Table 4 The genes in GO enrichment analysis of SDEGs in skeletal muscle of T2DM
Term | PValue | Genes |
|---|---|---|
BP-GO:0071493~cellular response to UV-B | 0.002344 | CDKN1A, CRIP1, HYAL3 |
BP-GO:0010838~positive regulation of keratinocyte proliferation | 0.002995 | FGF7, TP63, REG3G |
BP-GO:0071805~potassium ion transmembrane transport | 0.005586 | CCT8L2, KCNN2, KCNH6, KCNQ1, SLC9A1, KCNH5 |
CC-GO:0005615~extracellular space | 3.53E-04 | CSTL1, SERPINA10, FGF9, IL32, ANPEP, IGHM, MTHFD2, H2BFS, SCRG1, PROZ, SERPINA1, SEMA3A, PNLIPRP2, ADAMTS20, EFEMP1, RAB11FIP4, GCG, DKK3, ADAMTS9, UMODL1, SCGB1D2, NLGN4X, WFDC1, HSPD1, PYY, AOC1 |
CC-GO:0009986~cell surface | 0.001131 | IGHM, HYAL4, ADAMTS9, CD86, CD80, KCNN2, NLGN4X, CLEC2D, TMEM102, HSPD1, GHSR, DPP4, SLC9A1, KCNH5 |
CC-GO:0005576~extracellular region | 0.028126 | HYAL3, PNLIPRP2, FGF7, FGF9, EFEMP1, PGLYRP1, FSTL4, C17ORF77, GCG, LAMA2, DKK3, CALCB, BDNF, WFDC6, IL23A, PROZ, SFTA3, SERPINA1, HTRA4, SEMA3A, PYY, REG3G, CYR61 |
MF-GO:0005516~calmodulin binding | 0.008803 | MYO5A, MYH1, KCNN2, CAMK2A, KCNQ1, SLC9A1, KCNH5 |
MF-GO:0005509~calcium ion binding | 0.017294 | CDH12, RAB11FIP4, MYO5A, PNLIPRP2, UMODL1, TENM2, PROZ, EFEMP1, PLS1, FSTL4, PCDHB13, SYT16, CALML6, AOC1 |
MF-GO:0008270~zinc ion binding | 0.025422 | CRIP1, THRA, ADAMTS20, AGBL5, PGLYRP1, TRIM14, NR4A1, ZDHHC18, ANPEP, RNF187, RORA, TRIM23, TET2, ZNF3, ADAMTS9, ST18, AOC1, BAZ2A, TES |