Skip to main content

Bone and Thyroid

This section concerns disorders pertaining to bone and the thyroid; Articles concerning prevention, diagnosis and management, as well as related molecular genetics, and physiology are considered within this section.

  1. Low free triiodothyronine (FT3) levels are related to a poor prognosis deterioration in patients with COVID-19 presenting with non-thyroidal illness syndrome (NTI). This study was designed to explore whether f...

    Authors: Jing Gong, Ding-kun Wang, Hui Dong, Qing-song Xia, Zhao-yi Huang, Yan Zhao, Xing Chen, Fen Yuan, Jing-bin Li and Fu-er Lu

    Citation: BMC Endocrine Disorders 2021 21:111

    Content type: Research article

    Published on:

  2. Pseudohypoaldosteronism type II (PHAII), also called Gordon syndrome, is a rare hereditary disease caused by variants in the WNK1, WNK4, KLHL3 and CUL3 genes. The combination of PHAII with hyperthyroidism and sec...

    Authors: Rui Zhang, Simin Zhang, Yingying Luo, Meng Li, Xin Wen, Xiaoling Cai, Xueyao Han and Linong Ji

    Citation: BMC Endocrine Disorders 2021 21:103

    Content type: Case report

    Published on:

  3. Hypercalcemia associated with acromegaly is mostly parathyroid hormone (PTH)-dependent, being caused by parathyroid hyperplasia or adenoma, which are common in individuals with multiple endocrine adenomatosis-...

    Authors: Shaomin Shi, Lan Zhang, Yerong Yu, Chun Wang and Jianwei Li

    Citation: BMC Endocrine Disorders 2021 21:90

    Content type: Case report

    Published on:

  4. B lymphocyte activating factor (BAFF) is a growth factor regulating B lymphocytes survival and maturation. Serum BAFF levels were elevated in patients affected with autoimmune thyroid diseases (AITD), includin...

    Authors: Xin Wang, Jinhui Huang, Aixia Zhang, Chen Fang, Qi Ma and Pengjun Jiang

    Citation: BMC Endocrine Disorders 2021 21:88

    Content type: Research article

    Published on:

  5. As the incidence of secretory osteoporosis has increased, bone loss, osteoporosis and their relationships with thyroid-stimulating hormone (TSH) have received increased attention. In this study, the role of TS...

    Authors: Tuo Deng, Wenwen Zhang, Yanling Zhang, Mengqi Zhang, Zhikun Huan, Chunxiao Yu, Xiujuan Zhang, Yan Wang and Jin Xu

    Citation: BMC Endocrine Disorders 2021 21:49

    Content type: Research article

    Published on:

  6. Subclinical hypothyroidism (SCH) is reportedly associated with an increased risk of adverse events in patients undergoing percutaneous coronary intervention (PCI). The prognostic significance of SCH in the eld...

    Authors: Yong-Sheng Liu, Mei Wei, Le Wang, Gang Liu, Guo-Ping Ma, Katsushige Ono, Ze-Long Cao, Man Yang and Ming-Qi Zheng

    Citation: BMC Endocrine Disorders 2021 21:43

    Content type: Research article

    Published on:

  7. The incidence of thyroid nodules is increasing year by year around the world. However, ultrasound is not recommended as a screening test for the general population or patients with a normal thyroid on palpatio...

    Authors: Zhi Chen, Singla Sethiel Mosha, Tong Zhang, Ming Xu, Yanli Li, Zhuoqing Hu, Weiqiang Liang, Xiaoyi Deng, Tingting Ou, Ling Li and Wangen Li

    Citation: BMC Endocrine Disorders 2021 21:38

    Content type: Research article

    Published on:

  8. Levothyroxine replacement therapy may decrease the risk of adverse pregnancy outcomes among women with subclinical hypothyroidism (SCH). The aim of this study is to conduct a systematic review and meta-analysi...

    Authors: Magnus Bein, Oriana Hoi Yun Yu, Sonia Marzia Grandi, Francesca Y. E. Frati, Ihab Kandil and Kristian B. Filion

    Citation: BMC Endocrine Disorders 2021 21:34

    Content type: Research article

    Published on:

  9. Although thyroid function has been demonstrated to be associated with non-alcoholic fatty liver disease (NAFLD) in different population, the prevalence and features of NAFLD in hyperthyroidism have not been re...

    Authors: Bairong Wang, Baomin Wang, Yumei Yang, Jing Xu, Mengyang Hong, Mingfeng Xia, Xiaomu Li and Xin Gao

    Citation: BMC Endocrine Disorders 2021 21:27

    Content type: Research article

    Published on:

  10. Familial hypocalciuric hypercalcemia (FHH) is a heterogeneous autosomal-dominant disorder of calcium hemostasis that may be difficult to distinguish clinically from mild primary hyperparathyroidism. Loss-of-fu...

    Authors: Noha N Mukhtar, Mohei El-Din M Abouzied, Mohammed H Alqahtani and Muhammad M Hammami

    Citation: BMC Endocrine Disorders 2021 21:20

    Content type: Case report

    Published on:

  11. Long-term antithyroid drug therapy has become one of the options for treatment of Graves’ hyperthyroidism. The aim of this study was to compare thyroid status in those who discontinued methimazole (MMI) treatm...

    Authors: Fereidoun Azizi, Hengameh Abdi and Atieh Amouzegar

    Citation: BMC Endocrine Disorders 2021 21:16

    Content type: Research article

    Published on:

  12. Pseudohypoparathyroidism is a rare genetic disease characterized by hypocalcaemia and hyperphosphataemia due to the defect to the guanine nucleotide-binding protein alpha subunit (GNAS) gene. Patients with pse...

    Authors: Difei Lu, Aimei Dong, Junqing Zhang and Xiaohui Guo

    Citation: BMC Endocrine Disorders 2021 21:12

    Content type: Case report

    Published on:

  13. Multiple pathological manifestations are rarely present in patients with primary hyperparathyroidism (PHPT). Here we described a case of a young woman who presented with multiple skeletal destructions and rece...

    Authors: Shuai Lu, Maoqi Gong, Yejun Zha, Aimin Cui, Wei Tian and Xieyuan Jiang

    Citation: BMC Endocrine Disorders 2021 21:5

    Content type: Case report

    Published on:

  14. Thyroid associated orbitopathy (TAO) is the most common extrathyroidal complication of Graves’ disease. The disease course ranges from mild, where symptomatic therapy is sufficient, to severe, where high dose ...

    Authors: Janos K. Aranyosi, Tamas Deli, Annamaria Erdei, Geza Toth, Attila Jakab, Mariann Fodor, Endre V. Nagy and Bernadett Ujhelyi

    Citation: BMC Endocrine Disorders 2020 20:183

    Content type: Case report

    Published on:

  15. Thyroid associated orbitopathy (TAO) is defined as an immune mediated inflammatory process affecting the extraocular muscles, connective and adipose tissue of uncertain etiopathogenesis. TAO are classically de...

    Authors: Radwan El Othman, Christelle Ephrem, Elsie Touma, Souheil Hallit and Rola El Othman

    Citation: BMC Endocrine Disorders 2020 20:176

    Content type: Case report

    Published on:

  16. Microalbuminuria is a prognostic marker of diabetes kidney disease. It is generally diagnosed as the ratio of urinary albumin to creatinine (UACR) of 30-300 mg/g. Hashimoto’s thyroiditis is a common disease in...

    Authors: Wei Zhu, Xuejie Dong, Qingrong Pan, Yanjin Hu and Guang Wang

    Citation: BMC Endocrine Disorders 2020 20:172

    Content type: Research article

    Published on:

  17. Glucocorticoid therapy is the most common cause of iatrogenic osteoporosis. Less is known regarding the effect of glucocorticoids when used as replacement therapy on bone remodelling in patients with adrenal i...

    Authors: Rosemary Dineen, Lucy-Ann Behan, Grainne Kelleher, Mark J. Hannon, Jennifer J. Brady, Bairbre Rogers, Brian G. Keevil, William Tormey, Diarmuid Smith, Christopher J. Thompson, Malachi J. McKenna, Wiebke Arlt, Paul M. Stewart, Amar Agha and Mark Sherlock

    Citation: BMC Endocrine Disorders 2020 20:154

    Content type: Research article

    Published on:

  18. Low dose naltrexone (LDN) is reported to have beneficial effects in several autoimmune diseases. The purpose of this study was to examine whether starting LDN was followed by changes in the dispensing of thyro...

    Authors: Guttorm Raknes and Lars Småbrekke

    Citation: BMC Endocrine Disorders 2020 20:151

    Content type: Research article

    Published on:

  19. Graves’ disease is the commonest cause of thyrotoxicosis whilst thyrotropin (TSH)-producing pituitary adenomas (thyrotropinomas, TSHomas) are very rare and account for just 1–2% of all pituitary adenomas. Coex...

    Authors: Mark Quinn, Waiel Bashari, Diarmuid Smith, Mark Gurnell and Amar Agha

    Citation: BMC Endocrine Disorders 2020 20:133

    Content type: Case report

    Published on:

  20. Immune checkpoint inhibitors (ICIs) can induce immune-related adverse events (irAEs) including thyroid dysfunction. There are only a few reports on Graves’ disease induced by ICIs. We report a case of new-onse...

    Authors: Hiroshi Yamada, Fumitaka Okajima, Takeshi Onda, Shunji Fujimori, Naoya Emoto and Hitoshi Sugihara

    Citation: BMC Endocrine Disorders 2020 20:132

    Content type: Case report

    Published on:

  21. Basedow’s disease and Hashimoto’s thyroiditis are autoimmune thyroid disorders and usually diagnosed with elevation of serum autoimmune antibodies. Thyrotropin receptor antibodies (TRAb) and/or thyroid-stimula...

    Authors: Megumi Horiya, Takatoshi Anno, Fumiko Kawasaki, Yuichiro Iwamoto, Shintaro Irie, Yasumasa Monobe, Koichi Tomoda, Kohei Kaku, Shuhei Nakanishi and Hideaki Kaneto

    Citation: BMC Endocrine Disorders 2020 20:120

    Content type: Case report

    Published on:

  22. Acromegaly patients managed on Somatostatin receptor ligands (SRLs), the most common first-line pharmacotherapy for acromegaly, may still experience acromegaly symptoms such as headache, sweating, fatigue, sof...

    Authors: Eliza B. Geer, Jill Sisco, Daphne T. Adelman, William H. Ludlam, Asi Haviv, Shuqian Liu, Susan D. Mathias, Dana Gelbaum and Lizheng Shi

    Citation: BMC Endocrine Disorders 2020 20:117

    Content type: Research article

    Published on: