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Table 6 Uni- and multivariable Hazard Cox regression survival analysis in the TCGA-cohort (n = 456)

From: The prognostic significance of CXCR4 and SDF-1 in differentiated thyroid cancer depends on CD8+ density

Characteristic

Univariable Analysis

Multivariable Analysis

Hazard Ratio

95% CI

P value

Hazard Ratio

95% CI

P value

Age (≥55 vs < 55)

3.1

 

1

  

Sex (Male vs female)

2.1

(0.75–5.7)

0.16

  

pT (high vs. low)

3.3

(1.1–9.6)

0.03

3.1

(1.1–8.9)

0.04

pN (1 vs. 0/x)

1.2

(0.45–3.2)

0.73

  

pM (1 vs. 0/x)

4.7

(1.1–21)

0.04

3.7

(0.8–16)

0.08

SDF1low/CXCR4low vs. SDF1high/CXCR4high

0.7

(0.22–2.2)

0.54

  

SDF1low/CXCR4low vs. SDF1low/CXCR4high

1.9

(0.64–1.1)

0.24

  

SDF1low/CXCR4low vs. SDF1high/CXCR4low

3.6

(0.97–1)

0.86

  
  1. Variables significant (p < 0.05) in univariate analyses were included in multivariate Cox regression analysis