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Table 4 Association of comorbidities with all-cause mortality in Type 2 DM patients

From: Epidemiology of type 1 and type 2 diabetes mellitus in Kazakhstan: data from unified National Electronic Health System 2014–2019

Variables

Crude HR and 95% CI

p-value

Model 1a

Adjusted HR and 95% CI

p-value

Model 2b

Adjusted HR and 95% CI

p-value

Diabetic neuropathy, yes

0.58 (0.56–0.6)

< 0.001

0.76 (0.74–0.79)

< 0.001

0.81 (0.77–0.85)

< 0.001

Coronary artery disease, yes

0.78 (0.77–0.8)

< 0.001

0.85 (0.84–0.87)

< 0.001

1.04 (1.02–1.07)

< 0.001

Hypertension, yes

0.56 (0.55–0.57)

< 0.001

0.58 (0.57–0.59)

< 0.001

0.54 (0.53–0.55)

< 0.001

Diabetic nephropathy, yes

1.26 (1.21–1.32)

< 0.001

1.63 (1.56–1.71)

< 0.001

2.06 (1.96–2.16)

< 0.001

Retinopathy, yes

0.53 (0.51–0.56)

< 0.001

0.72 (0.69–0.76)

< 0.001

0.72 (0.68–0.77)

< 0.001

Stroke, yes

1.5 (1.45–1.56)

< 0.001

1.56 (1.51–1.62)

< 0.001

1.8 (1.73–1.87)

< 0.001

Diabetic foot, yes

1.13 (1.1–1.18)

< 0.001

1.32 (1.27–1.36)

< 0.001

1.23 (1.18–1.28)

< 0.001

Amputations, yes

1.79 (1.69–1.88)

< 0.001

1.95 (1.85–2.05)

< 0.001

1.64 (1.54–1.75)

< 0.001

Neoplasms, yes

1.31 (1.28–1.35)

< 0.001

1.3 (1.27–1.34)

< 0.001

1.37 (1.34–1.41)

< 0.001

  1. aModel 1 adjusted for sex, age categories and ethnicity
  2. bModel 2 adjusted for sex, age categories, ethnicity, diabetic neuropathy, coronary artery disease, hypertension, diabetic nephropathy, retinopathy, stroke, diabetic foot, amputations and neoplasms