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Diabetes and Metabolism

This section concerns all aspects of diabetes and metabolic syndrome including but not limited to: prevention, diagnosis and management, as well as related molecular genetics, and pathophysiology.

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  1. Worldwide, the epidemiological and demographic transitions have resulted in nutrition shift characterized by an increased consumption of high energy fast food products. In just over 3 decades, overweight and o...

    Authors: Pedro Pallangyo, Zabella S. Mkojera, Naairah R. Hemed, Happiness J. Swai, Nsajigwa Misidai, Lucy Mgopa, Smita Bhalia, Jalack Millinga, Theophil L. Mushi, Lucia Kabeya, Aisha Omar, Alice Kaijage, Rydiness Mulashani, Silvia Mosha, Faustina Mwapinga and Mohamed Janabi

    Citation: BMC Endocrine Disorders 2020 20:147

    Content type: Research article

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  2. The risk of surgical site infection has been reported to be higher in patients with poorly controlled diabetes. Since chronic hyperglycemia impairs neutrophil functions, preoperative glycemic control may resto...

    Authors: Daichi Fujimoto, Yuki Nomura, Moritoki Egi, Norihiko Obata and Satoshi Mizobuchi

    Citation: BMC Endocrine Disorders 2020 20:146

    Content type: Research article

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  3. This study tested the association between serum levels of microRNA-486, −146b and -15b and betatrophin in normal and obese children with/without type 2 diabetes mellitus (T2DM).

    Authors: Khalid M. Mohany, Osamah Al rugaie, Osama Al-wutayd, Abdullah Al-Nafeesah and Tahia H. Saleem

    Citation: BMC Endocrine Disorders 2020 20:145

    Content type: Research article

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  4. The infants born to women who are overweight or obese in pregnancy are at an increased risk of being born macrosomic or large for gestational age. Antenatal dietary and lifestyle interventions have been shown ...

    Authors: Amanda J. Poprzeczny, Jennie Louise, Andrea R. Deussen and Jodie M. Dodd

    Citation: BMC Endocrine Disorders 2020 20:139

    Content type: Research article

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  5. Diabetes is a serious chronic disease. Medical treatment and good psychosocial support are needed to cope with acute and long-term effects of diabetes. Self-management is a large part of diabetes management, w...

    Authors: Elisabet Nerpin, Eva Toft, Johan Fischier, Anna Lindholm-Olinder and Janeth Leksell

    Citation: BMC Endocrine Disorders 2020 20:137

    Content type: Study protocol

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  6. Previous studies have shown the negative impact of sleep disturbances, specifically insomnia symptoms, on glucose metabolism for people with type 2 diabetes (T2D). People with insomnia symptoms are at risk of ...

    Authors: Mohammed M. Alshehri, Shaima A. Alothman, Aqeel M. Alenazi, Jason L. Rucker, Milind A. Phadnis, John M. Miles, Catherine F. Siengsukon and Patricia M. Kluding

    Citation: BMC Endocrine Disorders 2020 20:136

    Content type: Research article

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  7. Euthyroid sick syndrome (ESS) frequently arises in children admitted with diabetic ketoacidosis/diabetic ketosis (DKA/DK). This study evaluates the interplay of various metabolic factors with occurrence of der...

    Authors: Peng Shao, Shujuan Guo, Guimei Li, Daogang Qin, Sen Li and Ying Luan

    Citation: BMC Endocrine Disorders 2020 20:135

    Content type: Research article

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  8. Diabetic foot ulcers (DFU) are associated with high morbidity and mortality globally. Mortality in patients hospitalized for DFU in Nigeria is unacceptably high. This study was undertaken to determine factors ...

    Authors: Olufunmilayo O. Adeleye, Ejiofor T. Ugwu, Ibrahim D. Gezawa, Innocent Okpe, Ignatius Ezeani and Marcelina Enamino

    Citation: BMC Endocrine Disorders 2020 20:134

    Content type: Research article

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  9. Although important achievements have been done in type 2 diabetes mellitus (T2D) treatment and glycemic control, new strategies may take advantage of non-pharmacological approaches and of other potential deter...

    Authors: Rubén Silva-Tinoco, Teresa Cuatecontzi-Xochitiotzi, Viridiana De la Torre-Saldaña, Enrique León-García, Javier Serna-Alvarado, Arturo Orea-Tejeda, Lilia Castillo-Martínez, Juan G. Gay, David Cantú-de-León and Diddier Prada

    Citation: BMC Endocrine Disorders 2020 20:130

    Content type: Research article

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  10. Diabetic foot is an underestimated and redoubtable diabetes complication. The aims of our study were to assess diabetic foot ulcer risk factors according to International Working Group on the Diabetic Foot (IW...

    Authors: B. Zantour, S. Bouchareb, Z. El Ati, F. Boubaker, W. Alaya, W. Kossomtini and M. H. Sfar

    Citation: BMC Endocrine Disorders 2020 20:128

    Content type: Research article

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  11. Fulminant type 1 diabetes mellitus (FT1D) is a newly established subtype of type 1 diabetes. Its etiology has not been fully elucidated. Several cases with FT1D have exhibited pancreatitis or myocarditis.

    Authors: Fujiko Egashira, Midori Kawashima, Ai Morikawa, Minami Kosuda, Hisamitsu Ishihara and Kentaro Watanabe

    Citation: BMC Endocrine Disorders 2020 20:127

    Content type: Case report

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  12. Diabetes is a leading cause of Medicare spending; predicting which individuals are likely to be costly is essential for targeting interventions. Current approaches generally focus on composite measures, short ...

    Authors: Julie C. Lauffenburger, Mufaddal Mahesri and Niteesh K. Choudhry

    Citation: BMC Endocrine Disorders 2020 20:125

    Content type: Research article

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  13. Modern imaging plays a central role in the care of obese patients, and there is an integral focus on its use and accessibility in individuals who have alterations of various in various organs. The objective in...

    Authors: Alejandra Martínez Coria, Norma Angélica Estrada-Cruz, María Inés Pérez Ordoñez, Daniel H. Montes-Cortes and Leticia Manuel-Apolinar

    Citation: BMC Endocrine Disorders 2020 20:124

    Content type: Research article

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  14. Type 1 Diabetes (T1D) is a T cell-mediated autoimmune disorder caused by the destruction of insulin-secreting cells. B7-H3 (CD276) plays a vital role in T cell response. However, B7-H3 expression and its clini...

    Authors: Sisi Ding, Yimei Shan, Lili Sun, Sicheng Li, Rong Jiang, Xin Chang, Ziyi Huang, Jing Sun, Cuiping Liu, Chen Fang and Xueguang Zhang

    Citation: BMC Endocrine Disorders 2020 20:123

    Content type: Research article

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  15. The prevalence of type 2 diabetes mellitus (T2DM) is expected to increase from 7.7% in 2017 to 8.4% in 2045 worldwide. Diabetes complications contribute to morbidity and mortality. To evaluate whether the diab...

    Authors: Hyunju Yoo, Eunjung Choo and Sukhyang Lee

    Citation: BMC Endocrine Disorders 2020 20:122

    Content type: Research article

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  16. The association between the polymorphisms in the vitamin D receptor (VDR) gene and the risk of type 1 diabetes mellitus (T1DM) has been evaluated in several studies. However, the findings were inconclusive. Thus,...

    Authors: Na Zhai, Ramtin Bidares, Masoud Hassanzadeh Makoui, Saeed Aslani, Payam Mohammadi, Bahman Razi, Danyal Imani, Mohammad Yazdchi and Haleh Mikaeili

    Citation: BMC Endocrine Disorders 2020 20:121

    Content type: Research article

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  17. Albuminuria is the early manifestation of the pathogenesis of diabetic nephropathy (DN). The current study was to investigate the relationship of pulmonary function with albuminuria in type 2 diabetic patients...

    Authors: Yun-Yun He, Zhe Chen, Xiang-Yang Fang, Jing Chang, Yong Lu and Xiao-Juan Wang

    Citation: BMC Endocrine Disorders 2020 20:112

    Content type: Research article

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  18. Type 2 diabetes mellitus (T2D) is the most frequent type of diabetes. It has a multifactorial etiology, affecting millions of people worldwide. Ghrelin gene (GHRL) encodes the ghrelin peptide, which promotes food...

    Authors: Edgar Alfonso Rivera-León, Mara Anaís Llamas-Covarrubias, Sergio Sánchez-Enríquez, Erika Martínez-López, Mercedes González-Hita and Iris Monserrat Llamas-Covarrubias

    Citation: BMC Endocrine Disorders 2020 20:109

    Content type: Research article

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  19. Zonulin is a biomarker of impaired intestinal permeability, which has been associated with various disorders. The primary aim was to study serum zonulin (s-zonulin) in individuals with morbid obesity before an...

    Authors: Martin Aasbrenn, Stian Lydersen and Per G Farup

    Citation: BMC Endocrine Disorders 2020 20:108

    Content type: Research article

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  20. Some previous studies have reported inconsistent results on the association between alcohol intake and diabetic retinopathy (DR) risk. This study aimed to evaluate the potential effects of alcohol intake on su...

    Authors: Chen Chen, Zhaojun Sun, Weigang Xu, Jun Tan, Dan Li, Yiting Wu, Ting Zheng and Derong Peng

    Citation: BMC Endocrine Disorders 2020 20:106

    Content type: Research article

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  21. To evaluate the association between high-sensitivity C-reactive protein (hsCRP) and erythrocyte sedimentation rate (ESR), and diabetic kidney disease (DKD) in patients with type 2 diabetes mellitus (T2DM).

    Authors: Shizhe Guo, Meng Wang, Yifei Yu, Yeping Yang, Fangfang Zeng, Fei Sun, Qin Li, Min He, Yiming Li, Jie Wen, Wei Gong and Zhaoyun Zhang

    Citation: BMC Endocrine Disorders 2020 20:103

    Content type: Research article

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  22. The associations between sociodemographic factors and HbA1c variability in type 2 diabetes are not yet established. Examining group differences in HbA1c variability may help identify patient characteristics re...

    Authors: Emelia Mellergård, Per Johnsson and Frida Eek

    Citation: BMC Endocrine Disorders 2020 20:102

    Content type: Research article

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  23. Subclinical diabetic cardiomyopathy (DCM) occurs frequently in asymptomatic subjects with Type 2 diabetes mellitus (T2DM). The direct association between the immune system and DCM with effective biomarkers has...

    Authors: Xiaoli Huang, Zihan Qin, Min Xu, Feifei Zhang, Xiaohong Jiang, Fei Hua and Lichan Tao

    Citation: BMC Endocrine Disorders 2020 20:99

    Content type: Research article

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  24. With the obesity epidemic reaching crisis levels, there has been attention around those who may be resilient to the effects of obesity, termed metabolically healthy obesity (MHO), who initially present without...

    Authors: A. Vusirikala, T. Thomas, N. Bhala, A. A. Tahrani, G. N. Thomas and K. Nirantharakumar

    Citation: BMC Endocrine Disorders 2020 20:96

    Content type: Research article

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  25. A family history of diabetes and family members’ experiences with diabetes may influence individuals’ beliefs and expectations about their own diabetes. No qualitative studies have explored the relationship be...

    Authors: Amy T. Cunningham, Alexzandra T. Gentsch, Amanda M. B. Doty, Geoffrey Mills, Marianna LaNoue, Brendan G. Carr, Judd E. Hollander and Kristin L. Rising

    Citation: BMC Endocrine Disorders 2020 20:95

    Content type: Research article

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  26. Caloric restriction is an effective way to treat Type 2 diabetes (T2D). However, chronic and severe restriction of food intake is difficult to sustain and is known to promote slower metabolism. Intermittent an...

    Authors: Elske L. van den Burg, Marjolein P. Schoonakker, Petra G. van Peet, M. Elske. van den Akker-van Marle, Ko Willems van Dijk, Valter D. Longo, Hildo J. Lamb, Mattijs E. Numans and Hanno Pijl

    Citation: BMC Endocrine Disorders 2020 20:94

    Content type: Study protocol

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  27. The uptake of continuous subcutaneous insulin infusion (CSII) therapy in those with type 1 diabetes varies internationally and is mainly determined by the national healthcare reimbursement systems. The aim of ...

    Authors: Katarzyna Anna Gajewska, Kathleen Bennett, Regien Biesma and Seamus Sreenan

    Citation: BMC Endocrine Disorders 2020 20:92

    Content type: Research article

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  28. After years of decline, the rate of amputations was reported to increase by 50% in the U.S. population between 2009 and 2015. Few studies have examined the most recent trends in hospitalized diabetic foot ulce...

    Authors: Yotsapon Thewjitcharoen, Jeeraphan Sripatpong, Sirinate Krittiyawong, Sriurai Porramatikul, Taweesak Srikummoon, Somkiet Mahaudomporn, Siriwan Butadej, Soontaree Nakasatien and Thep Himathongkam

    Citation: BMC Endocrine Disorders 2020 20:89

    Content type: Research article

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  29. This study aimed to measure the effect of diabetes education using the novel method of “diabetes conversation map (DCM)” as compared to routine counselling (RC) on diabetes management self-efficacy (DMSE) amon...

    Authors: Rubina Qasim, Sarfaraz Masih, Mohammad Tahir Yousafzai, Hakim shah, Abdul Manan, Yousaf Shah, Muhammad Yaqoob, Abida Razzaq, Ajmal Khan and Atiya Rahman Khan Rohilla

    Citation: BMC Endocrine Disorders 2020 20:88

    Content type: Research article

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  30. A well-known metabolic side effect from treatment with glucocorticoids is glucocorticoid-induced diabetes mellitus (GIDM). Guidelines on the management of GIDM in hospitalized patients (in the non-critical car...

    Authors: Carina Kirstine Klarskov, Helga Holm Schultz, Frederik Persson, Tomas Møller Christensen, Thomas Peter Almdal, Ole Snorgaard, Katrine Bagge Hansen, Ulrik Pedersen-Bjergaard and Peter Lommer Kristensen

    Citation: BMC Endocrine Disorders 2020 20:86

    Content type: Study protocol

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  31. Worldwide, the prevalence of insulin resistance ranges from 15.5 to 46.5%, among adults. Lebanon reported one of the highest rates reaching 44.6%. The literature suggests an association between dairy product c...

    Authors: Myriam Fahed, Maya G. Abou Jaoudeh, Samar Merhi, Jocelyne Matar Bou Mosleh, Rachelle Ghadieh, Sibelle Al Hayek and Jessy E. El Hayek Fares

    Citation: BMC Endocrine Disorders 2020 20:85

    Content type: Research article

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  32. Obesity and diabetes are related conditions, the prevalence of which has increased globally in recent years. These conditions have been linked to hypertension and vitamin D deficiency though the nature of the ...

    Authors: Ibrahim Al-Sumaih, Brian Johnston, Michael Donnelly and Ciaran O’Neill

    Citation: BMC Endocrine Disorders 2020 20:81

    Content type: Research article

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  33. Nonalcoholic fatty liver disease (NAFLD) is a multisystem disease that affects the liver and a variety of extra-hepatic organ systems. This study aimed to investigate the relationship between hepatic steatosis...

    Authors: Lijun Hu, Xiaoliang Shao, Chun Qiu, Xiaonan Shao, Xiaosong Wang, Rong Niu and Yuetao Wang

    Citation: BMC Endocrine Disorders 2020 20:75

    Content type: Research article

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  34. We quantified, among diabetic adults, the frequency, costs, and factors associated with visits to the emergency department (EDs) and subsequent hospitalizations for acute hypoglycaemic and hyperglycaemic events.

    Authors: Anita Andreano, Marco Bosio and Antonio Giampiero Russo

    Citation: BMC Endocrine Disorders 2020 20:72

    Content type: Research article

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  35. P-selectin, encoded by SELP, has been implicated as an important molecule in the development of arterial stiffness, consequently leading to vascular complications in T2DM. SELP polymorphisms and increased levels ...

    Authors: Raminderjit Kaur, Jatinder Singh, Rohit Kapoor and Manpreet Kaur

    Citation: BMC Endocrine Disorders 2020 20:70

    Content type: Research article

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  36. Insulin resistance (IR) is a common characteristic of women with polycystic ovary syndrome (PCOS). It has been reported that circulating Fetuin-A levels were associated with IR and type 2 diabetes mellitus (T2...

    Authors: Sha Liu, Wenjing Hu, Yirui He, Ling Li, Hua Liu, Lin Gao, Gangyi Yang and Xin Liao

    Citation: BMC Endocrine Disorders 2020 20:67

    Content type: Research article

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  37. The aim of this study was to estimate the levels of circulating carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) in subjects with gestational diabetes mellitus (GDM) and investigate the rela...

    Authors: Yiming Wu, Zhen Yang, Lingfei Zhu, Qing Su and Li Qin

    Citation: BMC Endocrine Disorders 2020 20:66

    Content type: Research article

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  38. Vitamin D measurement is a composite of vitamin D2 (25(OH)D2) and D3 (25(OH)D3) levels, and its deficiency is associated with the development of type 2 diabetes (T2DM) and diabetic complications; vitamin D defici...

    Authors: Lina H. M. Ahmed, Alexandra E. Butler, Soha R. Dargham, Aishah Latif, Amal Robay, Omar M. Chidiac, Amin Jayyousi, Jassim Al Suwaidi, Ronald G. Crystal, Stephen L. Atkin and Charbel Abi Khalil

    Citation: BMC Endocrine Disorders 2020 20:65

    Content type: Research article

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  39. Glucocorticoid (GC)-induced hyperglycemia is characterized by elevated postprandial blood glucose, which commonly requires multiple insulin injections. We investigated whether a long-acting glucagon-like pepti...

    Authors: Hiroyuki Uchinuma, Masashi Ichijo, Noriyuki Harima and Kyoichiro Tsuchiya

    Citation: BMC Endocrine Disorders 2020 20:58

    Content type: Research article

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  40. The relationship between betatrophin/ANGPTL8 and obesity has been investigated using body mass index (BMI); however, since BMI reflects overall adiposity rather than body fat distribution, it remains unclear w...

    Authors: Jing Zheng, Juan Liu, Beverly S. Hong, Weijian Ke, Minmin Huang and Yanbing Li

    Citation: BMC Endocrine Disorders 2020 20:51

    Content type: Research article

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  41. Diabetes mellitus (DM) is a global health care problem that can impose a substantial economic burden. Diabetic peripheral neuropathy (DPN) is a common microvascular complication of DM that increases the potent...

    Authors: Wondimeneh Shibabaw Shiferaw, Tadesse Yirga Akalu, Yeshamble Work and Yared Asmare Aynalem

    Citation: BMC Endocrine Disorders 2020 20:49

    Content type: Research article

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  42. Diabetic foot ulcers (DFUs) are common problems in diabetes. One of the most important factors affecting the quality of diabetes care is knowledge and practice. The current study aimed at determining the knowl...

    Authors: Aydin Pourkazemi, Atefeh Ghanbari, Monireh Khojamli, Heydarali Balo, Hossein Hemmati, Zakiyeh Jafaryparvar and Behrang Motamed

    Citation: BMC Endocrine Disorders 2020 20:40

    Content type: Research article

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  43. Various guidelines recommend that all adults diagnosed with type 1 diabetes (T1D) should be offered an evidence based, structured education programme (SEP) to optimize self-management care. China has a 13,000 ...

    Authors: Yuting Xie, Fang Liu, Fansu Huang, Chunna Lan, Jia Guo, Jing He, Lezhi Li, Xia Li and Zhiguang Zhou

    Citation: BMC Endocrine Disorders 2020 20:37

    Content type: Research article

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  44. There is evidence of statin benefit among patients with diabetes regardless of cholesterol levels or prior cardiovascular disease history. Despite the evidence, there is under-prescription of statins in clinic...

    Authors: Julius Chacha Mwita, Brian Godman and Tonya M. Esterhuizen

    Citation: BMC Endocrine Disorders 2020 20:36

    Content type: Research article

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  45. Hypoglycemia in type 2 diabetes mellitus (T2DM) is still unsolved issue. The aim of this study was to investigate hypoglycemia in T2DM in participants treated with oral antihyperglycemic agents using different...

    Authors: Maja Baretić and Valeria Bralić Lang

    Citation: BMC Endocrine Disorders 2020 20:35

    Content type: Research article

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  46. In contrast to insulin-dependent type 1 diabetes mellitus (T1DM), the indication for Simultaneous pancreas-kidney transplantation (SPK) in patients with type 2 diabetes mellitus (T2DM) is still ambiguous and w...

    Authors: Hans-Michael Hau, Nora Jahn, Maximilian Brunotte, Andri Arnosson Lederer, Elisabeth Sucher, Franz Maximilian Rasche, Daniel Seehofer and Robert Sucher

    Citation: BMC Endocrine Disorders 2020 20:30

    Content type: Research article

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  47. The number of patients with obesity continues to increase in our society. At the same time, digitalization defines our everyday life. Therefore, the question arises whether to use digital media for effective t...

    Authors: Alexandra Ziegeldorf, Petra Wagner and Hagen Wulff

    Citation: BMC Endocrine Disorders 2020 20:28

    Content type: Research article

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