Skip to main content

Table 7 Uni- and multivariable Hazard Cox regression survival analysis in the CD8 negative TCGA-cohort (n = 238)

From: The prognostic significance of CXCR4 and SDF-1 in differentiated thyroid cancer depends on CD8+ density

Characteristic

Univariable Analysis

Multivariable Analysis

Hazard Ratio

95% CI

P value

Hazard Ratio

95% CI

P value

Age (≥55 vs < 55)

 

1

  

Sex (Male vs female)

1.1

(0.29–4.4)

0.86

  

pT (high vs. low)

7.3

(1.5–34)

0.01

9.7

(1.1–84)

0.03

pN (1 vs. 0/x)

0.94

(0.26–3.4)

0.93

  

pM (1 vs. 0/x)

11

(2.3–52)

0.002

4.9

(0.9–26)

0.07

SDF1low/CXCR4low vs SDF1high/CXCR4high

0.21

(0.05–0.84)

0.03

0.2

(0.04–0.7)

0.02

SDF1low/CXCR4low vs SDF1low/CXCR4high

1.4

(0.25–7.5)

0.71

  

SDF1low/CXCR4low vs. SDF1high/CXCR4low

 

1

  
  1. Variables significant (p < 0.05) in univariate analyses were included in multivariate Cox regression analysis