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Table 2 The associations between prior antibiotic exposure (from 1993 to baseline) with body mass index

From: Use of antibiotics and risk of type 2 diabetes, overweight and obesity: the Cardiovascular Risk in Young Finns Study and the national FINRISK study

  

Age- and sex-adjusteda

Adjusted for risk factors b

  

β

±SE

P-value

β

±SE

P-value

Antibiotics

YFS

0.100

0.028

0.0004

0.058

0.023

0.01

FINRISK

0.063

0.005

< 0.0001

0.068

0.005

< 0.0001

Antifungals

YFS

0.055

0.079

0.49

−0.031

0.067

0.64

Antivirals

YFS

0.059

0.203

0.77

0.145

0.157

0.36

  1. Beta-values are per one prescribed course of systemic antimicrobial agents. Body mass index measured at baseline (1997, 2002, 2007, 2012) in FINRISK and at the most recent clinical follow-up (2011) in YFS
  2. SE Standard error, YFS The Cardiovascular Risk in Young Finns Study, FINRISK The national FINRISK study
  3. aFINRISK analyses adjusted additionally for study cohort
  4. bAdjusted for 1) age, sex, childhood family income, parental smoking and early life (age 6 to 24 years) insulin, systolic blood pressure, body mass index and physical activity in YFS. 2) age, sex, study cohort, income, smoking, systolic blood pressure, physical activity in FINRISK