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Table 3 Univariate and multivariate analyses of gallbladder cancer risk in GSD patients

From: Elevated serum triglyceride levels may be a key independent predicting factor for gallbladder cancer risk in gallbladder stone disease patients: a case–control study

Factors

 

Univariate

 

Multivariate (without HTG)

Multivariate (with HTG)

β

OR

95%CI

P value

β

OR

95%CI

P value

β

OR

95%CI

P value

Gender (F)

0.877

2.404

1.796 ~ 3.218

< 0.001

0.487

1.627

0.954 ~ 2.776

0.074

0.586

1.796

1.110 ~ 2.908

0.017

BMI

-0.009

0.991

0.953 ~ 1.031

0.662

-

-

-

-

-

-

-

-

TG

3.549

34.784

20.961 ~ 57.723

< 0.001

2.828

16.912

9.648 ~ 29.643

< 0.001

/

/

/

/

TC

-0.097

0.908

0.816 ~ 1.010

0.076

-

-

-

-

-

-

-

-

HDL-c

-0.326

0.722

0.633 ~ 0.823

< 0.001

-0.481

0.618

0.486 ~ 0.787

< 0.001

-0.407

0.665

0.537 ~ 0.824

< 0.001

LDL-c

1.845

6.331

4.894 ~ 8.189

< 0.001

1.205

3.338

2.476 ~ 4.498

< 0.001

1.442

4.230

3.172 ~ 5.641

< 0.001

HOMA-IR

1.148

3.153

2.587 ~ 3.842

< 0.001

0.968

2.633

2.022 ~ 3.428

< 0.001

0.878

2.407

1.892 ~ 3.063

< 0.001

DM

0.030

1.030

0.686 ~ 1.548

0.886

-

-

-

-

-

-

-

-

NAFLD

0.017

1.017

0.766 ~ 1.352

0.905

-

-

-

-

-

-

-

-

DBP

-0.054

0.947

0.934 ~ 0.960

< 0.001

/

/

/

/

/

/

/

/

SBP

-0.027

0.974

0.966 ~ 0.981

< 0.001

/

/

/

/

/

/

/

/

FINS

0.427

1.533

1.441 ~ 1.631

< 0.001

*

*

*

*

*

*

*

*

FBG

-0.079

0.924

0.860 ~ 0.994

0.034

*

*

*

*

*

*

*

*

HBP

-0.811

0.445

0.330 ~ 0.598

< 0.001

-0.934

0.393

0.226 ~ 0.682

0.001

-0.737

0.479

0.292 ~ 0.784

0.003

HTG

2.949

19.077

13.463 ~ 27.034

< 0.001

/

/

/

/

2.364

10.636

6.644 ~ 17.028

 < 0.001

  1. BMI Body mass index, TG Triglyceride, TC Total cholesterol, HDL-c High density lipoprotein cholesterol, LDL-c Low density lipoprotein cholesterol, NAFLD Nonalcoholic fatty liver disease, SBP Systolic blood pressure, DBP Diastolic blood pressure, FBG Fasting blood glucose, FINS Fasting blood insulin, HOMA-IR Homeostasis model assessment of insulin resistance, HBP High blood pressure, DM Diabetes mellitus
  2. *eliminated for the definition of HOMA-IR in multivariate regression
  3. — eliminated for no statistical significance in univariate regression
  4. / eliminated for the collinear/redundant correlation between SBP, DBP and HP; TG and HTG in multivariate regression