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Table 1 Clinical and laboratory characteristics of the subjects in different groups

From: Irisin as a predictor of bone metabolism in Han Chinese Young Men with pre-diabetic individuals

variable

NGT group (n = 45)

Pre-diabetes group (n = 41)

t or χ2

P

Age (years) mean (SD)

37.1 (6.8)

37.8 (4.8)

-0.576

0.566

BMI (kg/m2) mean (SD)

26.8 (3.5)

29.1 (2.7)

-3.517

0.001

WC (cm) mean (SD)

93.4 (9.1)

97.7 (8.4)

-2.244

0.027

FPG (mmol/L) mean (SD)

5.2 (0.2)

5.8 (0.5)

-7.266

0.000

2 h-PG (mmol/L) mean (SD)

5.8 (0.9)

7.7 (1.9)

-5.743

0.000

TG (mmol/L) median (IQR)

1.24 (0.17)

1.56 (0.36)

-0.606

0.546

HDL-C (mmol/L) mean (SD)

1.38 (0.25)

1.24 (0.33)

3.715

0.000

FINS(uIU/mL) median (IQR)

10.73 (2.6)

11.93 (3.1)

-1.778

0.079

HOMA-IR median (IQR)

2.48 (0.62)

3.29 (1.04)

-2.905

0.005

InIR mean(SD)

0.9 (0.4)

1.2 (0.4)

-2.924

0.004

Irisin (µg/mL) mean (SD)

6.3 (1.5)

4.4 (1.4)

5.804

0.000

BMC (g) mean (SD)

3503.2 (1414.1)

4010.6 (1583.4)

-1.439

0.155

CTX (ng/mL) mean (SD)

1.0 (0.5)

1.4 (1.0)

-2.071

0.041

P1NP (ng/mL) mean (SD)

79.4 (34.8)

53.8 (45.0)

2.924

0.005

OC (ng/mL) mean (SD)

38.7 (3.5)

35.4 (4.4)

3.856

0.000

  1. Data are expressed as mean ± standard deviation (SD) or medians with interquartile ranges (IQR). When data was not normally distributed, they were ln transformed for analysis
  2. NGT normal glucose tolerance, BMI body mass index, WC waist circumference, FPG fasting plasma glucose, 2 h-PG 2 h plasma glucose, TG triglycerides, HDL-C high density lipoprotein cholesterol, FINS fasting insulin, HOMA-IR homeostasis model assessment of insulin resistance, BMC bone mineral content, CTX β-C-telopeptides of type I collagen, P1NP Procollagen 1 Amino-terminal Propeptide, OC Osteocalcin, SD standard deviation, IQR indicates interquartile range