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BMC Endocrine Disorders

Basic and Clinical Endocrinology

Section edited by Amar Agha

This section concerns disorders of the pituitary axis and related organs and tissues; incuding specific disorders of the thyroid, adrenals, gonads etc. Articles concerning prevention, diagnosis and management, as well as related molecular genetics, and pathophysiology are considered within this section.

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  1. Content type: Research article

    Vitamin D (VitD) and parathyroid hormone (PTH) play important roles in calcium metabolism and skeletal homeostasis. Estimates of the VitD status in several European countries show large variations between them...

    Authors: Luís Raposo, Sandra Martins, Daniela Ferreira, João Tiago Guimarães and Ana Cristina Santos

    Citation: BMC Endocrine Disorders 2017 17:71

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  2. Content type: Case report

    Slipped capital femoral epiphysis (SCFE) is a common hip disorder characterized by displacement of the capital femoral epiphysis from the metaphysic through the femoral epiphyseal plate. SCFE usually occurs du...

    Authors: Saori Kadowaki, Tomohiro Hori, Hideki Matsumoto, Kaori Kanda, Michio Ozeki, Yu Shirakami, Norio Kawamoto, Hidenori Ohnishi and Toshiyuki Fukao

    Citation: BMC Endocrine Disorders 2017 17:59

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  3. Content type: Research article

    This study aimed to investigate preoperative somatostatin analogs (SSAs) treatment on the surgical outcome in patients with acromegaly.

    Authors: Lian Duan, Huijuan Zhu, Bing Xing and Feng Gu

    Citation: BMC Endocrine Disorders 2017 17:55

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  4. Content type: Case report

    A functional pituitary adenoma can produce multiple anterior-pituitary hormones, such as growth hormone (GH) -producing adenomas (GHoma) with prolactin or thyrotropin stimulating hormone production in the same...

    Authors: Tomoko Takiguchi, Hisashi Koide, Hidekazu Nagano, Akitoshi Nakayama, Masanori Fujimoto, Ai Tamura, Eri Komai, Akina Shiga, Takashi Kono, Seiichiro Higuchi, Ikki Sakuma, Naoko Hashimoto, Sawako Suzuki, Yui Miyabayashi, Norio Ishiwatari, Kentaro Horiguchi…

    Citation: BMC Endocrine Disorders 2017 17:54

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  5. Content type: Study protocol

    dsd-LIFE is a comprehensive cross-sectional clinical outcome study of individuals with disorders/differences of sex development (DSD). This study focuses on various rare genetic conditions characterized by imp...

    Authors: Robert Röhle, Katharina Gehrmann, Maria Szarras-Czapnik, Hedi Claahsen-van der Grinten, Catherine Pienkowski, Claire Bouvattier, Peggy Cohen-Kettenis, Anna Nordenström, Ute Thyen and Birgit Köhler

    Citation: BMC Endocrine Disorders 2017 17:52

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  6. Content type: Research article

    Primary adrenal insufficiency (PAI) is a rare and severe condition requiring lifelong steroid replacement. During acute illness or stressful events, it is important to appropriately adjust glucocorticoid dose;...

    Authors: L. M Shepherd, A. A Tahrani, C Inman, W Arlt and D. M Carrick-Sen

    Citation: BMC Endocrine Disorders 2017 17:47

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  7. Content type: Case report

    Primary hyperparathyroidism (PHPT) is uncommon among children with an incidence of 1:300,000. This diagnosis is often missed in children in contrast to adults where it is detected at a pre symptomatic stage du...

    Authors: Maulee Hiromi Arambewela, Kamani Danushka Liyanarachchi, Noel P. Somasundaram, Aruna S. Pallewatte and Gamini L. Punchihewa

    Citation: BMC Endocrine Disorders 2017 17:45

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  8. Content type: Research article

    Evidence suggests that endocannabinoid system activation through the cannabinoid receptor 1 (CB1) is associated with enhanced liver injury, and CB1 antagonism may be beneficial. The aim of this study was to de...

    Authors: Alison J. Dawson, Eric S. Kilpatrick, Anne-Marie Coady, Abeer M. M. Elshewehy, Youssra Dakroury, Lina Ahmed, Stephen L. Atkin and Thozhukat Sathyapalan

    Citation: BMC Endocrine Disorders 2017 17:41

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  9. Content type: Research article

    Communication is complex in endocrine care, particularly during transition from paediatric to adult services. The aims of this study were to examine the feasibility of interventions to support young people to ...

    Authors: J. Downing, H. Gleeson, P.E. Clayton, J.R.E. Davis, P. Dimitri, J. Wales, B. Young and P. Callery

    Citation: BMC Endocrine Disorders 2017 17:33

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  10. Content type: Research article

    Androsterone glucuronide (ADTG) concentrations have been suggested as a marker of the effects of androgens at the target tissue level. As the mechanism for hyperandrogenemia in obese and nonobese polycystic ov...

    Authors: Li-Wei Cho, Thozhukat Sathyapalan, Eric S Kilpatrick, Brian G Keevil, Adrian G Miller, Anne M Coady, Lina Ahmed and Stephen L Atkin

    Citation: BMC Endocrine Disorders 2017 17:26

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  11. Content type: Case report

    Congenital combined pituitary hormone deficiency (CPHD) is a rare heterogeneous group of conditions. CPHD-type 3 (CPHD3; MIM# 221750) is caused by recessive mutations in LHX3, a LIM-homeodomain transcription fact...

    Authors: Khushnooda Ramzan, Bassam Bin-Abbas, Lolwa Al-Jomaa, Rabab Allam, Mohammed Al-Owain and Faiqa Imtiaz

    Citation: BMC Endocrine Disorders 2017 17:17

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  12. Content type: Research article

    Nonalcoholic fatty liver disease (NAFLD) is considered a critical hepatic manifestation of metabolic syndrome. Berberine (BBR) exerts anti-hyperglycemic and anti-dyslipidemic effects and can also ameliorate NA...

    Authors: Li Zhao, Zhen Cang, Honglin Sun, Xiaomin Nie, Ningjian Wang and Yingli Lu

    Citation: BMC Endocrine Disorders 2017 17:13

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  13. Content type: Research article

    Vitamin D (D) supplements are indispensable for its world-wide deficiency. Controversy continues on ergocalciferol (D2) and cholecalciferol (D3) relative potency as well as on dosing-schedule and sex role in r...

    Authors: Muhammad M. Hammami and Ahmed Yusuf

    Citation: BMC Endocrine Disorders 2017 17:12

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  14. Content type: Research article

    MST-4 and TRAF-6 are involved in the regulation of inflammatory and immune responses. However, whether they participate in the pathogenesis of Graves’ disease (GD) has not yet been reported. Therefore, the pur...

    Authors: Ai Guo, Yan Tan, Chun Liu and Xiaoya Zheng

    Citation: BMC Endocrine Disorders 2017 17:11

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  15. Content type: Research article

    Subclinical hypothyroidism (SH) is associated with adverse obstetric outcomes and neurodevelopment disorders. Both iodine deficiency and excess are associated with SH; however, few data regarding iodine nutrit...

    Authors: Kunling Wang, Jie Zhang, Fengao Li, Wanqi Zhang, Hao Wang, Li Ding, Yaxin Liu, Laixiang Lin, Shuang Zhang and Mei Zhu

    Citation: BMC Endocrine Disorders 2017 17:10

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  16. Content type: Research article

    Liraglutide 3 mg was recently approved as an anti-obesity drug. Metformin is weight neutral, yet it could enhance the therapeutic index of GLP-1 agonist. We compared weight-lowering potential of liraglutide 1....

    Authors: Mojca Jensterle, Nika Aleksandra Kravos, Katja Goričar and Andrej Janez

    Citation: BMC Endocrine Disorders 2017 17:5

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  17. Content type: Research article

    To determine the diagnostic efficacy of ultrasonographic malignancy risk features (UMRFs) in follicular lesions (FL) in a population with low risk of malignancy in FL and to compare it with a similar analysis ...

    Authors: Dorota Słowińska-Klencka, Martyna Wojtaszek-Nowicka, Stanisław Sporny, Ewa Woźniak-Oseła, Bożena Popowicz and Mariusz Klencki

    Citation: BMC Endocrine Disorders 2016 16:69

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  18. Content type: Case report

    Growth hormone deficiency (GHD) is associated with non-alcoholic fatty liver disease (NAFLD). A recent animal study showed that hepatocyte-specific receptor activator of nuclear factor-kappa B (RANK) knockout ...

    Authors: Ayumu Takeno, Masahiro Yamamoto, Masakazu Notsu and Toshitsugu Sugimoto

    Citation: BMC Endocrine Disorders 2016 16:66

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