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Table 2 Comparison of blood test measurements of individuals categorized according to the extent of their weight loss

From: Serum TSH, 25(OH) D and phosphorus levels predict weight loss in individuals with diabetes/prediabetes and morbid obesity: a single-center retrospective cohort analysis

 

Weight loss ≥10%,

(n = 61)

Weight loss < 10%, (n = 162)

Weight gain,

(n = 62)

p-value **

p-value **

First visit

Last visit

p-value*

First visit

Last visit

p-value*

First visit

Last visit

p-value*

between groups, first visit

Between groups, last visit

TSH (μIU/L)

1.3 (1.0–2.1)

1.2 (0.8–1.5)

<.001

1.5 (1.1–2.2)

1.3 (0.9–1.7)

<.001

1.6 (1.1–2.1)

1.4 (1.1–2.0)

.058

.346

.009

fT4 (pmol/L)

13.2 (12.3–14.5)

13.9 (12.6–15.0)

.018

13.1 (12.2–14.2)

13.6 (12.4–14.7)

.042

12.7 (11.6–14.1)

13.3 (12.2–14.7)

.112

.357

.225

fT3 (pmol/L)

4.2 (3.6–4.7)

4.1 (3.8–4.7)

.422

4.2 (3.9–4.7)

4.3 (4.0–4.8)

.089

4.4 (4.1–4.8)

4.3 (4.0–4.8)

.907

.069

.347

SPINA-GD (nmol/s)

28 (23–33)

28 (24–32)

.755

30 (26–33)

30 (26–34)

.770

31 (28–37)

30 (26–34)

.221

.058

.137

SPINA-GT (pmol/s)

3.7 (2.8–4.3)

3.6 (3.1–4.6)

.894

3.2 (2.5–4.0)

3.3 (2.6–4.3)

.443

3.0 (2.2–3.9)

3.3 (2.3–3.8)

.904

.145

.059

Calcium (mg/dL)

9.2 (9.0–9.4)

9.6 (9.3–10.0)

<.001

9.1 (8.9–9.5)

9.5 (9.2–9.7)

<.001

9.1 (8.7–9.4)

9.5 (9.1–9.8)

<.001

.559

.058

Phosphorus (mg/dL)

3.5 (3.0–3.7)

3.7 (3.4–4.1)

<.001

3.4 (3.1–3.7)

3.5 (3.2–3.9)

<.001

3.4 (3.1–3.6)

3.3 (3.1–3.7)

.480

.877

.002

Parathormone (pg/mL)

72 (59–92)

62 (49–74)

.001

75 (51–99)

64 (48–82)

<.001

66 (51–98)

79 (61–95)

.572

.803

.004

25(OH)D (nmol/L)

31 (19–45)

64 (46–78)

<.001

34 (22–48)

55 (41–69)

<.001

40 (23–54)

47 (30–56)

.174

.278

<.001

Follow-up duration (months)

22 (13–43)

20 (11–33)

24 (14–34)

.145**

Levothyroxine replacement, n = 109 (%)

24 (39.3)

65 (40.1)

20 (32.3)

.545***

Anti-thyroid antibody positivity, n = 64 (%)

13 (21.3)

33 (20.4)

18 (29.0)

.370***

  1. *Comparisons were performed by Wilcoxon signed rank test
  2. **Comparisons were performed by Kruskal-Wallis test
  3. ***Comparisons were performed by Pearson’s Chi-square