17:62

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  50. Content type: Research article

    Recent studies show that bile acids are involved in glucose and energy homeostasis through activation of G protein coupled membrane receptor (TGR5) and farnesoid X receptor (FXR). A few researches have explore...

    Authors: Xinfeng Yan, Peicheng Li, Zhaosheng Tang and Bo Feng

    Citation: BMC Endocrine Disorders 2017 17:60

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